Formulation of food grade nanostructured lipid carrier (NLC) for potential applications in medicinal-functional foods

Journal of Drug Delivery Science and Technology

Volumn 39, Issue , 2017, Pages 50-58

  Babazadeh, Afshin ^a,b   Ghanbarzadeh, Babak ^b   Hamishehkar, Hamed ^c  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF TABRIZ   (Iran)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Medicinal functional foods; Nanodelivery system; Nanostructured lipid carrier; NLC

Indexed keywords

LIPID; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; NUTRACEUTICAL; OIL; SURFACTANT; T RESVERATROL; UNCLASSIFIED DRUG;

ARTICLE; COOLING; DRUG FORMULATION; DRUG STABILITY; FORTIFIED FOOD; FUNCTIONAL FOOD; LIPID ANALYSIS; NANOENCAPSULATION; PARTICLE SIZE; STORAGE; ULTRASOUND;

EID: 85014695019     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jddst.2017.03.001     Document Type: Article

References (44)

1. [1] Müller, R.H., Radtke, M., Wissing, S.A., Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv. Drug Deliv. Rev. 54 (2002), 131–155.
2. [2] Schäfer-Korting, M., Mehnert, W., Korting, H.-C., Lipid nanoparticles for improved topical application of drugs for skin diseases. Adv. drug Deliv. Rev. 59 (2007), 427–443.
3. [3] Chen, C.-C., Tsai, T.-H., Huang, Z.-R., Fang, J.-Y., Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: physicochemical characterization and pharmacokinetics. Eur. J. Pharm. Biopharm. 74 (2010), 474–482.
4. [4] Esposito, E., Vries, H., Pol, S., Boschi, F., Calderan, L., Production, physico-chemical characterization and biodistribution studies of lipid nanoparticles. J. Nanomedicine Nanotechnol., 6, 2015, 1.
5. [5] Fang, J.-Y., Fang, C.-L., Liu, C.-H., Su, Y.-H., Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC). Eur. J. Pharm. Biopharm. 70 (2008), 633–640.
6. [6] Pezeshky, A., Ghanbarzadeh, B., Hamishehkar, H., Moghadam, M., Babazadeh, A., Vitamin A palmitate-bearing nanoliposomes: preparation and characterization. Food Biosci. 13 (2016), 49–55.
7. [7] Babazadeh, A., Ghanbarzadeh, B., Hamishehkar, H., Novel nanostructured lipid carriers as a promising food grade delivery system for rutin. J. Funct. Foods 26 (2016), 167–175.
8. [8] Mahdavi, H., Mirzadeh, H., Hamishehkar, H., Jamshidi, A., Fakhari, A., Emami, J., Najafabadi, A.R., Gilani, K., Minaiyan, M., Najafi, M., The effect of process parameters on the size and morphology of poly (D, L-lactide-co-glycolide) micro/nanoparticles prepared by an oil in oil emulsion/solvent evaporation technique. J. Appl. Polym. Sci. 116 (2010), 528–534.
9. [9] Fundarò, A., Cavalli, R., Bargoni, A., Vighetto, D., Zara, G.P., Gasco, M.R., Non-stealth and stealth solid lipid nanoparticles (SLN) carrying doxorubicin: pharmacokinetics and tissue distribution after iv administration to rats. Pharmacol. Res. 42 (2000), 337–343.
10. [10] Kim, B.-D., Na, K., Choi, H.-K., Preparation and characterization of solid lipid nanoparticles (SLN) made of cacao butter and curdlan. Eur. J. Pharm. Sci. 24 (2005), 199–205.
11. [11] Lopez-Huertas, E., Health effects of oleic acid and long chain omega-3 fatty acids (EPA and DHA) enriched milks. A review of intervention studies. Pharmacol. Res. 61 (2010), 200–207.
12. [12] Tamjidi, F., Shahedi, M., Varshosaz, J., Nasirpour, A., Nanostructured lipid carriers (NLC): a potential delivery system for bioactive food molecules. Innov. Food Sci. Emerg. Technol. 19 (2013), 29–43.
13. [13] Valls, V., Goicoechea, M., Muniz, P., Saez, G., Cabo, J., Effect of corn oil and vitamin E on the oxidative status of adipose tissues and liver in rat. Food Chem. 81 (2003), 281–286.
14. [14] Cottrell, T., van Peij, J., 7 Sorbitan esters and polysorbates. Emuls. food Technol., 2004, 162.
15. [15] Patel, H.R., Patel, R.P., Patel, M., Poloxamers: a pharmaceutical excipients with therapeutic behaviors. Int. J. PharmTech Res. 1 (2009), 299–303.
16. [16] Kerwin, B.A., Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways. J. Pharm. Sci. 97 (2008), 2924–2935.
17. [17] Emulsifiers in Food Technology, 2008, Blackwell Publishing, Northampton, UK 247 pp.
18. [18] McClements, D.J., Rao, J., Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity. Crit. Rev. food Sci. Nutr. 51 (2011), 285–330.
19. [19] Weiss, J., Decker, E.A., McClements, D.J., Kristbergsson, K., Helgason, T., Awad, T., Solid lipid nanoparticles as delivery systems for bioactive food components. Food Biophys. 3 (2008), 146–154.
