메뉴 건너뛰기




Volumn 77, Issue 5, 2017, Pages

Inflammasome assembly in the chorioamniotic membranes during spontaneous labor at term

Author keywords

acute chorioamnionitis; apoptosis associated speck like protein containing a CARD (ASC); ASC speck; caspase 1; interleukin 1 beta; intra amniotic infection inflammation

Indexed keywords

CASP 1 PROTEIN; INFLAMMASOME; PROTEIN; UNCLASSIFIED DRUG;

EID: 85013682294     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/aji.12648     Document Type: Article
Times cited : (34)

References (100)
  • 1
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002;10:417–426.
    • (2002) Mol Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 2
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity. 2004;20:319–325.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 4
    • 33747191203 scopus 로고    scopus 로고
    • The inflammasome: first line of the immune response to cell stress
    • Ogura Y, Sutterwala FS, Flavell RA. The inflammasome: first line of the immune response to cell stress. Cell. 2006;126:659–662.
    • (2006) Cell , vol.126 , pp. 659-662
    • Ogura, Y.1    Sutterwala, F.S.2    Flavell, R.A.3
  • 6
    • 60749104683 scopus 로고    scopus 로고
    • The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
    • Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G. The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol. 2009;10:241–247.
    • (2009) Nat Immunol , vol.10 , pp. 241-247
    • Franchi, L.1    Eigenbrod, T.2    Munoz-Planillo, R.3    Nunez, G.4
  • 7
    • 76249102596 scopus 로고    scopus 로고
    • Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases
    • Jha S, Ting JP. Inflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseases. J Immunol. 2009;183:7623–7629.
    • (2009) J Immunol , vol.183 , pp. 7623-7629
    • Jha, S.1    Ting, J.P.2
  • 8
    • 64049096349 scopus 로고    scopus 로고
    • Sensing pathogens and danger signals by the inflammasome
    • Pedra JH, Cassel SL, Sutterwala FS. Sensing pathogens and danger signals by the inflammasome. Curr Opin Immunol. 2009;21:10–16.
    • (2009) Curr Opin Immunol , vol.21 , pp. 10-16
    • Pedra, J.H.1    Cassel, S.L.2    Sutterwala, F.S.3
  • 9
    • 79960502623 scopus 로고    scopus 로고
    • Modulation of inflammasome pathways by bacterial and viral pathogens
    • Lamkanfi M, Dixit VM. Modulation of inflammasome pathways by bacterial and viral pathogens. J Immunol. 2011;187:597–602.
    • (2011) J Immunol , vol.187 , pp. 597-602
    • Lamkanfi, M.1    Dixit, V.M.2
  • 11
    • 84858677223 scopus 로고    scopus 로고
    • Sensing and reacting to microbes through the inflammasomes
    • Franchi L, Munoz-Planillo R, Nunez G. Sensing and reacting to microbes through the inflammasomes. Nat Immunol. 2012;13:325–332.
    • (2012) Nat Immunol , vol.13 , pp. 325-332
    • Franchi, L.1    Munoz-Planillo, R.2    Nunez, G.3
  • 12
    • 84878237993 scopus 로고    scopus 로고
    • Activation and regulation of the inflammasomes
    • Latz E, Xiao TS, Stutz A. Activation and regulation of the inflammasomes. Nat Rev Immunol. 2013;13:397–411.
    • (2013) Nat Rev Immunol , vol.13 , pp. 397-411
    • Latz, E.1    Xiao, T.S.2    Stutz, A.3
  • 13
    • 84928050252 scopus 로고    scopus 로고
    • Mechanisms of inflammasome activation: recent advances and novel insights
    • Vanaja SK, Rathinam VA, Fitzgerald KA. Mechanisms of inflammasome activation: recent advances and novel insights. Trends Cell Biol. 2015;25:308–315.
    • (2015) Trends Cell Biol. , vol.25 , pp. 308-315
    • Vanaja, S.K.1    Rathinam, V.A.2    Fitzgerald, K.A.3
  • 14
    • 84936891896 scopus 로고    scopus 로고
    • Inflammasomes: mechanism of action, role in disease, and therapeutics
    • Guo H, Callaway JB, Ting JP. Inflammasomes: mechanism of action, role in disease, and therapeutics. Nat Med. 2015;21:677–687.
    • (2015) Nat Med , vol.21 , pp. 677-687
    • Guo, H.1    Callaway, J.B.2    Ting, J.P.3
  • 15
    • 0033607768 scopus 로고    scopus 로고
    • ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells
    • Masumoto J, Taniguchi S, Ayukawa K, et al. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. J Biol Chem. 1999;274:33835–33838.
