메뉴 건너뛰기




Volumn 9, Issue 4, 2017, Pages 462-481

Gene signature driving invasive mucinous adenocarcinoma of the lung

Author keywords

FOXA3; IMA; MUC5AC 5B; SPDEF; VTCN1

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3GAMMA; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; K RAS PROTEIN; MUCIN; MUCIN 3; MUCIN 5AC; MUCIN 5B; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1;

EID: 85014133712     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201606711     Document Type: Article
Times cited : (82)

References (65)
  • 4
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Cancer Genome Atlas Research Network (2014) Comprehensive molecular profiling of lung adenocarcinoma. Nature 511: 543–550
    • (2014) Nature , vol.511 , pp. 543-550
  • 6
    • 70349664159 scopus 로고    scopus 로고
    • SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production
    • Chen G, Korfhagen TR, Xu Y, Kitzmiller J, Wert SE, Maeda Y, Gregorieff A, Clevers H, Whitsett JA (2009) SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production. J Clin Invest 119: 2914–2924
    • (2009) J Clin Invest , vol.119 , pp. 2914-2924
    • Chen, G.1    Korfhagen, T.R.2    Xu, Y.3    Kitzmiller, J.4    Wert, S.E.5    Maeda, Y.6    Gregorieff, A.7    Clevers, H.8    Whitsett, J.A.9
  • 9
    • 80053219464 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling
    • Choi YH, Lee SN, Aoyagi H, Yamasaki Y, Yoo JY, Park B, Shin DM, Yoon HG, Yoon JH (2011) The extracellular signal-regulated kinase mitogen-activated protein kinase/ribosomal S6 protein kinase 1 cascade phosphorylates cAMP response element-binding protein to induce MUC5B gene expression via D-prostanoid receptor signaling. J Biol Chem 286: 34199–34214
    • (2011) J Biol Chem , vol.286 , pp. 34199-34214
    • Choi, Y.H.1    Lee, S.N.2    Aoyagi, H.3    Yamasaki, Y.4    Yoo, J.Y.5    Park, B.6    Shin, D.M.7    Yoon, H.G.8    Yoon, J.H.9
  • 11
    • 0042635811 scopus 로고    scopus 로고
    • Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression
    • Feldman RJ, Sementchenko VI, Gayed M, Fraig MM, Watson DK (2003) Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression. Cancer Res 63: 4626–4631
    • (2003) Cancer Res , vol.63 , pp. 4626-4631
    • Feldman, R.J.1    Sementchenko, V.I.2    Gayed, M.3    Fraig, M.M.4    Watson, D.K.5
  • 17
    • 0034802736 scopus 로고    scopus 로고
    • Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen
    • Ghadersohi A, Sood AK (2001) Prostate epithelium-derived Ets transcription factor mRNA is overexpressed in human breast tumors and is a candidate breast tumor marker and a breast tumor antigen. Clin Cancer Res 7: 2731–2738
    • (2001) Clin Cancer Res , vol.7 , pp. 2731-2738
    • Ghadersohi, A.1    Sood, A.K.2
  • 18
    • 49749143436 scopus 로고    scopus 로고
    • Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients
    • Ghadersohi A, Odunsi K, Zhang S, Azrak RG, Bundy BN, Manjili MH, Li F (2008) Prostate-derived Ets transcription factor as a favorable prognostic marker in ovarian cancer patients. Int J Cancer 123: 1376–1384
    • (2008) Int J Cancer , vol.123 , pp. 1376-1384
    • Ghadersohi, A.1    Odunsi, K.2    Zhang, S.3    Azrak, R.G.4    Bundy, B.N.5    Manjili, M.H.6    Li, F.7
  • 19
    • 84858206832 scopus 로고    scopus 로고
    • Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy
    • Green MR, Rodig S, Juszczynski P, Ouyang J, Sinha P, O'Donnell E, Neuberg D, Shipp MA (2012) Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy. Clin Cancer Res 18: 1611–1618
