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Volumn 8, Issue 6, 2016, Pages 505-517

Adipocyte-derived microvesicles from obese mice induce M1 macrophage phenotype through secreted miR-155

Author keywords

Adipocyte; Macrophage; Microvesicle; miR 155; Phenotype

Indexed keywords

GLUCOSE; INSULIN; JANUS KINASE; MICRORNA 155; STAT1 PROTEIN; STAT6 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; MICRORNA; MIRN155 MICRORNA, MOUSE; SOCS1 PROTEIN, MOUSE; STAT PROTEIN;

EID: 85014525055     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjw040     Document Type: Article
Times cited : (144)

References (43)
  • 1
    • 79551625424 scopus 로고    scopus 로고
    • Microvesicle-mediated RNA molecule delivery system using monocytes/macrophages
    • Akao, Y., Iio, A., Itoh, T., et al. (2011). Microvesicle-mediated RNA molecule delivery system using monocytes/macrophages. Mol. Ther. 19, 395-399.
    • (2011) Mol. Ther. , vol.19 , pp. 395-399
    • Akao, Y.1    Iio, A.2    Itoh, T.3
  • 2
    • 0036595049 scopus 로고    scopus 로고
    • Suppressors of cytokine signalling (SOCS) in the immune system
    • Alexander, W.S. (2002). Suppressors of cytokine signalling (SOCS) in the immune system. Nat. Rev. Immunol 2, 410-416.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 410-416
    • Alexander, W.S.1
  • 3
    • 84960106182 scopus 로고    scopus 로고
    • Adipose tissue macrophages: Going off track during obesity
    • Boutens, L. and Stienstra, R. (2016). Adipose tissue macrophages: going off track during obesity. Diabetologia 59, 879-894.
    • (2016) Diabetologia , vol.59 , pp. 879-894
    • Boutens, L.1    Stienstra, R.2
  • 4
    • 84867420120 scopus 로고    scopus 로고
    • Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155
    • Cai, X., Yin, Y., Li, N., et al. (2012). Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155. J. Mol. Cell Biol. 4, 341-343.
    • (2012) J. Mol. Cell Biol. , vol.4 , pp. 341-343
    • Cai, X.1    Yin, Y.2    Li, N.3
  • 5
    • 84927624671 scopus 로고    scopus 로고
    • Microparticles release by adipocytes act as 'find-me' signals to promote macrophage migration
    • Eguchi, A., Mulya, A., Lazic, M., et al. (2015). Microparticles release by adipocytes act as 'find-me' signals to promote macrophage migration. PLoS One 10, e0123110.
    • (2015) PLoS One , vol.10
    • Eguchi, A.1    Mulya, A.2    Lazic, M.3
  • 6
    • 70350560546 scopus 로고    scopus 로고
    • Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice
    • Fujisaka, S., Usui, I., Bukhari, A., et al. (2009). Regulatory mechanisms for adipose tissue M1 and M2 macrophages in diet-induced obese mice. Diabetes 58, 2574-2582.
    • (2009) Diabetes , vol.58 , pp. 2574-2582
    • Fujisaka, S.1    Usui, I.2    Bukhari, A.3
  • 7
    • 84894559222 scopus 로고    scopus 로고
    • Local proliferation of macrophages in adipose tissue during obesity-induced inflammation
    • Haase, J., Weyer, U., Immig, K., et al. (2014). Local proliferation of macrophages in adipose tissue during obesity-induced inflammation. Diabetologia 57, 562-571.
    • (2014) Diabetologia , vol.57 , pp. 562-571
    • Haase, J.1    Weyer, U.2    Immig, K.3
  • 8
    • 84873596150 scopus 로고    scopus 로고
    • Macrophage microvesicles induce macrophage differentiation and miR-223 transfer
    • Ismail, N., Wang, Y., Dakhlallah, D., et al. (2013). Macrophage microvesicles induce macrophage differentiation and miR-223 transfer. Blood 121, 984-995.
    • (2013) Blood , vol.121 , pp. 984-995
    • Ismail, N.1    Wang, Y.2    Dakhlallah, D.3
  • 9
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarization and insulin sensitivity
    • Kang, K., Reilly, S.M., Karabacak, V., et al. (2008). Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarization and insulin sensitivity. Cell Metab. 7, 485-495.
    • (2008) Cell Metab. , vol.7 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3
  • 10
    • 84899927111 scopus 로고    scopus 로고
    • Human adipocyte extracellular vesicles in reciprocal signaling between adipocytes and macrophages
    • Kranendonk, M.E., Visseren, F.L., van Balkom, B.W., et al. (2014). Human adipocyte extracellular vesicles in reciprocal signaling between adipocytes and macrophages. Obesity 22, 1296-1308.
