-
1
-
-
0003677259
-
-
Society AC, ed. (Atlanta: American Cancer Society)
-
American Cancer Society. (2015). Cancer Facts & Figures 2015 In: Society AC, ed. (Atlanta: American Cancer Society).
-
(2015)
Cancer Facts & Figures 2015
-
-
-
2
-
-
77649158894
-
NCCN clinical practice guidelines in oncology: prostate cancer
-
Mohler J, Bahnson RR, Boston B, Busby JE, D'Amico A, Eastham JA, Enke CA, George D, Horwitz EM, Huben RP, KantoffP, Kawachi M, Kuettel M, et al. NCCN clinical practice guidelines in oncology: prostate cancer. J Natl Compr Canc Netw. 2010; 8: 162-200. doi:
-
(2010)
J Natl Compr Canc Netw
, vol.8
, pp. 162-200
-
-
Mohler, J.1
Bahnson, R.R.2
Boston, B.3
Busby, J.E.4
D'Amico, A.5
Eastham, J.A.6
Enke, C.A.7
George, D.8
Horwitz, E.M.9
Huben, R.P.10
Kantoff, P.11
Kawachi, M.12
Kuettel, M.13
-
3
-
-
84969516736
-
Prostate Cancer, Version 1.2016
-
Mohler JL, Armstrong AJ, Bahnson RR, D'Amico AV, Davis BJ, Eastham JA, Enke CA, Farrington TA, Higano CS, Horwitz EM, Hurwitz M, Kane CJ, Kawachi MH, et al. Prostate Cancer, Version 1.2016. J Natl Compr Canc Netw. 2016; 14: 19-30. doi:
-
(2016)
J Natl Compr Canc Netw
, vol.14
, pp. 19-30
-
-
Mohler, J.L.1
Armstrong, A.J.2
Bahnson, R.R.3
D'Amico, A.V.4
Davis, B.J.5
Eastham, J.A.6
Enke, C.A.7
Farrington, T.A.8
Higano, C.S.9
Horwitz, E.M.10
Hurwitz, M.11
Kane, C.J.12
Kawachi, M.H.13
-
4
-
-
0013890366
-
Classification of prostatic carcinomas
-
Gleason DF. Classification of prostatic carcinomas. Cancer Chemother Rep. 1966; 50: 125-8. doi:
-
(1966)
Cancer Chemother Rep
, vol.50
, pp. 125-128
-
-
Gleason, D.F.1
-
5
-
-
0015950349
-
Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging
-
Gleason DF, Mellinger GT. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. J Urol. 1974; 111: 58-64. doi:
-
(1974)
J Urol
, vol.111
, pp. 58-64
-
-
Gleason, D.F.1
Mellinger, G.T.2
-
6
-
-
84958033425
-
The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma: Definition of Grading Patterns and Proposal for a New Grading System
-
Epstein JI, Egevad L, Amin MB, Delahunt B, Srigley JR, Humphrey PA, and the Grading C. The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma: Definition of Grading Patterns and Proposal for a New Grading System. Am J Surg Pathol. 2015. doi: 10.1097/PAS.0000000000000530.
-
(2015)
Am J Surg Pathol
-
-
Epstein, J.I.1
Egevad, L.2
Amin, M.B.3
Delahunt, B.4
Srigley, J.R.5
Humphrey, P.A.6
Grading, C.7
-
7
-
-
84888815889
-
EAU guidelines on prostate canc. part 1: screening, diagnosis, and local treatment with curative intent-update 2013
-
Heidenreich A, Bastian PJ, Bellmunt J, Bolla M, Joniau S, van der Kwast T, Mason M, Matveev V, Wiegel T, Zattoni F, Mottet N, European Association of U. EAU guidelines on prostate cancer. part 1: screening, diagnosis, and local treatment with curative intent-update 2013. Eur Urol. 2014; 65: 124-37. doi: 10.1016/j.eururo.2013.09.046.
-
(2014)
Eur Urol
, vol.65
, pp. 124-137
-
-
Heidenreich, A.1
Bastian, P.J.2
Bellmunt, J.3
Bolla, M.4
Joniau, S.5
van der Kwast, T.6
Mason, M.7
Matveev, V.8
Wiegel, T.9
Zattoni, F.10
Mottet, N.11
-
8
-
-
34250012314
-
Updated nomogram to predict pathologic stage of prostate cancer given prostate-specific antigen level, clinical stage, and biopsy Gleason score (Partin tables) based on cases from 2000 to 2005
-
Makarov DV, Trock BJ, Humphreys EB, Mangold LA, Walsh PC, Epstein JI, Partin AW. Updated nomogram to predict pathologic stage of prostate cancer given prostate-specific antigen level, clinical stage, and biopsy Gleason score (Partin tables) based on cases from 2000 to 2005. Urology. 2007; 69: 1095-101. doi: 10.1016/j. urology.2007.03.042.
-
(2007)
Urology
, vol.69
, pp. 1095-1101
-
-
Makarov, D.V.1
Trock, B.J.2
Humphreys, E.B.3
Mangold, L.A.4
Walsh, P.C.5
Epstein, J.I.6
Partin, A.W.7
-
9
-
-
67449126769
-
Risk assessment for prostate cancer metastasis and mortality at the time of diagnosis
-
Cooperberg MR, Broering JM, Carroll PR. Risk assessment for prostate cancer metastasis and mortality at the time of diagnosis. J Natl Cancer Inst. 2009; 101: 878-87. doi: 10.1093/jnci/djp122.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 878-887
-
-
Cooperberg, M.R.1
Broering, J.M.2
Carroll, P.R.3
-
10
-
-
84871706840
-
How to select the optimal therapy for early-stage prostate cancer
-
Kollmeier MA, Zelefsky MJ. How to select the optimal therapy for early-stage prostate cancer. Crit Rev Oncol Hematol. 2012; 84 Suppl 1: e6-e15. doi: 10.1016/j. critrevonc.2012.12.002.
-
(2012)
Crit Rev Oncol Hematol
, vol.84
, pp. e6-e15
-
-
Kollmeier, M.A.1
Zelefsky, M.J.2
-
11
-
-
84959521142
-
Active surveillance for prostate cancer
-
Romero-Otero J, Garcia-Gomez B, Duarte-Ojeda JM, Rodriguez-Antolin A, Vilaseca A, Carlsson SV, Touijer KA. Active surveillance for prostate cancer. Int J Urol. 2016; 23: 211-8. doi: 10.1111/iju.13016.
-
(2016)
Int J Urol
, vol.23
, pp. 211-218
-
-
Romero-Otero, J.1
Garcia-Gomez, B.2
Duarte-Ojeda, J.M.3
Rodriguez-Antolin, A.4
Vilaseca, A.5
Carlsson, S.V.6
Touijer, K.A.7
-
12
-
-
0037299787
-
Hormonal therapy: historical perspective to future directions
-
McLeod DG. Hormonal therapy: historical perspective to future directions. Urology. 2003; 61: 3-7. doi: 10.1016/S0090-4295(02)02393-2.
