메뉴 건너뛰기




Volumn 16, Issue 4, 2016, Pages 1078-1088

Exercise alleviates depression related systemic inflammation in chronic obstructive pulmonary disease patients.

Author keywords

Aerobic exercise; Chronic obstructive pulmonary disease; Depression; Inflammatory cytokine

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 4; INTERLEUKIN 6; TUMOR NECROSIS FACTOR;

EID: 85014736772     PISSN: 16806905     EISSN: None     Source Type: Journal    
DOI: 10.4314/ahs.v16i4.25     Document Type: Article
Times cited : (23)

References (71)
  • 2
    • 77249136293 scopus 로고    scopus 로고
    • Australian Institute of Health and Welfare, Dec 28, Available online
    • Australian Institute of Health and Welfare. COPD (chronic obstructive pulmonary disease). cited 2013 Dec 28. Available online: http://www.aihw.gov.au/copd/
    • (2013) COPD (Chronic Obstructive Pulmonary Disease).
  • 3
    • 84882534885 scopus 로고    scopus 로고
    • Global Strategy for the diagnosis
    • Global Initiative for Chronic Obstructive Lung Disease; Revised , . Available online:
    • Global Strategy for the diagnosis, management and prevention of chronic obstruvtive pulmonary disease. Global Initiative for Chronic Obstructive Lung Disease; Revised 2013. Available online: http://www.goldcopd. org/(accessed December 2013).
    • (2013) Management and Prevention of Chronic Obstruvtive Pulmonary Disease
  • 4
    • 79959597788 scopus 로고    scopus 로고
    • Prevalence of Depression in Stable Chronic Obstructive Pulmonary Disease
    • De S. Prevalence of Depression in Stable Chronic Obstructive Pulmonary Disease. Indian J Chest Dis Allied Sci 2011; 53:35-39
    • (2011) Indian J Chest Dis Allied Sci , vol.53 , pp. 35-39
    • De, S.1
  • 6
    • 55249090655 scopus 로고    scopus 로고
    • ACCP Workshop Panel on Anxiety and Depression in COPD
    • Anxiety and depression in COPD: current understanding, unanswered questions, and research needs, PubMed
    • Maurer J, Rebbapragada V, Borson S, Goldstein R, Kunik ME, Yohannes AM, Hanania NA, ACCP Workshop Panel on Anxiety and Depression in COPD: Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest 2008; 134(4 Suppl):43S–56S. PubMed
    • (2008) Chest , vol.134 , Issue.4 , pp. 43S-56S
    • Maurer, J.1    Rebbapragada, V.2    Borson, S.3    Goldstein, R.4    Kunik, M.E.5    Yohannes, A.M.6    Hanania, N.A.7
  • 7
    • 19044376762 scopus 로고    scopus 로고
    • Surprisingly high prevalence of anxiety and depression in chronic breathing disorders
    • PubMed
    • Kunik ME, Roundy K, Veazey C, Souchek J, Richardson P, Wray NP, Stanley MA: Surprisingly high prevalence of anxiety and depression in chronic breathing disorders. Chest 2005;127(4):1205–1211. PubMed
    • (2005) Chest , vol.127 , Issue.4 , pp. 1205-1211
    • Kunik, M.E.1    Roundy, K.2    Veazey, C.3    Souchek, J.4    Richardson, P.5    Wray, N.P.6    Stanley, M.A.7
  • 9
    • 84859911487 scopus 로고    scopus 로고
    • Treatments for anxiety and depression in patients with chronic obstructive pulmonary disease: A literature review
    • PubMed
    • Cafarella PA, Effing TW, Usmani ZA, Frith PA. Treatments for anxiety and depression in patients with chronic obstructive pulmonary disease: a literature review. Respi-rology 2012; 17:627-38 PubMed.
