-
1
-
-
30044445643
-
High-dimensional and large-scale phenotyping of yeast mutants
-
Ohya Y, Sese J, Yukawa M, Sano F, Nakatani Y, Saito TL, Saka A, Fukuda T, Ishihara S, Oka S, et al. High-dimensional and large-scale phenotyping of yeast mutants. Proc Natl Acad Sci U S A 2005;102:19015–19020.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 19015-19020
-
-
Ohya, Y.1
Sese, J.2
Yukawa, M.3
Sano, F.4
Nakatani, Y.5
Saito, T.L.6
Saka, A.7
Fukuda, T.8
Ishihara, S.9
Oka, S.10
-
2
-
-
0142184341
-
Global analysis of protein localization in budding yeast
-
Huh W-K, Falvo JV, Gerke LC, Carroll AS, Howson RW, Weissman JS, O'Shea EK. Global analysis of protein localization in budding yeast. Nature 2003;425:686–691.
-
(2003)
Nature
, vol.425
, pp. 686-691
-
-
Huh, W.-K.1
Falvo, J.V.2
Gerke, L.C.3
Carroll, A.S.4
Howson, R.W.5
Weissman, J.S.6
O'Shea, E.K.7
-
3
-
-
84897388152
-
Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins
-
Loo L-H, Laksameethanasan D, Tung Y-L. Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins. PLoS Comput Biol 2014;10:e1003504.
-
(2014)
PLoS Comput Biol
, vol.10
-
-
Loo, L.-H.1
Laksameethanasan, D.2
Tung, Y.-L.3
-
4
-
-
0038699587
-
Global protein function prediction from protein-protein interaction networks
-
Vazquez A, Flammini A, Maritan A, Vespignani A. Global protein function prediction from protein-protein interaction networks. Nat Biotechnol 2003;21:697–700.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 697-700
-
-
Vazquez, A.1
Flammini, A.2
Maritan, A.3
Vespignani, A.4
-
5
-
-
33745220278
-
Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise
-
Newman JRS, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, DeRisi JL, Weissman JS. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature 2006;441:840–846.
-
(2006)
Nature
, vol.441
, pp. 840-846
-
-
Newman, J.R.S.1
Ghaemmaghami, S.2
Ihmels, J.3
Breslow, D.K.4
Noble, M.5
DeRisi, J.L.6
Weissman, J.S.7
-
6
-
-
33645798851
-
The fluorescent toolbox for assessing protein location and function
-
Giepmans BNG, Adams SR, Ellisman MH, Tsien RY. The fluorescent toolbox for assessing protein location and function. Science 2006;312:217–224.
-
(2006)
Science
, vol.312
, pp. 217-224
-
-
Giepmans, B.N.G.1
Adams, S.R.2
Ellisman, M.H.3
Tsien, R.Y.4
-
7
-
-
78650034777
-
Towards a knowledge-based Human Protein Atlas
-
Uhlen M, Oksvold P, Fagerberg L, Lundberg E, Jonasson K, Forsberg M, Zwahlen M, Kampf C, Wester K, Hober S, et al. Towards a knowledge-based Human Protein Atlas. Nat Biotechnol 2010;28:1248–1250.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1248-1250
-
-
Uhlen, M.1
Oksvold, P.2
Fagerberg, L.3
Lundberg, E.4
Jonasson, K.5
Forsberg, M.6
Zwahlen, M.7
Kampf, C.8
Wester, K.9
Hober, S.10
-
8
-
-
34249027579
-
The Carnegie protein trap library: A versatile tool for drosophila developmental studies
-
Buszczak M, Paterno S, Lighthouse D, Bachman J, Planck J, Owen S, Skora AD, Nystul TG, Ohlstein B, Allen A, et al. The Carnegie protein trap library: A versatile tool for drosophila developmental studies. Genetics 2007;175:1505–1531.
-
(2007)
Genetics
, vol.175
, pp. 1505-1531
-
-
Buszczak, M.1
Paterno, S.2
Lighthouse, D.3
Bachman, J.4
Planck, J.5
Owen, S.6
Skora, A.D.7
Nystul, T.G.8
Ohlstein, B.9
Allen, A.10
-
9
-
-
57349097152
-
Dynamic proteomics of individual cancer cells in response to a drug
-
Cohen AA, Geva-Zatorsky N, Eden E, Frenkel-Morgenstern M, Issaeva I, Sigal A, Milo R, Cohen-Saidon C, Liron Y, Kam Z, et al. Dynamic proteomics of individual cancer cells in response to a drug. Science 2008;322:1511–1516.
-
(2008)
Science
, vol.322
, pp. 1511-1516
-
-
Cohen, A.A.1
Geva-Zatorsky, N.2
Eden, E.3
Frenkel-Morgenstern, M.4
Issaeva, I.5
Sigal, A.6
Milo, R.7
Cohen-Saidon, C.8
Liron, Y.9
Kam, Z.10
-
10
-
-
0032694167
-
A sampling of the yeast proteome
-
Futcher B, Latter GI, Monardo P, McLaughlin CS, Garrels JI. A sampling of the yeast proteome. Mol Cell Biol 1999;19:7357–7368.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7357-7368
-
-
Futcher, B.1
Latter, G.I.2
Monardo, P.3
McLaughlin, C.S.4
Garrels, J.I.5
-
11
-
-
33846165487
-
Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation
-
Lu P, Vogel C, Wang R, Yao X, Marcotte EM. Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation. Nat Biotechnol 2007;25:117–124.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 117-124
-
-
Lu, P.1
Vogel, C.2
Wang, R.3
Yao, X.4
Marcotte, E.M.5
-
12
-
-
0042671348
-
Fluorescence in situ hybridization: past, present and future
-
Levsky JM, Singer RH. Fluorescence in situ hybridization: past, present and future. J Cell Sci 2003;116:2833–2838.
-
(2003)
J Cell Sci
, vol.116
, pp. 2833-2838
-
-
Levsky, J.M.1
Singer, R.H.2
-
13
-
-
53349161901
-
Imaging individual mRNA molecules using multiple singly labeled probes
-
Raj A, van den Bogaard P, Rifkin SA, van Oudenaarden A, Tyagi S. Imaging individual mRNA molecules using multiple singly labeled probes. Nat Methods 2008;5:877–879.
-
(2008)
Nat Methods
, vol.5
, pp. 877-879
-
-
Raj, A.1
van den Bogaard, P.2
Rifkin, S.A.3
van Oudenaarden, A.4
Tyagi, S.5
-
15
-
-
84887115231
-
Image-based transcriptomics in thousands of single human cells at single-molecule resolution
-
Battich N, Stoeger T, Pelkmans L. Image-based transcriptomics in thousands of single human cells at single-molecule resolution. Nat Methods 2013;10:1127–1133.