    • (1999) J Biol Chem , vol.274 , pp. 33835-33838
    • Masumoto, J.1    Taniguchi, S.2    Ayukawa, K.3
  • 16
    • 0034804347 scopus 로고    scopus 로고
    • Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC
    • Masumoto J, Taniguchi S, Sagara J. Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC. Biochem Biophys Res Commun. 2001;280:652–655.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 652-655
    • Masumoto, J.1    Taniguchi, S.2    Sagara, J.3
  • 17
    • 84871314266 scopus 로고    scopus 로고
    • Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein
    • Vajjhala PR, Mirams RE, Hill JM. Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein. J Biol Chem. 2012;287:41732–41743.
    • (2012) J Biol Chem , vol.287 , pp. 41732-41743
    • Vajjhala, P.R.1    Mirams, R.E.2    Hill, J.M.3
  • 18
    • 34548031870 scopus 로고    scopus 로고
    • The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
    • Fernandes-Alnemri T, Wu J, Yu JW, et al. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 2007;14:1590–1604.
    • (2007) Cell Death Differ , vol.14 , pp. 1590-1604
    • Fernandes-Alnemri, T.1    Wu, J.2    Yu, J.W.3
  • 20
    • 0024551325 scopus 로고
    • A pre-aspartate-specific protease from human leukocytes that cleaves pro-interleukin-1 beta
    • Black RA, Kronheim SR, Merriam JE, March CJ, Hopp TP. A pre-aspartate-specific protease from human leukocytes that cleaves pro-interleukin-1 beta. J Biol Chem. 1989;264:5323–5326.
    • (1989) J Biol Chem , vol.264 , pp. 5323-5326
    • Black, R.A.1    Kronheim, S.R.2    Merriam, J.E.3    March, C.J.4    Hopp, T.P.5
  • 21
    • 0002928890 scopus 로고
    • Identification of a monocyte specific pre-interleukin 1 beta convertase activity
    • Kostura MJ, Tocci MJ, Limjuco G, et al. Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc Natl Acad Sci U S A. 1989;86:5227–5231.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 5227-5231
    • Kostura, M.J.1    Tocci, M.J.2    Limjuco, G.3
  • 22
    • 0026507126 scopus 로고
    • A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
    • Thornberry NA, Bull HG, Calaycay JR, et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature. 1992;356:768–774.
    • (1992) Nature , vol.356 , pp. 768-774
    • Thornberry, N.A.1    Bull, H.G.2    Calaycay, J.R.3
  • 23
    • 0028170376 scopus 로고
    • Structure and mechanism of interleukin-1 beta converting enzyme
    • Wilson KP, Black JA, Thomson JA, et al. Structure and mechanism of interleukin-1 beta converting enzyme. Nature. 1994;370:270–275.
    • (1994) Nature , vol.370 , pp. 270-275
    • Wilson, K.P.1    Black, J.A.2    Thomson, J.A.3
  • 24
    • 15644369352 scopus 로고    scopus 로고
    • Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
    • Gu Y, Kuida K, Tsutsui H, et al. Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science. 1997;275:206–209.
    • (1997) Science , vol.275 , pp. 206-209
    • Gu, Y.1    Kuida, K.2    Tsutsui, H.3
  • 25
    • 0031004174 scopus 로고    scopus 로고
    • Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
    • Ghayur T, Banerjee S, Hugunin M, et al. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature. 1997;386:619–623.
    • (1997) Nature , vol.386 , pp. 619-623
    • Ghayur, T.1    Banerjee, S.2    Hugunin, M.3
  • 26
    • 0031739525 scopus 로고    scopus 로고
    • Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme
    • Dinarello CA. Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme. Ann N Y Acad Sci. 1998;856:1–11.
    • (1998) Ann N Y Acad Sci , vol.856 , pp. 1-11
    • Dinarello, C.A.1
  • 27
    • 0032909752 scopus 로고    scopus 로고
    • Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1)
    • Fantuzzi G, Dinarello CA. Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1). J Clin Immunol. 1999;19:1–11.
    • (1999) J Clin Immunol , vol.19 , pp. 1-11
    • Fantuzzi, G.1    Dinarello, C.A.2
  • 29
    • 18644368579 scopus 로고    scopus 로고
    • Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1
    • Grenier JM, Wang L, Manji GA, et al. Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. FEBS Lett. 2002;530:73–78.
    • (2002) FEBS Lett , vol.530 , pp. 73-78
    • Grenier, J.M.1    Wang, L.2    Manji, G.A.3
  • 30
    • 79959540809 scopus 로고    scopus 로고
    • A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
    • Chen GY, Liu M, Wang F, Bertin J, Nunez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol. 2011;186:7187–7194.
    • (2011) J Immunol , vol.186 , pp. 7187-7194
    • Chen, G.Y.1    Liu, M.2    Wang, F.3    Bertin, J.4    Nunez, G.5
  • 31
    • 20444442787 scopus 로고    scopus 로고
    • PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion
    • Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T. PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem. 2005;280:21720–21725.