    • (2012) Clin Cancer Res , vol.18 , pp. 1611-1618
    • Green, M.R.1    Rodig, S.2    Juszczynski, P.3    Ouyang, J.4    Sinha, P.5    O'Donnell, E.6    Neuberg, D.7    Shipp, M.A.8
  • 22
    • 77955107907 scopus 로고    scopus 로고
    • Frequency of EGFR and KRAS mutations in Japanese patients with lung adenocarcinoma with features of the mucinous subtype of bronchioloalveolar carcinoma
    • Hata A, Katakami N, Fujita S, Kaji R, Imai Y, Takahashi Y, Nishimura T, Tomii K, Ishihara K (2010) Frequency of EGFR and KRAS mutations in Japanese patients with lung adenocarcinoma with features of the mucinous subtype of bronchioloalveolar carcinoma. J Thorac Oncol 5: 1197–1200
    • (2010) J Thorac Oncol , vol.5 , pp. 1197-1200
    • Hata, A.1    Katakami, N.2    Fujita, S.3    Kaji, R.4    Imai, Y.5    Takahashi, Y.6    Nishimura, T.7    Tomii, K.8    Ishihara, K.9
  • 24
    • 84989201871 scopus 로고    scopus 로고
    • New and emerging targeted treatments in advanced non-small-cell lung cancer
    • Hirsch FR, Suda K, Wiens J, Bunn PA Jr (2016) New and emerging targeted treatments in advanced non-small-cell lung cancer. Lancet 388: 1012–1024
    • (2016) Lancet , vol.388 , pp. 1012-1024
    • Hirsch, F.R.1    Suda, K.2    Wiens, J.3    Bunn, P.A.4
  • 25
    • 84925481847 scopus 로고    scopus 로고
    • Cancer cell-associated cytoplasmic B7-H4 is induced by hypoxia through hypoxia-inducible factor-1α and promotes cancer cell proliferation
    • Jeon YK, Park SG, Choi IW, Lee SW, Lee SM, Choi I (2015) Cancer cell-associated cytoplasmic B7-H4 is induced by hypoxia through hypoxia-inducible factor-1α and promotes cancer cell proliferation. Biochem Biophys Res Commun 459: 277–283
    • (2015) Biochem Biophys Res Commun , vol.459 , pp. 277-283
    • Jeon, Y.K.1    Park, S.G.2    Choi, I.W.3    Lee, S.W.4    Lee, S.M.5    Choi, I.6
  • 29
    • 70450247207 scopus 로고    scopus 로고
    • Mucins in cancer: function, prognosis and therapy
    • Kufe DW (2009) Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer 9: 874–885
    • (2009) Nat Rev Cancer , vol.9 , pp. 874-885
    • Kufe, D.W.1
  • 30
  • 31
    • 31444451661 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274)
    • Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, Park YM, Oh S, Shin JG, Yao S, Chen L et al (2006) Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274). FEBS Lett 580: 755–762
    • (2006) FEBS Lett , vol.580 , pp. 755-762
    • Lee, S.J.1    Jang, B.C.2    Lee, S.W.3    Yang, Y.I.4    Suh, S.I.5    Park, Y.M.6    Oh, S.7    Shin, J.G.8    Yao, S.9    Chen, L.10
  • 34
    • 79961123152 scopus 로고    scopus 로고
    • RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
    • Li B, Dewey CN (2011) RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12: 323
    • (2011) BMC Bioinformatics , vol.12 , pp. 323
    • Li, B.1    Dewey, C.N.2
  • 36
    • 0038302927 scopus 로고    scopus 로고
    • PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
    • Loke P, Allison JP (2003) PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells. Proc Natl Acad Sci USA 100: 5336–5341
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5336-5341
    • Loke, P.1    Allison, J.P.2
  • 37
    • 84924629414 scopus 로고    scopus 로고
    • Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
    • Love MI, Huber W, Anders S (2014) Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 15: 550
    • (2014) Genome Biol , vol.15 , pp. 550
    • Love, M.I.1    Huber, W.2    Anders, S.3
  • 46
    • 58149340663 scopus 로고    scopus 로고
