-
1
-
-
80355131976
-
Protective and pathogenic functions of macrophage subsets
-
doi: 10.1038/nri3073
-
Murray PJ, Wynn TA. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol (2011) 11:723-37. doi: 10.1038/nri3073
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 723-737
-
-
Murray, P.J.1
Wynn, T.A.2
-
2
-
-
0034659784
-
M-1/M-2 macrophages and the Th1/Th2 paradigm
-
doi:10.4049/jimmunol.164.12.6166
-
Mills CD, Kincaid K, Alt JM, Heilman MJ, Hill AM. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol (2000) 164:6166-73. doi:10.4049/jimmunol.164.12.6166
-
(2000)
J Immunol
, vol.164
, pp. 6166-6173
-
-
Mills, C.D.1
Kincaid, K.2
Alt, J.M.3
Heilman, M.J.4
Hill, A.M.5
-
3
-
-
84857883847
-
Macrophage plasticity and polarization: in vivo veritas.
-
doi:10.1172/JCI59643
-
Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 122:787-95. doi:10.1172/JCI59643
-
(2012)
J Clin Invest
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
4
-
-
80055096913
-
Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function.
-
doi:10.1189/jlb.1110644
-
Whyte CS, Bishop ET, Rückerl D, Gaspar-Pereira S, Barker RN, Allen JE, et al. Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function. J Leukoc Biol (2011) 90:845-54. doi:10.1189/jlb.1110644
-
(2011)
J Leukoc Biol
, vol.90
, pp. 845-854
-
-
Whyte, C.S.1
Bishop, E.T.2
Rückerl, D.3
Gaspar-Pereira, S.4
Barker, R.N.5
Allen, J.E.6
-
5
-
-
44449140105
-
Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo.
-
doi:10.4049/jimmunol.180.9.6270
-
Liu Y, Stewart KN, Bishop ET, Marek CM, Kluth DC, Rees AJ, et al. Unique expression of suppressor of cytokine signaling 3 is essential for classical macrophage activation in rodents in vitro and in vivo. J Immunol (2008) 180:6270-8. doi:10.4049/jimmunol.180.9.6270
-
(2008)
J Immunol
, vol.180
, pp. 6270-6278
-
-
Liu, Y.1
Stewart, K.N.2
Bishop, E.T.3
Marek, C.M.4
Kluth, D.C.5
Rees, A.J.6
-
6
-
-
84889632645
-
A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and function in vitro and in vivo.
-
doi:10.1111/imm.12173
-
Arnold CE, Whyte CS, Gordon P, Barker RN, Rees AJ, Wilson HM. A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and function in vitro and in vivo. Immunology (2014) 141:96-110. doi:10.1111/imm.12173
-
(2014)
Immunology
, vol.141
, pp. 96-110
-
-
Arnold, C.E.1
Whyte, C.S.2
Gordon, P.3
Barker, R.N.4
Rees, A.J.5
Wilson, H.M.6
-
7
-
-
84866528687
-
SOCS3 deficiency promotes M1 macrophage polarization and inflammation.
-
doi:10.4049/jimmunol.1201168
-
Qin H, Holdbrooks AT, Liu Y, Reynolds SL, Yanagisawa LL, Benveniste EN. SOCS3 deficiency promotes M1 macrophage polarization and inflammation. J Immunol (2012) 189:3439-48. doi:10.4049/jimmunol.1201168
-
(2012)
J Immunol
, vol.189
, pp. 3439-3448
-
-
Qin, H.1
Holdbrooks, A.T.2
Liu, Y.3
Reynolds, S.L.4
Yanagisawa, L.L.5
Benveniste, E.N.6
-
8
-
-
84859260924
-
Suppressor of cytokine signaling proteins as regulators of innate immune signaling
-
Strebovsky J, Walker P, Dalpke AH. Suppressor of cytokine signaling proteins as regulators of innate immune signaling. Front Biosci (2012) 17:1627-39.
-
(2012)
Front Biosci
, vol.17
, pp. 1627-1639
-
-
Strebovsky, J.1
Walker, P.2
Dalpke, A.H.3
-
9
-
-
34249660614
-
SOCS proteins, cytokine signaling, and immune regulation
-
doi:10.1038/nri2093
-
Yoshimura A, Naka T, Kubo M. SOCS proteins, cytokine signaling, and immune regulation. Nat Rev Immunol (2007) 7:454-65. doi:10.1038/nri2093
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 454-465
-
-
Yoshimura, A.1
Naka, T.2
Kubo, M.3
-
10
-
-
51349169485
-
Suppressor of cytokine signaling 1 inhibits IFN-gamma inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation.