    • (2005) J Biol Chem , vol.280 , pp. 21720-21725
    • Kinoshita, T.1    Wang, Y.2    Hasegawa, M.3    Imamura, R.4    Suda, T.5
  • 32
    • 84858796861 scopus 로고    scopus 로고
    • An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages
    • Khare S, Dorfleutner A, Bryan NB, et al. An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity. 2012;36:464–476.
    • (2012) Immunity , vol.36 , pp. 464-476
    • Khare, S.1    Dorfleutner, A.2    Bryan, N.B.3
  • 33
    • 57149102672 scopus 로고    scopus 로고
    • NLRC4/IPAF: a CARD carrying member of the NLR family
    • Sutterwala FS, Flavell RA. NLRC4/IPAF: a CARD carrying member of the NLR family. Clin Immunol. 2009;130:2–6.
    • (2009) Clin Immunol , vol.130 , pp. 2-6
    • Sutterwala, F.S.1    Flavell, R.A.2
  • 34
    • 79956061094 scopus 로고    scopus 로고
    • IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection
    • Kerur N, Veettil MV, Sharma-Walia N, et al. IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection. Cell Host Microbe. 2011;9:363–375.
    • (2011) Cell Host Microbe , vol.9 , pp. 363-375
    • Kerur, N.1    Veettil, M.V.2    Sharma-Walia, N.3
  • 35
    • 60749136484 scopus 로고    scopus 로고
    • An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
    • Burckstummer T, Baumann C, Bluml S, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol. 2009;10:266–272.
    • (2009) Nat Immunol , vol.10 , pp. 266-272
    • Burckstummer, T.1    Baumann, C.2    Bluml, S.3
  • 36
    • 63649145255 scopus 로고    scopus 로고
    • AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
    • Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature. 2009;458:509–513.
    • (2009) Nature , vol.458 , pp. 509-513
    • Fernandes-Alnemri, T.1    Yu, J.W.2    Datta, P.3    Wu, J.4    Alnemri, E.S.5
  • 37
    • 60749104535 scopus 로고    scopus 로고
    • HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
    • Roberts TL, Idris A, Dunn JA, et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science. 2009;323:1057–1060.
    • (2009) Science , vol.323 , pp. 1057-1060
    • Roberts, T.L.1    Idris, A.2    Dunn, J.A.3
  • 38
    • 63649133278 scopus 로고    scopus 로고
    • AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
    • Hornung V, Ablasser A, Charrel-Dennis M, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature. 2009;458:514–518.
    • (2009) Nature , vol.458 , pp. 514-518
    • Hornung, V.1    Ablasser, A.2    Charrel-Dennis, M.3
  • 39
    • 77956498738 scopus 로고    scopus 로고
    • AIM2 joins the gang of microbial sensors
    • Franchi L, Nunez G. AIM2 joins the gang of microbial sensors. Cell Host Microbe. 2010;7:340–341.
    • (2010) Cell Host Microbe , vol.7 , pp. 340-341
    • Franchi, L.1    Nunez, G.2
  • 40
    • 84976329660 scopus 로고    scopus 로고
    • Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
    • Park YH, Wood G, Kastner DL, Chae JJ. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat Immunol. 2016;17:914–921.
    • (2016) Nat Immunol , vol.17 , pp. 914-921
    • Park, Y.H.1    Wood, G.2    Kastner, D.L.3    Chae, J.J.4
  • 41
    • 84976313489 scopus 로고    scopus 로고
    • Control of the innate immune response by the mevalonate pathway
    • Akula MK, Shi M, Jiang Z, et al. Control of the innate immune response by the mevalonate pathway. Nat Immunol. 2016;17:922–929.
    • (2016) Nat Immunol , vol.17 , pp. 922-929
    • Akula, M.K.1    Shi, M.2    Jiang, Z.3
  • 42
    • 84979599453 scopus 로고    scopus 로고
    • A dRAStic RHOAdblock of Pyrin inflammasome activation
    • Dorfleutner A, Stehlik C. A dRAStic RHOAdblock of Pyrin inflammasome activation. Nat Immunol. 2016;17:900–902.
    • (2016) Nat Immunol , vol.17 , pp. 900-902
    • Dorfleutner, A.1    Stehlik, C.2
  • 44
    • 70249138036 scopus 로고    scopus 로고
    • Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
    • Bauernfeind FG, Horvath G, Stutz A, et al. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol. 2009;183:787–791.
