Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

Nature Communications

Volumn 8, Issue , 2017, Pages

  Ferry, Quentin R V ^a   Lyutova, Radostina ^a   Fulga, Tudor A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; GUIDE RNA; RIBOZYME; SINGLE GUIDE RNA; SINGLE STRANDED DNA; SYNTHETIC DNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; LIGAND;

BIOLOGY; CELLS AND CELL COMPONENTS; GENE; GENE EXPRESSION; GENETIC MARKER; MAMMAL; PROTEIN; RNA;

ARTICLE; BASE PAIRING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COMPARATIVE STUDY; CONTROLLED STUDY; DE NOVO ASSEMBLY; GENE ACTIVATION; GENE FUNCTION; GENE STRUCTURE; GENE TARGETING; GENETIC CODE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN SECONDARY STRUCTURE; PSEUDOMONAS AERUGINOSA; REPORTER GENE; RNA CLEAVAGE; RNA SEQUENCE; ALGORITHM; EVALUATION STUDY; FLOW CYTOMETRY; GENE REGULATORY NETWORK; GENE VECTOR; GENETIC ENGINEERING; GENETICS; HEK293 CELL LINE; PROCEDURES; TRANSCRIPTION INITIATION;

MAMMALIA;

ALGORITHMS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; FLOW CYTOMETRY; GENE REGULATORY NETWORKS; GENETIC ENGINEERING; GENETIC VECTORS; HEK293 CELLS; HUMANS; LIGANDS; RNA, GUIDE; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

EID: 85014514373     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14633     Document Type: Article

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