SPDEF Inhibits Prostate Carcinogenesis by Disrupting a Positive Feedback Loop in Regulation of the Foxm1 Oncogene

PLoS Genetics

Volumn 10, Issue 9, 2014, Pages

  Cheng, Xin Hua ^a   Black, Markaisa ^a   Ustiyan, Vladimir ^a   Le, Tien ^a   Fulford, Logan ^a   Sridharan, Anusha ^a   Medvedovic, Mario ^b   Kalinichenko, Vladimir V ^a   Whitsett, Jeffrey A ^a   Kalin, Tanya V ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; CYCLIN A2; CYCLIN B1; POLO LIKE KINASE 1; PROTEIN TYROSINE PHOSPHATASE; SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, HUMAN; SPDEF PROTEIN, HUMAN; TRANSCRIPTION FACTOR ETS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AURORAB GENE; CANCER GROWTH; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENESIS; CDC25B GENE; CELL PROLIFERATION; CONTROLLED STUDY; CSK1 GENE; CYCLIN A2 GENE; CYCLIN B1 GENE; FOXM1 GENE; GAIN OF FUNCTION MUTATION; GENE; GENE CONTROL; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE INTERACTION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NONHUMAN; ONCOGENE; PLK 1 GENE; POSITIVE FEEDBACK; PROMOTER REGION; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROSTATE CARCINOGENESIS; SPDEF GENE; TOPO2ALPHA GENE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; ANIMAL; CELL TRANSFORMATION; DISEASE MODEL; GENE ORDER; GENE TARGETING; GENETICS; KNOCKOUT MOUSE; METABOLISM; MORTALITY; PATHOLOGY; PROGNOSIS; PROSTATE; PROSTATE TUMOR; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE ORDER; GENE TARGETING; HUMANS; MALE; MICE; MICE, KNOCKOUT; PROGNOSIS; PROSTATE; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-ETS;

EID: 84907572521     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004656     Document Type: Article

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