-
(2013)
Nat Methods
, vol.10
, pp. 1127-1133
-
-
Battich, N.1
Stoeger, T.2
Pelkmans, L.3
-
16
-
-
84928395184
-
Spatially resolved, highly multiplexed RNA profiling in single cells
-
Chen KH, Boettiger AN, Moffitt JR, Wang S, Zhuang X. Spatially resolved, highly multiplexed RNA profiling in single cells. Science 2015;348:aaa6090.
-
(2015)
Science
, vol.348
, pp. aaa6090
-
-
Chen, K.H.1
Boettiger, A.N.2
Moffitt, J.R.3
Wang, S.4
Zhuang, X.5
-
17
-
-
84860661767
-
The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging
-
Cajigas IJ, Tushev G, Will TJ, tom Dieck S, Fuerst N, Schuman EM. The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging. Neuron 2012;74:453–466.
-
(2012)
Neuron
, vol.74
, pp. 453-466
-
-
Cajigas, I.J.1
Tushev, G.2
Will, T.J.3
tom Dieck, S.4
Fuerst, N.5
Schuman, E.M.6
-
18
-
-
34848918150
-
Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function
-
Lécuyer E, Yoshida H, Parthasarathy N, Alm C, Babak T, Cerovina T, Hughes TR, Tomancak P, Krause HM. Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell 2007;131:174–187.
-
(2007)
Cell
, vol.131
, pp. 174-187
-
-
Lécuyer, E.1
Yoshida, H.2
Parthasarathy, N.3
Alm, C.4
Babak, T.5
Cerovina, T.6
Hughes, T.R.7
Tomancak, P.8
Krause, H.M.9
-
19
-
-
34147115178
-
Transcript and protein expression profiles of the NCI-60 cancer cell panel: An integromic microarray study
-
Shankavaram UT, Reinhold WC, Nishizuka S, Major S, Morita D, Chary KK, Reimers MA, Scherf U, Kahn A, Dolginow D, et al. Transcript and protein expression profiles of the NCI-60 cancer cell panel: An integromic microarray study. Mol Cancer Ther 2007;6:820–832.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 820-832
-
-
Shankavaram, U.T.1
Reinhold, W.C.2
Nishizuka, S.3
Major, S.4
Morita, D.5
Chary, K.K.6
Reimers, M.A.7
Scherf, U.8
Kahn, A.9
Dolginow, D.10
-
20
-
-
79956322553
-
Global quantification of mammalian gene expression control
-
Schwanhäusser B, Busse D, Li N, Dittmar G, Schuchhardt J, Wolf J, Chen W, Selbach M. Global quantification of mammalian gene expression control. Nature 2011;473:337–342.
-
(2011)
Nature
, vol.473
, pp. 337-342
-
-
Schwanhäusser, B.1
Busse, D.2
Li, N.3
Dittmar, G.4
Schuchhardt, J.5
Wolf, J.6
Chen, W.7
Selbach, M.8
-
21
-
-
84885722700
-
Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines
-
Niepel M, Hafner M, Pace EA, Chung M, Chai DH, Zhou L, Schoeberl B, Sorger PK. Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines. Sci Signal 2013;6:ra84
-
(2013)
Sci Signal
, vol.6
, pp. ra84
-
-
Niepel, M.1
Hafner, M.2
Pace, E.A.3
Chung, M.4
Chai, D.H.5
Zhou, L.6
Schoeberl, B.7
Sorger, P.K.8
-
22
-
-
34250216344
-
Image-based multivariate profiling of drug responses from single cells
-
Loo L-H, Wu LF, Altschuler SJ. Image-based multivariate profiling of drug responses from single cells. Nat Methods 2007;4:445–453.
-
(2007)
Nat Methods
, vol.4
, pp. 445-453
-
-
Loo, L.-H.1
Wu, L.F.2
Altschuler, S.J.3
-
23
-
-
84863205689
-
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
-
Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché J-K, Neumann B, et al. Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nat Cell Biol 2012;14:764–774.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 764-774
-
-
Simpson, J.C.1
Joggerst, B.2
Laketa, V.3
Verissimo, F.4
Cetin, C.5
Erfle, H.6
Bexiga, M.G.7
Singan, V.R.8
Hériché, J.-K.9
Neumann, B.10
-
24
-
-
79960959180
-
RNA mimics of green fluorescent protein
-
Paige JS, Wu KY, Jaffrey SR. RNA mimics of green fluorescent protein. Science 2011;333:642–646.
-
(2011)
Science
, vol.333
, pp. 642-646
-
-
Paige, J.S.1
Wu, K.Y.2
Jaffrey, S.R.3
-
25
-
-
0033554060
-
Is green fluorescent protein toxic to the living cells?
-
Liu HS, Jan MS, Chou CK, Chen PH, Ke NJ. Is green fluorescent protein toxic to the living cells? Biochem Biophys Res Commun 1999;260:712–717.
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 712-717
-
-
Liu, H.S.1
Jan, M.S.2
Chou, C.K.3
Chen, P.H.4
Ke, N.J.5
-
26
-
-
84928141099
-
CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells
-
Ratz M, Testa I, Hell SW, Jakobs S. CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells. Sci Rep 2015;5:9592.
-
(2015)
Sci Rep
, vol.5
, pp. 9592
-
-
Ratz, M.1
Testa, I.2
Hell, S.W.3
Jakobs, S.4
-
27
-
-
84961226910
-
Programmable RNA tracking in live cells with CRISPR/Cas9
-
Nelles DA, Fang MY, O'Connell MR, Xu JL, Markmiller SJ, Doudna JA, Yeo GW. Programmable RNA tracking in live cells with CRISPR/Cas9. Cell 2016;165:488–496.
-
(2016)
Cell
, vol.165
, pp. 488-496
-
-
Nelles, D.A.1
Fang, M.Y.2
O'Connell, M.R.3
Xu, J.L.4
Markmiller, S.J.5
Doudna, J.A.6
Yeo, G.W.7
-
28
-
-
84903601874
-
Fluorogenic probes for live-cell imaging of the cytoskeleton
-
Lukinavičius G, Reymond L, D'Este E, Masharina A, Göttfert F, Ta H, Güther A, Fournier M, Rizzo S, Waldmann H, et al. Fluorogenic probes for live-cell imaging of the cytoskeleton. Nat Methods 2014;11:731–733.
