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Volumn 151, Issue , 2017, Pages S30-S33

Placental hemostasis and sterile inflammation: New insights into gestational vascular disease

Author keywords

Antiplatelet therapy; Gestational vascular disease; Low grade inflammation; Placenta mediated complications; Platelets

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTITHROMBOCYTIC AGENT; CRYOPYRIN; INFLAMMASOME; PURINERGIC RECEPTOR;

EID: 85014154992     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/S0049-3848(17)30063-4     Document Type: Article
Times cited : (23)

References (57)
  • 1
    • 79251491015 scopus 로고    scopus 로고
    • Microparticles and pregnancy complications
    • [1] Aharon, A., Brenner, B., Microparticles and pregnancy complications. Thromb Res 127:Suppl 3 (2011), S67–S71.
    • (2011) Thromb Res , vol.127 , pp. S67-S71
    • Aharon, A.1    Brenner, B.2
  • 2
    • 79952641196 scopus 로고    scopus 로고
    • Inflammation and pregnancy: the role of the immune system at the implantation site
    • [2] Mor, G., et al. Inflammation and pregnancy: the role of the immune system at the implantation site. Ann N Y Acad Sci 1221 (2011), 80–87.
    • (2011) Ann N Y Acad Sci , vol.1221 , pp. 80-87
    • Mor, G.1
  • 3
    • 84865300272 scopus 로고    scopus 로고
    • Biomarkers of coagulation, inflammation, and angiogenesis are independently associated with preeclampsia
    • [3] Boij, R., et al. Biomarkers of coagulation, inflammation, and angiogenesis are independently associated with preeclampsia. Am J Reprod Immunol 68:3 (2012), 258–270.
    • (2012) Am J Reprod Immunol , vol.68 , Issue.3 , pp. 258-270
    • Boij, R.1
  • 4
    • 84873161255 scopus 로고    scopus 로고
    • Pathogenesis of the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP): a review
    • [4] Abildgaard, U., Heimdal, K., Pathogenesis of the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP): a review. Eur J Obstet Gynecol Reprod Biol 166:2 (2013), 117–123.
    • (2013) Eur J Obstet Gynecol Reprod Biol , vol.166 , Issue.2 , pp. 117-123
    • Abildgaard, U.1    Heimdal, K.2
  • 5
    • 40849096217 scopus 로고    scopus 로고
    • Placental origins of preeclampsia: challenging the current hypothesis
    • [5] Huppertz, B., Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 51:4 (2008), 970–975.
    • (2008) Hypertension , vol.51 , Issue.4 , pp. 970-975
    • Huppertz, B.1
  • 6
    • 0027976845 scopus 로고
    • Increased platelet volume and aggregation precede the onset of preeclampsia
    • [6] Hutt, R., et al. Increased platelet volume and aggregation precede the onset of preeclampsia. Obstet Gynecol 83:1 (1994), 146–149.
    • (1994) Obstet Gynecol , vol.83 , Issue.1 , pp. 146-149
    • Hutt, R.1
  • 7
    • 0022383860 scopus 로고
    • Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy-induced hypertension
    • [7] Morrison, R., et al. Platelet behaviour in normal pregnancy, pregnancy complicated by essential hypertension and pregnancy-induced hypertension. Thromb Haemost 54:3 (1985), 607–611.
    • (1985) Thromb Haemost , vol.54 , Issue.3 , pp. 607-611
    • Morrison, R.1
  • 8
    • 0029431572 scopus 로고
    • Biochemical-morphological modifications of platelet membranes during pregnancy-induced hypertension
    • [8] Rabini, R.A., et al. Biochemical-morphological modifications of platelet membranes during pregnancy-induced hypertension. Exp Mol Pathol 63:3 (1995), 175–185.
    • (1995) Exp Mol Pathol , vol.63 , Issue.3 , pp. 175-185
    • Rabini, R.A.1
  • 9
    • 0033499191 scopus 로고    scopus 로고
    • Changes in platelet ATP secretion and aggregation during pregnancy and in preeclampsia
    • [9] Hayashi, M., Kiumi, F., Mitsuya, K., Changes in platelet ATP secretion and aggregation during pregnancy and in preeclampsia. Am J Med Sci 318:2 (1999), 115–121.