-
doi:10.1096/fj.08-106831
-
Madonna S, Scarponi C, De Pità O, Albanesi C. Suppressor of cytokine signaling 1 inhibits IFN-gamma inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation. FASEB J (2008) 22:3287-97. doi:10.1096/fj.08-106831
-
(2008)
FASEB J
, vol.22
, pp. 3287-3297
-
-
Madonna, S.1
Scarponi, C.2
De Pità, O.3
Albanesi, C.4
-
11
-
-
33845992917
-
Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to pro-apoptotic.
-
doi:10.1074/jbc.M607374200
-
Lu Y, Fukuyama S, Yoshida R, Kobayashi T, Saeki K, Shiraishi H, et al. Loss of SOCS3 gene expression converts STAT3 function from anti-apoptotic to pro-apoptotic. J Biol Chem (2006) 281:36683-90. doi:10.1074/jbc.M607374200
-
(2006)
J Biol Chem
, vol.281
, pp. 36683-36690
-
-
Lu, Y.1
Fukuyama, S.2
Yoshida, R.3
Kobayashi, T.4
Saeki, K.5
Shiraishi, H.6
-
12
-
-
77953752609
-
Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses.
-
doi:10.1158/0008-5472.CAN-10-0269
-
Wang YC, He F, Feng F, Liu XW, Dong GY, Qin HY. Notch signaling determines the M1 versus M2 polarization of macrophages in antitumor immune responses. Cancer Res (2010) 70:4840-9. doi:10.1158/0008-5472.CAN-10-0269
-
(2010)
Cancer Res
, vol.70
, pp. 4840-4849
-
-
Wang, Y.C.1
He, F.2
Feng, F.3
Liu, X.W.4
Dong, G.Y.5
Qin, H.Y.6
-
13
-
-
77953565270
-
SOCS-3 antagonises the proliferative and migratory effects of fibroblast growth factor-2 in prostate cancer by inhibition of p44/p42 MAPK signalling.
-
doi:10.1677/ERC-10-0007
-
Puhr M, Santer FR, Neuwirt H, Marcias G, Hobisch A, Culig Z. SOCS-3 antagonises the proliferative and migratory effects of fibroblast growth factor-2 in prostate cancer by inhibition of p44/p42 MAPK signalling. Endocr Relat Cancer (2010) 17:525-38. doi:10.1677/ERC-10-0007
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. 525-538
-
-
Puhr, M.1
Santer, F.R.2
Neuwirt, H.3
Marcias, G.4
Hobisch, A.5
Culig, Z.6
-
14
-
-
18744371050
-
SOCS-1 participates in negative regulation of LPS responses.
-
doi:10.1016/S1074-7613(02)00449-1
-
Nakagawa R, Naka T, Tsutsui H, Fujimoto M, Kimura A, Abe T, et al. SOCS-1 participates in negative regulation of LPS responses. Immunity (2002) 17:677-87. doi:10.1016/S1074-7613(02)00449-1
-
(2002)
Immunity
, vol.17
, pp. 677-687
-
-
Nakagawa, R.1
Naka, T.2
Tsutsui, H.3
Fujimoto, M.4
Kimura, A.5
Abe, T.6
-
15
-
-
0347955360
-
Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.
-
doi:10.1016/S1097-2765(03)00490-8
-
Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, Wulf G, et al. Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol Cell (2003) 12:1413-26. doi:10.1016/S1097-2765(03)00490-8
-
(2003)
Mol Cell
, vol.12
, pp. 1413-1426
-
-
Ryo, A.1
Suizu, F.2
Yoshida, Y.3
Perrem, K.4
Liou, Y.C.5
Wulf, G.6
-
16
-
-
0036850946
-
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation.