-
(2014)
Nat Methods
, vol.11
, pp. 731-733
-
-
Lukinavičius, G.1
Reymond, L.2
D'Este, E.3
Masharina, A.4
Göttfert, F.5
Ta, H.6
Güther, A.7
Fournier, M.8
Rizzo, S.9
Waldmann, H.10
-
29
-
-
0034331004
-
Chemical genetics: Ligand-based discovery of gene function
-
Stockwell BR. Chemical genetics: Ligand-based discovery of gene function. Nat Rev Genet 2000;1:116–125.
-
(2000)
Nat Rev Genet
, vol.1
, pp. 116-125
-
-
Stockwell, B.R.1
-
30
-
-
0034677966
-
Drug discovery: A historical perspective
-
Drews J. Drug discovery: A historical perspective. Science 2000;287:1960–1964.
-
(2000)
Science
, vol.287
, pp. 1960-1964
-
-
Drews, J.1
-
32
-
-
84902210226
-
Increasing the content of high-content screening: An overview
-
Singh S, Carpenter AE, Genovesio A. Increasing the content of high-content screening: An overview. J Biomol Screen 2014;19:640–650.
-
(2014)
J Biomol Screen
, vol.19
, pp. 640-650
-
-
Singh, S.1
Carpenter, A.E.2
Genovesio, A.3
-
33
-
-
70350518100
-
Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases
-
Link W, Oyarzabal J, Serelde BG, Albarran MI, Rabal O, Cebriá A, Alfonso P, Fominaya J, Renner O, Peregrina S, et al. Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases. J Biol Chem 2009;284:28392–28400.
-
(2009)
J Biol Chem
, vol.284
, pp. 28392-28400
-
-
Link, W.1
Oyarzabal, J.2
Serelde, B.G.3
Albarran, M.I.4
Rabal, O.5
Cebriá, A.6
Alfonso, P.7
Fominaya, J.8
Renner, O.9
Peregrina, S.10
-
34
-
-
21744448078
-
An unbiased cell morphology-based screen for new, biologically active small molecules
-
Tanaka M, Bateman R, Rauh D, Vaisberg E, Ramachandani S, Zhang C, Hansen KC, Burlingame AL, Trautman JK, Shokat KM, et al. An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol 2005;3:e128.
-
(2005)
PLoS Biol
, vol.3
-
-
Tanaka, M.1
Bateman, R.2
Rauh, D.3
Vaisberg, E.4
Ramachandani, S.5
Zhang, C.6
Hansen, K.C.7
Burlingame, A.L.8
Trautman, J.K.9
Shokat, K.M.10
-
35
-
-
84922785429
-
High content image-based screening of a protease inhibitor library reveals compounds broadly active against rift valley fever virus and other highly pathogenic RNA viruses
-
Mudhasani R, Kota KP, Retterer C, Tran JP, Whitehouse CA, Bavari S. High content image-based screening of a protease inhibitor library reveals compounds broadly active against rift valley fever virus and other highly pathogenic RNA viruses. PLoS Negl Trop Dis 2014;8:e3095.
-
(2014)
PLoS Negl Trop Dis
, vol.8
-
-
Mudhasani, R.1
Kota, K.P.2
Retterer, C.3
Tran, J.P.4
Whitehouse, C.A.5
Bavari, S.6
-
36
-
-
84867055688
-
Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis
-
Schulz MMP, Reisen F, Zgraggen S, Fischer S, Yuen D, Kang GJ, Chen L, Schneider G, Detmar M. Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis. Proc Natl Acad Sci 2012;109:E2665–E2674.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. E2665-E2674
-
-
Schulz, M.M.P.1
Reisen, F.2
Zgraggen, S.3
Fischer, S.4
Yuen, D.5
Kang, G.J.6
Chen, L.7
Schneider, G.8
Detmar, M.9
-
37
-
-
8444223104
-
Multidimensional drug profiling by automated microscopy
-
Perlman ZE, Slack MD, Feng Y, Mitchison TJ, Wu LF, Altschuler SJ. Multidimensional drug profiling by automated microscopy. Science 2004;306:1194–1198.
-
(2004)
Science
, vol.306
, pp. 1194-1198
-
-
Perlman, Z.E.1
Slack, M.D.2
Feng, Y.3
Mitchison, T.J.4
Wu, L.F.5
Altschuler, S.J.6
-
38
-
-
84902166194
-
Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms
-
Kleinstreuer NC, Yang J, Berg EL, Knudsen TB, Richard AM, Martin MT, Reif DM, Judson RS, Polokoff M, Dix DJ, et al. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nat Biotechnol 2014;32:583–591.
-
(2014)
Nat Biotechnol
, vol.32
, pp. 583-591
-
-
Kleinstreuer, N.C.1
Yang, J.2
Berg, E.L.3
Knudsen, T.B.4
Richard, A.M.5
Martin, M.T.6
Reif, D.M.7
Judson, R.S.8
Polokoff, M.9
Dix, D.J.10
-
39
-
-
1642393941
-
Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid
-
Cleuvers M. Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid. Ecotoxicol Environ Saf 2004;59:309–315.
-
(2004)
Ecotoxicol Environ Saf
, vol.59
, pp. 309-315
-
-
Cleuvers, M.1
-
40
-
-
84991235141
-
High-throughput imaging-based nephrotoxicity prediction for xenobiotics with diverse chemical structures
-
Su R, Xiong S, Zink D, Loo L-H. High-throughput imaging-based nephrotoxicity prediction for xenobiotics with diverse chemical structures. Arch Toxicol 2015;1–16.
-
(2015)
Arch Toxicol
, pp. 1-16
-
-
Su, R.1
Xiong, S.2
Zink, D.3
Loo, L.-H.4
-
41
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
Hamilton AJ, Baulcombe DC. A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 1999;286:950–952.
-
(1999)
Science
, vol.286
, pp. 950-952
-
-
Hamilton, A.J.1
Baulcombe, D.C.2
-
42
-
-
34047118522
-
CRISPR provides acquired resistance against viruses in prokaryotes
-
Barrangou R, Fremaux C, Deveau H, Richards M, Boyaval P, Moineau S, Romero DA, Horvath P. CRISPR provides acquired resistance against viruses in prokaryotes. Science 2007;315:1709–1712.
-
(2007)
Science
, vol.315
, pp. 1709-1712
-
-
Barrangou, R.1
Fremaux, C.2
Deveau, H.3
Richards, M.4
Boyaval, P.5
Moineau, S.6
Romero, D.A.7
Horvath, P.8
-
43
-
-
84865070369
-
A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity. Science 2012;337:816–821.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
44
-
-
4544242851
-
Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
-
Kawasaki H, Taira K. Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature 2004;431:211–217.