    • (1999) Am J Med Sci , vol.318 , Issue.2 , pp. 115-121
    • Hayashi, M.1    Kiumi, F.2    Mitsuya, K.3
  • 10
    • 0030756508 scopus 로고    scopus 로고
    • Defective platelet activation in G alpha(q)-deficient mice
    • [10] Offermanns, S., et al. Defective platelet activation in G alpha(q)-deficient mice. Nature 389:6647 (1997), 183–186.
    • (1997) Nature , vol.389 , Issue.6647 , pp. 183-186
    • Offermanns, S.1
  • 11
    • 2942624713 scopus 로고    scopus 로고
    • Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction
    • [11] Palumbo, J.S., et al. Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction. J Thromb Haemost 2:8 (2004), 1368–1379.
    • (2004) J Thromb Haemost , vol.2 , Issue.8 , pp. 1368-1379
    • Palumbo, J.S.1
  • 12
    • 34249051898 scopus 로고    scopus 로고
    • Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers
    • [12] Sood, R., et al. Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers. J Exp Med 204:5 (2007), 1049–1056.
    • (2007) J Exp Med , vol.204 , Issue.5 , pp. 1049-1056
    • Sood, R.1
  • 13
    • 0035070573 scopus 로고    scopus 로고
    • Tissue-restricted expression of thrombomodulin in the placenta rescues thrombomodulin-deficient mice from early lethality and reveals a secondary developmental block
    • [13] Isermann, B., et al. Tissue-restricted expression of thrombomodulin in the placenta rescues thrombomodulin-deficient mice from early lethality and reveals a secondary developmental block. Development 128:6 (2001), 827–838.
    • (2001) Development , vol.128 , Issue.6 , pp. 827-838
    • Isermann, B.1
  • 14
    • 0037349926 scopus 로고    scopus 로고
    • The thrombomodulin-protein C system is essential for the maintenance of pregnancy
    • [14] Isermann, B., et al. The thrombomodulin-protein C system is essential for the maintenance of pregnancy. Nat Med 9:3 (2003), 331–337.
    • (2003) Nat Med , vol.9 , Issue.3 , pp. 331-337
    • Isermann, B.1
  • 15
    • 27144449028 scopus 로고    scopus 로고
    • Extraembryonic expression of EPCR is essential for embryonic viability
    • [15] Li, W., et al. Extraembryonic expression of EPCR is essential for embryonic viability. Blood 106:8 (2005), 2716–2722.
    • (2005) Blood , vol.106 , Issue.8 , pp. 2716-2722
    • Li, W.1
  • 16
    • 84936891896 scopus 로고    scopus 로고
    • Inflammasomes: mechanism of action, role in disease, and therapeutics
    • [16] Guo, H., Callaway, J.B., Ting, J.P., Inflammasomes: mechanism of action, role in disease, and therapeutics. Nat Med 21:7 (2015), 677–687.
    • (2015) Nat Med , vol.21 , Issue.7 , pp. 677-687
    • Guo, H.1    Callaway, J.B.2    Ting, J.P.3
  • 17
    • 22444433175 scopus 로고    scopus 로고
    • NLRs join TLRs as innate sensors of pathogens
    • [17] Martinon, F., Tschopp, J., NLRs join TLRs as innate sensors of pathogens. Trends Immunol 26:8 (2005), 447–454.
    • (2005) Trends Immunol , vol.26 , Issue.8 , pp. 447-454
    • Martinon, F.1    Tschopp, J.2
  • 18
    • 84865510453 scopus 로고    scopus 로고
    • Biochemical regulation of the inflammasome
    • [18] Dowling, J.K., O'Neill, L.A., Biochemical regulation of the inflammasome. Crit Rev Biochem Mol Biol 47:5 (2012), 424–443.