-
(2003)
Urology
, vol.61
, pp. 3-7
-
-
McLeod, D.G.1
-
13
-
-
84960355151
-
Therapeutic Rationales, Progresses, Failures, and Future Directions for Advanced Prostate Cancer
-
Wadosky KM, Koochekpour S. Therapeutic Rationales, Progresses, Failures, and Future Directions for Advanced Prostate Cancer. Int J Biol Sci. 2016; 12: 409-26. doi: doi:10.7150/ijbs.14090.
-
(2016)
Int J Biol Sci
, vol.12
, pp. 409-426
-
-
Wadosky, K.M.1
Koochekpour, S.2
-
14
-
-
84928580276
-
Studies on Prostatic Cancer. I. The Effect of Castration, of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate
-
Huggins C, Hodges C. Studies on Prostatic Cancer. I. The Effect of Castration, of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate. Cancer Research. 1941; 1: 293-7. doi:
-
(1941)
Cancer Research
, vol.1
, pp. 293-297
-
-
Huggins, C.1
Hodges, C.2
-
15
-
-
22144484150
-
Androgen deprivation therapy for prostate cancer
-
SharifiN, Gulley JL, Dahut WL. Androgen deprivation therapy for prostate cancer. JAMA. 2005; 294: 238-44. doi: 10.1001/jama.294.2.238.
-
(2005)
JAMA
, vol.294
, pp. 238-244
-
-
Sharifi, N.1
Gulley, J.L.2
Dahut, W.L.3
-
16
-
-
33746623315
-
Molecular regulation of androgen action in prostate cancer
-
Dehm SM, Tindall DJ. Molecular regulation of androgen action in prostate cancer. J Cell Biochem. 2006; 99: 333-44. doi: 10.1002/jcb.20794.
-
(2006)
J Cell Biochem
, vol.99
, pp. 333-344
-
-
Dehm, S.M.1
Tindall, D.J.2
-
17
-
-
84880009495
-
Castration-resistant prostate cancer: AUA Guideline
-
Cookson MS, Roth BJ, Dahm P, Engstrom C, Freedland SJ, Hussain M, Lin DW, Lowrance WT, Murad MH, Oh WK, Penson DF, Kibel AS. Castration-resistant prostate cancer: AUA Guideline. J Urol. 2013; 190: 429-38. doi: 10.1016/j. juro.2013.05.005.
-
(2013)
J Urol
, vol.190
, pp. 429-438
-
-
Cookson, M.S.1
Roth, B.J.2
Dahm, P.3
Engstrom, C.4
Freedland, S.J.5
Hussain, M.6
Lin, D.W.7
Lowrance, W.T.8
Murad, M.H.9
Oh, W.K.10
Penson, D.F.11
Kibel, A.S.12
-
18
-
-
84920748709
-
American Urological A. Castration-resistant prostate cancer: AUA guideline amendment
-
Cookson MS, Lowrance WT, Murad MH, Kibel AS, American Urological A. Castration-resistant prostate cancer: AUA guideline amendment. J Urol. 2015; 193: 491-9 doi: 10.1016/j.juro.2014.10.104.
-
(2015)
J Urol
, vol.193
, pp. 491-499
-
-
Cookson, M.S.1
Lowrance, W.T.2
Murad, M.H.3
Kibel, A.S.4
-
19
-
-
84962950760
-
Castration-Resistant Prostate Cancer: AUA Guideline Amendment 2015
-
Lowrance WT, Roth BJ, Kirkby E, Murad MH, Cookson MS. Castration-Resistant Prostate Cancer: AUA Guideline Amendment 2015. J Urol. 2016; 195: 1444-52. doi: 10.1016/j.juro.2015.10.086.
-
(2016)
J Urol
, vol.195
, pp. 1444-1452
-
-
Lowrance, W.T.1
Roth, B.J.2
Kirkby, E.3
Murad, M.H.4
Cookson, M.S.5
-
20
-
-
60149089419
-
Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion
-
Harris WP, Mostaghel EA, Nelson PS, Montgomery B. Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion. Nat Clin Pract Urol. 2009; 6: 76-85. doi: 10.1038/ncpuro1296.
-
(2009)
Nat Clin Pract Urol
, vol.6
, pp. 76-85
-
-
Harris, W.P.1
Mostaghel, E.A.2
Nelson, P.S.3
Montgomery, B.4
-
21
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A, Fizazi K, North S, Chu L, Chi KN, Jones RJ, Goodman OB, Jr., Saad F, Staffurth JN, Mainwaring P, Harland S, et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med. 2011; 364: 1995-2005. doi: 10.1056/NEJMoa1014618.
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
de Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
Fizazi, K.4
North, S.5
Chu, L.6
Chi, K.N.7
Jones, R.J.8
Goodman, O.B.9
Saad, F.10
Staffurth, J.N.11
Mainwaring, P.12
Harland, S.13
-
22
-
-
84872078210
-
Abiraterone in metastatic prostate cancer without previous chemotherapy
-
Ryan CJ, Smith MR, de Bono JS, Molina A, Logothetis CJ, de Souza P, Fizazi K, Mainwaring P, Piulats JM, Ng S, Carles J, Mulders PF, Basch E, et al. Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med. 2013; 368: 138-48. doi: 10.1056/NEJMoa1209096.
-
(2013)
N Engl J Med
, vol.368
, pp. 138-148
-
-
Ryan, C.J.1
Smith, M.R.2
de Bono, J.S.3
Molina, A.4
Logothetis, C.J.5
de Souza, P.6
Fizazi, K.7
Mainwaring, P.8
Piulats, J.M.9
Ng, S.10
Carles, J.11
Mulders, P.F.12
Basch, E.13
-
23
-
-
84904871070
-
Enzalutamide in metastatic prostate cancer before chemotherapy
-
Beer TM, Armstrong AJ, Rathkopf DE, Loriot Y, Sternberg CN, Higano CS, Iversen P, Bhattacharya S, Carles J, Chowdhury S, Davis ID, de Bono JS, Evans CP, et al. Enzalutamide in metastatic prostate cancer before chemotherapy. N Engl J Med. 2014; 371: 424-33. doi: 10.1056/NEJMoa1405095.
-
(2014)
N Engl J Med
, vol.371
, pp. 424-433
-
-
Beer, T.M.1
Armstrong, A.J.2
Rathkopf, D.E.3
Loriot, Y.4
Sternberg, C.N.5
Higano, C.S.6
Iversen, P.7
Bhattacharya, S.8
Carles, J.9
Chowdhury, S.10
Davis, I.D.11
de Bono, J.S.12
Evans, C.P.13
-
24
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher HI, Fizazi K, Saad F, Taplin ME, Sternberg CN, Miller K, de Wit R, Mulders P, Chi KN, Shore ND, Armstrong AJ, Flaig TW, Flechon A, et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med. 2012; 367: 1187-97. doi: 10.1056/NEJMoa1207506.
-
(2012)
N Engl J Med
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
Taplin, M.E.4
Sternberg, C.N.5
Miller, K.6
de Wit, R.7
Mulders, P.8
Chi, K.N.9
Shore, N.D.10
Armstrong, A.J.11
Flaig, T.W.12
Flechon, A.13
-
25
-
-
84994049260
-
Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer
-
Wadosky KM, Koochekpour S. Molecular mechanisms underlying resistance to androgen deprivation therapy in prostate cancer. Oncotarget. 2016;7:64447-64470. doi: 10.18632/oncotarget.10901.
