메뉴 건너뛰기




Volumn 69, Issue 10, 2009, Pages 4434-4442

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; BICALUTAMIDE; FLUTAMIDE;

EID: 66249135684     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-3605     Document Type: Article
Times cited : (177)

References (48)
  • 2
    • 45549102966 scopus 로고    scopus 로고
    • Cancers exhibit a mutator phenotype: Clinical implications
    • discussion 7
    • Loeb LA, Bielas JH, Beckman RA. Cancers exhibit a mutator phenotype: clinical implications. Cancer Res 2008;68:3551-7; discussion 7.
    • (2008) Cancer Res , vol.68 , pp. 3551-3557
    • Loeb, L.A.1    Bielas, J.H.2    Beckman, R.A.3
  • 3
    • 0021072579 scopus 로고
    • New approach in the treatment of prostate cancer: Complete instead of partial withdrawal of androgens
    • Labrie F, Dupont A, Belanger A, et al. New approach in the treatment of prostate cancer: complete instead of partial withdrawal of androgens. Prostate 1983;4:579-594 (Pubitemid 14243323)
    • (1983) Prostate , vol.4 , Issue.6 , pp. 579-594
    • Labrie, F.1    Dupont, A.2    Belanger, A.3
  • 4
    • 33645690200 scopus 로고    scopus 로고
    • Mechanisms underlying the development of androgen-independent prostate cancer
    • Pienta KJ, Bradley D. Mechanisms underlying the development of androgen-independent prostate cancer. Clin Cancer Res 2006;12:1665-1671
    • (2006) Clin Cancer Res , vol.12 , pp. 1665-1671
    • Pienta, K.J.1    Bradley, D.2
  • 5
    • 4944246790 scopus 로고    scopus 로고
    • Targeting the androgen receptor: Improving outcomes for castration-resistant prostate cancer
    • DOI 10.1677/erc.1.00525
    • Scher HI, Buchanan G, Gerald W, Butler LM, Tilley WD. Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer. Endocr Relat Cancer 2004;11:459-476 (Pubitemid 39331277)
    • (2004) Endocrine-Related Cancer , vol.11 , Issue.3 , pp. 459-476
    • Scher, H.I.1    Buchanan, G.2    Gerald, W.3    Butler, L.M.4    Tilley, W.D.5
  • 6
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001;1:34-45. (Pubitemid 33741879)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 8
    • 0027203411 scopus 로고
    • Flutamide withdrawal syndrome: Its impact on clinical trials in hormone- Refractory prostate cancer
    • Scher HI, Kelly WK. Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer. J Clin Oncol 1993;11:1566-1572 (Pubitemid 23228264)
    • (1993) Journal of Clinical Oncology , vol.11 , Issue.8 , pp. 1566-1572
    • Scher, H.I.1    Kelly, W.K.2
  • 9
    • 48849085967 scopus 로고    scopus 로고
    • Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade
    • Suzuki H, Okihara K, Miyake H, et al. Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade. J Urol 2008;180:921-927
    • (2008) J Urol , vol.180 , pp. 921-927
    • Suzuki, H.1    Okihara, K.2    Miyake, H.3
  • 11
    • 18644372239 scopus 로고    scopus 로고
    • Androgen receptor mutants detected in recurrent prostate cancer exhibit diverse functional characteristics
    • DOI 10.1002/pros.20191
    • Chen G, Wang X, Zhang S, et al. Androgen receptor mutants detected in recurrent prostate cancer exhibit diverse functional characteristics. Prostate 2005;63:395-406. (Pubitemid 40664351)
    • (2005) Prostate , vol.63 , Issue.4 , pp. 395-406
    • Chen, G.1    Wang, X.2    Zhang, S.3    Lu, Y.4    Sun, Y.5    Zhang, J.6    Li, Z.7    Lu, J.8
  • 13
    • 0029915052 scopus 로고    scopus 로고
    • Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence
    • Tilley WD, Buchanan G, Hickey TE, Bentel JM. Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence. Clin Cancer Res 1996;2:277-285 (Pubitemid 26074615)
    • (1996) Clinical Cancer Research , vol.2 , Issue.2 , pp. 277-285
    • Tilley, W.D.1    Buchanan, G.2    Hickey, T.E.3    Bentel, J.M.4
