AMPK inhibits MTDH expression via GSK3β and SIRT1 activation: Potential role in triple negative breast cancer cell proliferation

FEBS Journal

Volumn 282, Issue 20, 2015, Pages 3971-3985

  Gollavilli, Paradesi Naidu ^a,b   Kanugula, Anantha Koteswararao ^a   Koyyada, Rajeswari ^a   Karnewar, Santosh ^a,b   Neeli, Praveen Kumar ^a   Kotamraju, Srigiridhar ^a,b  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH   (India)

Author keywords

AMPK; breast cancer; metadherin; SIRT1; tumour promotion and progression

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; COMPOUND C; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LITHIUM CHLORIDE; METADHERIN; METFORMIN; MYC PROTEIN; ONCOPROTEIN; PROTEIN P53; PROTEIN SERINE THREONINE KINASE INHIBITOR; SELISISTAT; SERINE; SIRTUIN 1; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; ANTINEOPLASTIC AGENT; CELL ADHESION MOLECULE; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MTDH PROTEIN, HUMAN; PRKAA1 PROTEIN, HUMAN; SIRT1 PROTEIN, HUMAN; TUMOR PROTEIN;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER CELL LINE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DEACETYLATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; METASTASIS INHIBITION; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; ADENOCARCINOMA; AGONISTS; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; CARCINOMA; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; RNA INTERFERENCE; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR CELL LINE;

ADENOCARCINOMA; AMP-ACTIVATED PROTEIN KINASES; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CARCINOMA; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOGEN SYNTHASE KINASE 3; HUMANS; HYPOGLYCEMIC AGENTS; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA INTERFERENCE; SIRTUIN 1; TRIPLE NEGATIVE BREAST NEOPLASMS;

EID: 84944278178     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13391     Document Type: Article

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