    • (2012) Crit Rev Biochem Mol Biol , vol.47 , Issue.5 , pp. 424-443
    • Dowling, J.K.1    O'Neill, L.A.2
  • 19
    • 47249089097 scopus 로고    scopus 로고
    • IL-1, IL-18, and IL-33 families of cytokines
    • [19] Arend, W.P., Palmer, G., Gabay, C., IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 223 (2008), 20–38.
    • (2008) Immunol Rev , vol.223 , pp. 20-38
    • Arend, W.P.1    Palmer, G.2    Gabay, C.3
  • 20
    • 84873087532 scopus 로고    scopus 로고
    • NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
    • [20] Heneka, M.T., et al. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature 493:7434 (2013), 674–678.
    • (2013) Nature , vol.493 , Issue.7434 , pp. 674-678
    • Heneka, M.T.1
  • 21
    • 84920134906 scopus 로고    scopus 로고
    • Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy
    • [21] Shahzad, K., et al. Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy. Kidney Int 87:1 (2015), 74–84.
    • (2015) Kidney Int , vol.87 , Issue.1 , pp. 74-84
    • Shahzad, K.1
  • 22
    • 84874524481 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration
    • [22] Tseng, W.A., et al. NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci 54:1 (2013), 110–120.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , Issue.1 , pp. 110-120
    • Tseng, W.A.1
  • 23
    • 85014152809 scopus 로고    scopus 로고
    • Maternal extracellular vesicles and platelets promote preeclampsia through inflammasome activation in embryonic trophoblast
    • [23] Kohli, S., et al. Maternal extracellular vesicles and platelets promote preeclampsia through inflammasome activation in embryonic trophoblast. Blood, 2016.
    • (2016) Blood
    • Kohli, S.1
  • 24
    • 84878810794 scopus 로고    scopus 로고
    • A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1beta production by human first trimester trophoblast
    • [24] Mulla, M.J., et al. A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1beta production by human first trimester trophoblast. PLoS One, 8(6), 2013, e65237.
    • (2013) PLoS One , vol.8 , Issue.6
    • Mulla, M.J.1
  • 25
    • 84878810794 scopus 로고    scopus 로고
    • A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1beta production by human first trimester trophoblast
    • [24] Mulla, M.J., et al. A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1beta production by human first trimester trophoblast. PLoS One, 8(6), 2013, e65237.
    • (2013) PLoS One , vol.8 , Issue.6
    • Mulla, M.J.1
  • 26
    • 84973480978 scopus 로고    scopus 로고
    • Palmitic acid induces interleukin-1beta secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells
    • [25] Shirasuna, K., et al. Palmitic acid induces interleukin-1beta secretion via NLRP3 inflammasomes and inflammatory responses through ROS production in human placental cells. J Reprod Immunol 116 (2016), 104–112.
    • (2016) J Reprod Immunol , vol.116 , pp. 104-112
    • Shirasuna, K.1
  • 27
    • 84929726621 scopus 로고    scopus 로고
    • A clear and present danger: inflammasomes DAMPing down disorders of pregnancy
    • [26] Khan, R.N., Hay, D.P., A clear and present danger: inflammasomes DAMPing down disorders of pregnancy. Hum Reprod Update 21:3 (2015), 388–405.
    • (2015) Hum Reprod Update , vol.21 , Issue.3 , pp. 388-405
    • Khan, R.N.1    Hay, D.P.2
  • 28
    • 84947717560 scopus 로고    scopus 로고
    • Evidence of inflammation and predisposition toward metabolic syndrome after pre-eclampsia
    • [27] Murphy, M.S., Tayade, C., Smith, G.N., Evidence of inflammation and predisposition toward metabolic syndrome after pre-eclampsia. Pregnancy Hypertens 5:4 (2015), 354–358.
    • (2015) Pregnancy Hypertens , vol.5 , Issue.4 , pp. 354-358
    • Murphy, M.S.1    Tayade, C.2    Smith, G.N.3
  • 29
    • 72149130062 scopus 로고    scopus 로고
    • Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia
    • [28] Xie, F., et al. Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia. BJOG 117:1 (2010), 99–108.
    • (2010) BJOG , vol.117 , Issue.1 , pp. 99-108
    • Xie, F.1
  • 30
    • 84924559749 scopus 로고    scopus 로고
    • Inflammasome in platelets: allying coagulation and inflammation in infectious and sterile diseases?