    • (2014) Obesity , vol.22 , pp. 1296-1308
    • Kranendonk, M.E.1    Visseren, F.L.2    Van Balkom, B.W.3
  • 11
    • 80355146399 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage polarization: Enabling diversity with identity
    • Lawrence, T. and Natoli, G. (2011). Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat. Rev. Immunol. 11, 750-761.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 750-761
    • Lawrence, T.1    Natoli, G.2
  • 12
    • 84867569522 scopus 로고    scopus 로고
    • Argonaute 2 complexes selectively protect the circulating microRNAs in cell-secreted microvesicles
    • Li, L., Zhu, D., Huang, L., et al. (2012). Argonaute 2 complexes selectively protect the circulating microRNAs in cell-secreted microvesicles. PLoS One 7, e46957.
    • (2012) PLoS One , vol.7
    • Li, L.1    Zhu, D.2    Huang, L.3
  • 13
    • 84937706626 scopus 로고    scopus 로고
    • A single miRNA-mRNA interaction affects the immune response in a context- and cell-type-specific manner
    • Lu, L.F., Gasteiger, G., Yu, I.S., et al. (2015). A single miRNA-mRNA interaction affects the immune response in a context- and cell-type-specific manner. Immunity 43, 52-64.
    • (2015) Immunity , vol.43 , pp. 52-64
    • Lu, L.F.1    Gasteiger, G.2    Yu, I.S.3
  • 14
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng, C.N., Bodzin, J.L. and Saltiel, A.R. (2007). Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J. Clin. Invest. 117, 175-184.
    • (2007) J. Clin. Invest. , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 15
    • 58149347227 scopus 로고    scopus 로고
    • Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
    • Lumeng, C.N., DelProposto, J.B., Westcott, D.J., et al. (2008). Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes 57, 3239-3246.
    • (2008) Diabetes , vol.57 , pp. 3239-3246
    • Lumeng, C.N.1    DelProposto, J.B.2    Westcott, D.J.3
  • 16
    • 51349169485 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 inhibits IFN-γ inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation
    • Madonna, S., Scarponi, C., De Pita, O., et al. (2008). Suppressor of cytokine signaling 1 inhibits IFN-γ inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation. FASEB J. 22, 3287-3297.
    • (2008) FASEB J. , vol.22 , pp. 3287-3297
    • Madonna, S.1    Scarponi, C.2    De Pita, O.3
  • 17
    • 78751483763 scopus 로고    scopus 로고
    • The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor α1 (IL13Rα1)
    • Martinez-Nunez, R.T., Louafi, F. and Sanchez-Elsner, T. (2011). The interleukin 13 (IL-13) pathway in human macrophages is modulated by microRNA-155 via direct targeting of interleukin 13 receptor α1 (IL13Rα1). J. Biol. Chem. 286, 1786-1794.
    • (2011) J. Biol. Chem. , vol.286 , pp. 1786-1794
    • Martinez-Nunez, R.T.1    Louafi, F.2    Sanchez-Elsner, T.3
  • 18
    • 79959216069 scopus 로고    scopus 로고
    • Adipose tissue macrophages: Phenotypic plasticity and diversity in lean and obese states
    • Morris, D.L., Singer, K. and Lumeng, C.N. (2011). Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states. Curr. Opin. Clin. Nutr. Metab. Care 14, 341-346.
    • (2011) Curr. Opin. Clin. Nutr. Metab. Care , vol.14 , pp. 341-346
    • Morris, D.L.1    Singer, K.2    Lumeng, C.N.3
  • 19
    • 79954424525 scopus 로고    scopus 로고
    • Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis
    • Muller, G., Schneider, M., Biemer-Daub, G., et al. (2011). Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis. Cell. Signal. 23, 1207-1223.
    • (2011) Cell. Signal. , vol.23 , pp. 1207-1223
    • Muller, G.1    Schneider, M.2    Biemer-Daub, G.3
  • 20
    • 18744371050 scopus 로고    scopus 로고
    • SOCS-1 participates in negative regulation of LPS responses
    • Nakagawa, R., Naka, T., Tsutsui, H., et al. (2002). SOCS-1 participates in negative regulation of LPS responses. Immunity 17, 677-687.
    • (2002) Immunity , vol.17 , pp. 677-687
    • Nakagawa, R.1    Naka, T.2    Tsutsui, H.3
  • 21
    • 66349137358 scopus 로고    scopus 로고
    • Inositol phosphatase SHIP1 is a primary target of miR-155