-
(2004)
Nature
, vol.431
, pp. 211-217
-
-
Kawasaki, H.1
Taira, K.2
-
45
-
-
84908352138
-
Genome-scale CRISPR-mediated control of gene repression and activation
-
Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, et al. Genome-scale CRISPR-mediated control of gene repression and activation. Cell 2014;159:647–661.
-
(2014)
Cell
, vol.159
, pp. 647-661
-
-
Gilbert, L.A.1
Horlbeck, M.A.2
Adamson, B.3
Villalta, J.E.4
Chen, Y.5
Whitehead, E.H.6
Guimaraes, C.7
Panning, B.8
Ploegh, H.L.9
Bassik, M.C.10
-
46
-
-
33750887331
-
A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling
-
Friedman A, Perrimon N. A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature 2006;444:230–234.
-
(2006)
Nature
, vol.444
, pp. 230-234
-
-
Friedman, A.1
Perrimon, N.2
-
47
-
-
79955549678
-
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue
-
Green RA, Kao H-L, Audhya A, Arur S, Mayers JR, Fridolfsson HN, Schulman M, Schloissnig S, Niessen S, Laband K, et al. A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell 2011;145:470–482.
-
(2011)
Cell
, vol.145
, pp. 470-482
-
-
Green, R.A.1
Kao, H.-L.2
Audhya, A.3
Arur, S.4
Mayers, J.R.5
Fridolfsson, H.N.6
Schulman, M.7
Schloissnig, S.8
Niessen, S.9
Laband, K.10
-
48
-
-
84892765883
-
Genome-scale CRISPR-Cas9 knockout screening in human cells
-
Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 2014;343:84–87.
-
(2014)
Science
, vol.343
, pp. 84-87
-
-
Shalem, O.1
Sanjana, N.E.2
Hartenian, E.3
Shi, X.4
Scott, D.A.5
Mikkelsen, T.S.6
Heckl, D.7
Ebert, B.L.8
Root, D.E.9
Doench, J.G.10
Zhang, F.11
-
49
-
-
12144288006
-
A resource for large-scale RNA-interference-based screens in mammals
-
Paddison PJ, Silva JM, Conklin DS, Schlabach M, Li M, Aruleba S, Balija V, O'Shaughnessy A, Gnoj L, Scobie K, et al. A resource for large-scale RNA-interference-based screens in mammals. Nature 2004;428:427–431.
-
(2004)
Nature
, vol.428
, pp. 427-431
-
-
Paddison, P.J.1
Silva, J.M.2
Conklin, D.S.3
Schlabach, M.4
Li, M.5
Aruleba, S.6
Balija, V.7
O'Shaughnessy, A.8
Gnoj, L.9
Scobie, K.10
-
50
-
-
77950387346
-
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
-
Neumann B, Walter T, Hériché J-K, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, et al. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature 2010;464:721–727.
-
(2010)
Nature
, vol.464
, pp. 721-727
-
-
Neumann, B.1
Walter, T.2
Hériché, J.-K.3
Bulkescher, J.4
Erfle, H.5
Conrad, C.6
Rogers, P.7
Poser, I.8
Held, M.9
Liebel, U.10
-
51
-
-
51049121572
-
Identification of genes that regulate epithelial cell migration using an siRNA screening approach
-
Simpson KJ, Selfors LM, Bui J, Reynolds A, Leake D, Khvorova A, Brugge JS. Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nat Cell Biol 2008;10:1027–1038.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1027-1038
-
-
Simpson, K.J.1
Selfors, L.M.2
Bui, J.3
Reynolds, A.4
Leake, D.5
Khvorova, A.6
Brugge, J.S.7
-
52
-
-
21844440569
-
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis
-
Pelkmans L, Fava E, Grabner H, Hannus M, Habermann B, Krausz E, Zerial M. Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature 2005;436:78–86.
-
(2005)
Nature
, vol.436
, pp. 78-86
-
-
Pelkmans, L.1
Fava, E.2
Grabner, H.3
Hannus, M.4
Habermann, B.5
Krausz, E.6
Zerial, M.7
-
53
-
-
33646057010
-
High-throughput RNAi screening by time-lapse imaging of live human cells
-
Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J. High-throughput RNAi screening by time-lapse imaging of live human cells. Nat Methods 2006;3:385–390.
-
(2006)
Nat Methods
, vol.3
, pp. 385-390
-
-
Neumann, B.1
Held, M.2
Liebel, U.3
Erfle, H.4
Rogers, P.5
Pepperkok, R.6
Ellenberg, J.7
-
54
-
-
84974588043
-
Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes
-
Morgens DW, Deans RM, Li A, Bassik MC. Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes. Nat Biotechnol 2016;34:634–636.
-
(2016)
Nat Biotechnol
, vol.34
, pp. 634-636
-
-
Morgens, D.W.1
Deans, R.M.2
Li, A.3
Bassik, M.C.4
-
55
-
-
6344249316
-
Dynamics of gene silencing by RNA interference
-
Raab RM, Stephanopoulos G. Dynamics of gene silencing by RNA interference. Biotechnol Bioeng 2004;88:121–132.
-
(2004)
Biotechnol Bioeng
, vol.88
, pp. 121-132
-
-
Raab, R.M.1
Stephanopoulos, G.2
-
56
-
-
70350736762
-
Transcriptional effects of transfection: The potential for misinterpretation of gene expression data generated from transiently transfected cells
-
Jacobsen L, Calvin S, Lobenhofer E. Transcriptional effects of transfection: The potential for misinterpretation of gene expression data generated from transiently transfected cells. BioTechniques 2009;47:617–624.
-
(2009)
BioTechniques
, vol.47
, pp. 617-624
-
-
Jacobsen, L.1
Calvin, S.2
Lobenhofer, E.3
-
57
-
-
75149130051
-
Targeting the cancer kinome through polypharmacology
-
Knight ZA, Lin H, Shokat KM. Targeting the cancer kinome through polypharmacology. Nat Rev Cancer 2010;10:130–137.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 130-137
-
-
Knight, Z.A.1
Lin, H.2
Shokat, K.M.3
-
58
-
-
77149130553
-
Automated microscopy for high-content RNAi screening
-
Conrad C, Gerlich DW. Automated microscopy for high-content RNAi screening. J Cell Biol 2010;188:453–461.
-
(2010)
J Cell Biol
, vol.188
, pp. 453-461
-
-
Conrad, C.1
Gerlich, D.W.2
-
59
-
-
57049118570
-
A robotic platform for quantitative high-throughput screening
-
Michael S, Auld D, Klumpp C, Jadhav A, Zheng W, Thorne N, Austin CP, Inglese J, Simeonov A. A robotic platform for quantitative high-throughput screening. Assay Drug Dev Technol 2008;6:637–657.