    • Conditional expression of genes in the respiratory epithelium in transgenic mice: cautionary notes and toward building a better mouse trap
    • Perl AK, Zhang L, Whitsett JA (2009) Conditional expression of genes in the respiratory epithelium in transgenic mice: cautionary notes and toward building a better mouse trap. Am J Respir Cell Mol Biol 40: 1–3
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 1-3
    • Perl, A.K.1    Zhang, L.2    Whitsett, J.A.3
  • 50
    • 70349871718 scopus 로고    scopus 로고
    • CEAS: cis-regulatory element annotation system
    • Shin H, Liu T, Manrai AK, Liu XS (2009) CEAS: cis-regulatory element annotation system. Bioinformatics 25: 2605–2606
    • (2009) Bioinformatics , vol.25 , pp. 2605-2606
    • Shin, H.1    Liu, T.2    Manrai, A.K.3    Liu, X.S.4
  • 51
    • 84938794719 scopus 로고    scopus 로고
    • Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities
    • Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Canales JR et al (2015) Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities. Cancer Discov 5: 860–877
    • (2015) Cancer Discov , vol.5 , pp. 860-877
    • Skoulidis, F.1    Byers, L.A.2    Diao, L.3    Papadimitrakopoulou, V.A.4    Tong, P.5    Izzo, J.6    Behrens, C.7    Kadara, H.8    Parra, E.R.9    Canales, J.R.10
  • 52
    • 84959133719 scopus 로고    scopus 로고
    • Combination cancer immunotherapies tailored to the tumour microenvironment
    • Smyth MJ, Ngiow SF, Ribas A, Teng MW (2016) Combination cancer immunotherapies tailored to the tumour microenvironment. Nat Rev Clin Oncol 13: 143–158
    • (2016) Nat Rev Clin Oncol , vol.13 , pp. 143-158
    • Smyth, M.J.1    Ngiow, S.F.2    Ribas, A.3    Teng, M.W.4
  • 59
    • 84864425198 scopus 로고    scopus 로고
    • A complete workflow for the analysis of full-size ChIP-seq (and similar) data sets using peak-motifs
    • Thomas-Chollier M, Darbo E, Herrmann C, Defrance M, Thieffry D, van Helden J (2012b) A complete workflow for the analysis of full-size ChIP-seq (and similar) data sets using peak-motifs. Nat Protoc 7: 1551–1568
    • (2012) Nat Protoc , vol.7 , pp. 1551-1568
    • Thomas-Chollier, M.1    Darbo, E.2    Herrmann, C.3    Defrance, M.4    Thieffry, D.5    van Helden, J.6
  • 61
    • 79551563284 scopus 로고    scopus 로고
    • International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma
    • Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE et al (2011) International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 6: 244–285
    • (2011) J Thorac Oncol , vol.6 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3    Nicholson, A.G.4    Geisinger, K.R.5    Yatabe, Y.6    Beer, D.G.7    Powell, C.A.8    Riely, G.J.9    Van Schil, P.E.10
  • 62
    • 55549124562 scopus 로고    scopus 로고
    • Global gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progression
    • Turner DP, Findlay VJ, Kirven AD, Moussa O, Watson DK (2008) Global gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progression. Mol Biol Cell 19: 3745–3757
    • (2008) Mol Biol Cell , vol.19 , pp. 3745-3757
    • Turner, D.P.1    Findlay, V.J.2    Kirven, A.D.3    Moussa, O.4    Watson, D.K.5
  • 63
    • 84866995203 scopus 로고    scopus 로고
    • MUC5B leads to aggressive behavior of breast cancer MCF7 cells
    • Valque H, Gouyer V, Gottrand F, Desseyn JL (2012) MUC5B leads to aggressive behavior of breast cancer MCF7 cells. PLoS One 7: e46699
    • (2012) PLoS One , vol.7
    • Valque, H.1    Gouyer, V.2    Gottrand, F.3    Desseyn, J.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.