Necrostatin-1 Ameliorates Intracerebral Hemorrhage-Induced Brain Injury in Mice Through Inhibiting RIP1/RIP3 Pathway

Neurochemical Research

Volumn 40, Issue 4, 2015, Pages 643-650

  Su, Xingfen ^a,b   Wang, Handong ^a   Kang, Dezhi ^b   Zhu, Jianhong ^a   Sun, Qing ^a   Li, Tao ^a   Ding, Ke ^a  

^a NANJING UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Intracerebral hemorrhage; Necroptosis; Necrostatin 1; RIP1; RIP3

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; INTERLEUKIN 1BETA; NECROSTATIN 1; NEUROPROTECTIVE AGENT; PHOSPHOTRANSFERASE INHIBITOR; PROPIDIUM IODIDE; RECEPTOR INTERACTING PROTEIN KINASE 1; RECEPTOR INTERACTING PROTEIN KINASE 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; IMIDAZOLE DERIVATIVE; INDOLE DERIVATIVE; NECROSTATIN-1; RALBP1 PROTEIN, MOUSE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN EDEMA; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN WATER; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; MALE; MICROGLIA; MOTOR PERFORMANCE; MOUSE; NECROPTOSIS; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; BRAIN INJURIES; CEREBRAL HEMORRHAGE; COMPLICATION; DRUG EFFECTS; GENE EXPRESSION; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; NECROSIS; PATHOLOGY;

MUS;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN EDEMA; BRAIN INJURIES; CEREBRAL HEMORRHAGE; CYTOKINES; GENE EXPRESSION; GTPASE-ACTIVATING PROTEINS; IMIDAZOLES; INDOLES; MALE; MICE; MICE, INBRED ICR; MICROGLIA; NECROSIS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES;

EID: 84925870052     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1510-0     Document Type: Article

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