    • (2009) J Immunol , vol.183 , pp. 787-791
    • Bauernfeind, F.G.1    Horvath, G.2    Stutz, A.3
  • 45
    • 84959873222 scopus 로고    scopus 로고
    • A role for the inflammasome in spontaneous labor at term
    • [Epub ahead of print]
    • Romero R, Xu Y, Plazyo O, et al. A role for the inflammasome in spontaneous labor at term. Am J Reprod Immunol. 2016; doi: 10.1111/aji.12440. [Epub ahead of print].
    • (2016) Am J Reprod Immunol.
    • Romero, R.1    Xu, Y.2    Plazyo, O.3
  • 46
    • 85033376361 scopus 로고    scopus 로고
    • A role for the inflammasome in spontaneous labor at term with acute histologic chorioamnionitis
    • [Epub ahead of print]
    • Gomez-Lopez N, Romero R, Xu Y, et al. A role for the inflammasome in spontaneous labor at term with acute histologic chorioamnionitis. Reprod Sci. 2016; doi: 10.1177/1933719116675058. [Epub ahead of print].
    • (2016) Reprod Sci.
    • Gomez-Lopez, N.1    Romero, R.2    Xu, Y.3
  • 47
    • 85029294122 scopus 로고    scopus 로고
    • A role for the inflammasome in spontaneous preterm labor with acute histologic chorioamnionitis
    • [Epub ahead of print]
    • Gomez-Lopez N, Romero R, Xu Y, et al. A role for the inflammasome in spontaneous preterm labor with acute histologic chorioamnionitis. Reprod Sci. 2017; doi: 10.1177/193371911668765. [Epub ahead of print].
    • (2017) Reprod Sci.
    • Gomez-Lopez, N.1    Romero, R.2    Xu, Y.3
  • 48
    • 84919665779 scopus 로고    scopus 로고
    • A novel flow cytometric method to assess inflammasome formation
    • Sester DP, Thygesen SJ, Sagulenko V, et al. A novel flow cytometric method to assess inflammasome formation. J Immunol. 2015;194:455–462.
    • (2015) J Immunol , vol.194 , pp. 455-462
    • Sester, D.P.1    Thygesen, S.J.2    Sagulenko, V.3
  • 49
    • 84942586832 scopus 로고    scopus 로고
    • Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
    • Kim CJ, Romero R, Chaemsaithong P, Chaiyasit N, Yoon BH, Kim YM. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. Am J Obstet Gynecol. 2015;213:S29–S52.
    • (2015) Am J Obstet Gynecol , vol.213 , pp. S29-S52
    • Kim, C.J.1    Romero, R.2    Chaemsaithong, P.3    Chaiyasit, N.4    Yoon, B.H.5    Kim, Y.M.6
  • 50
    • 84942596721 scopus 로고    scopus 로고
    • Classification of placental lesions
    • Redline RW. Classification of placental lesions. Am J Obstet Gynecol. 2015;213:S21–S28.
    • (2015) Am J Obstet Gynecol , vol.213 , pp. S21-S28
    • Redline, R.W.1
  • 53
    • 33746479025 scopus 로고    scopus 로고
    • Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature
    • Haddad R, Tromp G, Kuivaniemi H, et al. Human spontaneous labor without histologic chorioamnionitis is characterized by an acute inflammation gene expression signature. Am J Obstet Gynecol. 2006;195:394. e391-324.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 394
    • Haddad, R.1    Tromp, G.2    Kuivaniemi, H.3
  • 54
    • 33747894504 scopus 로고    scopus 로고
    • The transcriptome of the uterine cervix before and after spontaneous term parturition
    • Hassan SS, Romero R, Haddad R, et al. The transcriptome of the uterine cervix before and after spontaneous term parturition. Am J Obstet Gynecol. 2006;195:778–786.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 778-786
    • Hassan, S.S.1    Romero, R.2    Haddad, R.3
  • 55
    • 39649111990 scopus 로고    scopus 로고
    • Inflammation in pregnancy: its roles in reproductive physiology, obstetrical complications, and fetal injury
    • Romero R, Gotsch F, Pineles B, Kusanovic JP. Inflammation in pregnancy: its roles in reproductive physiology, obstetrical complications, and fetal injury. Nutr Rev. 2007;65:S194–S202.
    • (2007) Nutr Rev , vol.65 , pp. S194-S202
    • Romero, R.1    Gotsch, F.2    Pineles, B.3    Kusanovic, J.P.4
  • 56
    • 78650135507 scopus 로고    scopus 로고
    • Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term
    • Mittal P, Romero R, Tarca AL, et al. Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term. J Perinat Med. 2010;38:617–643.
    • (2010) J Perinat Med , vol.38 , pp. 617-643
    • Mittal, P.1    Romero, R.2    Tarca, A.L.3
  • 58
    • 0027216880 scopus 로고
    • Microbial invasion of the amniotic cavity during term labor. Prevalence and clinical significance
    • Romero R, Nores J, Mazor M, et al. Microbial invasion of the amniotic cavity during term labor. Prevalence and clinical significance. J Reprod Med. 1993;38:543–548.