-
(2016)
Oncotarget
, vol.7
, pp. 64447-64470
-
-
Wadosky, K.M.1
Koochekpour, S.2
-
26
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de Wit R, Berry WR, Horti J, Pluzanska A, Chi KN, Oudard S, Theodore C, James ND, Turesson I, Rosenthal MA, Eisenberger MA, Investigators TAX. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med. 2004; 351: 1502-12. doi: 10.1056/NEJMoa040720.
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
de Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
Chi, K.N.6
Oudard, S.7
Theodore, C.8
James, N.D.9
Turesson, I.10
Rosenthal, M.A.11
Eisenberger, M.A.12
Investigators, T.A.X.13
-
27
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tangen CM, Hussain MH, Lara PN, Jr., Jones JA, Taplin ME, Burch PA, Berry D, Moinpour C, Kohli M, Benson MC, Small EJ, Raghavan D, et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med. 2004; 351: 1513-20. doi: 10.1056/NEJMoa041318.
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
Lara, P.N.4
Jones, J.A.5
Taplin, M.E.6
Burch, P.A.7
Berry, D.8
Moinpour, C.9
Kohli, M.10
Benson, M.C.11
Small, E.J.12
Raghavan, D.13
-
28
-
-
38349167518
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study
-
Berthold DR, Pond GR, Soban F, de Wit R, Eisenberger M, Tannock IF. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: updated survival in the TAX 327 study. J Clin Oncol. 2008; 26: 242-5 doi: 10.1200/JCO.2007.12.4008.
-
(2008)
J Clin Oncol
, vol.26
, pp. 242-245
-
-
Berthold, D.R.1
Pond, G.R.2
Soban, F.3
de Wit, R.4
Eisenberger, M.5
Tannock, I.F.6
-
29
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castrationresistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial
-
de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I, Gravis G, Bodrogi I, Mackenzie MJ, Shen L, Roessner M, Gupta S, Sartor AO, et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castrationresistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010; 376: 1147-54. doi: 10.1016/S0140-6736(10)61389-X.
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
de Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
Machiels, J.P.5
Kocak, I.6
Gravis, G.7
Bodrogi, I.8
Mackenzie, M.J.9
Shen, L.10
Roessner, M.11
Gupta, S.12
Sartor, A.O.13
-
30
-
-
77956443521
-
Androgen receptor signaling and mutations in prostate cancer
-
Koochekpour S. Androgen receptor signaling and mutations in prostate cancer. Asian J Androl. 2010; 12: 639-57. doi: 10.1038/aja.2010.89.
-
(2010)
Asian J Androl
, vol.12
, pp. 639-657
-
-
Koochekpour, S.1
-
31
-
-
37349118115
-
Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex
-
Heemers HV, Tindall DJ. Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr Rev. 2007; 28: 778-808. doi: 10.1210/er.2007-0019.
-
(2007)
Endocr Rev
, vol.28
, pp. 778-808
-
-
Heemers, H.V.1
Tindall, D.J.2
-
32
-
-
84880729344
-
Posttranslational modification of the androgen receptor in prostate cancer
-
van der Steen T, Tindall DJ, Huang H. Posttranslational modification of the androgen receptor in prostate cancer. Int J Mol Sci. 2013; 14: 14833-59. doi: 10.3390/ijms140714833.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 14833-14859
-
-
van der Steen, T.1
Tindall, D.J.2
Huang, H.3
-
33
-
-
80054931284
-
Alternatively spliced androgen receptor variants
-
Dehm SM, Tindall DJ. Alternatively spliced androgen receptor variants. Endocr Relat Cancer. 2011; 18: R183-96. doi: 10.1530/ERC-11-0141.
-
(2011)
Endocr Relat Cancer
, vol.18
, pp. R183-R196
-
-
Dehm, S.M.1
Tindall, D.J.2
-
34
-
-
84928997960
-
Androgen receptor variant-7: an important predictive biomarker in castrate resistant prostate cancer
-
Sartor O, Dong Y. Androgen receptor variant-7: an important predictive biomarker in castrate resistant prostate cancer. Asian J Androl. 2015; 17: 439-40. doi: 10.4103/1008-682X.145069.
-
(2015)
Asian J Androl
, vol.17
, pp. 439-440
-
-
Sartor, O.1
Dong, Y.2
-
35
-
-
84991648558
-
Cost-savings analysis of AR-V7 testing in patients with metastatic castration-resistant prostate cancer eligible for treatment with abiraterone or enzalutamide
-
Markowski MC, Frick KD, Eshleman JR, Luo J, Antonarakis ES. Cost-savings analysis of AR-V7 testing in patients with metastatic castration-resistant prostate cancer eligible for treatment with abiraterone or enzalutamide. Prostate. 2016. doi: 10.1002/pros.23232.
-
(2016)
Prostate
-
-
Markowski, M.C.1
Frick, K.D.2
Eshleman, J.R.3
Luo, J.4
Antonarakis, E.S.5
-
36
-
-
84946023365
-
Clinical Relevance of Androgen Receptor Splice Variants in Castration-Resistant Prostate Cancer
-
Maughan BL, Antonarakis ES. Clinical Relevance of Androgen Receptor Splice Variants in Castration-Resistant Prostate Cancer. Curr Treat Options Oncol. 2015; 16: 57. doi: 10.1007/s11864-015-0375-z.
-
(2015)
Curr Treat Options Oncol
, vol.16
, pp. 57
-
-
Maughan, B.L.1
Antonarakis, E.S.2
-
37
-
-
0035199329
-
The putative androgen receptor-A form results from in vitro proteolysis
-
Gregory CW, He B, Wilson EM. The putative androgen receptor-A form results from in vitro proteolysis. J Mol Endocrinol. 2001; 27: 309-19. doi: 10.1677/jme.0.0270309.
-
(2001)
J Mol Endocrinol
, vol.27
, pp. 309-319
-
-
Gregory, C.W.1
He, B.2
Wilson, E.M.3
-
38
-
-
82255175103
-
Androgen receptor and its splice variants in prostate cancer
-
Haile S, Sadar MD. Androgen receptor and its splice variants in prostate cancer. Cell Mol Life Sci. 2011; 68: 3971-81. doi: 10.1007/s00018-011-0766-7.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3971-3981
-
-
Haile, S.1
Sadar, M.D.2
-
39
-
-
84901199317
-
Decoding the androgen receptor splice variants
-
Lu C, Luo J. Decoding the androgen receptor splice variants. Transl Androl Urol. 2013; 2: 178-86. doi: 10.3978/j.issn.2223-4683.2013.09.08.
-
(2013)
Transl Androl Urol
, vol.2
, pp. 178-186
-
-
Lu, C.1
Luo, J.2
-
40
-
-
11444252143
-
Androgen receptor function is modulated by the tissue-specific AR45 variant
-
Ahrens-Fath I, Politz O, Geserick C, Haendler B. Androgen receptor function is modulated by the tissue-specific AR45 variant. FEBS J. 2005; 272: 74-84. doi: 10.1111/j.1742-4658.2004.04395.x.