-
doi:10.1016/S1074-7613(02)00446-6
-
Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, et al. SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity (2002) 17:583-91. doi:10.1016/S1074-7613(02)00446-6
-
(2002)
Immunity
, vol.17
, pp. 583-591
-
-
Kinjyo, I.1
Hanada, T.2
Inagaki-Ohara, K.3
Mori, H.4
Aki, D.5
Ohishi, M.6
-
17
-
-
80052848442
-
Macrophage deletion of SOCS1 increases sensitivity to LPS and palmitic acid and results in systemic inflammation and hepatic insulin resistance.
-
doi:10.2337/db11-0259
-
Sachithanandan N, Graham KL, Galic S, Honeyman JE, Fynch SL, Hewitt KA, et al. Macrophage deletion of SOCS1 increases sensitivity to LPS and palmitic acid and results in systemic inflammation and hepatic insulin resistance. Diabetes (2011) 60:2023-31. doi:10.2337/db11-0259
-
(2011)
Diabetes
, vol.60
, pp. 2023-2031
-
-
Sachithanandan, N.1
Graham, K.L.2
Galic, S.3
Honeyman, J.E.4
Fynch, S.L.5
Hewitt, K.A.6
-
18
-
-
11144233242
-
Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells.
-
doi:10.1074/jbc.M410992200
-
Baetz A, Frey M, Heeg K, Dalpke AH. Suppressor of cytokine signaling (SOCS) proteins indirectly regulate toll-like receptor signaling in innate immune cells. J Biol Chem (2004) 279:54708-15. doi:10.1074/jbc.M410992200
-
(2004)
J Biol Chem
, vol.279
, pp. 54708-54715
-
-
Baetz, A.1
Frey, M.2
Heeg, K.3
Dalpke, A.H.4
-
19
-
-
11144224785
-
Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling.
-
doi:10.1074/jbc.M411043200
-
Gingras S, Parganas E, de Pauw A, Ihle JN, Murray PJ. Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling. J Biol Chem (2004) 279:54702-7. doi:10.1074/jbc.M411043200
-
(2004)
J Biol Chem
, vol.279
, pp. 54702-54707
-
-
Gingras, S.1
Parganas, E.2
de Pauw, A.3
Ihle, J.N.4
Murray, P.J.5
-
20
-
-
84894055321
-
SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages.
-
doi:10.1016/j.toxlet.2013.12.023
-
Cheng C, Huang C, Ma TT, Bian EB, He Y, Zhang L, et al. SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages. Toxicol Lett (2014) 225:488-97. doi:10.1016/j.toxlet.2013.12.023
-
(2014)
Toxicol Lett
, vol.225
, pp. 488-497
-
-
Cheng, C.1
Huang, C.2
Ma, T.T.3
Bian, E.B.4
He, Y.5
Zhang, L.6
-
21
-
-
33846845071
-
MicroRNA-155 is induced during the macrophage inflammatory response.
-
doi:10.1073/pnas.0610731104
-
O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D. MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci U S A (2007) 104:1604-9. doi:10.1073/pnas.0610731104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1604-1609
-
-
O'Connell, R.M.1
Taganov, K.D.2
Boldin, M.P.3
Cheng, G.4
Baltimore, D.5
-
22
-
-
70349323601
-
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages.
-
doi:10.1096/fj.09-131342
-
Ruggiero T, Trabucchi M, De Santa F, Zupo S, Harfe BD, McManus MT, et al. LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J (2009) 23:2898-908. doi:10.1096/fj.09-131342
-
(2009)
FASEB J
, vol.23
, pp. 2898-2908
-
-
Ruggiero, T.1
Trabucchi, M.2
De Santa, F.3
Zupo, S.4
Harfe, B.D.5
McManus, M.T.6
-
23
-
-
68649091506
-
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs.
-
doi:10.1016/j.immuni.2009.06.024
-
Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, Zacharioudaki V. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity (2009) 31:220-31. doi:10.1016/j.immuni.2009.06.024
-
(2009)
Immunity
, vol.31
, pp. 220-231
-
-
Androulidaki, A.1
Iliopoulos, D.2
Arranz, A.3
Doxaki, C.4
Schworer, S.5
Zacharioudaki, V.6
-
24
-
-
2942592246
-
Enhancer-mediated control of macrophage-specific arginase I expression.