    • (1993) J Reprod Med , vol.38 , pp. 543-548
    • Romero, R.1    Nores, J.2    Mazor, M.3
  • 59
    • 52949150463 scopus 로고    scopus 로고
    • The frequency of microbial invasion of the amniotic cavity and histologic chorioamnionitis in women at term with intact membranes in the presence or absence of labor
    • Seong HS, Lee SE, Kang JH, Romero R, Yoon BH. The frequency of microbial invasion of the amniotic cavity and histologic chorioamnionitis in women at term with intact membranes in the presence or absence of labor. Am J Obstet Gynecol. 2008;199:375. e371-375.
    • (2008) Am J Obstet Gynecol , vol.199 , pp. 375
    • Seong, H.S.1    Lee, S.E.2    Kang, J.H.3    Romero, R.4    Yoon, B.H.5
  • 60
    • 0024307426 scopus 로고
    • Infection and labor. III. Interleukin-1: a signal for the onset of parturition
    • Romero R, Brody DT, Oyarzun E, et al. Infection and labor. III. Interleukin-1: a signal for the onset of parturition. Am J Obstet Gynecol. 1989;160:1117–1123.
    • (1989) Am J Obstet Gynecol , vol.160 , pp. 1117-1123
    • Romero, R.1    Brody, D.T.2    Oyarzun, E.3
  • 61
    • 0025231891 scopus 로고
    • Amniotic fluid interleukin-1 in spontaneous labor at term
    • Romero R, Parvizi ST, Oyarzun E, et al. Amniotic fluid interleukin-1 in spontaneous labor at term. J Reprod Med. 1990;35:235–238.
    • (1990) J Reprod Med , vol.35 , pp. 235-238
    • Romero, R.1    Parvizi, S.T.2    Oyarzun, E.3
  • 62
    • 0026774625 scopus 로고
    • Interleukin-1 alpha and interleukin-1 beta in preterm and term human parturition
    • Romero R, Mazor M, Brandt F, et al. Interleukin-1 alpha and interleukin-1 beta in preterm and term human parturition. Am J Reprod Immunol. 1992;27:117–123.
    • (1992) Am J Reprod Immunol , vol.27 , pp. 117-123
    • Romero, R.1    Mazor, M.2    Brandt, F.3
  • 63
    • 0026738960 scopus 로고
    • The natural interleukin-1 receptor antagonist in term and preterm parturition
    • Romero R, Sepulveda W, Mazor M, et al. The natural interleukin-1 receptor antagonist in term and preterm parturition. Am J Obstet Gynecol. 1992;167:863–872.
    • (1992) Am J Obstet Gynecol , vol.167 , pp. 863-872
    • Romero, R.1    Sepulveda, W.2    Mazor, M.3
  • 64
    • 0028149103 scopus 로고
    • The natural interleukin-1 receptor antagonist in the fetal, maternal, and amniotic fluid compartments: the effect of gestational age, fetal gender, and intrauterine infection
    • Romero R, Gomez R, Galasso M, et al. The natural interleukin-1 receptor antagonist in the fetal, maternal, and amniotic fluid compartments: the effect of gestational age, fetal gender, and intrauterine infection. Am J Obstet Gynecol. 1994;171:912–921.
    • (1994) Am J Obstet Gynecol , vol.171 , pp. 912-921
    • Romero, R.1    Gomez, R.2    Galasso, M.3
  • 66
    • 0027180113 scopus 로고
    • Tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy
    • Opsjln SL, Wathen NC, Tingulstad S, et al. Tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy. Am J Obstet Gynecol. 1993;169:397–404.
    • (1993) Am J Obstet Gynecol , vol.169 , pp. 397-404
    • Opsjln, S.L.1    Wathen, N.C.2    Tingulstad, S.3
  • 67
    • 0032738714 scopus 로고    scopus 로고
    • The tumor necrosis factor alpha and its soluble receptor profile in term and preterm parturition
    • Maymon E, Ghezzi F, Edwin SS, et al. The tumor necrosis factor alpha and its soluble receptor profile in term and preterm parturition. Am J Obstet Gynecol. 1999;181:1142–1148.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 1142-1148
    • Maymon, E.1    Ghezzi, F.2    Edwin, S.S.3
  • 68
    • 0027401621 scopus 로고
    • Elevation of amniotic fluid interleukin 6 (IL-6), IL-8 and granulocyte colony stimulating factor (G-CSF) in term and preterm parturition
    • Saito S, Kasahara T, Kato Y, Ishihara Y, Ichijo M. Elevation of amniotic fluid interleukin 6 (IL-6), IL-8 and granulocyte colony stimulating factor (G-CSF) in term and preterm parturition. Cytokine. 1993;5:81–88.
