메뉴 건너뛰기




Volumn 28, Issue 4, 2017, Pages 1820-1827

Growth inhibitory effect of stevioside on ovarian cancer through Akt/ERK pathway

Author keywords

Apoptosis; Growth inhibition; Ovarian cancer; Signaling pathway; Stevioside

Indexed keywords

CASPASE 3; CASPASE 9; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STEVIOSIDE;

EID: 85014382972     PISSN: 0970938X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (8)

References (42)
  • 1
    • 0034909802 scopus 로고    scopus 로고
    • Advances in the management of epithelial ovarian cancer
    • Memarzadeh S, Berek JS. Advances in the management of epithelial ovarian cancer. J Reprod Med 2001; 46: 621-629.
    • (2001) J Reprod Med , vol.46 , pp. 621-629
    • Memarzadeh, S.1    Berek, J.S.2
  • 3
    • 60749137451 scopus 로고    scopus 로고
    • Beyond chemotherapy: Targeted therapies in ovarian cancer
    • Yap TA, Carden CP, Kaye SB. Beyond chemotherapy: targeted therapies in ovarian cancer. Nat Rev Cancer 2009; 9: 167-181.
    • (2009) Nat Rev Cancer , vol.9 , pp. 167-181
    • Yap, T.A.1    Carden, C.P.2    Kaye, S.B.3
  • 4
    • 67649440886 scopus 로고    scopus 로고
    • The biology of ovarian cancer: New opportunities for translation
    • Bast RC Jr, Hennessy B, Mills GB. The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer 2009; 9: 415-428.
    • (2009) Nat Rev Cancer , vol.9 , pp. 415-428
    • Bast, R.C.1    Hennessy, B.2    Mills, G.B.3
  • 5
    • 33646726747 scopus 로고    scopus 로고
    • Management of platinumsensitive recurrent ovarian cancer
    • Pfisterer J, Ledermann JA. Management of platinumsensitive recurrent ovarian cancer. Semin Oncol 2006; 33: S12-16.
    • (2006) Semin Oncol , vol.33 , pp. S12-S16
    • Pfisterer, J.1    Ledermann, J.A.2
  • 6
    • 0024522049 scopus 로고
    • Response of patients in phase II studies of chemotherapy in ovarian cancer: Implications for patient treatment and the design of phase II trials
    • Blackledge G, Lawton F, Redman C, Kelly K. Response of patients in phase II studies of chemotherapy in ovarian cancer: implications for patient treatment and the design of phase II trials. Br J Cancer 1989; 59: 650-653.
    • (1989) Br J Cancer , vol.59 , pp. 650-653
    • Blackledge, G.1    Lawton, F.2    Redman, C.3    Kelly, K.4
  • 7
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 2003; 3: 768-780.
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 8
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal BB, Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem Pharmacol 2006; 71: 1397-1421.
    • (2006) Biochem Pharmacol , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 9
    • 84858050384 scopus 로고    scopus 로고
    • Resveratrol downregulates Akt/GSK and ERK signalling pathways in OVCAR-3 ovarian cancer cells
    • Vergara D, Simeone P, Toraldo D, Del Boccio P, Vergaro V. Resveratrol downregulates Akt/GSK and ERK signalling pathways in OVCAR-3 ovarian cancer cells. Mol Biosyst 2012; 8: 1078-1087.
    • (2012) Mol Biosyst , vol.8 , pp. 1078-1087
    • Vergara, D.1    Simeone, P.2    Toraldo, D.3    Del Boccio, P.4    Vergaro, V.5
  • 10
    • 84931838411 scopus 로고    scopus 로고
    • Effect of quercetin on the proliferation of the human ovarian cancer cell line SKOV-3 in vitro
    • Ren MX, Deng XH, Ai F, Yuan GY, Song HY. Effect of quercetin on the proliferation of the human ovarian cancer cell line SKOV-3 in vitro. Exp Ther Med 2015; 10: 579-583.
    • (2015) Exp Ther Med , vol.10 , pp. 579-583