  • 15
    • 2642544224 scopus 로고    scopus 로고
    • The androgen receptor gene mutations database (ARDB): 2004 update
    • Gottlieb B, Beitel LK, Wu JH, Trifiro M. The androgen receptor gene mutations database (ARDB): 2004 update. Hum Mutat 2004;23:527-533
    • (2004) Hum Mutat , vol.23 , pp. 527-533
    • Gottlieb, B.1    Beitel, L.K.2    Wu, J.H.3    Trifiro, M.4
  • 16
    • 0035815749 scopus 로고    scopus 로고
    • Hormone Status Selects for Spontaneous Somatic Androgen Receptor Variants That Demonstrate Specific Ligand and Cofactor Dependent Activities in Autochthonous Prostate Cancer
    • DOI 10.1074/jbc.M008207200
    • Han G, Foster BA, Mistry S, et al. Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer. J Biol Chem 2001;276:11204-11213 (Pubitemid 38089305)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.14 , pp. 11204-11213
    • Han, G.1    Foster, B.A.2    Mistry, S.3    Buchanan, G.4    Harris, J.M.5    Tilley, W.D.6    Greenberg, N.M.7
  • 17
    • 56449126966 scopus 로고    scopus 로고
    • Profiling human androgen receptor mutations reveals treatment effects in a mouse model of prostate cancer
    • O'Mahony OA, Steinkamp MP, Albertelli MA, Brogley M, Rehman M, Robins D. Profiling human androgen receptor mutations reveals treatment effects in a mouse model of prostate cancer. Mol Cancer Res 2008;6:1691-1701
    • (2008) Mol Cancer Res , vol.6 , pp. 1691-1701
    • O'Mahony, O.A.1    Steinkamp, M.P.2    Albertelli, M.A.3    Brogley, M.4    Rehman, M.5    Robins, D.6
  • 20
    • 0034465490 scopus 로고    scopus 로고
    • Human androgen receptor mutation disrupts ternary interactions between ligand, receptor domains, and the coactivator TIF2 (transcription intermediary factor 2)
    • Lim J, Ghadessy FJ, Abdullah AA, Pinsky L, Trifiro M, Yong EL. Human androgen receptor mutation disrupts ternary interactions between ligand, receptor domains, and the coactivator TIF2 (transcription intermediary factor 2). Mol Endocrinol 2000;14:1187-1197
    • (2000) Mol Endocrinol , vol.14 , pp. 1187-1197
    • Lim, J.1    Ghadessy, F.J.2    Abdullah, A.A.3    Pinsky, L.4    Trifiro, M.5    Yong, E.L.6
  • 21
    • 0343714601 scopus 로고    scopus 로고
    • A role for GATA transcription factors in the androgen regulation of the prostate-specific antigen gene enhancer
    • Perez-Stable CM, Pozas A, Roos BA. A role for GATA transcription factors in the androgen regulation of the prostate-specific antigen gene enhancer. Mol Cell Endocrinol 2000;167:43-53.
    • (2000) Mol Cell Endocrinol , vol.167 , pp. 43-53
    • Perez-Stable, C.M.1    Pozas, A.2    Roos, B.A.3
  • 22
    • 27244432574 scopus 로고    scopus 로고
    • Androgen receptor and molecular mechanisms of male-specific gene expression
    • discussion 3-6, 96-99
    • Robins DM. Androgen receptor and molecular mechanisms of male-specific gene expression. Novartis Found Symp 2005;268:42-52; discussion 3-6, 96-99
    • (2005) Novartis Found Symp , vol.268 , pp. 42-52
    • Robins, D.M.1
  • 23
    • 0034623225 scopus 로고    scopus 로고
    • An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways
    • Inohara N, Koseki T, Lin J, et al. An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways. J Biol Chem 2000;275:27823-27831
    • (2000) J Biol Chem , vol.275 , pp. 27823-27831
    • Inohara, N.1    Koseki, T.2    Lin, J.3
  • 24
    • 33845443896 scopus 로고    scopus 로고
    • Escherichia coli DNA polymerase III epsilon subunit increases Moloney murine leukemia virus reverse transcriptase fidelity and accuracy of RT-PCR procedures
    • Arezi B, Hogrefe HH. Escherichia coli DNA polymerase III epsilon subunit increases Moloney murine leukemia virus reverse transcriptase fidelity and accuracy of RT-PCR procedures. Anal Biochem 2007;360:84-91.