    • O'Connell, R.M., Chaudhuri, A.A., Rao, D.S., et al. (2009). Inositol phosphatase SHIP1 is a primary target of miR-155. Proc. Natl Acad. Sci. USA 106, 7113-7118.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 7113-7118
    • O'Connell, R.M.1    Chaudhuri, A.A.2    Rao, D.S.3
  • 22
    • 33846845071 scopus 로고    scopus 로고
    • MicroRNA-155 is induced during the macrophage inflammatory response
    • O'Connell, R.M., Taganov, K.D., Boldin, M.P., et al. (2007). MicroRNA-155 is induced during the macrophage inflammatory response. Proc. Natl Acad. Sci. USA 104, 1604-1609.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 1604-1609
    • O'Connell, R.M.1    Taganov, K.D.2    Boldin, M.P.3
  • 23
    • 77955415911 scopus 로고    scopus 로고
    • Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation
    • Ogawa, R., Tanaka, C., Sato, M., et al. (2010). Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation. Biochem. Biophys. Res. Commun. 398, 723-729.
    • (2010) Biochem. Biophys. Res. Commun. , vol.398 , pp. 723-729
    • Ogawa, R.1    Tanaka, C.2    Sato, M.3
  • 24
    • 77949881805 scopus 로고    scopus 로고
    • Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype
    • Ohashi, K., Parker, J.L., Ouchi, N., et al. (2010). Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype. J. Biol. Chem. 285, 6153-6160.
    • (2010) J. Biol. Chem. , vol.285 , pp. 6153-6160
    • Ohashi, K.1    Parker, J.L.2    Ouchi, N.3
  • 25
    • 0031308702 scopus 로고    scopus 로고
    • IL-4-induced STAT6 suppresses IFN-γ-stimulated STAT1-dependent transcription in mouse macrophages
    • Ohmori, Y. and Hamilton, T.A. (1997). IL-4-induced STAT6 suppresses IFN-γ-stimulated STAT1-dependent transcription in mouse macrophages. J. Immunol. 159, 5474-5482.
    • (1997) J. Immunol. , vol.159 , pp. 5474-5482
    • Ohmori, Y.1    Hamilton, T.A.2
  • 26
    • 84983050288 scopus 로고    scopus 로고
    • Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants
    • Ortega, F.J., Moreno, M., Mercader, J.M., et al. (2015). Inflammation triggers specific microRNA profiles in human adipocytes and macrophages and in their supernatants. Clin. Epigenetics 7, 49.
    • (2015) Clin. Epigenetics , vol.7 , pp. 49
    • Ortega, F.J.1    Moreno, M.2    Mercader, J.M.3
  • 27
    • 84866528687 scopus 로고    scopus 로고
    • SOCS3 deficiency promotes M1 macrophage polarization and inflammation
    • Qin, H., Holdbrooks, A.T., Liu, Y., et al. (2012). SOCS3 deficiency promotes M1 macrophage polarization and inflammation. J. Immunol. 189, 3439-3448.
    • (2012) J. Immunol. , vol.189 , pp. 3439-3448
    • Qin, H.1    Holdbrooks, A.T.2    Liu, Y.3
  • 28
    • 0346220288 scopus 로고    scopus 로고
    • Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes
    • Ruan, H., Zarnowski, M.J., Cushman, S.W., et al. (2003). Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes. J. Biol. Chem. 278, 47585-47593.
    • (2003) J. Biol. Chem. , vol.278 , pp. 47585-47593
    • Ruan, H.1    Zarnowski, M.J.2    Cushman, S.W.3
  • 29
    • 51349156218 scopus 로고    scopus 로고
    • Insulin sensitivity: Modulation by nutrients and inflammation
    • Schenk, S., Saberi, M. and Olefsky, J.M. (2008). Insulin sensitivity: modulation by nutrients and inflammation. J. Clin. Invest. 118, 2992-3002.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2992-3002
    • Schenk, S.1    Saberi, M.2    Olefsky, J.M.3
  • 30
    • 84874338428 scopus 로고    scopus 로고
    • Induction of microRNA resistance and secretion in differentiating human endometrial stromal cells
    • Shah, K.M., Webber, J., Carzaniga, R., et al. (2013). Induction of microRNA resistance and secretion in differentiating human endometrial stromal cells. J. Mol. Cell Biol. 5, 67-70.
    • (2013) J. Mol. Cell Biol. , vol.5 , pp. 67-70
    • Shah, K.M.1    Webber, J.2    Carzaniga, R.3
  • 31
    • 79955958973 scopus 로고    scopus 로고
    • Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers
    • Sierra-Filardi, E., Puig-Kroger, A., Blanco, F.J., et al. (2011). Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood 117, 5092-5101.
    • (2011) Blood , vol.117 , pp. 5092-5101
    • Sierra-Filardi, E.1    Puig-Kroger, A.2    Blanco, F.J.3
  • 32
    • 0030792590 scopus 로고    scopus 로고
    • A family of cytokine-inducible inhibitors of signalling