    • (2012) Respi-Rology , vol.17 , pp. 627-638
    • Cafarella, P.A.1    Effing, T.W.2    Usmani, Z.A.3    Frith, P.A.4
  • 10
    • 84917683214 scopus 로고    scopus 로고
    • Anxiety and depression-Important psychological comorbidities of COPD
    • PubMed
    • Pumar MI1, Gray CR1, Walsh JR1, Yang IA1, Rolls TA1, Ward DL1. Anxiety and depression-Important psychological comorbidities of COPD. J Thorac Dis 2014; 6(11):1615-31. PubMed
    • (2014) J Thorac Dis , vol.6 , Issue.11 , pp. 1615-1631
    • Mi, P.1    Cr, G.2    Jr, W.3    Ia, Y.4    Ta, R.5
  • 11
    • 84884331422 scopus 로고    scopus 로고
    • Bidirectional associations between clinically relevant depression or anxiety and COPD: A systematic review and meta-analysis
    • PubMed
    • Atlantis E, Fahey P, Cochrane B, Smith S. Bidirectional associations between clinically relevant depression or anxiety and COPD: a systematic review and meta-analysis. Chest 2013; 144:766-77 PubMed .
    • (2013) Chest , vol.144 , pp. 766-777
    • Atlantis, E.1    Fahey, P.2    Cochrane, B.3    Smith, S.4
  • 12
    • 0036433448 scopus 로고    scopus 로고
    • Anxiety and depression are related to the outcome of emergency treatment in patients with obstructive pulmonary disease
    • PubMed
    • Dahlen I, Janson C. Anxiety and depression are related to the outcome of emergency treatment in patients with obstructive pulmonary disease. Chest 2002; 122: 1633-7 PubMed.
    • (2002) Chest , vol.122 , pp. 1633-1637
    • Dahlen, I.1    Janson, C.2
  • 16
    • 33749072534 scopus 로고    scopus 로고
    • Increased stressinduced inflammatoryresponses in male patients with major depression and increased early life stress
    • PubMed
    • Pace TW, Mletzko TC, Alagbe O, Musselman DL, Nemeroff CB, Miller AH, Heim CM. Increased stressinduced inflammatoryresponses in male patients with major depression and increased early life stress. Am J Psychiatry 2006; 163:1630-3 PubMed
    • (2006) Am J Psychiatry , vol.163 , pp. 1630-1633
    • Pace, T.W.1    Mletzko, T.C.2    Alagbe, O.3    Musselman, D.L.4    Nemeroff, C.B.5    Miller, A.H.6    Heim, C.M.7
  • 18
    • 65649152524 scopus 로고    scopus 로고
    • Associations of depression with C-reactive protein, IL-1, and IL-6: A meta-analysis
    • PubMed
    • Howren MB, Lamkin DM, Suls J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med 2009;71:171–186. PubMed
    • (2009) Psychosom Med , vol.71 , pp. 171-186
    • Howren, M.B.1    Lamkin, D.M.2    Suls, J.3
  • 19
    • 84877888951 scopus 로고    scopus 로고
    • Systemic inflammation, depression and obstructive pulmonary function: A population-based study
    • Lu Y, Feng L, Feng L, Nyunt MS, Yap KB, Ng TP. Systemic inflammation, depression and obstructive pulmonary function: a population-based study. Respir Res 2013;14:53.
    • (2013) Respir Res , vol.14 , pp. 53
    • Lu, Y.1    Feng, L.2    Feng, L.3    Nyunt, M.S.4    Yap, K.B.5    Ng, T.P.6
  • 20
    • 84871512229 scopus 로고    scopus 로고
    • Interleukin-6, C-reactive protein and interleukin-10 after antidepressant treatment in people with depression: A meta-analysis
    • PubMed
    • Hiles SA, Baker AL, de Malmanche T, Attia J. Interleukin-6, C-reactive protein and interleukin-10 after antidepressant treatment in people with depression: a meta-analysis. Psychol Med 2012;42(10):2015–2026. PubMed
    • (2012) Psychol Med , vol.42 , Issue.10 , pp. 2015-2026
    • Hiles, S.A.1    Baker, A.L.2    De Malmanche, T.3    Attia, J.4
  • 24
    • 85014772427 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, Retrieved on 12/01/2006
    • GOLD Scientific Committee. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. GOLD Scientific Committee http://www.goldcopd.org/, Retrieved on 12/01/2006.