    • Ren, M.X.1    Deng, X.H.2    Ai, F.3    Yuan, G.Y.4    Song, H.Y.5
  • 11
    • 84928580755 scopus 로고    scopus 로고
    • The flavonoid nobiletin inhibits tumor growth and angiogenesis of ovarian cancers via the Akt pathway
    • Chen J, Chen AY, Huang H, Ye X, Rollyson WD. The flavonoid nobiletin inhibits tumor growth and angiogenesis of ovarian cancers via the Akt pathway. Int J Oncol 2015; 46: 2629-2638.
    • (2015) Int J Oncol , vol.46 , pp. 2629-2638
    • Chen, J.1    Chen, A.Y.2    Huang, H.3    Ye, X.4    Rollyson, W.D.5
  • 12
    • 4444307804 scopus 로고    scopus 로고
    • Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines
    • Huh SW, Bae SM, Kim YW, Lee JM, Namkoong SE. Anticancer effects of (-)-epigallocatechin-3-gallate on ovarian carcinoma cell lines. Gynecol Oncol 2004; 94: 760-768.
    • (2004) Gynecol Oncol , vol.94 , pp. 760-768
    • Huh, S.W.1    Bae, S.M.2    Kim, Y.W.3    Lee, J.M.4    Namkoong, S.E.5
  • 13
    • 79955598035 scopus 로고    scopus 로고
    • Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway
    • Luo H, Rankin GO, Li Z, Depriest L, Chen YC. Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway. Food Chem 2011; 128: 513-519.
    • (2011) Food Chem , vol.128 , pp. 513-519
    • Luo, H.1    Rankin, G.O.2    Li, Z.3    Depriest, L.4    Chen, Y.C.5
  • 14
    • 84916613631 scopus 로고    scopus 로고
    • Apigenin inhibits the self-renewal capacity of human ovarian cancer SKOV3derived sphere-forming cells
    • Tang AQ, Cao XC, Tian L, He L, Liu F. Apigenin inhibits the self-renewal capacity of human ovarian cancer SKOV3derived sphere-forming cells. Mol Med Rep 2015; 11:2221-2226.
    • (2015) Mol Med Rep , vol.11 , pp. 2221-2226
    • Tang, A.Q.1    Cao, X.C.2    Tian, L.3    He, L.4    Liu, F.5
  • 15
    • 0027614205 scopus 로고
    • Stevioside and related sweet diterpenoid glycosides
    • Hanson JR, De Oliveira BH. Stevioside and related sweet diterpenoid glycosides. Nat Prod Rep 1993; 10: 301-309.
    • (1993) Nat Prod Rep , vol.10 , pp. 301-309
    • Hanson, J.R.1    De Oliveira, B.H.2
  • 16
    • 0347316397 scopus 로고    scopus 로고
    • Antihyperglycemic effects of stevioside in type 2 diabetic subjects
    • Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004; 53: 73-76.
    • (2004) Metabolism , vol.53 , pp. 73-76
    • Gregersen, S.1    Jeppesen, P.B.2    Holst, J.J.3    Hermansen, K.4
  • 17
    • 57749106147 scopus 로고    scopus 로고
    • Stevioside and related compounds: Therapeutic benefits beyond sweetness
    • Chatsudthipong V, Muanprasat C. Stevioside and related compounds: therapeutic benefits beyond sweetness. Pharmacol Ther 2009; 121: 41-54.
    • (2009) Pharmacol Ther , vol.121 , pp. 41-54
    • Chatsudthipong, V.1    Muanprasat, C.2
  • 19
    • 84867790336 scopus 로고    scopus 로고
    • Stevioside induced ROS-mediated apoptosis through mitochondrial pathway in human breast cancer cell line MCF-7
    • Paul S, Sengupta S, Bandyopadhyay TK, Bhattacharyya A. Stevioside induced ROS-mediated apoptosis through mitochondrial pathway in human breast cancer cell line MCF-7. Nutr Cancer 2012; 64:1087-1094.
    • (2012) Nutr Cancer , vol.64 , pp. 1087-1094
    • Paul, S.1    Sengupta, S.2    Bandyopadhyay, T.K.3    Bhattacharyya, A.4
  • 20
    • 0037163259 scopus 로고    scopus 로고
    • Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin
    • Park HR, Furihata K, Hayakawa Y, Shin-ya K. Versipelostatin, a novel GRP78/Bip molecular chaperone down-regulator of microbial origin. Tetrahedron Letters 2002; 43: 6941-6945.
