Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages

Cell Metabolism

Volumn 22, Issue 6, 2015, Pages 1045-1058

  Zhou, Yi ^a,b   Yu, Xueqing ^b   Chen, Huimei ^a,c   Sjöberg, Sara ^a   Roux, Joséphine ^a   Zhang, Lijun ^a   Ivoulsou, Al Habib ^a   Bensaid, Farid ^a   Liu, Cong Lin ^a   Liu, Jian ^a,d   Tordjman, Joan ^e,g   Clement, Karine ^e,g   Lee, Chih Hao ^f   Hotamisligil, Gokhan S ^f   Libby, Peter ^a   Shi, Guo Ping ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^d HEFEI UNIVERSITY OF TECHNOLOGY   (China)

^e CENTRE DE RECHERCHE DES CORDELIERS   (France)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^g UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LEPTIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL POLARITY; CONTROLLED STUDY; DIABETES MELLITUS; EX VIVO STUDY; GLUCOSE INTOLERANCE; HUMAN; INTRACELLULAR SIGNALING; LEPTIN DEFICIENCY; MACROPHAGE; MAST CELL; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; WEIGHT GAIN; WHITE ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; DEFICIENCY; MOUSE MUTANT;

ANIMALS; DIABETES MELLITUS; HUMANS; LEPTIN; MACROPHAGES; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, OBESE; OBESITY;

EID: 84951823798     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.09.013     Document Type: Article

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