    • GOLD Scientific Committee
  • 26
    • 85014774112 scopus 로고    scopus 로고
    • American College of Sports Medicine
    • Guidelines for graded exercise testing and exercise prescription
    • American College of Sports Medicine. Guidelines for graded exercise testing and exercise prescription, Lea & Febiger, Philadelphia, 2005.
    • (2005) Lea & Febiger, Philadelphia
  • 28
    • 84858406715 scopus 로고    scopus 로고
    • Available at:, Accessed August 26
    • NHLBI Morbidity and Mortality Chart book. Available at: http://www.nhlbi.nih.gov/resources/docs/cht-bookhtm Accessed August 26, 2011.
    • (2011) NHLBI Morbidity and Mortality Chart Book
  • 29
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers C, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 2006; 3: e442.
    • (2006) Plos Med , pp. 3
    • Mathers, C.1    Loncar, D.2
  • 31
    • 77954619669 scopus 로고    scopus 로고
    • Proteomics-based biomarkers in chronic obstructive pulmonary disease
    • PubMed
    • Chen H, Wang D, Bai C, Wang X. Proteomics-based biomarkers in chronic obstructive pulmonary disease. J Proteome Res 2010; 9:2798–808. PubMed
    • (2010) J Proteome Res , vol.9 , pp. 2798-2808
    • Chen, H.1    Wang, D.2    Bai, C.3    Wang, X.4
  • 33
    • 84878923139 scopus 로고    scopus 로고
    • Inflammatory cytokines in depression: Neurobiological mechanisms and therapeutic implications
    • PubMed
    • Felger JC, Lotrich FE. Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications. Neuroscience 2013;246:199–229. PubMed
    • (2013) Neuroscience , vol.246 , pp. 199-229
    • Felger, J.C.1    Lotrich, F.E.2
  • 34
    • 63449122724 scopus 로고    scopus 로고
    • Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression.
    • PubMed
    • Miller AH, Maletic V, Raison CL. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiatry 2009;65(9):732– 41. PubMed
    • (2009) Biol Psychiatry , vol.65 , Issue.9
    • Miller, A.H.1    Maletic, V.2    Raison, C.L.3
  • 35
    • 65649152524 scopus 로고    scopus 로고
    • Associations of depression with C-reactive protein, IL-1, and IL-6: A meta-analysis
    • PubMed
    • Howren MB, Lamkin DM, Suls J. Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis. Psychosom Med 2009;71(2):171–86. PubMed
    • (2009) Psychosom Med , vol.71 , Issue.2 , pp. 171-186
    • Howren, M.B.1    Lamkin, D.M.2    Suls, J.3
  • 36
    • 33846836936 scopus 로고    scopus 로고
    • An exercise intervention without weight loss decreases circulating interleukin-6 in lean and obese men with and without type 2 diabetes mellitus
    • Dekker M, Lee S, Hudson R, Kilpatrick K, Graham T, Ross R. An exercise intervention without weight loss decreases circulating interleukin-6 in lean and obese men with and without type 2 diabetes mellitus. Metabolism 2007;56(3):332–8.
    • (2007) Metabolism , vol.56 , Issue.3 , pp. 332-338
    • Dekker, M.1    Lee, S.2    Hudson, R.3    Kilpatrick, K.4    Graham, T.5    Ross, R.6
  • 39
    • 1942440882 scopus 로고    scopus 로고
    • Effects of hy-pocaloric diet and exercise training on inflammation and adipocyte lipolysis in obese postmenopausal women
    • You T, Berman D, Ryan A, Nicklas B. Effects of hy-pocaloric diet and exercise training on inflammation and adipocyte lipolysis in obese postmenopausal women. J Clin Endocrinol Metab 2004; 89(4):1739–46.