-
(2008)
Assay Drug Dev Technol
, vol.6
, pp. 637-657
-
-
Michael, S.1
Auld, D.2
Klumpp, C.3
Jadhav, A.4
Zheng, W.5
Thorne, N.6
Austin, C.P.7
Inglese, J.8
Simeonov, A.9
-
60
-
-
33750811740
-
Digital autofocus methods for automated microscopy
-
Shen F, Hodgson L, Hahn K. Digital autofocus methods for automated microscopy. Methods Enzymol 2006;414:620–632.
-
(2006)
Methods Enzymol
, vol.414
, pp. 620-632
-
-
Shen, F.1
Hodgson, L.2
Hahn, K.3
-
61
-
-
33644749430
-
Laser autofocusing system for high-resolution cell biological imaging
-
Liron Y, Paran Y, Zatorsky NG, Geiger B, Kam Z. Laser autofocusing system for high-resolution cell biological imaging. J Microsc 2006;221:145–151.
-
(2006)
J Microsc
, vol.221
, pp. 145-151
-
-
Liron, Y.1
Paran, Y.2
Zatorsky, N.G.3
Geiger, B.4
Kam, Z.5
-
62
-
-
79952189489
-
Micropilot: Automation of fluorescence microscopy-based imaging for systems biology
-
Conrad C, Wünsche A, Tan TH, Bulkescher J, Sieckmann F, Verissimo F, Edelstein A, Walter T, Liebel U, Pepperkok R, et al. Micropilot: Automation of fluorescence microscopy-based imaging for systems biology. Nat Methods 2011;8:246–249.
-
(2011)
Nat Methods
, vol.8
, pp. 246-249
-
-
Conrad, C.1
Wünsche, A.2
Tan, T.H.3
Bulkescher, J.4
Sieckmann, F.5
Verissimo, F.6
Edelstein, A.7
Walter, T.8
Liebel, U.9
Pepperkok, R.10
-
63
-
-
84866423721
-
A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells
-
Mathews LA, Keller JM, Goodwin BL, Guha R, Shinn P, Mull R, Thomas CJ, Kluyver RL, de Sayers TJ, Ferrer M. A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells. J Biomol Screen 2012;17:1231–1242.
-
(2012)
J Biomol Screen
, vol.17
, pp. 1231-1242
-
-
Mathews, L.A.1
Keller, J.M.2
Goodwin, B.L.3
Guha, R.4
Shinn, P.5
Mull, R.6
Thomas, C.J.7
Kluyver, R.L.8
de Sayers, T.J.9
Ferrer, M.10
-
64
-
-
33644777646
-
Lab-on-a-chip: Microfluidics in drug discovery
-
Dittrich PS, Manz A. Lab-on-a-chip: Microfluidics in drug discovery. Nat Rev Drug Discov 2006;5:210–218.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 210-218
-
-
Dittrich, P.S.1
Manz, A.2
-
65
-
-
58849132813
-
Micro- and nanofluidic systems for high-throughput biological screening
-
Hong J, Edel JB, deMello AJ. Micro- and nanofluidic systems for high-throughput biological screening. Drug Discov Today 2009;14:134–146.
-
(2009)
Drug Discov Today
, vol.14
, pp. 134-146
-
-
Hong, J.1
Edel, J.B.2
deMello, A.J.3
-
66
-
-
67649612733
-
Accuracy and precision in quantitative fluorescence microscopy
-
Waters JC. Accuracy and precision in quantitative fluorescence microscopy. J Cell Biol 2009;185:1135–1148.
-
(2009)
J Cell Biol
, vol.185
, pp. 1135-1148
-
-
Waters, J.C.1
-
67
-
-
65649134709
-
Globally optimal stitching of tiled 3D microscopic image acquisitions
-
Preibisch S, Saalfeld S, Tomancak P. Globally optimal stitching of tiled 3D microscopic image acquisitions. Bioinformatics 2009;25:1463–1465.
-
(2009)
Bioinformatics
, vol.25
, pp. 1463-1465
-
-
Preibisch, S.1
Saalfeld, S.2
Tomancak, P.3
-
68
-
-
85032750965
-
Cell segmentation: 50 years down the road [life sciences]
-
Meijering E. Cell segmentation: 50 years down the road [life sciences]. IEEE Signal Process Mag 2012;29:140–145.
-
(2012)
IEEE Signal Process Mag
, vol.29
, pp. 140-145
-
-
Meijering, E.1
-
69
-
-
77949777061
-
Evolving generalized Voronoi diagrams for accurate cellular image segmentation
-
Yu W, Lee HK, Hariharan S, Bu W, Ahmed S. Evolving generalized Voronoi diagrams for accurate cellular image segmentation. Cytom Part J Int Soc Anal Cytol 2010;77:379–386.
-
(2010)
Cytom Part J Int Soc Anal Cytol
, vol.77
, pp. 379-386
-
-
Yu, W.1
Lee, H.K.2
Hariharan, S.3
Bu, W.4
Ahmed, S.5
-
70
-
-
65549100286
-
Quantitative neurite outgrowth measurement based on image segmentation with topological dependence
-
Yu W, Lee HK, Hariharan S, Bu W, Ahmed S. Quantitative neurite outgrowth measurement based on image segmentation with topological dependence. Cytometry Part A 2009;75A:289–297.
-
(2009)
Cytometry Part A
, vol.75A
, pp. 289-297
-
-
Yu, W.1
Lee, H.K.2
Hariharan, S.3
Bu, W.4
Ahmed, S.5
-
71
-
-
68649098966
-
Level set segmentation of cellular images based on topological dependence
-
In, Bebis G, Boyle R, Parvin B, Koracin D, Remagnino P, Porikli F, Peters J, Klosowski J, Arns L, Chun YK, Rhyne T-M, Monroe L, editors., Berlin-Heidelberg, Springer, pp
-
Yu W, Lee HK, Hariharan S, Bu W, Ahmed S. Level set segmentation of cellular images based on topological dependence. In: Bebis G, Boyle R, Parvin B, Koracin D, Remagnino P, Porikli F, Peters J, Klosowski J, Arns L, Chun YK, Rhyne T-M, Monroe L, editors. Advances in Visual Computing, Lecture Notes in Computer Science. Berlin-Heidelberg: Springer; 2008. pp 540–551.
-
(2008)
Advances in Visual Computing, Lecture Notes in Computer Science
, pp. 540-551
-
-
Yu, W.1
Lee, H.K.2
Hariharan, S.3
Bu, W.4
Ahmed, S.5
-
72
-
-
79957500803
-
A variational model for segmentation of overlapping objects with additive intensity value
-
Law YN, Lee HK, Liu C, Yip AM. A variational model for segmentation of overlapping objects with additive intensity value. IEEE Trans Image Process 2011;20:1495–1503.