    • Starr, R., Willson, T.A., Viney, E.M., et al. (1997). A family of cytokine-inducible inhibitors of signalling. Nature 387, 917-921.
    • (1997) Nature , vol.387 , pp. 917-921
    • Starr, R.1    Willson, T.A.2    Viney, E.M.3
  • 33
    • 15844404509 scopus 로고    scopus 로고
    • Essential role of Stat6 in IL-4 signalling
    • Takeda, K., Tanaka, T., Shi, W., et al. (1996). Essential role of Stat6 in IL-4 signalling. Nature 380, 627-630.
    • (1996) Nature , vol.380 , pp. 627-630
    • Takeda, K.1    Tanaka, T.2    Shi, W.3
  • 34
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: Composition, biogenesis and function
    • Thery, C., Zitvogel, L. and Amigorena, S (2002). Exosomes: composition, biogenesis and function. Nat. Rev. Immunol 2, 569-579.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 569-579
    • Thery, C.1    Zitvogel, L.2    Amigorena, S.3
  • 35
    • 34147164049 scopus 로고    scopus 로고
    • Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites
    • Tsou, C.L., Peters, W., Si, Y., et al. (2007). Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J. Clin. Invest. 117, 902-909.
    • (2007) J. Clin. Invest. , vol.117 , pp. 902-909
    • Tsou, C.L.1    Peters, W.2    Si, Y.3
  • 36
    • 84903160226 scopus 로고    scopus 로고
    • Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions
    • Vojtech, L., Woo, S., Hughes, S., et al. (2014). Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions. Nucleic Acids Res. 42, 7290-7304.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 7290-7304
    • Vojtech, L.1    Woo, S.2    Hughes, S.3
  • 37
    • 84905656745 scopus 로고    scopus 로고
    • SOCS proteins in macrophage polarization and function
    • Wilson, H.M. (2014). SOCS proteins in macrophage polarization and function. Front. Immunol. 5, 357.
    • (2014) Front. Immunol. , vol.5 , pp. 357
    • Wilson, H.M.1
  • 38
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu, H., Barnes, G.T., Yang, Q., et al. (2003). Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112, 1821-1830.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 39
    • 77449092780 scopus 로고    scopus 로고
    • Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: Dissociation of adipocyte hypertrophy from inflammation
    • Yeop Han, C., Kargi, A.Y., Omer, M., et al. (2010). Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. Diabetes 59, 386-396.
    • (2010) Diabetes , vol.59 , pp. 386-396
    • Yeop Han, C.1    Kargi, A.Y.2    Omer, M.3
  • 40
    • 84896700643 scopus 로고    scopus 로고
    • Microvesicle-mediated delivery of transforming growth factor β1 siRNA for the suppression of tumor growth in mice
    • Zhang, Y., Li, L., Yu, J., et al. (2014). Microvesicle-mediated delivery of transforming growth factor β1 siRNA for the suppression of tumor growth in mice. Biomaterials 35, 4390-4400.
    • (2014) Biomaterials , vol.35 , pp. 4390-4400
    • Zhang, Y.1    Li, L.2    Yu, J.3
  • 41
    • 77954257796 scopus 로고    scopus 로고
    • Secreted monocytic miR-150 enhances targeted endothelial cell migration
    • Zhang, Y., Liu, D., Chen, X., et al. (2010). Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol. Cell 39, 133-144.
    • (2010) Mol. Cell , vol.39 , pp. 133-144
    • Zhang, Y.1    Liu, D.2    Chen, X.3
  • 42
    • 84931050696 scopus 로고    scopus 로고
    • Inflamed macrophage microvesicles induce insulin resistance in human adipocytes
    • Zhang, Y., Shi, L., Mei, H., et al. (2015). Inflamed macrophage microvesicles induce insulin resistance in human adipocytes. Nutr. Metab. 12, 21.
    • (2015) Nutr. Metab. , vol.12 , pp. 21
    • Zhang, Y.1    Shi, L.2    Mei, H.3
  • 43
    • 84951823798 scopus 로고    scopus 로고
    • Leptin deficiency shifts mast cells toward anti-inflammatory actions and protects mice from obesity and diabetes by polarizing M2 macrophages
    • Zhou, Y., Yu, X., Chen, H., et al. (2015). Leptin deficiency shifts mast cells toward anti-inflammatory actions and protects mice from obesity and diabetes by polarizing M2 macrophages. Cell Metab. 22, 1045-1058.
    • (2015) Cell Metab. , vol.22 , pp. 1045-1058
    • Zhou, Y.1    Yu, X.2    Chen, H.3


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