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.4 , pp. 1739-1746
    • You, T.1    Berman, D.2    Ryan, A.3    Nicklas, B.4
  • 40
    • 0035487711 scopus 로고    scopus 로고
    • Effect of aerobic exercise training on plasma levels of tumor necrosis factor alpha in patients with heart failure
    • PubMed
    • Larsen A, Aukrust P, Aarsland T, Dickstein K. Effect of aerobic exercise training on plasma levels of tumor necrosis factor alpha in patients with heart failure. Am J Cardiol 2001; 88(7):805–8. PubMed
    • (2001) Am J Cardiol , vol.88 , Issue.7 , pp. 805-808
    • Larsen, A.1    Aukrust, P.2    Aarsland, T.3    Dickstein, K.4
  • 41
    • 20444481043 scopus 로고    scopus 로고
    • Effects of diet and/or exercise on the adipocytokine and inflammatory cytokine levels of postmenopausal women with type 2 diabetes
    • PubMed
    • Giannopoulou I, Fernhall B, Carhart R, Weinstock R, Baynard T, Figueroa A, Kanaley J. Effects of diet and/or exercise on the adipocytokine and inflammatory cytokine levels of postmenopausal women with type 2 diabetes. Metabolism 2005; 54:866–75. PubMed
    • (2005) Metabolism , vol.54 , pp. 866-875
    • Giannopoulou, I.1    Fernhall, B.2    Carhart, R.3    Weinstock, R.4    Baynard, T.5    Figueroa, A.6    Kanaley, J.7
  • 42
    • 73649129621 scopus 로고    scopus 로고
    • The effect of exercise on serum levels of in-terleukin-18 and components of the metabolic syndrome
    • Troseid M, Lappegard KT, Mollnes T, Arnesen H, Seljeflot I. The effect of exercise on serum levels of in-terleukin-18 and components of the metabolic syndrome. Metab Syndr Relat Disord 2009;7(6):579-84.
    • (2009) Metab Syndr Relat Disord , vol.7 , Issue.6 , pp. 579-584
    • Troseid, M.1    Lappegard, K.T.2    Mollnes, T.3    Arnesen, H.4    Seljeflot, I.5
  • 43
    • 26444457387 scopus 로고    scopus 로고
    • Effect of exercise training on plasma levels of C-reactive protein in healthy adults: The HERITAGE Family Study
    • PubMed
    • Lakka T, Lakka H, Rankinen T, Leon A, Rao D, Skinner J, Wilmore J, Bouchard C. Effect of exercise training on plasma levels of C-reactive protein in healthy adults: the HERITAGE Family Study. Eur Heart J 2005; 26:2018–25. PubMed
    • (2005) Eur Heart J , vol.26 , pp. 2018-2025
    • Lakka, T.1    Lakka, H.2    Rankinen, T.3    Leon, A.4    Rao, D.5    Skinner, J.6    Wilmore, J.7    Bouchard, C.8
  • 44
    • 77954192215 scopus 로고    scopus 로고
    • Effect of exercise training on chronic inflammation.
    • PubMed
    • Beavers K, Brinkley T, Nicklas B. Effect of exercise training on chronic inflammation. Clin Chim Acta 2010; 411(11-12):785-93. PubMed
    • (2010) Clin Chim Acta , vol.411 , pp. 785-793
    • Beavers, K.1    Brinkley, T.2    Nicklas, B.3
  • 45
  • 46
    • 0033549059 scopus 로고    scopus 로고
    • Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing isch-emic heart disease
    • PubMed
    • Smith J, Dykes R, Douglas J, Krishnaswamy G, Berk S. Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing isch-emic heart disease. JAMA 1999; 281:1722–7. PubMed
    • (1999) JAMA , vol.281 , pp. 1722-1727
    • Smith, J.1    Dykes, R.2    Douglas, J.3    Krishnaswamy, G.4    Berk, S.5
  • 47
    • 55549108701 scopus 로고    scopus 로고
    • Exercise training induced lowering of inflammatory (CD14+CD16+) monocytes: A role in the anti-inflammatory influence of exercise?