-
(2005)
FEBS J
, vol.272
, pp. 74-84
-
-
Ahrens-Fath, I.1
Politz, O.2
Geserick, C.3
Haendler, B.4
-
41
-
-
34548057805
-
A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions
-
Jagla M, Feve M, Kessler P, Lapouge G, Erdmann E, Serra S, Bergerat JP, Ceraline J. A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions. Endocrinology. 2007; 148: 4334-43. doi: 10.1210/en.2007-0446.
-
(2007)
Endocrinology
, vol.148
, pp. 4334-4343
-
-
Jagla, M.1
Feve, M.2
Kessler, P.3
Lapouge, G.4
Erdmann, E.5
Serra, S.6
Bergerat, J.P.7
Ceraline, J.8
-
42
-
-
0037262471
-
A yeast-based functional assay for the detection of the mutant androgen receptor in prostate cancer
-
Ceraline J, Erdmann E, Erbs P, Deslandres-Cruchant M, Jacqmin D, Duclos B, Klein-Soyer C, Dufour P, Bergerat JP. A yeast-based functional assay for the detection of the mutant androgen receptor in prostate cancer. Eur J Endocrinol. 2003; 148: 99-110. doi: 10.1530/eje.0.1480099.
-
(2003)
Eur J Endocrinol
, vol.148
, pp. 99-110
-
-
Ceraline, J.1
Erdmann, E.2
Erbs, P.3
Deslandres-Cruchant, M.4
Jacqmin, D.5
Duclos, B.6
Klein-Soyer, C.7
Dufour, P.8
Bergerat, J.P.9
-
43
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res. 2008; 68: 5469-77. doi: 10.1158/0008-5472.CAN-08-0594.
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
44
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormonerefractory prostate cancer
-
Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, Han M, Partin AW, Vessella RL, Isaacs WB, Bova GS, Luo J. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormonerefractory prostate cancer. Cancer Res. 2009; 69: 16-22. doi: 10.1158/0008-5472.CAN-08-2764.
-
(2009)
Cancer Res
, vol.69
, pp. 16-22
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
Isharwal, S.4
Veltri, R.W.5
Humphreys, E.6
Han, M.7
Partin, A.W.8
Vessella, R.L.9
Isaacs, W.B.10
Bova, G.S.11
Luo, J.12
-
45
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, et al. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res. 2009; 69: 2305-13. doi: 10.1158/0008-5472.CAN-08-3795.
-
(2009)
Cancer Res
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
Chen, H.7
Kong, X.8
Melamed, J.9
Tepper, C.G.10
Kung, H.J.11
Brodie, A.M.12
Edwards, J.13
-
46
-
-
84978795460
-
Characterization of fibroblast-free CWRR1ca castration-recurrent prostate cancer cell line
-
Shourideh M, DePriest A, Mohler JL, Wilson EM, Koochekpour S. Characterization of fibroblast-free CWRR1ca castration-recurrent prostate cancer cell line. Prostate. 2016 doi: 10.1002/pros.23190.
-
(2016)
Prostate
-
-
Shourideh, M.1
DePriest, A.2
Mohler, J.L.3
Wilson, E.M.4
Koochekpour, S.5
-
47
-
-
77955296562
-
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
-
Sun S, Sprenger CC, Vessella RL, Haugk K, Soriano K, Mostaghel EA, Page ST, Coleman IM, Nguyen HM, Sun H, Nelson PS, Plymate SR. Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. J Clin Invest. 2010; 120: 2715-30. doi: 10.1172/JCI41824.
-
(2010)
J Clin Invest
, vol.120
, pp. 2715-2730
-
-
Sun, S.1
Sprenger, C.C.2
Vessella, R.L.3
Haugk, K.4
Soriano, K.5
Mostaghel, E.A.6
Page, S.T.7
Coleman, I.M.8
Nguyen, H.M.9
Sun, H.10
Nelson, P.S.11
Plymate, S.R.12
-
48
-
-
84861728843
-
Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal
-
Chan SC, Li Y, Dehm SM. Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal. J Biol Chem. 2012; 287: 19736-49. doi: 10.1074/jbc. M112.352930.
-
(2012)
J Biol Chem
, vol.287
, pp. 19736-19749
-
-
Chan, S.C.1
Li, Y.2
Dehm, S.M.3
-
49
-
-
79959312739
-
A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
-
Hu R, Isaacs WB, Luo J. A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities. Prostate. 2011; 71: 1656-67. doi: 10.1002/pros.21382.
-
(2011)
Prostate
, vol.71
, pp. 1656-1667
-
-
Hu, R.1
Isaacs, W.B.2
Luo, J.3
-
50
-
-
84944474389
-
Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo
-
Kwegyir-Afful AK, Senthilmurugan R, Purushottamachar P, Ramamurthy VP, Njar VC. Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo. Oncotarget. 2015;6:27440-60. doi: 10.18632/oncotarget.4578.
-
(2015)
Oncotarget
, vol.6
, pp. 27440-27460
-
-
Kwegyir-Afful, A.K.1
Senthilmurugan, R.2
Purushottamachar, P.3
Ramamurthy, V.P.4
Njar, V.C.5
-
51
-
-
84904256379
-
Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy
-
Cao B, Qi Y, Zhang G, Xu D, Zhan Y, Alvarez X, Guo Z, Fu X, Plymate SR, Sartor O, Zhang H, Dong Y. Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy. Oncotarget. 2014; 5: 1646-56. doi: 10.18632/oncotarget.1802.
-
(2014)
Oncotarget
, vol.5
, pp. 1646-1656
-
-
Cao, B.1
Qi, Y.2
Zhang, G.3
Xu, D.4
Zhan, Y.5
Alvarez, X.6
Guo, Z.7
Fu, X.8
Plymate, S.R.9
Sartor, O.10
Zhang, H.11
Dong, Y.12
-
52
-
-
84870352810
-
Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival
-
Peacock SO, Fahrenholtz CD, Burnstein KL. Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival. Mol Endocrinol. 2012; 26: 1967-79. doi: 10.1210/me.2012-1165.
-
(2012)
Mol Endocrinol
, vol.26
, pp. 1967-1979
-
-
Peacock, S.O.1
Fahrenholtz, C.D.2
Burnstein, K.L.3
-
53
-
-
78049280194
-
Constitutively active androgen receptor splice variants expressed in castrationresistant prostate cancer require full-length androgen receptor
-
Watson PA, Chen YF, Balbas MD, Wongvipat J, Socci ND, Viale A, Kim K, Sawyers CL. Constitutively active androgen receptor splice variants expressed in castrationresistant prostate cancer require full-length androgen receptor. Proc Natl Acad Sci U S A. 2010; 107: 16759-65. doi: 10.1073/pnas.1012443107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16759-16765
-
-
Watson, P.A.1
Chen, Y.F.2
Balbas, M.D.3
Wongvipat, J.4
Socci, N.D.5
Viale, A.6
Kim, K.7
Sawyers, C.L.8
-
54
-
-
79955719838
-
Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival
-
Hornberg E, Ylitalo EB, Crnalic S, Antti H, Stattin P, Widmark A, Bergh A, Wikstrom P. Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival. PLoS One. 2011; 6: e19059. doi: 10.1371/journal. pone.0019059.