-
doi:10.4049/jimmunol.172.12.7565
-
Pauleau AL, Rutschman R, Lang R, Pernis A, Watowich SS, Murray PJ. Enhancer-mediated control of macrophage-specific arginase I expression. J Immunol (2004) 172:7565-73. doi:10.4049/jimmunol.172.12.7565
-
(2004)
J Immunol
, vol.172
, pp. 7565-7573
-
-
Pauleau, A.L.1
Rutschman, R.2
Lang, R.3
Pernis, A.4
Watowich, S.S.5
Murray, P.J.6
-
25
-
-
4143102310
-
LPS-induced upregulation of SHIP is essential for endotoxin tolerance.
-
doi:10.1016/j.immuni.2004.07.010
-
Sly LM, Rauh MJ, Kalesnikoff J, Song CH, Krystal G. LPS-induced upregulation of SHIP is essential for endotoxin tolerance. Immunity (2004) 21:227-39. doi:10.1016/j.immuni.2004.07.010
-
(2004)
Immunity
, vol.21
, pp. 227-239
-
-
Sly, L.M.1
Rauh, M.J.2
Kalesnikoff, J.3
Song, C.H.4
Krystal, G.5
-
26
-
-
33846523494
-
Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling.
-
doi:10.1038/sj.gene.6364352
-
Dickensheets HN, Vazquez N, Sheikh F, Gingras S, Murray PJ, Ryan JJ, et al. Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling. Genes Immun (2007) 8:21-7. doi:10.1038/sj.gene.6364352
-
(2007)
Genes Immun
, vol.8
, pp. 21-27
-
-
Dickensheets, H.N.1
Vazquez, N.2
Sheikh, F.3
Gingras, S.4
Murray, P.J.5
Ryan, J.J.6
-
27
-
-
34249823656
-
Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3.
-
doi:10.4049/jimmunol.178.11.6886
-
O'Connor JC, Sherry CL, Guest CB, Freund GG. Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3. J Immunol (2007) 178:6886-93. doi:10.4049/jimmunol.178.11.6886
-
(2007)
J Immunol
, vol.178
, pp. 6886-6893
-
-
O'Connor, J.C.1
Sherry, C.L.2
Guest, C.B.3
Freund, G.G.4
-
28
-
-
66349084135
-
Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis.
-
doi:10.1371/journal.ppat.1000371
-
Pesce JT, Ramalingam TR, Mentink-Kane MM, Wilson MS, El Kasmi KC, Smith AM, et al. Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis. PLoS Pathog (2009) 5:e1000371. doi:10.1371/journal.ppat.1000371
-
(2009)
PLoS Pathog
, vol.5
-
-
Pesce, J.T.1
Ramalingam, T.R.2
Mentink-Kane, M.M.3
Wilson, M.S.4
El Kasmi, K.C.5
Smith, A.M.6
-
29
-
-
84862669208
-
Role of SOCS2 in modulating heart damage and function in a murine model of acute Chagas disease.
-
doi:10.1016/j.ajpath.2012.03.042
-
Esper L, Roman-Campos D, Lara A, Brant F, Castro LL, Barroso A, et al. Role of SOCS2 in modulating heart damage and function in a murine model of acute Chagas disease. Am J Pathol (2012) 181:130-40. doi:10.1016/j.ajpath.2012.03.042
-
(2012)
Am J Pathol
, vol.181
, pp. 130-140
-
-
Esper, L.1
Roman-Campos, D.2
Lara, A.3
Brant, F.4
Castro, L.L.5
Barroso, A.6
-
30
-
-
84864665833
-
In SOCS2 KO mice, there was a reduction in both parasitemia and the expression of interferon-g (IFN-g), tumor necrosis factor-a (TNF-a), IL-6, IL-10, SOCS1, and SOCS3 in the spleen
-
doi:10.1096/fj.12-205583
-
Zadjali F, Santana-Farre R, Vesterlund M, Carow B, Mirecki-Garrido M, Hernandez-Hernandez I, et al. In SOCS2 KO mice, there was a reduction in both parasitemia and the expression of interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), IL-6, IL-10, SOCS1, and SOCS3 in the spleen. FASEB J (2012) 26:3282-91. doi:10.1096/fj.12-205583
-
(2012)
FASEB J
, vol.26
, pp. 3282-3291
-
-
Zadjali, F.1
Santana-Farre, R.2
Vesterlund, M.3
Carow, B.4
Mirecki-Garrido, M.5
Hernandez-Hernandez, I.6
-
31
-
-
80053086471
-
Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells.
