Metal-Free Synthesis of C-4 Substituted Pyridine Derivatives Using Pyridine-boryl Radicals via a Radical Addition/Coupling Mechanism: A Combined Computational and Experimental Study

Journal of the American Chemical Society

Volumn 139, Issue 10, 2017, Pages 3904-3910

  Wang, Guoqiang ^a   Cao, Jia ^a,b   Gao, Liuzhou ^a   Chen, Wenxin ^a   Huang, Wenhao ^a   Cheng, Xu ^a,c   Li, Shuhua ^a  

^a NANJING UNIVERSITY   (China)

^b YAN'AN UNIVERSITY   (China)

^c NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATION THEORY; DENSITY FUNCTIONAL THEORY; KETONES; PYRIDINE;

4-CYANOPYRIDINE; CONTROLLED EXPERIMENT; COUPLING MECHANISM; METAL-FREE SYNTHESIS; PYRIDINE DERIVATIVES; RADICAL ACCEPTORS; RADICAL ADDITION; UNSATURATED KETONES;

SYNTHESIS (CHEMICAL);

2 CYCLOHEXENONE; ALDEHYDE; CARBONYL DERIVATIVE; CYCLOPROPANE DERIVATIVE; IMINE; KETONE; METHYL GROUP; PYRIDINE DERIVATIVE; RADICAL; TERT BUTYL METHYL ETHER;

ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; CONFORMATION; CONTROLLED STUDY; CROSS COUPLING REACTION; DENSITY FUNCTIONAL THEORY; DIMERIZATION; NUCLEOPHILICITY; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REGIOSELECTIVITY; SUBSTITUTION REACTION; SYNTHESIS; TEMPERATURE SENSITIVITY; THERMODYNAMICS;

EID: 85015160075     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.7b00823     Document Type: Article

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