-
(2011)
PLoS One
, vol.6
-
-
Hornberg, E.1
Ylitalo, E.B.2
Crnalic, S.3
Antti, H.4
Stattin, P.5
Widmark, A.6
Bergh, A.7
Wikstrom, P.8
-
55
-
-
0035293021
-
Quantitative analysis of mRNA amplification by in vitro transcription
-
Baugh LR, Hill AA, Brown EL, Hunter CP. Quantitative analysis of mRNA amplification by in vitro transcription. Nucleic Acids Res. 2001; 29: E29. doi: 10.1093/nar/29.5.e29.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. E29
-
-
Baugh, L.R.1
Hill, A.A.2
Brown, E.L.3
Hunter, C.P.4
-
56
-
-
80053923164
-
Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells
-
Yang X, Guo Z, Sun F, Li W, Alfano A, Shimelis H, Chen M, Brodie AM, Chen H, Xiao Z, Veenstra TD, Qiu Y. Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells. J Biol Chem. 2011; 286: 36152-60. doi: 10.1074/jbc. M111.265124.
-
(2011)
J Biol Chem
, vol.286
, pp. 36152-36160
-
-
Yang, X.1
Guo, Z.2
Sun, F.3
Li, W.4
Alfano, A.5
Shimelis, H.6
Chen, M.7
Brodie, A.M.8
Chen, H.9
Xiao, Z.10
Veenstra, T.D.11
Qiu, Y.12
-
57
-
-
84863979005
-
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer
-
Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, Edwards J, Isaacs WB, Nelson PS, Bluemn E, Plymate SR, Luo J. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer Res. 2012; 72: 3457-62. doi: 10.1158/0008-5472.CAN-11-3892.
-
(2012)
Cancer Res
, vol.72
, pp. 3457-3462
-
-
Hu, R.1
Lu, C.2
Mostaghel, E.A.3
Yegnasubramanian, S.4
Gurel, M.5
Tannahill, C.6
Edwards, J.7
Isaacs, W.B.8
Nelson, P.S.9
Bluemn, E.10
Plymate, S.R.11
Luo, J.12
-
58
-
-
84886447413
-
TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer
-
Nyquist MD, Li Y, Hwang TH, Manlove LS, Vessella RL, Silverstein KA, Voytas DF, Dehm SM. TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer. Proc Natl Acad Sci U S A. 2013; 110: 17492-7. doi: 10.1073/pnas.1308587110.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 17492-17497
-
-
Nyquist, M.D.1
Li, Y.2
Hwang, T.H.3
Manlove, L.S.4
Vessella, R.L.5
Silverstein, K.A.6
Voytas, D.F.7
Dehm, S.M.8
-
59
-
-
84942163753
-
Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies
-
Chan SC, Selth LA, Li Y, Nyquist MD, Miao L, Bradner JE, Raj GV, Tilley WD, Dehm SM. Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies. Nucleic Acids Res. 2015; 43: 5880-97. doi: 10.1093/nar/gkv262.
-
(2015)
Nucleic Acids Res
, vol.43
, pp. 5880-5897
-
-
Chan, S.C.1
Selth, L.A.2
Li, Y.3
Nyquist, M.D.4
Miao, L.5
Bradner, J.E.6
Raj, G.V.7
Tilley, W.D.8
Dehm, S.M.9
-
60
-
-
84942860161
-
Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes
-
Xu D, Zhan Y, Qi Y, Cao B, Bai S, Xu W, Gambhir SS, Lee P, Sartor O, Flemington EK, Zhang H, Hu CD, Dong Y. Androgen Receptor Splice Variants Dimerize to Transactivate Target Genes. Cancer Res. 2015; 75: 3663-71 doi: 10.1158/0008-5472.CAN-15-0381.
-
(2015)
Cancer Res
, vol.75
, pp. 3663-3671
-
-
Xu, D.1
Zhan, Y.2
Qi, Y.3
Cao, B.4
Bai, S.5
Xu, W.6
Gambhir, S.S.7
Lee, P.8
Sartor, O.9
Flemington, E.K.10
Zhang, H.11
Hu, C.D.12
Dong, Y.13
-
61
-
-
55049086227
-
The contribution of different androgen receptor domains to receptor dimerization and signaling
-
Centenera MM, Harris JM, Tilley WD, Butler LM. The contribution of different androgen receptor domains to receptor dimerization and signaling. Mol Endocrinol. 2008; 22: 2373-82. doi: 10.1210/me.2008-0017.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 2373-2382
-
-
Centenera, M.M.1
Harris, J.M.2
Tilley, W.D.3
Butler, L.M.4
-
62
-
-
84948464999
-
Preclinical mouse cancer models: a maze of opportunities and challenges
-
Day CP, Merlino G, Van Dyke T. Preclinical mouse cancer models: a maze of opportunities and challenges. Cell. 2015; 163: 39-53. doi: 10.1016/j.cell.2015.08.068.
-
(2015)
Cell
, vol.163
, pp. 39-53
-
-
Day, C.P.1
Merlino, G.2
Van Dyke, T.3
-
63
-
-
10344234761
-
Molecular insights into prostate cancer progression: the missing link of tumor microenvironment
-
Chung LW, Baseman A, Assikis V, Zhau HE. Molecular insights into prostate cancer progression: the missing link of tumor microenvironment. J Urol. 2005; 173: 10-20. doi: 10.1097/01.ju.0000141582.15218.10.
-
(2005)
J Urol
, vol.173
, pp. 10-20
-
-
Chung, L.W.1
Baseman, A.2
Assikis, V.3
Zhau, H.E.4
-
64
-
-
84882788481
-
Current mouse and cell models in prostate cancer research
-
Wu X, Gong S, Roy-Burman P, Lee P, Culig Z. Current mouse and cell models in prostate cancer research. Endocr Relat Cancer. 2013; 20: R155-70. doi: 10.1530/ERC-12-0285.
-
(2013)
Endocr Relat Cancer
, vol.20
, pp. R155-R170
-
-
Wu, X.1
Gong, S.2
Roy-Burman, P.3
Lee, P.4
Culig, Z.5
-
65
-
-
84904663703
-
Castration induces up-regulation of intratumoral androgen biosynthesis and androgen receptor expression in an orthotopic VCaP human prostate cancer xenograft model
-
Knuuttila M, Yatkin E, Kallio J, Savolainen S, Laajala TD, Aittokallio T, Oksala R, Hakkinen M, Keski-Rahkonen P, Auriola S, Poutanen M, Makela S. Castration induces up-regulation of intratumoral androgen biosynthesis and androgen receptor expression in an orthotopic VCaP human prostate cancer xenograft model. Am J Pathol. 2014; 184: 2163-73. doi: 10.1016/j.ajpath.2014.04.010.
-
(2014)
Am J Pathol
, vol.184
, pp. 2163-2173
-
-
Knuuttila, M.1
Yatkin, E.2
Kallio, J.3
Savolainen, S.4
Laajala, T.D.5
Aittokallio, T.6
Oksala, R.7
Hakkinen, M.8
Keski-Rahkonen, P.9
Auriola, S.10
Poutanen, M.11
Makela, S.12
-
66
-
-
34547850622
-
In vivo MRI volumetric measurement of prostate regression and growth in mice
-
Nastiuk KL, Liu H, Hamamura M, Muftuler LT, Nalcioglu O, Krolewski JJ. In vivo MRI volumetric measurement of prostate regression and growth in mice. BMC Urol. 2007; 7: 12. doi: 10.1186/1471-2490-7-12.