-
doi:10.4049/jimmunol.1003348
-
Posselt G, Schwarz H, Duschl A, Horejs-Hoeck J. Suppressor of cytokine signaling 2 is a feedback inhibitor of TLR-induced activation in human monocyte-derived dendritic cells. J Immunol (2011) 187:2875-84. doi:10.4049/jimmunol.1003348
-
(2011)
J Immunol
, vol.187
, pp. 2875-2884
-
-
Posselt, G.1
Schwarz, H.2
Duschl, A.3
Horejs-Hoeck, J.4
-
32
-
-
80052997034
-
A critical role for SOCS3 in innate resistance to Toxoplasma gondii.
-
doi:10.1016/j.chom.2011.07.009
-
Whitmarsh RJ, Gray CM, Gregg B, Christian DA, May MJ, Murray PJ, et al. A critical role for SOCS3 in innate resistance to Toxoplasma gondii. Cell Host Microbe (2011) 10:224-36. doi:10.1016/j.chom.2011.07.009
-
(2011)
Cell Host Microbe
, vol.10
, pp. 224-236
-
-
Whitmarsh, R.J.1
Gray, C.M.2
Gregg, B.3
Christian, D.A.4
May, M.J.5
Murray, P.J.6
-
33
-
-
0038614944
-
SOCS3 regulates the plasticity of gp130 signaling.
-
doi:10.1038/ni932
-
Lang R, Pauleau AL, Parganas E, Takahashi Y, Mages J, Ihle JN. SOCS3 regulates the plasticity of gp130 signaling. Nat Immunol (2003) 4:546-50. doi:10.1038/ni932
-
(2003)
Nat Immunol
, vol.4
, pp. 546-550
-
-
Lang, R.1
Pauleau, A.L.2
Parganas, E.3
Takahashi, Y.4
Mages, J.5
Ihle, J.N.6
-
34
-
-
0037938816
-
Negatively regulates IL-6 signaling in vivo.
-
doi:10.1038/ni931
-
Croker BA, Krebs DL, Zhang JG, Wormald S, Willson TA, Stanley EG, et al. Negatively regulates IL-6 signaling in vivo. Nat Immunol (2003) 4:540-5. doi:10.1038/ni931
-
(2003)
Nat Immunol
, vol.4
, pp. 540-545
-
-
Croker, B.A.1
Krebs, D.L.2
Zhang, J.G.3
Wormald, S.4
Willson, T.A.5
Stanley, E.G.6
-
35
-
-
0037600741
-
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages.
-
doi:10.1038/ni938
-
Yasukawa H, Ohishi M, Mori H, Murakami M, Chinen T, Aki D. IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nat Immunol (2003) 4:551-6. doi:10.1038/ni938
-
(2003)
Nat Immunol
, vol.4
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
Murakami, M.4
Chinen, T.5
Aki, D.6
-
36
-
-
37349112666
-
SOCS3 promotes TLR4 response in macrophages by feedback inhibiting TGF-beta1/Smad3 signaling.
-
doi:10.1016/j.molimm.2007.08.018
-
Liu X, Zhang Y, Yu Y, Yang X, Cao X. SOCS3 promotes TLR4 response in macrophages by feedback inhibiting TGF-beta1/Smad3 signaling. Mol Immunol (2008) 45:1405-13. doi:10.1016/j.molimm.2007.08.018
-
(2008)
Mol Immunol
, vol.45
, pp. 1405-1413
-
-
Liu, X.1
Zhang, Y.2
Yu, Y.3
Yang, X.4
Cao, X.5
-
37
-
-
79959567446
-
Suppression of SOCS3 in macrophages prevents cancer metastasis by modifying macrophage phase and MCP2/CCL8 induction.
-
doi:10.1016/j.canlet.2011.04.024
-
Hiwatashi K, Tamiya T, Hasegawa E, Fukaya T, Hashimoto M, Kakoi K, et al. Suppression of SOCS3 in macrophages prevents cancer metastasis by modifying macrophage phase and MCP2/CCL8 induction. Cancer Lett (2011) 308:172-80. doi:10.1016/j.canlet.2011.04.024
-
(2011)
Cancer Lett
, vol.308
, pp. 172-180
-
-
Hiwatashi, K.1
Tamiya, T.2
Hasegawa, E.3
Fukaya, T.4
Hashimoto, M.5
Kakoi, K.6
-
38
-
-
34848898431
-
Selective expansion of foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells.