    • (2002) Tetrahedron Letters , vol.43 , pp. 6941-6945
    • Park, H.R.1    Furihata, K.2    Hayakawa, Y.3    Shin-Ya, K.4
  • 21
    • 13444282282 scopus 로고    scopus 로고
    • Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line
    • Chang J, Hsu Y, Kuo P, Kuo Y, Chiang L, Lin C. Increase of Bax/ Bcl-XL ratio and arrest of cell cycle by luteolin in immortalized human hepatoma cell line. Life Sciences 2005; 76: 1883-1893.
    • (2005) Life Sciences , vol.76 , pp. 1883-1893
    • Chang, J.1    Hsu, Y.2    Kuo, P.3    Kuo, Y.4    Chiang, L.5    Lin, C.6
  • 22
    • 27644568638 scopus 로고    scopus 로고
    • Quercetin-induced growth inhibition and cell death in prostatic carcinoma cells (PC-3) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression
    • Vijayababu MR, Kanagaraj P, Arunkumar A, Ilangovan R, Aruldhas MM, Arunakaran J. Quercetin-induced growth inhibition and cell death in prostatic carcinoma cells (PC-3) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression. J Cancer Res Clin Oncol 2005; 131: 765-771.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 765-771
    • Vijayababu, M.R.1    Kanagaraj, P.2    Arunkumar, A.3    Ilangovan, R.4    Aruldhas, M.M.5    Arunakaran, J.6
  • 23
    • 0036644215 scopus 로고    scopus 로고
    • Regulation and measurement of oxidative stress in apoptosis
    • Curtin JF, Donovan M, Cotter TG. Regulation and measurement of oxidative stress in apoptosis. J Immunol Methods 2002; 265: 49-72.
    • (2002) J Immunol Methods , vol.265 , pp. 49-72
    • Curtin, J.F.1    Donovan, M.2    Cotter, T.G.3
  • 25
    • 79961101955 scopus 로고    scopus 로고
    • Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: Implications for PET imaging of human tumors
    • Martinez-Outschoorn UE, Lin Z, Trimmer C, Flomenberg N, Wang C, Pavlides S, Pestell RG, Howell A, Sotgia F, Lisanti MP. Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors. Cell Cycle 2011; 10: 2504-2520.
    • (2011) Cell Cycle , vol.10 , pp. 2504-2520
    • Martinez-Outschoorn, U.E.1    Lin, Z.2    Trimmer, C.3    Flomenberg, N.4    Wang, C.5    Pavlides, S.6    Pestell, R.G.7    Howell, A.8    Sotgia, F.9    Lisanti, M.P.10
  • 26
    • 35348994881 scopus 로고    scopus 로고
    • GADD153 mediates berberine-induced apoptosis in human cervical cancer Ca ski cells
    • Lin JP, Yang JS, Chang NW, Chiu TH, Su CC. GADD153 mediates berberine-induced apoptosis in human cervical cancer Ca ski cells. Anticancer Res 2007; 27: 3379-3386.
    • (2007) Anticancer Res , vol.27 , pp. 3379-3386
    • Lin, J.P.1    Yang, J.S.2    Chang, N.W.3    Chiu, T.H.4    Su, C.C.5
  • 27
    • 0037879052 scopus 로고    scopus 로고
    • The mitochondrial membrane potential (Deltapsi(m)) in apoptosis; an update
    • Ly JD, Grubb DR, Lawen A. The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update. Apoptosis 2003; 8: 115-128.
    • (2003) Apoptosis , vol.8 , pp. 115-128
    • Ly, J.D.1    Grubb, D.R.2    Lawen, A.3
  • 28
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: A hard Akt to follow
    • Brazil DP, Hemmings BA. Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem Sci 2001; 26: 657-664.
    • (2001) Trends Biochem Sci , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 29
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • Nicholson KM, Anderson NG. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal 2002; 14: 381-395.
    • (2002) Cell Signal , vol.14 , pp. 381-395
    • Nicholson, K.M.1    Erson, N.G.2
