Raloxifene induces autophagy-dependent cell death in breast cancer cells via the activation of amp-activated protein kinase

Molecules and Cells

Volumn 38, Issue 2, 2015, Pages 138-144

  Kim, Dong Eun ^a   Kim, Yunha ^a,d   Cho, Dong Hyung ^b   Jeong, Seong Yun ^a   Kim, Sung Bae ^a   Suh, Nayoung ^a   Lee, Jung Shin ^a   Choi, Eun Kyung ^a   Koh, Jae Young ^c   Hwang, Jung Jin ^a   Kim, Choung Soo ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Kyung Hee University   (South Korea)

^c Asan Medical Center   (South Korea)

^d Korea Institute of Science and Technology   (South Korea)

Author keywords

AMPK; ATP; Autophagy; Breast cancer; Raloxifene

Indexed keywords

3 METHYLADENINE; ADENOSINE TRIPHOSPHATE; BECLIN 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; RALOXIFENE; SMALL INTERFERING RNA; 3-METHYLADENINE; ADENINE; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; ATG5 PROTEIN, HUMAN; BECN1 PROTEIN, HUMAN; CASPASE; MAP1LC3A PROTEIN, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN;

APOPTOSIS; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CELL DEATH; CONJUGATE; CONTROLLED STUDY; ENZYME ACTIVATION; FLUORESCENCE; HUMAN; HUMAN CELL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; BREAST TUMOR; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; MCF 7 CELL LINE; METABOLISM;

ADENINE; AMP-ACTIVATED PROTEIN KINASES; ANTINEOPLASTIC AGENTS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BREAST NEOPLASMS; CASPASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MCF-7 CELLS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; RALOXIFENE HYDROCHLORIDE; SIGNAL TRANSDUCTION;

EID: 84949941850     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.14348/molcells.2015.2193     Document Type: Article

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