-
doi:10.4049/jimmunol.179.4.2170
-
Matsumura Y, Kobayashi T, Ichiyama K, Yoshida R, Hashimoto M, Takimoto T, et al. Selective expansion of foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells. J Immunol (2007) 179:2170-9. doi:10.4049/jimmunol.179.4.2170
-
(2007)
J Immunol
, vol.179
, pp. 2170-2179
-
-
Matsumura, Y.1
Kobayashi, T.2
Ichiyama, K.3
Yoshida, R.4
Hashimoto, M.5
Takimoto, T.6
-
39
-
-
84859473951
-
Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation.
-
doi:10.1073/pnas.1117218109
-
Qin H, Yeh WI, De Sarno P, Holdbrooks AT, Liu Y, Muldowney MT, et al. Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation. Proc Natl Acad Sci U S A (2012) 109:5004-9. doi:10.1073/pnas.1117218109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 5004-5009
-
-
Qin, H.1
Yeh, W.I.2
De Sarno, P.3
Holdbrooks, A.T.4
Liu, Y.5
Muldowney, M.T.6
-
40
-
-
33745190069
-
SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis.
-
doi:10.1172/JCI25660
-
Wong PK, Egan PJ, Croker BA, O'Donnell K, Sims NA, Drake S, et al. SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis. J Clin Invest (2006) 116:1571-81. doi:10.1172/JCI25660
-
(2006)
J Clin Invest
, vol.116
, pp. 1571-1581
-
-
Wong, P.K.1
Egan, P.J.2
Croker, B.A.3
O'Donnell, K.4
Sims, N.A.5
Drake, S.6
-
41
-
-
63449106571
-
Suppressors of cytokine signalling modulate JAK/STAT-mediated cell responses during atherosclerosis.
-
doi:10.1161/ATVBAHA.108.173781
-
Ortiz-Munoz G, Martin-Ventura JL, Hernandez-Vargas P, Mallavia B, Lopez-Parra V, Lopes-Franco O, et al. Suppressors of cytokine signalling modulate JAK/STAT-mediated cell responses during atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 29:525-31. doi:10.1161/ATVBAHA.108.173781
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 525-531
-
-
Ortiz-Munoz, G.1
Martin-Ventura, J.L.2
Hernandez-Vargas, P.3
Mallavia, B.4
Lopez-Parra, V.5
Lopes-Franco, O.6
-
42
-
-
24044434247
-
The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice.
-
doi:10.1016/S0002-9440(10)62061-5
-
Tang J, Kozaki K, Farr AG, Martin PJ, Lindahl P, Betsholtz C, et al. The absence of platelet-derived growth factor-B in circulating cells promotes immune and inflammatory responses in atherosclerosis-prone ApoE-/- mice. Am J Pathol (2005) 167:901-12. doi:10.1016/S0002-9440(10)62061-5
-
(2005)
Am J Pathol
, vol.167
, pp. 901-912
-
-
Tang, J.1
Kozaki, K.2
Farr, A.G.3
Martin, P.J.4
Lindahl, P.5
Betsholtz, C.6
-
43
-
-
84867746307
-
Macrophage subtypes in symptomatic carotid artery and femoral artery plaques.
-
doi:10.1016/j.ejvs.2012.08.005
-
Shaikh S, Brittenden J, Lahiri R, Brown PA, Thies F, Wilson HM. Macrophage subtypes in symptomatic carotid artery and femoral artery plaques. Eur J Vasc Endovasc Surg (2012) 44:491-7. doi:10.1016/j.ejvs.2012.08.005
-
(2012)
Eur J Vasc Endovasc Surg
, vol.44
, pp. 491-497
-
-
Shaikh, S.1
Brittenden, J.2
Lahiri, R.3
Brown, P.A.4
Thies, F.5
Wilson, H.M.6
-
44
-
-
84871644701
-
Role of suppressor of cytokine signaling-1 in murine atherosclerosis.