    • [29] Hottz, E.D., et al. Inflammasome in platelets: allying coagulation and inflammation in infectious and sterile diseases?. Mediators Inflamm, 2015, 2015, 435783.
    • (2015) Mediators Inflamm , vol.2015 , pp. 435783
    • Hottz, E.D.1
  • 31
    • 84938826085 scopus 로고    scopus 로고
    • Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study
    • [30] Zaborowski, M.P., et al. Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study. Bioscience 65:8 (2015), 783–797.
    • (2015) Bioscience , vol.65 , Issue.8 , pp. 783-797
    • Zaborowski, M.P.1
  • 32
    • 84923876658 scopus 로고    scopus 로고
    • Placental extracellular vesicles and feto-maternal communication
    • [31] Tong, M., Chamley, L.W., Placental extracellular vesicles and feto-maternal communication. Cold Spring Harb Perspect Med, 5(3), 2015, a023028.
    • (2015) Cold Spring Harb Perspect Med , vol.5 , Issue.3 , pp. a023028
    • Tong, M.1    Chamley, L.W.2
  • 33
    • 84942615121 scopus 로고    scopus 로고
    • Placental exosomes in normal and complicated pregnancy
    • [32] Mitchell, M.D., et al. Placental exosomes in normal and complicated pregnancy. Am J Obstet Gynecol 213:4 Suppl (2015), S173–S181.
    • (2015) Am J Obstet Gynecol , vol.213 , Issue.4 , pp. S173-S181
    • Mitchell, M.D.1
  • 34
    • 84923012325 scopus 로고    scopus 로고
    • The role of extracellular vesicles in placental vascular complications
    • [33] Aharon, A., The role of extracellular vesicles in placental vascular complications. Thromb Res 135:Suppl 1 (2015), S23–S25.
    • (2015) Thromb Res , vol.135 , pp. S23-S25
    • Aharon, A.1
  • 35
    • 35048852484 scopus 로고    scopus 로고
    • Microparticles from apoptotic monocytes induce transient platelet recruitment and tissue factor expression by cultured human vascular endothelial cells via a redox-sensitive mechanism
    • [34] Essayagh, S., et al. Microparticles from apoptotic monocytes induce transient platelet recruitment and tissue factor expression by cultured human vascular endothelial cells via a redox-sensitive mechanism. Thromb Haemost 98:4 (2007), 831–837.
    • (2007) Thromb Haemost , vol.98 , Issue.4 , pp. 831-837
    • Essayagh, S.1
  • 36
    • 84886417281 scopus 로고    scopus 로고
    • Microvesicles of women with gestational hypertension and preeclampsia affect human trophoblast fate and endothelial function
    • [35] Shomer, E., et al. Microvesicles of women with gestational hypertension and preeclampsia affect human trophoblast fate and endothelial function. Hypertension 62:5 (2013), 893–898.
    • (2013) Hypertension , vol.62 , Issue.5 , pp. 893-898
    • Shomer, E.1
  • 37
    • 65849366758 scopus 로고    scopus 로고
    • Microparticles bearing tissue factor and tissue factor pathway inhibitor in gestational vascular complications
    • [36] Aharon, A., et al. Microparticles bearing tissue factor and tissue factor pathway inhibitor in gestational vascular complications. J Thromb Haemost 7:6 (2009), 1047–1050.
    • (2009) J Thromb Haemost , vol.7 , Issue.6 , pp. 1047-1050
    • Aharon, A.1
  • 38
    • 0035173279 scopus 로고    scopus 로고
    • Circulating procoagulant microparticles in women with unexplained pregnancy loss: a new insight
    • [37] Laude, I., et al. Circulating procoagulant microparticles in women with unexplained pregnancy loss: a new insight. Thromb Haemost 85:1 (2001), 18–21.