    • (1993) Cytokine , vol.5 , pp. 81-88
    • Saito, S.1    Kasahara, T.2    Kato, Y.3    Ishihara, Y.4    Ichijo, M.5
  • 69
    • 0029166776 scopus 로고
    • Amniotic fluid interleukin-6: correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated delivery
    • Andrews WW, Hauth JC, Goldenberg RL, Gomez R, Romero R, Cassell GH. Amniotic fluid interleukin-6: correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated delivery. Am J Obstet Gynecol. 1995;173:606–612.
    • (1995) Am J Obstet Gynecol , vol.173 , pp. 606-612
    • Andrews, W.W.1    Hauth, J.C.2    Goldenberg, R.L.3    Gomez, R.4    Romero, R.5    Cassell, G.H.6
  • 70
    • 0025940386 scopus 로고
    • Neutrophil attractant/activating peptide-1/interleukin-8 in term and preterm parturition
    • Romero R, Ceska M, Avila C, Mazor M, Behnke E, Lindley I. Neutrophil attractant/activating peptide-1/interleukin-8 in term and preterm parturition. Am J Obstet Gynecol. 1991;165:813–820.
    • (1991) Am J Obstet Gynecol , vol.165 , pp. 813-820
    • Romero, R.1    Ceska, M.2    Avila, C.3    Mazor, M.4    Behnke, E.5    Lindley, I.6
  • 71
    • 0030297192 scopus 로고    scopus 로고
    • Interleukin-6, interferon-gamma, interleukin-8, and granulocyte-macrophage colony stimulating factor levels in human amniotic fluid at term
    • Olah KS, Vince GS, Neilson JP, Deniz G, Johnson PM. Interleukin-6, interferon-gamma, interleukin-8, and granulocyte-macrophage colony stimulating factor levels in human amniotic fluid at term. J Reprod Immunol. 1996;32:89–98.
    • (1996) J Reprod Immunol , vol.32 , pp. 89-98
    • Olah, K.S.1    Vince, G.S.2    Neilson, J.P.3    Deniz, G.4    Johnson, P.M.5
  • 72
    • 0028172688 scopus 로고
    • Macrophage inflammatory protein-1 alpha in term and preterm parturition: effect of microbial invasion of the amniotic cavity
    • Romero R, Gomez R, Galasso M, et al. Macrophage inflammatory protein-1 alpha in term and preterm parturition: effect of microbial invasion of the amniotic cavity. Am J Reprod Immunol. 1994;32:108–113.
    • (1994) Am J Reprod Immunol , vol.32 , pp. 108-113
    • Romero, R.1    Gomez, R.2    Galasso, M.3
  • 73
    • 0030023356 scopus 로고    scopus 로고
    • Elevations of amniotic fluid macrophage inflammatory protein-1 alpha concentrations in women during term and preterm labor
    • Dudley DJ, Hunter C, Mitchell MD, Varner MW. Elevations of amniotic fluid macrophage inflammatory protein-1 alpha concentrations in women during term and preterm labor. Obstet Gynecol. 1996;87:94–98.
    • (1996) Obstet Gynecol , vol.87 , pp. 94-98
    • Dudley, D.J.1    Hunter, C.2    Mitchell, M.D.3    Varner, M.W.4
  • 74
    • 0037898354 scopus 로고    scopus 로고
    • Amniotic fluid levels of immunoreactive monocyte chemotactic protein-1 increase during term parturition
    • Esplin MS, Romero R, Chaiworapongsa T, et al. Amniotic fluid levels of immunoreactive monocyte chemotactic protein-1 increase during term parturition. J Matern Fetal Neonatal Med. 2003;14:51–56.
    • (2003) J Matern Fetal Neonatal Med , vol.14 , pp. 51-56
    • Esplin, M.S.1    Romero, R.2    Chaiworapongsa, T.3
  • 75
    • 0032721709 scopus 로고    scopus 로고
    • A role for the novel cytokine RANTES in pregnancy and parturition
    • Athayde N, Romero R, Maymon E, et al. A role for the novel cytokine RANTES in pregnancy and parturition. Am J Obstet Gynecol. 1999;181:989–994.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 989-994
    • Athayde, N.1    Romero, R.2    Maymon, E.3
  • 76
    • 49749098546 scopus 로고    scopus 로고
    • The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: a role for interleukin-10
    • Gotsch F, Romero R, Kusanovic JP, et al. The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: a role for interleukin-10. J Matern Fetal Neonatal Med. 2008;21:529–547.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , pp. 529-547
    • Gotsch, F.1    Romero, R.2    Kusanovic, J.P.3
  • 77
    • 44949131585 scopus 로고    scopus 로고
    • Exodus-1 (CCL20): evidence for the participation of this chemokine in spontaneous labor at term, preterm labor, and intrauterine infection
    • Hamill N, Romero R, Gotsch F, et al. Exodus-1 (CCL20): evidence for the participation of this chemokine in spontaneous labor at term, preterm labor, and intrauterine infection. J Perinat Med. 2008;36:217–227.