  • 30
    • 0043053467 scopus 로고    scopus 로고
    • Inhibitory effect of stevioside on tumor promotion by 12-Otetradecanoylphorbol- 13-acetate in two-stage carcinogenesis in mouse skin
    • Yasukawa K, Kitanaka S, Seo S. Inhibitory effect of stevioside on tumor promotion by 12-Otetradecanoylphorbol- 13-acetate in two-stage carcinogenesis in mouse skin. Biol Pharm Bull 2002; 25: 1488-1490.
    • (2002) Biol Pharm Bull , vol.25 , pp. 1488-1490
    • Yasukawa, K.1    Kitanaka, S.2    Seo, S.3
  • 33
    • 70349172938 scopus 로고    scopus 로고
    • Apoptosis and glutathione: Beyond an antioxidant
    • Franco R, Cidlowski JA. Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ 2009; 16: 1303-1314.
    • (2009) Cell Death Differ , vol.16 , pp. 1303-1314
    • Franco, R.1    Cidlowski, J.A.2
  • 34
    • 0036258184 scopus 로고    scopus 로고
    • Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins
    • O'Rourke TW, Doudican NA, Mackereth MD, Doetsch PW, Shadel GS. Mitochondrial dysfunction due to oxidative mitochondrial DNA damage is reduced through cooperative actions of diverse proteins. Mol Cell Biol 2002; 22:4086-4093.
    • (2002) Mol Cell Biol , vol.22 , pp. 4086-4093
    • O'rourke, T.W.1    Doudican, N.A.2    Mackereth, M.D.3    Doetsch, P.W.4    Shadel, G.S.5
  • 35
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 36
    • 33745662190 scopus 로고    scopus 로고
    • Redox biology is a fundamental theme of aerobic life
    • Halliwell B. Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. Plant Physiol 2006; 141: 312-322.
    • (2006) Plant Physiol , vol.141 , pp. 312-322
    • Species, H.B.R.1
  • 37
    • 0642318060 scopus 로고    scopus 로고
    • Changes in mitochondrial membrane potential and mitochondrial mass occur independent of the activation of caspase-8 and caspase-3 during CD95-mediated apoptosis in peripheral blood T cells
    • Gollapudi S, McCormick MJ, Gupta S. Changes in mitochondrial membrane potential and mitochondrial mass occur independent of the activation of caspase-8 and caspase-3 during CD95-mediated apoptosis in peripheral blood T cells. Int J Oncol 2003; 22:597-600.
    • (2003) Int J Oncol , vol.22 , pp. 597-600
    • Gollapudi, S.1    McCormick, M.J.2    Gupta, S.3
  • 38
    • 0036478928 scopus 로고    scopus 로고
    • The Apaf-1 apoptosome: A large caspase-activating complex
    • Cain K, Bratton SB, Cohen GM. The Apaf-1 apoptosome: a large caspase-activating complex. Biochimie 2002; 84:203-214.
    • (2002) Biochimie , vol.84 , pp. 203-214
    • Cain, K.1    Bratton, S.B.2    Cohen, G.M.3
  • 39
    • 0028568315 scopus 로고
    • Cell cycle control and cancer
    • Hartwell LH, Kastan MB. Cell cycle control and cancer. Science 1994; 266: 1821-1828.
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 40
    • 33845973448 scopus 로고    scopus 로고
    • Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells
    • Sun J, Hai Liu R. Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells. Cancer Lett 2006; 241: 124-134.
    • (2006) Cancer Lett , vol.241 , pp. 124-134
    • Sun, J.1    Hai Liu, R.2
  • 41
    • 0032881288 scopus 로고    scopus 로고
    • AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation
    • Chan TO, Rittenhouse SE, Tsichlis PN. AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation. Annu Rev Biochem 1999; 68: 965-1014.
    • (1999) Annu Rev Biochem , vol.68 , pp. 965-1014
    • Chan, T.O.1    Rittenhouse, S.E.2    Tsichlis, P.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.