-
(2011)
IEEE Trans Image Process
, vol.20
, pp. 1495-1503
-
-
Law, Y.N.1
Lee, H.K.2
Liu, C.3
Yip, A.M.4
-
73
-
-
78651233871
-
Automatic measurement of volume percentage stroma in endometrial images using texture segmentation
-
Law YN, Yip AM, Lee HK. Automatic measurement of volume percentage stroma in endometrial images using texture segmentation. J Microsc 2011;241:171–178.
-
(2011)
J Microsc
, vol.241
, pp. 171-178
-
-
Law, Y.N.1
Yip, A.M.2
Lee, H.K.3
-
74
-
-
62349114982
-
Automated protein distribution detection in high-throughput image-based siRNA library screens
-
Law YN, Ogg S, Common J, Tan D, Lane EB, Yip AM, Lee HK. Automated protein distribution detection in high-throughput image-based siRNA library screens. J Signal Process Syst 2008;55:1–13.
-
(2008)
J Signal Process Syst
, vol.55
, pp. 1-13
-
-
Law, Y.N.1
Ogg, S.2
Common, J.3
Tan, D.4
Lane, E.B.5
Yip, A.M.6
Lee, H.K.7
-
75
-
-
0000235184
-
High-speed automatic analysis of biomedical pictures
-
Ledley RS. High-speed automatic analysis of biomedical pictures. Science 1964;146:216–223.
-
(1964)
Science
, vol.146
, pp. 216-223
-
-
Ledley, R.S.1
-
77
-
-
70350700675
-
Plasma membrane and nuclear envelope integrity during the blebbing stage of apoptosis: A time-lapse study
-
Andrade R, Crisol L, Prado R, Boyano MD, Arluzea J, Aréchaga J. Plasma membrane and nuclear envelope integrity during the blebbing stage of apoptosis: A time-lapse study. Biol Cell Auspices Eur Cell Biol Organ 2010;102:25–35.
-
(2010)
Biol Cell Auspices Eur Cell Biol Organ
, vol.102
, pp. 25-35
-
-
Andrade, R.1
Crisol, L.2
Prado, R.3
Boyano, M.D.4
Arluzea, J.5
Aréchaga, J.6
-
78
-
-
4544306053
-
Measurement of apoptosis by DNA fragmentation
-
Matassov D, Kagan T, Leblanc J, Sikorska M, Zakeri Z. Measurement of apoptosis by DNA fragmentation. Methods Mol Biol Clifton NJ 2004;282:1–17.
-
(2004)
Methods Mol Biol Clifton NJ
, vol.282
, pp. 1-17
-
-
Matassov, D.1
Kagan, T.2
Leblanc, J.3
Sikorska, M.4
Zakeri, Z.5
-
79
-
-
0036591799
-
Measurement of nuclear factor-kappa B translocation on lipopolysaccharide-activated human dendritic cells by confocal microscopy and flow cytometry
-
Blaecke A, Delneste Y, Herbault N, Jeannin P, Bonnefoy J-Y, Beck A, Aubry J-P. Measurement of nuclear factor-kappa B translocation on lipopolysaccharide-activated human dendritic cells by confocal microscopy and flow cytometry. Cytometry 2002;48:71–79.
-
(2002)
Cytometry
, vol.48
, pp. 71-79
-
-
Blaecke, A.1
Delneste, Y.2
Herbault, N.3
Jeannin, P.4
Bonnefoy, J.-Y.5
Beck, A.6
Aubry, J.-P.7
-
80
-
-
0001341562
-
High-content screening: A new approach to easing key bottlenecks in the drug discovery process
-
Giuliano KA, DeBiasio RL, Dunlay RT, Gough A, Volosky JM, Zock J, Pavlakis GN, Taylor DL. High-content screening: A new approach to easing key bottlenecks in the drug discovery process. J Biomol Screen 1997;2:249–259.
-
(1997)
J Biomol Screen
, vol.2
, pp. 249-259
-
-
Giuliano, K.A.1
DeBiasio, R.L.2
Dunlay, R.T.3
Gough, A.4
Volosky, J.M.5
Zock, J.6
Pavlakis, G.N.7
Taylor, D.L.8
-
82
-
-
84863393849
-
OMERO: Flexible, model-driven data management for experimental biology
-
Allan C, Burel J-M, Moore J, Blackburn C, Linkert M, Loynton S, MacDonald D, Moore WJ, Neves C, Patterson A, et al. OMERO: Flexible, model-driven data management for experimental biology. Nat Methods 2012;9:245–253.
-
(2012)
Nat Methods
, vol.9
, pp. 245-253
-
-
Allan, C.1
Burel, J.-M.2
Moore, J.3
Blackburn, C.4
Linkert, M.5
Loynton, S.6
MacDonald, D.7
Moore, W.J.8
Neves, C.9
Patterson, A.10
-
83
-
-
33845792555
-
CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
-
Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J, Golland P, Sabatini DM. CellProfiler: Image analysis software for identifying and quantifying cell phenotypes. Genome Biol 2006;7:R100.
-
(2006)
Genome Biol
, vol.7
, pp. R100
-
-
Carpenter, A.E.1
Jones, T.R.2
Lamprecht, M.R.3
Clarke, C.4
Kang, I.H.5
Friman, O.6
Guertin, D.A.7
Chang, J.H.8
Lindquist, R.A.9
Moffat, J.10
Golland, P.11
Sabatini, D.M.12
-
84
-
-
84886768396
-
cellXpress: A fast and user-friendly software platform for profiling cellular phenotypes
-
Laksameethanasan D, Tan RZ, Toh GW, Loo L-H. cellXpress: A fast and user-friendly software platform for profiling cellular phenotypes. BMC Bioinf 2013;14:S4.
