Hemin induces an iron-dependent, oxidative injury to human neuron-like cells

Journal of Neuroscience Research

Volumn 73, Issue 1, 2003, Pages 113-121

  Goldstein, Laurel ^a   Teng, Zhi Peng ^a   Zeserson, Eli ^a   Patel, Monica ^a   Regan, Raymond F ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

CNS hemorrhage; Free radical; Hemoglobin toxicity; Neuron

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE INHIBITOR; DEFEROXAMINE; GLUTATHIONE; HEME OXYGENASE 1; HEME OXYGENASE 2; HEMIN; HEMOGLOBIN; IRON; IRON CHELATE; MERCAPTOETHANOL; PHENANTHROLINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN HEMATOMA; BRAIN HEMORRHAGE; CELL NUCLEUS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXICITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPOTHESIS; NERVE CELL; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROTOXICITY; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELL DIFFERENTIATION; CEREBRAL HEMORRHAGE; FREE RADICALS; HEME OXYGENASE (DECYCLIZING); HEMIN; HUMANS; IRON; IRON CHELATING AGENTS; NEURONS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SULFHYDRYL REAGENTS; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0037716283     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10633     Document Type: Article

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