-
(2007)
BMC Urol
, vol.7
, pp. 12
-
-
Nastiuk, K.L.1
Liu, H.2
Hamamura, M.3
Muftuler, L.T.4
Nalcioglu, O.5
Krolewski, J.J.6
-
67
-
-
84896536370
-
Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer
-
Yu Z, Chen S, Sowalsky AG, Voznesensky OS, Mostaghel EA, Nelson PS, Cai C, Balk SP. Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer. Clin Cancer Res. 2014; 20: 1590-600. doi: 10.1158/1078-0432.CCR-13-1863.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1590-1600
-
-
Yu, Z.1
Chen, S.2
Sowalsky, A.G.3
Voznesensky, O.S.4
Mostaghel, E.A.5
Nelson, P.S.6
Cai, C.7
Balk, S.P.8
-
68
-
-
68049131467
-
Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer
-
Cai C, Wang H, Xu Y, Chen S, Balk SP. Reactivation of androgen receptor-regulated TMPRSS2:ERG gene expression in castration-resistant prostate cancer. Cancer Res. 2009; 69: 6027-32. doi: 10.1158/0008-5472.CAN-09-0395.
-
(2009)
Cancer Res
, vol.69
, pp. 6027-6032
-
-
Cai, C.1
Wang, H.2
Xu, Y.3
Chen, S.4
Balk, S.P.5
-
69
-
-
84979519295
-
Intratumoral and Intertumoral Genomic Heterogeneity of Multifocal Localized Prostate Cancer Impacts Molecular Classifications and Genomic Prognosticators
-
Wei L, Wang J, Lampert E, Schlanger S, DePriest AD, Hu Q, Gomez EC, Murakam M, Glenn ST, Conroy J, Morrison C, Azabdaftari G, Mohler JL, et al. Intratumoral and Intertumoral Genomic Heterogeneity of Multifocal Localized Prostate Cancer Impacts Molecular Classifications and Genomic Prognosticators. Eur Urol. 2016 doi: 10.1016/j.eururo.2016.07.008.
-
(2016)
Eur Urol
-
-
Wei, L.1
Wang, J.2
Lampert, E.3
Schlanger, S.4
DePriest, A.D.5
Hu, Q.6
Gomez, E.C.7
Murakam, M.8
Glenn, S.T.9
Conroy, J.10
Morrison, C.11
Azabdaftari, G.12
Mohler, J.L.13
-
70
-
-
0029938570
-
Characterization of a novel androgen-sensitive, prostate-specific antigen-producing prostatic carcinoma xenograft: LuCaP 23
-
Ellis WJ, Vessella RL, Buhler KR, Bladou F, True LD, Bigler SA, Curtis D, Lange PH. Characterization of a novel androgen-sensitive, prostate-specific antigen-producing prostatic carcinoma xenograft: LuCaP 23. Clin Cancer Res. 1996; 2: 1039-48. doi:
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1039-1048
-
-
Ellis, W.J.1
Vessella, R.L.2
Buhler, K.R.3
Bladou, F.4
True, L.D.5
Bigler, S.A.6
Curtis, D.7
Lange, P.H.8
-
71
-
-
0038475987
-
LuCaP 35: a new model of prostate cancer progression to androgen independence
-
Corey E, Quinn JE, Buhler KR, Nelson PS, Macoska JA, True LD, Vessella RL. LuCaP 35: a new model of prostate cancer progression to androgen independence. Prostate. 2003; 55: 239-46. doi: 10.1002/pros.10198.
-
(2003)
Prostate
, vol.55
, pp. 239-246
-
-
Corey, E.1
Quinn, J.E.2
Buhler, K.R.3
Nelson, P.S.4
Macoska, J.A.5
True, L.D.6
Vessella, R.L.7
-
72
-
-
84920733767
-
Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: results from a pilot clinical study
-
Schweizer MT, Antonarakis ES, Wang H, Ajiboye AS, Spitz A, Cao H, Luo J, Haffner MC, Yegnasubramanian S, Carducci MA, Eisenberger MA, Isaacs JT, Denmeade SR. Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: results from a pilot clinical study. Sci Transl Med. 2015; 7: 269ra2. doi: 10.1126/scitranslmed.3010563.
-
(2015)
Sci Transl Med
, vol.7
-
-
Schweizer, M.T.1
Antonarakis, E.S.2
Wang, H.3
Ajiboye, A.S.4
Spitz, A.5
Cao, H.6
Luo, J.7
Haffner, M.C.8
Yegnasubramanian, S.9
Carducci, M.A.10
Eisenberger, M.A.11
Isaacs, J.T.12
Denmeade, S.R.13
-
73
-
-
80052827038
-
Resistance to CYP17A1 inhibition with abiraterone in castrationresistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants
-
Mostaghel EA, Marck BT, Plymate SR, Vessella RL, Balk S, Matsumoto AM, Nelson PS, Montgomery RB. Resistance to CYP17A1 inhibition with abiraterone in castrationresistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants. Clin Cancer Res. 2011; 17: 5913-25. doi: 10.1158/1078-0432.CCR-11-0728.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5913-5925
-
-
Mostaghel, E.A.1
Marck, B.T.2
Plymate, S.R.3
Vessella, R.L.4
Balk, S.5
Matsumoto, A.M.6
Nelson, P.S.7
Montgomery, R.B.8
-
74
-
-
0028012612
-
The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice
-
Greenberg NM, DeMayo FJ, Sheppard PC, Barrios R, Lebovitz R, Finegold M, Angelopoulou R, Dodd JG, Duckworth ML, Rosen JM, et al. The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice. Mol Endocrinol. 1994; 8: 230-9 doi: 10.1210/mend.8.2.8170479.
-
(1994)
Mol Endocrinol
, vol.8
, pp. 230-239
-
-
Greenberg, N.M.1
DeMayo, F.J.2
Sheppard, P.C.3
Barrios, R.4
Lebovitz, R.5
Finegold, M.6
Angelopoulou, R.7
Dodd, J.G.8
Duckworth, M.L.9
Rosen, J.M.10
-
75
-
-
84884377857
-
AR variant ARv567es induces carcinogenesis in a novel transgenic mouse model of prostate cancer
-
Liu G, Sprenger C, Sun S, Epilepsia KS, Haugk K, Zhang X, Coleman I, Nelson PS, Plymate S. AR variant ARv567es induces carcinogenesis in a novel transgenic mouse model of prostate cancer. Neoplasia. 2013; 15: 1009-17. doi: 10.1593/neo.13784.
-
(2013)
Neoplasia
, vol.15
, pp. 1009-1017
-
-
Liu, G.1
Sprenger, C.2
Sun, S.3
Epilepsia, K.S.4
Haugk, K.5
Zhang, X.6
Coleman, I.7
Nelson, P.S.8
Plymate, S.9
-
76
-
-
84892645101
-
Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors
-
Sun F, Chen HG, Li W, Yang X, Wang X, Jiang R, Guo Z, Chen H, Huang J, Borowsky AD, Qiu Y. Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors. J Biol Chem. 2014; 289: 1529-39. doi: 10.1074/jbc. M113.492140.