-
(2013)
BMC Bioinf
, vol.14
, pp. S4
-
-
Laksameethanasan, D.1
Tan, R.Z.2
Toh, G.W.3
Loo, L.-H.4
-
85
-
-
84872256757
-
Machine learning and its applications to biology
-
Tarca AL, Carey VJ, Chen X, Romero R, Drăghici S. Machine learning and its applications to biology. PLoS Comput Biol 2007;3:e116.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Tarca, A.L.1
Carey, V.J.2
Chen, X.3
Romero, R.4
Drăghici, S.5
-
86
-
-
77953276042
-
Clustering phenotype populations by genome-wide RNAi and multiparametric imaging
-
Fuchs F, Pau G, Kranz D, Sklyar O, Budjan C, Steinbrink S, Horn T, Pedal A, Huber W, Boutros M. Clustering phenotype populations by genome-wide RNAi and multiparametric imaging. Mol Syst Biol 2010;6:370.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 370
-
-
Fuchs, F.1
Pau, G.2
Kranz, D.3
Sklyar, O.4
Budjan, C.5
Steinbrink, S.6
Horn, T.7
Pedal, A.8
Huber, W.9
Boutros, M.10
-
87
-
-
84863203974
-
Unsupervised modeling of cell morphology dynamics for time-lapse microscopy
-
Zhong Q, Busetto AG, Fededa JP, Buhmann JM, Gerlich DW. Unsupervised modeling of cell morphology dynamics for time-lapse microscopy. Nat Methods 2012;9:711–713.
-
(2012)
Nat Methods
, vol.9
, pp. 711-713
-
-
Zhong, Q.1
Busetto, A.G.2
Fededa, J.P.3
Buhmann, J.M.4
Gerlich, D.W.5
-
88
-
-
0036139314
-
A neural network classifier capable of recognizing the patterns of all major subcellular structures in fluorescence microscope images of HeLa cells
-
Boland MV, Murphy RF. A neural network classifier capable of recognizing the patterns of all major subcellular structures in fluorescence microscope images of HeLa cells. Bioinformatics 2001;17:1213–1223.
-
(2001)
Bioinformatics
, vol.17
, pp. 1213-1223
-
-
Boland, M.V.1
Murphy, R.F.2
-
89
-
-
84883467254
-
Determining the subcellular location of new proteins from microscope images using local features
-
Coelho LP, Kangas JD, Naik AW, Osuna-Highley E, Glory-Afshar E, Fuhrman M, Simha R, Berget PB, Jarvik JW, Murphy RF. Determining the subcellular location of new proteins from microscope images using local features. Bioinformatics 2013;29:2343–2349.
-
(2013)
Bioinformatics
, vol.29
, pp. 2343-2349
-
-
Coelho, L.P.1
Kangas, J.D.2
Naik, A.W.3
Osuna-Highley, E.4
Glory-Afshar, E.5
Fuhrman, M.6
Simha, R.7
Berget, P.B.8
Jarvik, J.W.9
Murphy, R.F.10
-
91
-
-
77956339402
-
CellCognition: Time-resolved phenotype annotation in high-throughput live cell imaging
-
Held M, Schmitz MHA, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, Gerlich DW. CellCognition: Time-resolved phenotype annotation in high-throughput live cell imaging. Nat Methods 2010;7:747–754.
-
(2010)
Nat Methods
, vol.7
, pp. 747-754
-
-
Held, M.1
Schmitz, M.H.A.2
Fischer, B.3
Walter, T.4
Neumann, B.5
Olma, M.H.6
Peter, M.7
Ellenberg, J.8
Gerlich, D.W.9
-
94
-
-
48349111792
-
Wndchrm—An open source utility for biological image analysis
-
Shamir L, Orlov N, Eckley DM, Macura T, Johnston J, Goldberg IG. Wndchrm—An open source utility for biological image analysis. Source Code Biol. Med 2008;3:13.
-
(2008)
Source Code Biol. Med
, vol.3
, pp. 13
-
-
Shamir, L.1
Orlov, N.2
Eckley, D.M.3
Macura, T.4
Johnston, J.5
Goldberg, I.G.6
-
96
-
-
33745561205
-
An introduction to variable and feature selection
-
Guyon I, Elisseeff A. An introduction to variable and feature selection. J Mach Learn Res 2003;3:1157–1182.
-
(2003)
J Mach Learn Res
, vol.3
, pp. 1157-1182
-
-
Guyon, I.1
Elisseeff, A.2
-
97
-
-
0242628975
-
Feature reduction for improved recognition of subcellular location patterns in fluorescence microscope images
-
Huang K, Velliste M, Murphy RF. Feature reduction for improved recognition of subcellular location patterns in fluorescence microscope images. Proc SPIE 2003;4962:307–318.
-
(2003)
Proc SPIE
, vol.4962
, pp. 307-318
-
-
Huang, K.1
Velliste, M.2
Murphy, R.F.3
-
99
-
-
0036161259
-
Gene selection for cancer classification using support vector machines
-
Guyon I, Weston J, Barnhill S, Vapnik V. Gene selection for cancer classification using support vector machines. Mach Learn 2002;46:389–422.
-
(2002)
Mach Learn
, vol.46
, pp. 389-422
-
-
Guyon, I.1
Weston, J.2
Barnhill, S.3
Vapnik, V.4
-
101
-
-
0024895461
-
A note on genetic algorithms for large-scale feature selection
-
Siedlecki W, Sklansky J. A note on genetic algorithms for large-scale feature selection. Pattern Recognit Lett 1989;10:335–347.
-
(1989)
Pattern Recognit Lett
, vol.10
, pp. 335-347
-
-
Siedlecki, W.1
Sklansky, J.2
-
102
-
-
0001710505
-
Analysis of a complex of statistical variables into principal components
-
Hotelling H. Analysis of a complex of statistical variables into principal components. J Educ Psychol 1933;24:417–441.
-
(1933)
J Educ Psychol
, vol.24
, pp. 417-441
-
-
Hotelling, H.1
-
103
-
-
33846515112
-
Partial least squares: A versatile tool for the analysis of high-dimensional genomic data
-
Boulesteix A-L, Strimmer K. Partial least squares: A versatile tool for the analysis of high-dimensional genomic data. Brief Bioinform 2007;8:32–44.
-
(2007)
Brief Bioinform
, vol.8
, pp. 32-44
-
-
Boulesteix, A.-L.1
Strimmer, K.2
-
104
-
-
84890056425
-
High quality machine-robust image features: Identification in nonsmall cell lung cancer computed tomography images
-
Hunter LA, Krafft S, Stingo F, Choi H, Martel MK, Kry SF, Court LE. High quality machine-robust image features: Identification in nonsmall cell lung cancer computed tomography images. Med Phys 2013;40:121916.
-
(2013)
Med Phys
, vol.40
, pp. 121916
-
-
Hunter, L.A.1
Krafft, S.2
Stingo, F.3
Choi, H.4
Martel, M.K.5
Kry, S.F.6
Court, L.E.7
-
105
-
-
84938850455
-
Radiomic feature clusters and prognostic signatures specific for lung and head & neck cancer
-
Parmar C, Leijenaar RTH, Grossmann P, Rios Velazquez E, Bussink J, Rietveld D, Rietbergen MM, Haibe-Kains B, Lambin P, Aerts HJWL. Radiomic feature clusters and prognostic signatures specific for lung and head & neck cancer. Sci Rep 2015;5:11044.