    • PubMed
    • Timmerman K, Flynn M, Coen P, Markofski M, Pence B. Exercise training induced lowering of inflammatory (CD14+CD16+) monocytes: a role in the anti-inflammatory influence of exercise? J Leukoc Biol 2008; 84:1271–8. PubMed
    • (2008) J Leukoc Biol , vol.84 , pp. 1271-1278
    • Timmerman, K.1    Flynn, M.2    Coen, P.3    Markofski, M.4    Pence, B.5
  • 49
    • 33646010308 scopus 로고    scopus 로고
    • Physical activity status, but not age, influences inflammatory biomarkers and toll-like receptor 4
    • Apolzan J, Flynn M, McFarlin B, Campbell W. Physical activity status, but not age, influences inflammatory biomarkers and toll-like receptor 4. J Gerontol A Biol Sci Med Sci 2006; 61:388–93.
    • (2006) J Gerontol a Biol Sci Med Sci , vol.61 , pp. 388-393
    • Apolzan, J.1    Flynn, M.2    McFarlin, B.3    Campbell, W.4
  • 52
    • 33845310307 scopus 로고    scopus 로고
    • Exercise and the inflammatory response in chronic obstructive pulmonary disease (COPD)--Does training confer anti-inflammatory properties in COPD
    • PubMed
    • Garrod R, Ansley P, Canavan J, Jewell A. Exercise and the inflammatory response in chronic obstructive pulmonary disease (COPD)--Does training confer anti-inflammatory properties in COPD?. Med Hypotheses 2007; 68(2):291-8. PubMed
    • (2007) Med Hypotheses , vol.68 , Issue.2 , pp. 291-298
    • Garrod, R.1    Ansley, P.2    Canavan, J.3    Jewell, A.4
  • 53
    • 33746270454 scopus 로고    scopus 로고
    • Exercise, inflammation, and innate immunity
    • PubMed
    • Woods J, Vieira V, Keylock K. Exercise, inflammation, and innate immunity. Neurol Clin 2006; 24(3):585– 99. PubMed
    • (2006) Neurol Clin , vol.24 , Issue.3
    • Woods, J.1    Vieira, V.2    Keylock, K.3
  • 54
    • 79960616418 scopus 로고    scopus 로고
    • Moderate exerciseimproves depression parameters in treatment-resistant patients with major depressive disorder
    • PubMed
    • Mota-Pereira J, Silverio J, Carvalho S, Ribeiro JC, Fonte D, Ramos J. Moderate exerciseimproves depression parameters in treatment-resistant patients with major depressive disorder. J Psychiatr Res 2011;45(8):1005-11. PubMed
    • (2011) J Psychiatr Res , vol.45 , Issue.8 , pp. 1005-1011
    • Mota-Pereira, J.1    Silverio, J.2    Carvalho, S.3    Ribeiro, J.C.4    Fonte, D.5    Ramos, J.6
  • 56
    • 0026230863 scopus 로고
    • The effect of exercise on depressive symptoms in the moderately depressed elderly
    • McNeil JK, LeBlanc EM, Joyner M. The effect of exercise on depressive symptoms in the moderately depressed elderly. Psychol Aging 1991;6:487–8. PubMed
    • (1991) Psychol Aging , vol.6 , pp. 487-488
    • McNeil, J.K.1    Leblanc, E.M.2    Joyner, M.3
  • 58
    • 77954546739 scopus 로고    scopus 로고
    • Depressive symptom outcomes of physical activity interventions: Meta-analysis findings
    • PubMed
    • Conn V. Depressive symptom outcomes of physical activity interventions: meta-analysis findings. Ann. Behav. Med 2010;39 (2):128–138. PubMed
    • (2010) Ann. Behav. Med , vol.39 , Issue.2 , pp. 128-138
    • Conn, V.1
  • 59
    • 12444281851 scopus 로고    scopus 로고
    • Exercise and clinical depression: Examining twopsychological mechanisms
    • Craft L. Exercise and clinical depression: examining twopsychological mechanisms. Psychology of Sport and Exercise 2005; 6(2):151-171.