-
(2014)
J Biol Chem
, vol.289
, pp. 1529-1539
-
-
Sun, F.1
Chen, H.G.2
Li, W.3
Yang, X.4
Wang, X.5
Jiang, R.6
Guo, Z.7
Chen, H.8
Huang, J.9
Borowsky, A.D.10
Qiu, Y.11
-
77
-
-
84905088552
-
Mouse models of prostate cancer: picking the best model for the question
-
Grabowska MM, DeGraffDJ, Yu X, Jin RJ, Chen Z, Borowsky AD, Matusik RJ. Mouse models of prostate cancer: picking the best model for the question. Cancer Metastasis Rev. 2014; 33: 377-97. doi: 10.1007/s10555-013-9487-8.
-
(2014)
Cancer Metastasis Rev
, vol.33
, pp. 377-397
-
-
Grabowska, M.M.1
DeGraff, D.J.2
Yu, X.3
Jin, R.J.4
Chen, Z.5
Borowsky, A.D.6
Matusik, R.J.7
-
78
-
-
84901008773
-
The many faces of neuroendocrine differentiation in prostate cancer progression
-
Terry S, Beltran H. The many faces of neuroendocrine differentiation in prostate cancer progression. Front Oncol. 2014; 4: 60. doi: 10.3389/fonc.2014.00060.
-
(2014)
Front Oncol
, vol.4
, pp. 60
-
-
Terry, S.1
Beltran, H.2
-
79
-
-
84926160408
-
Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer
-
Efstathiou E, Titus M, Wen S, Hoang A, Karlou M, Ashe R, Tu SM, Aparicio A, Troncoso P, Mohler J, Logothetis CJ. Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer. Eur Urol. 2015; 67: 53-60. doi: 10.1016/j.eururo.2014.05.005.
-
(2015)
Eur Urol
, vol.67
, pp. 53-60
-
-
Efstathiou, E.1
Titus, M.2
Wen, S.3
Hoang, A.4
Karlou, M.5
Ashe, R.6
Tu, S.M.7
Aparicio, A.8
Troncoso, P.9
Mohler, J.10
Logothetis, C.J.11
-
80
-
-
66249135684
-
Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy
-
Steinkamp MP, O'Mahony OA, Brogley M, Rehman H, Lapensee EW, Dhanasekaran S, Hofer MD, Kuefer R, Chinnaiyan A, Rubin MA, Pienta KJ, Robins DM. Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy. Cancer Res. 2009; 69: 4434-42. doi: 10.1158/0008-5472.CAN-08-3605.
-
(2009)
Cancer Res
, vol.69
, pp. 4434-4442
-
-
Steinkamp, M.P.1
O'Mahony, O.A.2
Brogley, M.3
Rehman, H.4
Lapensee, E.W.5
Dhanasekaran, S.6
Hofer, M.D.7
Kuefer, R.8
Chinnaiyan, A.9
Rubin, M.A.10
Pienta, K.J.11
Robins, D.M.12
-
81
-
-
84930225081
-
Integrative clinical genomics of advanced prostate cancer
-
Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, et al. Integrative clinical genomics of advanced prostate cancer. Cell. 2015; 161: 1215-28. doi: 10.1016/j.cell.2015.05.001.
-
(2015)
Cell
, vol.161
, pp. 1215-1228
-
-
Robinson, D.1
Van Allen, E.M.2
Wu, Y.M.3
Schultz, N.4
Lonigro, R.J.5
Mosquera, J.M.6
Montgomery, B.7
Taplin, M.E.8
Pritchard, C.C.9
Attard, G.10
Beltran, H.11
Abida, W.12
Bradley, R.K.13
-
82
-
-
84907057471
-
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer
-
Antonarakis ES, Lu C, Wang H, Luber B, Nakazawa M, Roeser JC, Chen Y, Mohammad TA, Chen Y, Fedor HL, Lotan TL, Zheng Q, De Marzo AM, et al. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. N Engl J Med. 2014; 371: 1028-38. doi: 10.1056/NEJMoa1315815.
-
(2014)
N Engl J Med
, vol.371
, pp. 1028-1038
-
-
Antonarakis, E.S.1
Lu, C.2
Wang, H.3
Luber, B.4
Nakazawa, M.5
Roeser, J.C.6
Chen, Y.7
Mohammad, T.A.8
Chen, Y.9
Fedor, H.L.10
Lotan, T.L.11
Zheng, Q.12
De Marzo, A.M.13
-
83
-
-
84991821829
-
Technical challenges in the isolation and analysis of circulating tumor cells
-
van der Toom EE, Verdone JE, Gorin MA, Pienta KJ. Technical challenges in the isolation and analysis of circulating tumor cells. Oncotarget. 2016;7:62754-62766. doi: 10.18632/oncotarget.11191.
-
(2016)
Oncotarget
, vol.7
, pp. 62754-62766
-
-
van der Toom, E.E.1
Verdone, J.E.2
Gorin, M.A.3
Pienta, K.J.4
-
84
-
-
85068160367
-
Detecting predictive androgen receptor modifications in circulating prostate cancer cells
-
Steinestel J, Luedeke M, Arndt A, Schnoeller TJ, Lennerz JK, Wurm C, Maier C, Cronauer MV, Steinestel K, Schrader AJ. Detecting predictive androgen receptor modifications in circulating prostate cancer cells. Oncotarget. 2015. doi: 10.18632/oncotarget.3925.
-
(2015)
Oncotarget
-
-
Steinestel, J.1
Luedeke, M.2
Arndt, A.3
Schnoeller, T.J.4
Lennerz, J.K.5
Wurm, C.6
Maier, C.7
Cronauer, M.V.8
Steinestel, K.9
Schrader, A.J.10
-
85
-
-
84995902323
-
A Whole Blood Assay for AR-V7 and ARv567es in Prostate Cancer Patients
-
Liu X, Ledet E, Li D, Dotiwala A, Steinberger A, Feibus A, Li J, Qi Y, Silberstein J, Lee B, Dong Y, Sartor O, Zhang H. A Whole Blood Assay for AR-V7 and ARv567es in Prostate Cancer Patients. J Urol. 2016. doi: 10.1016/j. juro.2016.06.095.
-
(2016)
J Urol
-
-
Liu, X.1
Ledet, E.2
Li, D.3
Dotiwala, A.4
Steinberger, A.5
Feibus, A.6
Li, J.7
Qi, Y.8
Silberstein, J.9
Lee, B.10
Dong, Y.11
Sartor, O.12
Zhang, H.13
-
86
-
-
85003583757
-
AR-V7 transcripts in whole blood RNA of patients with metastatic castration resistant prostate cancer correlate with response to Abiraterone acetate
-
Todenhofer T, Azad A, Stewart C, Gao J, Eigl BJ, Gleave ME, Joshua AM, Black PC, Chi KN. AR-V7 transcripts in whole blood RNA of patients with metastatic castration resistant prostate cancer correlate with response to Abiraterone acetate. J Urol. 2016. doi: 10.1016/j. juro.2016.06.094.
