Quantitative analysis of injured, necrotic, and apoptotic cells in a new experimental model of intracerebral hemorrhage

Critical Care Medicine

Volumn 29, Issue 1, 2001, Pages 152-157

  Qureshi, Adnan I ^a,c   Ling, Geoffrey S F ^b   Khan, Jehanzeb ^a   Suri, M Fareed K ^a   Miskolczi, Laszlo ^a   Guterman, Lee R ^a   Hopkins, L Nelson ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c MILLARD FILLMORE HOSPITAL   (United States)

Author keywords

Animal model; Apoptosis; Cytotoxic edema; Histology; Intracerebral hemorrhage; Necrosis

Indexed keywords

EOSIN; HEMATOXYLIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN HEMATOMA; BRAIN HEMORRHAGE; CELL DAMAGE; CELL DEATH; CELL SWELLING; CONTROLLED STUDY; FRONTAL LOBE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RABBIT; WHITE MATTER;

EID: 0035146642     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200101000-00030     Document Type: Article

References (40)

1. Volume of intracerebral hemorrhage: A powerful and easy to use predictor of 30 day mortality
2. Predictors of early deterioration and mortality in black Americans with spontaneous intracerebral hemorrhage
3. Massive cerebral hemorrhages. Clinical and pathological correlations
4. No evidence for an ischemic penumbra in massive experimental intracerebral hemorrhage
5. Apoptosis: Clinical relevance and pharmacological manipulation
6. Apoptosis, excitotoxicity, and neuropathology
7. Experimental intracerebral hemorrhage: Effects of a temporary mass lesion
8. Mechanisms of delayed cell death following hypoxic-ischemic injury in the immature rat: Evidence for apoptosis during selective neuronal loss
9. Apoptotic DNA fragmentation in the rat cortex induced by permanent middle cerebral artery occlusion
10. Cell death: The significance of apoptosis
11. Treatment of elevated intracranial pressure in experimental intracerebral hemorrhage: Comparison between mannitol and hypertonic saline
12. Pharmacologic reduction of mean arterial pressure does not adversely affect regional cerebral blood flow and intracranial pressure in experimental intracerebral hemorrhage
13. Intact, injured, necrotic, and apoptotic cells after focal cerebral ischemia in the rat
14. Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat
15. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
16. Intracerebral hemorrhage in a primate model: Effect on regional cerebral blood flow
17. Experimental intracerebral mass: Time related effects on local cerebral blood flow
18. Intracranial hemorrhage induced at arterial pressure: Part 2. Short term changes in local cerebral blood flow measured by autoradiogtraphy
19. Effects of experimental intracerebral hemorrhage on blood flow, capillary permeability, and histochemistry
20. Early hemodynamic changes in experimental intracerebral hemorrhage
21. Effects of experimental intracerebral hemorrhage on blood flow, capillary permeability, and histochemistry
22. Experimental intracerebral hemorrhage: Progression of hemodynamic changes after production of a spontaneous mass lesion
23. Cerebral blood flow after experimental basal ganglia hemorrhage
24. Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat
25. Experimental intracerebral hemorrhage: Relationship between brain edema, blood flow, and blood-brain barrier permeability in rats
26. Ultra-early evaluation of intracerebral hemorrhage
27. Early hemorrhage growth in patients with intracerebral hemorrhage
28. Progression of hypertensive intracerebral hemorrhage
29. Enlargement of spontaneous intracerebral hemorrhage. Incidence and time course
30. Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat
31. The evolution of brain infarcts. A review
32. Myocardial ishemia: The pathogenesis of irreversible cell injury in ischemia
33. Experimental intracerebral hemorrhage: Early removal of a spontaneous mass lesion improves late outcome
34. Cerebral blood flow is symmetrically reduced in patients with intracerebral hemorrhage
35. Lobar intracerebral hemorrhage model in pigs: Rapid edema development in perihematoma white matter
36. The role of the coagulation cascade in brain edema formation after intracerebral hemorrhage
37. Mechanism of edema formation after intracerebral hemorrhage: Effects of thrombin on cerebral blood flow, blood-brain barrier permeability, and cell survival in a rat model
38. Expression of tissue necrosis factor in the cerebrospinal fluid after experimental intracerebral hemorrhage
39. The effect of immunosuppression on the development of cerebral oedema in an experimental model of intracerebral hemorrhage: Whole body and regional irradiation
40. Histologic sectioning produces TUNEL reactivity: A potential cause of false-positive staining