    • (2007) Anal Biochem , vol.360 , pp. 84-91
    • Arezi, B.1    Hogrefe, H.H.2
  • 25
    • 2942549111 scopus 로고    scopus 로고
    • A SNP-centric database for the investigation of the human genome
    • DOI 10.1186/1471-2105-5-33
    • Riva A, Kohane IS. A SNP-centric database for the investigation of the human genome. BMC Bioinformatics 2004;5:33. (Pubitemid 38751302)
    • (2004) BMC Bioinformatics , vol.5 , pp. 33
    • Riva, A.1    Kohane, I.S.2
  • 27
    • 33745210533 scopus 로고    scopus 로고
    • The E3 ubiquitin ligase CHIP binds the androgen receptor in a phosphorylation-dependent manner
    • DOI 10.1016/j.bbapap.2006.03.013, PII S157096390600121X
    • Rees I, Lee S, Kim H, Tsai FT. The E3 ubiquitin ligase CHIP binds the androgen receptor in a phosphorylation-dependent manner. Biochim Biophys Acta 2006;1764:1073-1079 (Pubitemid 43912535)
    • (2006) Biochimica et Biophysica Acta - Proteins and Proteomics , vol.1764 , Issue.6 , pp. 1073-1079
    • Rees, I.1    Lee, S.2    Kim, H.3    Tsai, F.T.F.4
  • 28
    • 0025644325 scopus 로고
    • A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens
    • Veldscholte J, Ris-Stalpers C, Kuiper GG, et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem Biophys Res Commun 1990;173:534-540
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 534-540
    • Veldscholte, J.1    Ris-Stalpers, C.2    Kuiper, G.G.3
  • 31
    • 34548057805 scopus 로고    scopus 로고
    • A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions
    • DOI 10.1210/en.2007-0446
    • Jagla M, Feve M, Kessler P, et al. A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions. Endocrinology 2007;148:4334-4343 (Pubitemid 47295699)
    • (2007) Endocrinology , vol.148 , Issue.9 , pp. 4334-4343
    • Jagla, M.1    Feve, M.2    Kessler, P.3    Lapouge, G.4    Erdmann, E.5    Serra, S.6    Bergerat, J.-P.7    Ceraline, J.8
  • 33
    • 27744445735 scopus 로고    scopus 로고
    • The androgen receptor: Unlocking the secrets of its unique transactivation domain
    • Shen HC, Coetzee GA. The androgen receptor: unlocking the secrets of its unique transactivation domain. Vitam Horm 2005;71:301-319
    • (2005) Vitam Horm , vol.71 , pp. 301-319
    • Shen, H.C.1    Coetzee, G.A.2
  • 34
    • 0033978514 scopus 로고    scopus 로고
    • Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamine length
    • Irvine RA, Ma H, Yu MC, Ross RK, Stallcup MR, Coetzee GA. Inhibition of p160-mediated coactivation with increasing androgen receptor polyglutamine length. Hum Mol Genet 2000;9:267-274 (Pubitemid 30052750)
    • (2000) Human Molecular Genetics , vol.9 , Issue.2 , pp. 267-274
    • Irvine, R.A.1    Ma, H.2    Yu, M.C.3    Ross, R.K.4    Stallcup, M.R.5    Coetzee, G.A.6
  • 36
    • 16644396665 scopus 로고    scopus 로고
    • Multiple Mechanisms of Male-Specific Gene Expression: Lessons from the Mouse Sex-Limited Protein (Slp) Gene
    • DOI 10.1016/S0079-6603(04)78001-0, PII S0079660304780010
    • Robins DM. Multiple mechanisms of male-specific gene expression: lessons from the mouse sex-limited protein (Slp) gene. Prog Nucleic Acid Res Mol Biol 2004;78:1-36. (Pubitemid 39752477)
    • (2004) Progress in Nucleic Acid Research and Molecular Biology , vol.78 , pp. 1-36
    • Robins, D.M.1
  • 38
    • 0037184121 scopus 로고    scopus 로고
    • Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells
    • Lin HK, Altuwaijri S, Lin WJ, Kan PY, Collins LL, Chang C. Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells. J Biol Chem 2002;277:36570-36576