-
(2015)
Sci Rep
, vol.5
, pp. 11044
-
-
Parmar, C.1
Leijenaar, R.T.H.2
Grossmann, P.3
Rios Velazquez, E.4
Bussink, J.5
Rietveld, D.6
Rietbergen, M.M.7
Haibe-Kains, B.8
Lambin, P.9
Aerts, H.J.W.L.10
-
106
-
-
84950351930
-
Multidimensional scaling: I. Theory and method
-
Torgerson WS. Multidimensional scaling: I. Theory and method. Psychometrika 1952;17:401–419.
-
(1952)
Psychometrika
, vol.17
, pp. 401-419
-
-
Torgerson, W.S.1
-
107
-
-
0347243182
-
Nonlinear Component Analysis as a Kernel Eigenvalue Problem
-
Schölkopf B, Smola A, Müller K-R. Nonlinear Component Analysis as a Kernel Eigenvalue Problem. Neural Comput 1998;10:1299–1319.
-
(1998)
Neural Comput
, vol.10
, pp. 1299-1319
-
-
Schölkopf, B.1
Smola, A.2
Müller, K.-R.3
-
108
-
-
33746600649
-
Reducing the dimensionality of data with neural networks
-
Hinton GE, Salakhutdinov RR. Reducing the dimensionality of data with neural networks. Science 2006;313:504–507.
-
(2006)
Science
, vol.313
, pp. 504-507
-
-
Hinton, G.E.1
Salakhutdinov, R.R.2
-
109
-
-
56449089103
-
Extracting and composing robust features with denoising autoencoders
-
In, New York, NY, ACM, pp
-
Vincent P, Larochelle H, Bengio Y, Manzagol P-A. Extracting and composing robust features with denoising autoencoders. In: Proceedings of 25th International Conference on Machine Learning ICML'08. New York, NY: ACM; 2008. pp 1096–1103.
-
(2008)
Proceedings of 25th International Conference on Machine Learning ICML'08
, pp. 1096-1103
-
-
Vincent, P.1
Larochelle, H.2
Bengio, Y.3
Manzagol, P.-A.4
-
111
-
-
70349466529
-
Population context determines cell-to-cell variability in endocytosis and virus infection
-
Snijder B, Sacher R, Rämö P, Damm E-M, Liberali P, Pelkmans L. Population context determines cell-to-cell variability in endocytosis and virus infection. Nature 2009;461:520–523.
-
(2009)
Nature
, vol.461
, pp. 520-523
-
-
Snijder, B.1
Sacher, R.2
Rämö, P.3
Damm, E.-M.4
Liberali, P.5
Pelkmans, L.6
-
112
-
-
79955149044
-
Image-derived, three-dimensional generative models of cellular organization
-
Peng T, Murphy RF. Image-derived, three-dimensional generative models of cellular organization. Cytometry Part A 2011;79A:383–391.
-
(2011)
Cytometry Part A
, vol.79A
, pp. 383-391
-
-
Peng, T.1
Murphy, R.F.2
-
113
-
-
84953790713
-
Improving drug discovery with high-content phenotypic screens by systematic selection of reporter cell lines
-
Kang J, Hsu C-H, Wu Q, Liu S, Coster AD, Posner BA, Altschuler SJ, Wu LF. Improving drug discovery with high-content phenotypic screens by systematic selection of reporter cell lines. Nat Biotechnol 2016;34:70–77.
-
(2016)
Nat Biotechnol
, vol.34
, pp. 70-77
-
-
Kang, J.1
Hsu, C.-H.2
Wu, Q.3
Liu, S.4
Coster, A.D.5
Posner, B.A.6
Altschuler, S.J.7
Wu, L.F.8
-
114
-
-
0035478854
-
Random forests
-
Breiman L. Random forests. Mach. Learn 2001;45:5–32.
-
(2001)
Mach. Learn
, vol.45
, pp. 5-32
-
-
Breiman, L.1
-
115
-
-
66649115648
-
Automated high-dimensional flow cytometric data analysis
-
Pyne S, Hu X, Wang K, Rossin E, Lin T-I, Maier LM, Baecher-Allan C, McLachlan GJ, Tamayo P, Hafler DA, et al. Automated high-dimensional flow cytometric data analysis. Proc Natl Acad Sci U S A 2009;106:8519–8524.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8519-8524
-
-
Pyne, S.1
Hu, X.2
Wang, K.3
Rossin, E.4
Lin, T.-I.5
Maier, L.M.6
Baecher-Allan, C.7
McLachlan, G.J.8
Tamayo, P.9
Hafler, D.A.10
-
116
-
-
80054768631
-
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE
-
Qiu P, Simonds EF, Bendall SC, Gibbs KD Jr, Bruggner RV, Linderman MD, Sachs K, Nolan GP, Plevritis SK. Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nat Biotechnol 2011;29:886–891.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 886-891
-
-
Qiu, P.1
Simonds, E.F.2
Bendall, S.C.3
Gibbs, K.D.4
Bruggner, R.V.5
Linderman, M.D.6
Sachs, K.7
Nolan, G.P.8
Plevritis, S.K.9
-
117
-
-
0037365194
-
Active learning with support vector machines in the drug discovery process
-
Warmuth MK, Liao J, Rätsch G, Mathieson M, Putta S, Lemmen C. Active learning with support vector machines in the drug discovery process. J Chem Inf Comput Sci 2003;43:667–673.
-
(2003)
J Chem Inf Comput Sci
, vol.43
, pp. 667-673
-
-
Warmuth, M.K.1
Liao, J.2
Rätsch, G.3
Mathieson, M.4
Putta, S.5
Lemmen, C.6
-
118
-
-
84961282066
-
Active machine learning-driven experimentation to determine compound effects on protein patterns
-
Naik AW, Kangas JD, Sullivan DP, Murphy RF. Active machine learning-driven experimentation to determine compound effects on protein patterns. eLife 2016;5:e10047.
-
(2016)
eLife
, vol.5
-
-
Naik, A.W.1
Kangas, J.D.2
Sullivan, D.P.3
Murphy, R.F.4
-
119
-
-
85007430104
-
The WEKA data mining software: An update
-
Hall M, Frank E, Holmes G, Pfahringer B, Reutemann P, Witten IH. The WEKA data mining software: An update. SIGKDD Explor Newsl 2009;11:10–18.
-
(2009)
SIGKDD Explor Newsl
, vol.11
, pp. 10-18
-
-
Hall, M.1
Frank, E.2
Holmes, G.3
Pfahringer, B.4
Reutemann, P.5
Witten, I.H.6
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