    • (2008) J Perinat Med , vol.36 , pp. 217-227
    • Hamill, N.1    Romero, R.2    Gotsch, F.3
  • 79
    • 85023166628 scopus 로고    scopus 로고
    • Clinical chorioamnionitis at term VII: the amniotic fluid cellular immune response
    • [Epub ahead of print]
    • Martinez-Varea A, Romero R, Xu Y, et al. Clinical chorioamnionitis at term VII: the amniotic fluid cellular immune response. J Perinat Med. 2016; doi: 10.1515/jpm-2016-0225. [Epub ahead of print].
    • (2016) J Perinat Med.
    • Martinez-Varea, A.1    Romero, R.2    Xu, Y.3
  • 80
    • 0033376686 scopus 로고    scopus 로고
    • Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition
    • Keelan JA, Marvin KW, Sato TA, Coleman M, McCowan LM, Mitchell MD. Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition. Am J Obstet Gynecol. 1999;181:1530–1536.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 1530-1536
    • Keelan, J.A.1    Marvin, K.W.2    Sato, T.A.3    Coleman, M.4    McCowan, L.M.5    Mitchell, M.D.6
  • 82
    • 0026000792 scopus 로고
    • Systemic administration of interleukin-1 induces preterm parturition in mice
    • Romero R, Mazor M, Tartakovsky B. Systemic administration of interleukin-1 induces preterm parturition in mice. Am J Obstet Gynecol. 1991;165:969–971.
    • (1991) Am J Obstet Gynecol , vol.165 , pp. 969-971
    • Romero, R.1    Mazor, M.2    Tartakovsky, B.3
  • 84
    • 0028598869 scopus 로고
    • Induction of interleukin-1 receptor antagonist in rhesus monkeys after intraamniotic infection with group B streptococci or interleukin-1 infusion
    • Witkin SS, Gravett MG, Haluska GJ, Novy MJ. Induction of interleukin-1 receptor antagonist in rhesus monkeys after intraamniotic infection with group B streptococci or interleukin-1 infusion. Am J Obstet Gynecol. 1994;171:1668–1672.
    • (1994) Am J Obstet Gynecol , vol.171 , pp. 1668-1672
    • Witkin, S.S.1    Gravett, M.G.2    Haluska, G.J.3    Novy, M.J.4
  • 87
    • 0034746240 scopus 로고    scopus 로고
    • Interleukin-1beta-induced prostaglandin E2 production in human myometrial cells: role of a pertussis toxin-sensitive component
    • Hertelendy F, Rastogi P, Molnar M, Romero R. Interleukin-1beta-induced prostaglandin E2 production in human myometrial cells: role of a pertussis toxin-sensitive component. Am J Reprod Immunol. 2001;45:142–147.
    • (2001) Am J Reprod Immunol , vol.45 , pp. 142-147
    • Hertelendy, F.1    Rastogi, P.2    Molnar, M.3    Romero, R.4
  • 88
    • 0032843860 scopus 로고    scopus 로고
    • The nuclear transcription factor NF-kappaB mediates interleukin-1beta-induced expression of cyclooxygenase-2 in human myometrial cells
    • Belt AR, Baldassare JJ, Molnar M, Romero R, Hertelendy F. The nuclear transcription factor NF-kappaB mediates interleukin-1beta-induced expression of cyclooxygenase-2 in human myometrial cells. Am J Obstet Gynecol. 1999;181:359–366.
    • (1999) Am J Obstet Gynecol , vol.181 , pp. 359-366
    • Belt, A.R.1    Baldassare, J.J.2    Molnar, M.3    Romero, R.4    Hertelendy, F.5
  • 89
    • 0032983537 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines induce expression of matrix-metabolizing enzymes in human cervical smooth muscle cells
    • Watari M, Watari H, DiSanto ME, Chacko S, Shi GP, Strauss JF 3rd. Pro-inflammatory cytokines induce expression of matrix-metabolizing enzymes in human cervical smooth muscle cells. Am J Pathol. 1999;154:1755–1762.
    • (1999) Am J Pathol , vol.154 , pp. 1755-1762
    • Watari, M.1    Watari, H.2    DiSanto, M.E.3    Chacko, S.4    Shi, G.P.5    Strauss, J.F.6
  • 90
    • 77951961451 scopus 로고    scopus 로고
    • The inflammasome” in human parturition
    • Pineles BL, Romero R, Montenegro D, et al. “The inflammasome” in human parturition. Reprod Sci. 2007;14:59A.