-
doi:10.1371/journal.pone.0051608
-
Grothusen C, Schuett H, Hillmer A, Lumpe S, Grote K, Ballmaier M. Role of suppressor of cytokine signaling-1 in murine atherosclerosis. PLoS One (2012) 7:e51608. doi:10.1371/journal.pone.0051608
-
(2012)
PLoS One
, vol.7
-
-
Grothusen, C.1
Schuett, H.2
Hillmer, A.3
Lumpe, S.4
Grote, K.5
Ballmaier, M.6
-
45
-
-
49849106258
-
Lacking the SOCS3 Gene in macrophages prevents the development of atherosclerosis in ApoE deficient mice.
-
Yamamoto TYH, Koga M. Lacking the SOCS3 Gene in macrophages prevents the development of atherosclerosis in ApoE deficient mice. Circ J (2007) 71:170.
-
(2007)
Circ J
, vol.71
, pp. 170
-
-
Yamamoto, T.Y.H.1
Koga, M.2
-
46
-
-
84861660536
-
SOCS3 in immune regulation of inflammatory bowel disease and inflammatory bowel disease-related cancer.
-
doi:10.1016/j.cytogfr.2012.04.005
-
Li Y, de Haar C, Peppelenbosch MP, van der Woude CJ. SOCS3 in immune regulation of inflammatory bowel disease and inflammatory bowel disease-related cancer. Cytokine Growth Factor Rev (2012) 23:127-38. doi:10.1016/j.cytogfr.2012.04.005
-
(2012)
Cytokine Growth Factor Rev
, vol.23
, pp. 127-138
-
-
Li, Y.1
de Haar, C.2
Peppelenbosch, M.P.3
van der Woude, C.J.4
-
47
-
-
79955110851
-
Immunoregulatory mechanisms of macrophage PPAR-g in mice with experimental inflammatory bowel disease.
-
doi:10.1038/mi.2010.75
-
Hontecillas R, Horne WT, Climent M, Guri AJ, Evans C, Zhang Y. Immunoregulatory mechanisms of macrophage PPAR-γ in mice with experimental inflammatory bowel disease. Mucosal Immunol (2011) 4:304-13. doi:10.1038/mi.2010.75
-
(2011)
Mucosal Immunol
, vol.4
, pp. 304-313
-
-
Hontecillas, R.1
Horne, W.T.2
Climent, M.3
Guri, A.J.4
Evans, C.5
Zhang, Y.6
-
48
-
-
84866535934
-
Characterisation of tumour-infiltrating macrophages: impact on response and survival in patients receiving primary chemotherapy for breast cancer.
-
doi:10.1007/s10549-012-2190-6
-
Heys SD, Stewart KN, McKenzie EJ, Miller ID, Wong SY, Sellar G, et al. Characterisation of tumour-infiltrating macrophages: impact on response and survival in patients receiving primary chemotherapy for breast cancer. Breast Cancer Res Treat (2009) 135:539-48. doi:10.1007/s10549-012-2190-6
-
(2009)
Breast Cancer Res Treat
, vol.135
, pp. 539-548
-
-
Heys, S.D.1
Stewart, K.N.2
McKenzie, E.J.3
Miller, I.D.4
Wong, S.Y.5
Sellar, G.6
-
49
-
-
67449083552
-
Silencing of SOCS1 in macrophages suppresses tumor development by enhancing antitumor inflammation.
-
doi:10.1111/j.1349-7006.2009.01098.x
-
Hashimoto M, Ayada T, Kinjyo I, Hiwatashi K, Yoshida H, Okada Y, et al. Silencing of SOCS1 in macrophages suppresses tumor development by enhancing antitumor inflammation. Cancer Sci (2009) 100:730-6. doi:10.1111/j.1349-7006.2009.01098.x
-
(2009)
Cancer Sci
, vol.100
, pp. 730-736
-
-
Hashimoto, M.1
Ayada, T.2
Kinjyo, I.3
Hiwatashi, K.4
Yoshida, H.5
Okada, Y.6
-
50
-
-
80054987077
-
Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production
-
doi:10.1002/jcb.23267
-
Scheller EL, Hankenson KD, Reuben JS, Krebsbach PH. Zoledronic acid inhibits macrophage SOCS3 expression and enhances cytokine production. J Cell Biochem (2011) 112:3364-72. doi:10.1002/jcb.23267
-
(2011)
J Cell Biochem
, vol.112
, pp. 3364-3372
-
-
Scheller, E.L.1
Hankenson, K.D.2
Reuben, J.S.3
Krebsbach, P.H.4
|