    • (2001) Thromb Haemost , vol.85 , Issue.1 , pp. 18-21
    • Laude, I.1
  • 39
    • 0037342076 scopus 로고    scopus 로고
    • Circulating microparticles: a marker of procoagulant state in normal pregnancy and pregnancy complicated by preeclampsia or intrauterine growth restriction
    • [38] Bretelle, F., et al. Circulating microparticles: a marker of procoagulant state in normal pregnancy and pregnancy complicated by preeclampsia or intrauterine growth restriction. Thromb Haemost 89:3 (2003), 486–492.
    • (2003) Thromb Haemost , vol.89 , Issue.3 , pp. 486-492
    • Bretelle, F.1
  • 40
    • 0036914683 scopus 로고    scopus 로고
    • Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries from healthy pregnant women
    • [39] Vanwijk, M.J., et al. Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries from healthy pregnant women. Am J Obstet Gynecol 187:6 (2002), 1686–1693.
    • (2002) Am J Obstet Gynecol , vol.187 , Issue.6 , pp. 1686-1693
    • Vanwijk, M.J.1
  • 41
    • 84867628025 scopus 로고    scopus 로고
    • Circulating microparticles in severe preeclampsia
    • [40] Marques, F.K., et al. Circulating microparticles in severe preeclampsia. Clin Chim Acta 414 (2012), 253–258.
    • (2012) Clin Chim Acta , vol.414 , pp. 253-258
    • Marques, F.K.1
  • 42
    • 84952684542 scopus 로고    scopus 로고
    • Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function
    • [41] Tannetta, D.S., et al. Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function. PLoS One, 10(11), 2015, e0142538.
    • (2015) PLoS One , vol.10 , Issue.11
    • Tannetta, D.S.1
  • 43
    • 0031802535 scopus 로고    scopus 로고
    • Circulating factors as markers and mediators of endothelial cell dysfunction in preeclampsia
    • [42] Taylor, R.N., et al. Circulating factors as markers and mediators of endothelial cell dysfunction in preeclampsia. Semin Reprod Endocrinol 16:1 (1998), 17–31.
    • (1998) Semin Reprod Endocrinol , vol.16 , Issue.1 , pp. 17-31
    • Taylor, R.N.1
  • 44
    • 2642525995 scopus 로고    scopus 로고
    • Platelet activation in the hypertensive disorders of pregnancy
    • [43] Nadar, S., Lip, G.Y., Platelet activation in the hypertensive disorders of pregnancy. Expert Opin Investig Drugs 13:5 (2004), 523–529.
    • (2004) Expert Opin Investig Drugs , vol.13 , Issue.5 , pp. 523-529
    • Nadar, S.1    Lip, G.Y.2
  • 45
    • 84929319009 scopus 로고    scopus 로고
    • Platelet secretion: From haemostasis to wound healing and beyond
    • [44] Golebiewska, E.M., Poole, A.W., Platelet secretion: From haemostasis to wound healing and beyond. Blood Rev 29:3 (2015), 153–162.
    • (2015) Blood Rev , vol.29 , Issue.3 , pp. 153-162
    • Golebiewska, E.M.1    Poole, A.W.2
  • 46
    • 84902239356 scopus 로고    scopus 로고
    • Danger signals from ATP and adenosine in pregnancy and preeclampsia
    • [45] Spaans, F., et al. Danger signals from ATP and adenosine in pregnancy and preeclampsia. Hypertension 63:6 (2014), 1154–1160.
    • (2014) Hypertension , vol.63 , Issue.6 , pp. 1154-1160
    • Spaans, F.1
  • 47
    • 6344283049 scopus 로고    scopus 로고
    • Targeted disruption of cd73/ecto-5’-nucleotidase alters thromboregulation and augments vascular inflammatory response
    • [46] Koszalka, P., et al. Targeted disruption of cd73/ecto-5’-nucleotidase alters thromboregulation and augments vascular inflammatory response. Circ Res 95:8 (2004), 814–821.
    • (2004) Circ Res , vol.95 , Issue.8 , pp. 814-821
    • Koszalka, P.1
  • 48
    • 77954792277 scopus 로고    scopus 로고
    • Extracellular ATP induces albuminuria in pregnant rats
    • [47] Faas, M.M., et al. Extracellular ATP induces albuminuria in pregnant rats. Nephrol Dial Transplant 25:8 (2010), 2468–2478.