    • (2007) Reprod Sci , vol.14 , pp. 59A
    • Pineles, B.L.1    Romero, R.2    Montenegro, D.3
  • 91
    • 53149086262 scopus 로고    scopus 로고
    • Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition
    • Gotsch F, Romero R, Chaiworapongsa T, et al. Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition. J Matern Fetal Neonatal Med. 2008;21:605–616.
    • (2008) J Matern Fetal Neonatal Med , vol.21 , pp. 605-616
    • Gotsch, F.1    Romero, R.2    Chaiworapongsa, T.3
  • 92
    • 0036157634 scopus 로고    scopus 로고
    • Immunolocalization of proinflammatory cytokines in myometrium, cervix, and fetal membranes during human parturition at term
    • Young A, Thomson AJ, Ledingham M, Jordan F, Greer IA, Norman JE. Immunolocalization of proinflammatory cytokines in myometrium, cervix, and fetal membranes during human parturition at term. Biol Reprod. 2002;66:445–449.
    • (2002) Biol Reprod , vol.66 , pp. 445-449
    • Young, A.1    Thomson, A.J.2    Ledingham, M.3    Jordan, F.4    Greer, I.A.5    Norman, J.E.6
  • 93
    • 0037215931 scopus 로고    scopus 로고
    • Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term
    • Osman I, Young A, Ledingham MA, et al. Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term. Mol Hum Reprod. 2003;9:41–45.
    • (2003) Mol Hum Reprod , vol.9 , pp. 41-45
    • Osman, I.1    Young, A.2    Ledingham, M.A.3
  • 94
    • 84874339724 scopus 로고    scopus 로고
    • Identification of chemokines associated with the recruitment of decidual leukocytes in human labour: potential novel targets for preterm labour
    • Hamilton SA, Tower CL, Jones RL. Identification of chemokines associated with the recruitment of decidual leukocytes in human labour: potential novel targets for preterm labour. PLoS ONE. 2013;8:e56946.
    • (2013) PLoS ONE , vol.8
    • Hamilton, S.A.1    Tower, C.L.2    Jones, R.L.3
  • 95
    • 84928319317 scopus 로고    scopus 로고
    • Transcriptomic profiling of human choriodecidua during term labor: inflammation as a key driver of labor
    • Stephen GL, Lui S, Hamilton SA, et al. Transcriptomic profiling of human choriodecidua during term labor: inflammation as a key driver of labor. Am J Reprod Immunol. 2015;73:36–55.
    • (2015) Am J Reprod Immunol , vol.73 , pp. 36-55
    • Stephen, G.L.1    Lui, S.2    Hamilton, S.A.3
  • 96
    • 84924358820 scopus 로고    scopus 로고
    • Chemotactic activity of gestational tissues through late pregnancy, term labor, and RU486-induced preterm labor in Guinea pigs
    • Gomez-Lopez N, Tong WC, Arenas-Hernandez M, et al. Chemotactic activity of gestational tissues through late pregnancy, term labor, and RU486-induced preterm labor in Guinea pigs. Am J Reprod Immunol. 2015;73:341–352.
    • (2015) Am J Reprod Immunol , vol.73 , pp. 341-352
    • Gomez-Lopez, N.1    Tong, W.C.2    Arenas-Hernandez, M.3
  • 97
    • 84935721598 scopus 로고    scopus 로고
    • The Role of Macrophages in Promoting and Maintaining Homeostasis at the Fetal-Maternal Interface
    • Svensson-Arvelund J, Ernerudh J. The Role of Macrophages in Promoting and Maintaining Homeostasis at the Fetal-Maternal Interface. Am J Reprod Immunol. 2015;74:100–109.
    • (2015) Am J Reprod Immunol , vol.74 , pp. 100-109
    • Svensson-Arvelund, J.1    Ernerudh, J.2
  • 98
    • 84962528886 scopus 로고    scopus 로고
    • An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment
    • Xu Y, Romero R, Miller D, et al. An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment. J Immunol. 2016;196:2476–2491.
    • (2016) J Immunol , vol.196 , pp. 2476-2491
    • Xu, Y.1    Romero, R.2    Miller, D.3
  • 99
    • 84977525863 scopus 로고    scopus 로고
    • The Role of Decidual Macrophages During Normal and Pathological Pregnancy
    • Ning F, Liu H, Lash GE. The Role of Decidual Macrophages During Normal and Pathological Pregnancy. Am J Reprod Immunol. 2016;75:298–309.
    • (2016) Am J Reprod Immunol , vol.75 , pp. 298-309
    • Ning, F.1    Liu, H.2    Lash, G.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.