Cytoprotective role of haptoglobin in brain after experimental intracerebral hemorrhage

Acta Neurochirurgica, Supplementum

Volumn , Issue 111, 2011, Pages 107-112

  Zhao, Xiurong ^a   Song, Shen ^a   Sun, Guanghua ^a   Zhang, Jie ^a   Strong, Roger ^a   Zhang, Lihua ^a   Grotta, James C ^a   Aronowski, Jaroslaw ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Haptoglobin; Hematoma and neuroprotection; Hemoglobin; Intracerebral hemorrhage; Oligodendrocyte

Indexed keywords

HAPTOGLOBIN; HEMOGLOBIN; MESSENGER RNA; LACTATE DEHYDROGENASE; MYELIN BASIC PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN LEVEL; CELL PROTECTION; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE SEVERITY; HEMATOMA; HEMOLYSIS; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; OLIGODENDROGLIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; UPREGULATION; ANIMAL; ANIMAL EMBRYO; ARTICLE; CELL CULTURE; DISEASE MODEL; GENE EXPRESSION REGULATION; GLIA; METABOLISM; MOUSE MUTANT; NERVE CELL; NEUROLOGIC EXAMINATION; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN INJURIES; CELLS, CULTURED; CEREBRAL HEMORRHAGE; CYTOPROTECTION; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; HAPTOGLOBINS; L-LACTATE DEHYDROGENASE; MICE; MICE, KNOCKOUT; MYELIN BASIC PROTEINS; NEUROGLIA; NEUROLOGIC EXAMINATION; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79960663998     PISSN: 00651419     EISSN: 00016268     Source Type: Book Series    
DOI: 10.1007/978-3-7091-0693-8_17     Document Type: Conference Paper

References (29)

1. Wada T et al (1970) Autoradiographic study on the site of uptake of the haptoglobin-hemoglobin complex. J Reticuloendothel Soc 8(2):185-193
2. Zuwala-Jagiello J (2006) Haemoglobin scavenger receptor: func¬tion in relation to disease. Acta Biochim Pol 53(2):257-268 (Pubitemid 44033923)
3. Yang F et al (2003) Haptoglobin reduces lung injury associated with exposure to blood. Am J Physiol Lung Cell Mol Physiol 284(2):L402-L409 (Pubitemid 36164376)
4. Hoj L et al (1984) Secretion rates of immunoglobulins, albumin, haptoglobin and complement factors C3 and C4 in the perfused jejunum and ileum of human Salmonella carriers. Acta Pathol Microbiol Immunol Scand C 92(2):129-132 (Pubitemid 14136787)
5. Bowman BH, Kurosky A (1982) Haptoglobin: the evolutionary product of duplication, unequal crossing over, and point mutation. Adv Hum Genet 12:189, 453-454
6. Schaer DJ et al (2006) CD163 is the macrophage scavenger recep¬tor for native and chemically modifed hemoglobins in the absence of haptoglobin. Blood 107(1):373-380 (Pubitemid 43053566)
7. Philippidis P et al (2004) Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinfammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery. Circ Res 94(1):119-126 (Pubitemid 38064106)
8. Ascenzi P et al (2005) Hemoglobin and heme scavenging. IUBMB Life 57(11):749-759 (Pubitemid 41781830)
9. Schaer DJ et al (2005) Soluble hemoglobin-haptoglobin scavenger receptor CD163 as a lineage-specifc marker in the reactive hemophagocytic syndrome. Eur J Haematol 74(1):6-10 (Pubitemid 40143680)
10. Schaer DJ, Alayash AI, Buehler PW (2007) Gating the radical hemoglobin to macrophages: the anti-infammatory role of CD163, a scavenger receptor. Antioxid Redox Signal 9(7):991-999 (Pubitemid 46919600)
11. D'Armiento J, Dalal SS, Chada K (1997) Tissue, temporal and induc-ible expression pattern of haptoglobin in mice. Gene 195(1):19-27 (Pubitemid 27336956)
12. Chen W et al (1998) Expression of the protective proteins hemopexin and haptoglobin by cells of the neural retina. Exp Eye Res 67(1): 83-93 (Pubitemid 28364817)
13. Borsody M et al (2006) Haptoglobin and the development of cere¬bral artery vasospasm after subarachnoid hemorrhage. Neurology 66(5):634-640 (Pubitemid 43739814)
14. Bhasin RR et al (2002) Experimental intracerebral hemorrhage: effect of lysed erythrocytes on brain edema and blood-brain barrier permeability. Acta Neurochir Suppl 81:249-251
15. Xi G, Keep RF, Hoff JT (1998) Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in rats. J Neurosurg 89(6):991-996 (Pubitemid 28544054)
16. Nakamura T et al (2006) Iron-induced oxidative brain injury after experimental intracerebral hemorrhage. Acta Neurochir Suppl 96:194-198
17. Nakamura T et al (2005) Oxidative DNA injury after experimental intracerebral hemorrhage. Brain Res 1039(1-2):30-36 (Pubitemid 40386824)
18. Regan RF, Panter SS (1993) Neurotoxicity of hemoglobin in corti¬cal cell culture. Neurosci Lett 153(2):219-222 (Pubitemid 23147074)
19. Wang X et al (2002) Hemoglobin-induced cytotoxicity in rat cere¬bral cortical neurons: caspase activation and oxidative stress. Stroke 33(7):1882-1888 (Pubitemid 34761080)
20. Keep RF et al (2008) Blood-brain barrier function in intracerebral hemorrhage. Acta Neurochir Suppl 105:73-77
21. Aronowski J, Hall CE (2005) New horizons for primary intracere-bral hemorrhage treatment: experience from preclinical studies. Neurol Res 27(3):268-279 (Pubitemid 40523798)
22. Xi G, Keep RF, Hoff JT (2006) Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol 5(1):53-63 (Pubitemid 41790696)
23. Koeppen AH, Dickson AC, McEvoy JA (1995) The cellular reac¬tions to experimental intracerebral hemorrhage. J Neurol Sci 134(Suppl):102-112
24. Zhao X et al (2009) Neuroprotective role of haptoglobin after intracerebral hemorrhage. J Neurosci 29(50):15819-15827
25. Lim SK et al (1998) Increased susceptibility in Hp knockout mice during acute hemolysis. Blood 92(6):1870-1877 (Pubitemid 28446675)
26. Yang F et al (1993) Characterization of the mouse haptoglobin gene. Genomics 18(2):374-380 (Pubitemid 23339549)
27. Zhao X et al (2007) Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke 38(12):3280-3286 (Pubitemid 350175749)
28. Wagner KR, Dwyer BE (2004) Hematoma removal, heme, and heme oxygenase following hemorrhagic stroke. Ann NY Acad Sci 1012:237-251 (Pubitemid 38453529)
29. Wagner KR et al (2003) Heme and iron metabolism: role in cerebral hemorrhage. J Cereb Blood Flow Metab 23(6):629-652 (Pubitemid 36713668)