A synthetic Nitraria alkaloid, isonitramine protects pancreatic β-cell and attenuates postprandial hyperglycemia

Metabolism: Clinical and Experimental

Volumn 70, Issue , 2017, Pages 107-115

  Kwon, So Jung ^a   Hwang, Su Jung ^a   Jung, Yeonghun ^a   Park, Hyeung geun ^b   Kim, Mi hyun ^c   Park, Yohan ^a   Lee, Hyo Jong ^a  

^a Inje University   (South Korea)

^b Seoul National University   (South Korea)

^c Gachon University   (South Korea)

Author keywords

Diabetes mellitus; Insulin; Isonitramine; PEPCK; amylase; glucosidase

Indexed keywords

ALKALOID; ALLOXAN; ALPHA GLUCOSIDASE; AMYLASE; ANTIDIABETIC AGENT; CARBOHYDRATE; INSULIN; ISONITRAMINE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ANILINE DERIVATIVE; GLYCOSIDASE INHIBITOR; NITRAMINE; NITROBENZENE DERIVATIVE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PLANT EXTRACT; PROTECTIVE AGENT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARBOHYDRATE METABOLISM; CATABOLISM; CATALYSIS; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; DIABETES MELLITUS; DOWN REGULATION; DPPH RADICAL SCAVENGING ASSAY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG SAFETY; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GLUCONEOGENESIS; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; MALE; NITRARIACEAE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; POSTPRANDIAL STATE; PRIORITY JOURNAL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SURVIVAL RATE; ZEBRA FISH; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; HAMSTER; HUMAN; ISOLATION AND PURIFICATION; PIG; RAT;

ALKALOIDS; ANILINE COMPOUNDS; ANIMALS; CARBOHYDRATE METABOLISM; CELL LINE; CRICETINAE; GLYCOSIDE HYDROLASE INHIBITORS; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN-SECRETING CELLS; NITROBENZENES; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PLANT EXTRACTS; PROTECTIVE AGENTS; RATS; SWINE; ZEBRAFISH;

EID: 85014029751     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2017.02.002     Document Type: Article

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