Autophagy induced by areca nut extract contributes to decreasing cisplatin toxicity in oral squamous cell carcinoma cells: Roles of reactive oxygen species/AMPK signaling

International Journal of Molecular Sciences

Volumn 18, Issue 3, 2017, Pages

  Xu, Zhi ^a   Huang, Chun Ming ^a   Shao, Zhe ^a   Zhao, Xiao Ping ^b   Wang, Meng ^a   Yan, Ting Lin ^a   Zhou, Xiao Cheng ^a   Jiang, Er Hui ^a   Liu, Ke ^a   Shang, Zheng Jun ^a  

^a WUHAN UNIVERSITY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

AMPK mTOR signaling; Areca nut extracts; Autophagy; Cisplatin; Oral squamous cell carcinoma; Reactive oxygen species

Indexed keywords

3 METHYLADENINE; ACETYLCYSTEINE; CASPASE 3; CISPLATIN; DANSYLCADAVERINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; ANTINEOPLASTIC AGENT; LIGHT CHAIN 3, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; PLANT EXTRACT; TARGET OF RAPAMYCIN KINASE;

APOPTOSIS; ARTICLE; AUTOPHAGY; BETEL NUT; CELL VIABILITY; CELL VIABILITY ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG SENSITIVITY; FLOW CYTOMETRY; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MASTICATION; MOUTH SQUAMOUS CELL CARCINOMA; RETROSPECTIVE STUDY; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA CELL; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ARECA; BIOLOGICAL MODEL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; METABOLISM; MOUTH TUMOR; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ARECA; AUTOPHAGY; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; DRUG RESISTANCE, NEOPLASM; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; MOUTH NEOPLASMS; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 85014763711     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms18030524     Document Type: Article

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