20. [20] Heim, K.E., Tagliaferro, A.R., Bobilya, D.J., Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. J. Nutr. Biochem. 13 (2002), 572–584.
21. [21] Rousseau, D., Fat crystals and emulsion stability—a review. Food Res. Int. 33 (2000), 3–14.
22. [22] Radtke, M., Müller, R.H., Nanostructured lipid drug carriers. New Drugs 2 (2001), 48–52.
23. [23] Fathi, M., Varshosaz, J., Mohebbi, M., Shahidi, F., Hesperetin-loaded solid lipid nanoparticles and nanostructure lipid carriers for food fortification: preparation, characterization, and modeling. Food Bioprocess Technol. 6 (2013), 1464–1475.
24. [24] The, H.L.B., System: a time-saving guide to emulsifier selection. ICI Am. Inc., 1984 19 pp.
25. [25] Bose, S., Michniak-Kohn, B., Preparation and characterization of lipid based nanosystems for topical delivery of quercetin. Eur. J. Pharm. Sci. 48 (2013), 442–452.
26. [26] Yang, Y., Corona, A., Schubert, B., Reeder, R., Henson, M.A., The effect of oil type on the aggregation stability of nanostructured lipid carriers. J. colloid interface Sci. 418 (2014), 261–272.
27. [27] Han, F., Li, S., Yin, R., Liu, H., Xu, L., Effect of surfactants on the formation and characterization of a new type of colloidal drug delivery system: nanostructured lipid carriers. Colloids Surf. A Physicochem. Eng. Aspects 315 (2008), 210–216.
28. [28] McClements, D.J., Advances in fabrication of emulsions with enhanced functionality using structural design principles. Curr. Opin. Colloid & Interface Sci. 17 (2012), 235–245.
29. [29] Jenkins, P., Snowden, M., Depletion flocculation in colloidal dispersions. Adv. colloid interface Sci. 68 (1996), 57–96.
30. [30] Hejri, A., Khosravi, A., Gharanjig, K., Hejazi, M., Optimisation of the formulation of β-carotene loaded nanostructured lipid carriers prepared by solvent diffusion method. Food Chem. 141 (2013), 117–123.
31. [31] Mohammadi, M., Ghanbarzadeh, B., Hamishehkar, H., Formulation of nanoliposomal vitamin D3 for potential application in beverage fortification. Adv. Pharm. Bull., 4, 2014, 569.
32. [32] Hu, F.-Q., Jiang, S.-P., Du, Y.-Z., Yuan, H., Ye, Y.-Q., Zeng, S., Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system. Colloids Surf. B Biointerfaces 45 (2005), 167–173.
33. [33] Chanamai, R., McClements, D., Depletion flocculation of beverage emulsions by gum arabic and modified starch. J. Food Sci. 66 (2001), 457–463.
34. [34] Saberi, A.H., Fang, Y., McClements, D.J., Fabrication of vitamin E-enriched nanoemulsions: factors affecting particle size using spontaneous emulsification. J. colloid interface Sci. 391 (2013), 95–102.
35. [35] Sato, K., Crystallization behaviour of fats and lipids—a review. Chem. Eng. Sci. 56 (2001), 2255–2265.
36. [36] Sagalowicz, L., Leser, M.E., Delivery systems for liquid food products. Curr. Opin. Colloid & Interface Sci. 15 (2010), 61–72.
37. [37] Helgason, T., Awad, T., Kristbergsson, K., McClements, D.J., Weiss, J., Influence of polymorphic transformations on gelation of tripalmitin solid lipid nanoparticle suspensions. J. Am. Oil Chemists’ Soc. 85 (2008), 501–511.
38. [38] Jenning, V., Gohla, S.H., Encapsulation of retinoids in solid lipid nanoparticles (SLN). J. Microencapsul. 18 (2001), 149–158.
39. [39] Mason, T., Power ultrasound in food processing—the way. Ultrasound food Process., 1998, 105.
40. [40] McClements, D.J., Li, Y., Structured emulsion-based delivery systems: controlling the digestion and release of lipophilic food components. Adv. colloid interface Sci. 159 (2010), 213–228.
41. [41] Kentish, S., Wooster, T., Ashokkumar, M., Balachandran, S., Mawson, R., Simons, L., The use of ultrasonics for nanoemulsion preparation. Innov. Food Sci. Emerg. Technol. 9 (2008), 170–175.
42. [42] Wu, L., Zhang, J., Watanabe, W., Physical and chemical stability of drug nanoparticles. Adv. drug Deliv. Rev. 63 (2011), 456–469.
43. [43] Rasti, B., Jinap, S., Mozafari, M., Yazid, A., Comparative study of the oxidative and physical stability of liposomal and nanoliposomal polyunsaturated fatty acids prepared with conventional and Mozafari methods. Food Chem. 135 (2012), 2761–2770.
44. [44] Sun, R., Zhao, G., Ni, S., Xia, Q., Lipid based nanocarriers with different lipid compositions for topical delivery of resveratrol: comparative analysis of characteristics and performance. J. Drug Deliv. Sci. Technol. 24 (2014), 591–600.