    • (2002) J Biol Chem , vol.277 , pp. 36570-36576
    • Lin, H.K.1    Altuwaijri, S.2    Lin, W.J.3    Kan, P.Y.4    Collins, L.L.5    Chang, C.6
  • 40
    • 27844611242 scopus 로고    scopus 로고
    • Structural basis for accommodation of nonsteroidal ligands in the androgen receptor
    • DOI 10.1074/jbc.M507464200
    • Bohl CE, Miller DD, Chen J, Bell CE, Dalton JT. Structural basis for accommodation of nonsteroidal ligands in the androgen receptor. J Biol Chem 2005;280:37747-37754 (Pubitemid 41642384)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.45 , pp. 37747-37754
    • Bohl, C.E.1    Miller, D.D.2    Chen, J.3    Bell, C.E.4    Dalton, J.T.5
  • 41
    • 27544485276 scopus 로고    scopus 로고
    • Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient
    • DOI 10.1158/0008-5472.CAN-05-0817
    • Yoshida T, Kinoshita H, Segawa T, et al. Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient. Cancer Res 2005;65:9611-9616 (Pubitemid 41541433)
    • (2005) Cancer Research , vol.65 , Issue.21 , pp. 9611-9616
    • Yoshida, T.1    Kinoshita, H.2    Segawa, T.3    Nakamura, E.4    Inoue, T.5    Shimizu, Y.6    Kamoto, T.7    Ogawa, O.8
  • 42
    • 58249110391 scopus 로고    scopus 로고
    • Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
    • Hu R, Dunn TA, Wei S, et al. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res 2009;69:16-22.
    • (2009) Cancer Res , vol.69 , pp. 16-22
    • Hu, R.1    Dunn, T.A.2    Wei, S.3
  • 43
    • 35448947810 scopus 로고    scopus 로고
    • 2-terminal WxxLF motif for aberrant androgen receptor activation in androgen depletion-independent prostate cancer cells
    • DOI 10.1158/0008-5472.CAN-07-1267
    • Dehm SM, Regan KM, Schmidt LJ, Tindall DJ. Selective role of an NH2-terminal WxxLF motif for aberrant androgen receptor activation in androgen depletion independent prostate cancer cells. Cancer Res 2007;67:10067-10077 (Pubitemid 47621258)
    • (2007) Cancer Research , vol.67 , Issue.20 , pp. 10067-10077
    • Dehm, S.M.1    Regan, K.M.2    Schmidt, L.J.3    Tindall, D.J.4
  • 44
    • 53049090989 scopus 로고    scopus 로고
    • A common motif targets huntingtin and the androgen receptor to the proteasome
    • Chandra S, Shao J, Li JX, Li M, Longo FM, Diamond MI. A common motif targets huntingtin and the androgen receptor to the proteasome. J Biol Chem 2008;283:23950-23955
    • (2008) J Biol Chem , vol.283 , pp. 23950-23955
    • Chandra, S.1    Shao, J.2    Li, J.X.3    Li, M.4    Longo, F.M.5    Diamond, M.I.6
  • 45
    • 33846910473 scopus 로고    scopus 로고
    • Androgen receptor amplification is associated with increased cell proliferation in prostate cancer
    • DOI 10.1016/j.humpath.2006.09.008, PII S0046817706005715
    • Haapala K, Kuukasjarvi T, Hyytinen E, Rantala I, Helin HJ, Koivisto PA. Androgen receptor amplification is associated with increased cell proliferation in prostate cancer. Hum Pathol 2007;38:474-478 (Pubitemid 46237655)
    • (2007) Human Pathology , vol.38 , Issue.3 , pp. 474-478
    • Haapala, K.1    Kuukasjarvi, T.2    Hyytinen, E.3    Rantala, I.4    Helin, H.J.5    Koivisto, P.A.6
  • 48
    • 45549090259 scopus 로고    scopus 로고
    • Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer
    • Mehra R, Tomlins SA, Yu J, et al. Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer. Cancer Res 2008;68:3584-3590
    • (2008) Cancer Res , vol.68 , pp. 3584-3590
    • Mehra, R.1    Tomlins, S.A.2    Yu, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.