    • (2005) Psychology of Sport and Exercise , vol.6 , Issue.2 , pp. 151-171
    • Craft, L.1
  • 62
    • 0030989123 scopus 로고    scopus 로고
    • A randomized controlled trial of the effect of exercise on sleep
    • PubMed
    • Singh NA, Clements KM, Fiatarone MA. A randomized controlled trial of the effect of exercise on sleep. Sleep 1997; 20: 95–101. PubMed
    • (1997) Sleep , vol.20 , pp. 95-101
    • Singh, N.A.1    Clements, K.M.2    Fiatarone, M.A.3
  • 64
    • 78649908701 scopus 로고    scopus 로고
    • Depression: A repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition?
    • Wager-Smith K, Markou A. Depression: a repair response to stress-induced neuronal microdamage that can grade into a chronic neuroinflammatory condition?. Neurosci Biobehav Rev 2011; 35 (3):742–764.
    • (2011) Neurosci Biobehav Rev , vol.35 , Issue.3 , pp. 742-764
    • Wager-Smith, K.1    Markou, A.2
  • 65
    • 79953662385 scopus 로고    scopus 로고
    • Immune system to brain signaling: Neuropsychopharmacological implications
    • PubMed
    • Capuro L, Miller AH. Immune system to brain signaling: neuropsychopharmacological implications. Pharmacol. Ther 2011;130 (2):226–238. PubMed
    • (2011) Pharmacol. Ther , vol.130 , Issue.2 , pp. 226-238
    • Capuro, L.1    Miller, A.H.2
  • 66
    • 45849103124 scopus 로고    scopus 로고
    • Inflammation and its discontents: The role of cytokines in the pathophysiology of major depression
    • García-Bueno B, Caso JR, Leza JC. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Neurosci Biobehav Rev 2008;32(6):1136-51.
    • (2008) Neurosci Biobehav Rev , vol.32 , Issue.6 , pp. 1136-1151
    • García-Bueno, B.1    Caso, J.R.2    Leza, J.C.3
  • 67
    • 45849103124 scopus 로고    scopus 로고
    • Stress as a neuroinflammatory condition in brain: Damaging and protective mechanisms
    • García-Bueno B, Caso JR, Leza JC. Stress as a neuroinflammatory condition in brain: damaging and protective mechanisms. Neurosci Biobehav Rev 2008;32(6):1136-51.
    • (2008) Neurosci Biobehav Rev , vol.32 , Issue.6 , pp. 1136-1151
    • García-Bueno, B.1    Caso, J.R.2    Leza, J.C.3
  • 70
  • 71
    • 71549167579 scopus 로고    scopus 로고
    • Regulation of adult neu-rogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action
    • Lucassen P, Meerlo P, Naylor A, Van Dam A, Dayer A, Fuchs E, Oomen, C, Czeh B. Regulation of adult neu-rogenesis by stress, sleep disruption, exercise and inflammation: implications for depression and antidepressant action. European Neuropsychopharmacology 2010; 20:1–17.
    • (2010) European Neuropsychopharmacology , vol.20 , pp. 1-17
    • Lucassen, P.1    Meerlo, P.2    Naylor, A.3    Van Dam, A.4    Dayer, A.5    Fuchs, E.6    Oomen, C.7    Czeh, B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.