    • (2010) Nephrol Dial Transplant , vol.25 , Issue.8 , pp. 2468-2478
    • Faas, M.M.1
  • 49
    • 84876466231 scopus 로고    scopus 로고
    • Overexpression of CD39 protects in a mouse model of preeclampsia
    • [48] McRae, J.L., et al. Overexpression of CD39 protects in a mouse model of preeclampsia. Nephrology (Carlton) 18:5 (2013), 351–355.
    • (2013) Nephrology (Carlton) , vol.18 , Issue.5 , pp. 351-355
    • McRae, J.L.1
  • 50
    • 84922271813 scopus 로고    scopus 로고
    • Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy: executive summary
    • [49] Magee, L.A., et al. Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy: executive summary. J Obstet Gynaecol Can 36:7 (2014), 575–576.
    • (2014) J Obstet Gynaecol Can , vol.36 , Issue.7 , pp. 575-576
    • Magee, L.A.1
  • 51
    • 0030733012 scopus 로고    scopus 로고
    • Hazards of heparin: allergy, heparin-induced thrombocytopenia and osteoporosis
    • [50] Nelson-Piercy, C., Hazards of heparin: allergy, heparin-induced thrombocytopenia and osteoporosis. Baillieres Clin Obstet Gynaecol 11:3 (1997), 489–509.
    • (1997) Baillieres Clin Obstet Gynaecol , vol.11 , Issue.3 , pp. 489-509
    • Nelson-Piercy, C.1
  • 52
    • 0024523847 scopus 로고
    • Low molecular weight heparin Novo (LHN-1) does not cross the placenta during the second trimester of pregnancy
    • [51] Omri, A., et al. Low molecular weight heparin Novo (LHN-1) does not cross the placenta during the second trimester of pregnancy. Thromb Haemost 61:1 (1989), 55–56.
    • (1989) Thromb Haemost , vol.61 , Issue.1 , pp. 55-56
    • Omri, A.1
  • 53
    • 34249034723 scopus 로고    scopus 로고
    • Antiplatelet agents for preventing pre-eclampsia and its complications
    • [52] Duley, L., et al. Antiplatelet agents for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev, 2, 2007, CD004659.
    • (2007) Cochrane Database Syst Rev , vol.2
    • Duley, L.1
  • 54
    • 0035835423 scopus 로고    scopus 로고
    • Antiplatelet drugs for prevention of pre-eclampsia and its consequences: systematic review
    • [53] Duley, L., et al. Antiplatelet drugs for prevention of pre-eclampsia and its consequences: systematic review. BMJ 322:7282 (2001), 329–333.
    • (2001) BMJ , vol.322 , Issue.7282 , pp. 329-333
    • Duley, L.1
  • 55
    • 70350548538 scopus 로고    scopus 로고
    • Platelet antiaggregants in pregnancy
    • [54] Santiago-Diaz, P., et al. Platelet antiaggregants in pregnancy. Rev Esp Cardiol 62:10 (2009), 1197–1198.
    • (2009) Rev Esp Cardiol , vol.62 , Issue.10 , pp. 1197-1198
    • Santiago-Diaz, P.1
  • 56
    • 84860395312 scopus 로고    scopus 로고
    • Clopidogrel treatment during pregnancy: a case report and a review of literature
    • [55] De Santis, M., et al. Clopidogrel treatment during pregnancy: a case report and a review of literature. Intern Med 50:16 (2011), 1769–1773.
    • (2011) Intern Med , vol.50 , Issue.16 , pp. 1769-1773
    • De Santis, M.1
  • 57
    • 84907277765 scopus 로고    scopus 로고
    • Platelet function and long-term antiplatelet therapy in women: is there a gender-specificity? A “state-of-the-art” paper
    • [56] Patti, G., et al. Platelet function and long-term antiplatelet therapy in women: is there a gender-specificity? A “state-of-the-art” paper. Eur Heart J 35:33 (2014), 2213–2223b.
    • (2014) Eur Heart J , vol.35 , Issue.33 , pp. 2213-2223b
    • Patti, G.1


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