-
(2016)
J Urol
-
-
Todenhofer, T.1
Azad, A.2
Stewart, C.3
Gao, J.4
Eigl, B.J.5
Gleave, M.E.6
Joshua, A.M.7
Black, P.C.8
Chi, K.N.9
-
87
-
-
85012293401
-
Association of AR-V7 and prostate specific antigen RNA levels in blood with efficacy of abiraterone acetate and enzalutamide treatment in men with prostate cancer
-
Qu F, Xie W, Nakabayashi M, Zhang H, Jeong SH, Wang X, Komura K, Sweeney CJ, Sartor O, Lee GM, KantoffPW. Association of AR-V7 and prostate specific antigen RNA levels in blood with efficacy of abiraterone acetate and enzalutamide treatment in men with prostate cancer. Clin Cancer Res. 2016. doi: 10.1158/1078-0432.CCR-16-1070.
-
(2016)
Clin Cancer Res
-
-
Qu, F.1
Xie, W.2
Nakabayashi, M.3
Zhang, H.4
Jeong, S.H.5
Wang, X.6
Komura, K.7
Sweeney, C.J.8
Sartor, O.9
Lee, G.M.10
Kantoff, P.W.11
-
88
-
-
84943657622
-
Digital PCR analysis of circulating nucleic acids
-
Hudecova I. Digital PCR analysis of circulating nucleic acids. Clin Biochem. 2015; 48: 948-56. doi: 10.1016/j. clinbiochem.2015.03.015.
-
(2015)
Clin Biochem
, vol.48
, pp. 948-956
-
-
Hudecova, I.1
-
89
-
-
84979711034
-
Expression of AR-V7 in Circulating Tumour Cells Does Not Preclude Response to Next Generation Androgen Deprivation Therapy in Patients with Castration Resistant Prostate Cancer
-
Bernemann C, Schnoeller TJ, Luedeke M, Steinestel K, Boegemann M, Schrader AJ, Steinestel J. Expression of AR-V7 in Circulating Tumour Cells Does Not Preclude Response to Next Generation Androgen Deprivation Therapy in Patients with Castration Resistant Prostate Cancer. Eur Urol. 2016. doi: 10.1016/j.eururo.2016.07.021.
-
(2016)
Eur Urol
-
-
Bernemann, C.1
Schnoeller, T.J.2
Luedeke, M.3
Steinestel, K.4
Boegemann, M.5
Schrader, A.J.6
Steinestel, J.7
-
90
-
-
85006746979
-
Targeting the N-Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer
-
Antonarakis ES, Chandhasin C, Osbourne E, Luo J, Sadar MD, Perabo F. Targeting the N-Terminal Domain of the Androgen Receptor: A New Approach for the Treatment of Advanced Prostate Cancer. Oncologist. 2016. doi: 10.1634/theoncologist.2016-0161.
-
(2016)
Oncologist
-
-
Antonarakis, E.S.1
Chandhasin, C.2
Osbourne, E.3
Luo, J.4
Sadar, M.D.5
Perabo, F.6
-
91
-
-
77953280591
-
Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the aminoterminus domain of the androgen receptor
-
Andersen RJ, Mawji NR, Wang J, Wang G, Haile S, Myung JK, Watt K, Tam T, Yang YC, Banuelos CA, Williams DE, McEwan IJ, Wang Y, et al. Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the aminoterminus domain of the androgen receptor. Cancer Cell. 2010; 17: 535-46. doi: 10.1016/j.ccr.2010.04.027.
-
(2010)
Cancer Cell
, vol.17
, pp. 535-546
-
-
Andersen, R.J.1
Mawji, N.R.2
Wang, J.3
Wang, G.4
Haile, S.5
Myung, J.K.6
Watt, K.7
Tam, T.8
Yang, Y.C.9
Banuelos, C.A.10
Williams, D.E.11
McEwan, I.J.12
Wang, Y.13
-
92
-
-
84879628727
-
An androgen receptor N-terminal domain antagonist for treating prostate cancer
-
Myung JK, Banuelos CA, Fernandez JG, Mawji NR, Wang J, Tien AH, Yang YC, Tavakoli I, Haile S, Watt K, McEwan IJ, Plymate S, Andersen RJ, et al. An androgen receptor N-terminal domain antagonist for treating prostate cancer. J Clin Invest. 2013; 123: 2948-60. doi: 10.1172/JCI66398.
-
(2013)
J Clin Invest
, vol.123
, pp. 2948-2960
-
-
Myung, J.K.1
Banuelos, C.A.2
Fernandez, J.G.3
Mawji, N.R.4
Wang, J.5
Tien, A.H.6
Yang, Y.C.7
Tavakoli, I.8
Haile, S.9
Watt, K.10
McEwan, I.J.11
Plymate, S.12
Andersen, R.J.13
-
93
-
-
84902679103
-
Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer
-
Liu C, Lou W, Zhu Y, Nadiminty N, Schwartz CT, Evans CP, Gao AC. Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer. Clin Cancer Res. 2014; 20: 3198-210. doi: 10.1158/1078-0432.CCR-13-3296.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 3198-3210
-
-
Liu, C.1
Lou, W.2
Zhu, Y.3
Nadiminty, N.4
Schwartz, C.T.5
Evans, C.P.6
Gao, A.C.7
-
94
-
-
84973572847
-
Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer
-
Liu C, Armstrong C, Zhu Y, Lou W, Gao AC. Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer. Oncotarget. 2016;7:32210-20. doi: 10.18632/oncotarget.8493.
-
(2016)
Oncotarget
, vol.7
, pp. 32210-32220
-
-
Liu, C.1
Armstrong, C.2
Zhu, Y.3
Lou, W.4
Gao, A.C.5
-
95
-
-
84923868863
-
Discovery and development of Galeterone (TOK-001 or VN/124-1) for the treatment of all stages of prostate cancer
-
Njar VC, Brodie AM. Discovery and development of Galeterone (TOK-001 or VN/124-1) for the treatment of all stages of prostate cancer. J Med Chem. 2015; 58: 2077-87. doi: 10.1021/jm501239f.
-
(2015)
J Med Chem
, vol.58
, pp. 2077-2087
-
-
Njar, V.C.1
Brodie, A.M.2
-
96
-
-
20944449560
-
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model
-
Handratta VD, Vasaitis TS, Njar VC, Gediya LK, Kataria R, Chopra P, Newman D, Jr., Farquhar R, Guo Z, Qiu Y, Brodie AM. Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model. J Med Chem. 2005; 48: 2972-84. doi: 10.1021/jm040202w.
-
(2005)
J Med Chem
, vol.48
, pp. 2972-2984
-
-
Handratta, V.D.1
Vasaitis, T.S.2
Njar, V.C.3
Gediya, L.K.4
Kataria, R.5
Chopra, P.6
Newman, D.7
Farquhar, R.8
Guo, Z.9
Qiu, Y.10
Brodie, A.M.11
-
97
-
-
84905436109
-
Galeterone prevents androgen receptor binding to chromatin and enhances degradation of mutant androgen receptor
-
Yu Z, Cai C, Gao S, Simon NI, Shen HC, Balk SP. Galeterone prevents androgen receptor binding to chromatin and enhances degradation of mutant androgen receptor. Clin Cancer Res. 2014; 20: 4075-85. doi: 10.1158/1078-0432. CCR-14-0292.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 4075-4085
-
-
Yu, Z.1
Cai, C.2
Gao, S.3
Simon, N.I.4
Shen, H.C.5
Balk, S.P.6
|