-
1
-
-
0033189752
-
After sequencing: Quantitative analysis of protein localization
-
Boland, M.V. & Murphy, R.F. After sequencing: Quantitative analysis of protein localization. IEEE Eng. Med. Biol. Mag. 18, 115-119 (1999).
-
(1999)
IEEE Eng. Med. Biol. Mag
, vol.18
, pp. 115-119
-
-
Boland, M.V.1
Murphy, R.F.2
-
2
-
-
33645464806
-
Cellular imaging in drug discovery
-
Lang, P., Yeow, K., Nichols, A. & Scheer, A. Cellular imaging in drug discovery. Nat. Rev. Drug Discov. 5, 343-356 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 343-356
-
-
Lang, P.1
Yeow, K.2
Nichols, A.3
Scheer, A.4
-
3
-
-
0036980851
-
Advances in molecular labeling, high throughput imaging and machine intelligence portend powerful functional cellular biochemistry tools
-
Price, J.H. et al. Advances in molecular labeling, high throughput imaging and machine intelligence portend powerful functional cellular biochemistry tools. J. Cell. Biochem. Suppl. 39, 194-210 (2002).
-
(2002)
J. Cell. Biochem. Suppl
, vol.39
, pp. 194-210
-
-
Price, J.H.1
-
4
-
-
85032752151
-
Informatics challenges of high-throughput microscopy
-
Zhou, X. & Wong, S.T.C. Informatics challenges of high-throughput microscopy. IEEE Signal Process. Mag. 23, 63-72 (2006).
-
(2006)
IEEE Signal Process. Mag
, vol.23
, pp. 63-72
-
-
Zhou, X.1
Wong, S.T.C.2
-
5
-
-
8444223104
-
Multidimensional drug profiling by automated microscopy
-
Perlman, Z.E. et al. Multidimensional drug profiling by automated microscopy. Science 306, 1194-1198 (2004).
-
(2004)
Science
, vol.306
, pp. 1194-1198
-
-
Perlman, Z.E.1
-
6
-
-
21744448078
-
An unbiased cell morphology-based screen for new, biologically active small molecules
-
Tanaka, M. et al. An unbiased cell morphology-based screen for new, biologically active small molecules. PLoS Biol. 3, e128 (2005).
-
(2005)
PLoS Biol
, vol.3
-
-
Tanaka, M.1
-
7
-
-
0036139314
-
A neural network classifier capable of recognizing the patterns of all major subcellular structures in fluorescence microscope images of HeLa cells
-
Boland, M.V. & Murphy, R.F. A neural network classifier capable of recognizing the patterns of all major subcellular structures in fluorescence microscope images of HeLa cells. Bioinformatics 17 1213-1223 (2001).
-
(2001)
Bioinformatics
, vol.17
, pp. 1213-1223
-
-
Boland, M.V.1
Murphy, R.F.2
-
8
-
-
3042565868
-
Automatic identification of subcellular phenotypes on human cell arrays
-
Conrad, C. et al. Automatic identification of subcellular phenotypes on human cell arrays. Genome Res. 14, 1130-1136 (2004).
-
(2004)
Genome Res
, vol.14
, pp. 1130-1136
-
-
Conrad, C.1
-
9
-
-
33646057010
-
High-throughput RNAi screening by time-lapse imaging of live human cells
-
Neumann, B. et al. High-throughput RNAi screening by time-lapse imaging of live human cells. Nat. Methods 3, 385-390 (2006).
-
(2006)
Nat. Methods
, vol.3
, pp. 385-390
-
-
Neumann, B.1
-
10
-
-
30044445643
-
High-dimensional and large-scale phenotyping of yeast mutants
-
Ohya, Y. et al. High-dimensional and large-scale phenotyping of yeast mutants. Proc. Natl. Acad. Sci. USA 102, 19015-19020 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 19015-19020
-
-
Ohya, Y.1
-
11
-
-
7044227922
-
Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader
-
Gasparri, F., Mariani, M., Sola, F. & Galvani, A. Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader. J. Biomol. Screen. 9 232-243 (2004).
-
(2004)
J. Biomol. Screen
, vol.9
, pp. 232-243
-
-
Gasparri, F.1
Mariani, M.2
Sola, F.3
Galvani, A.4
-
12
-
-
29244462317
-
Systems cell biology knowledge created from high content screening
-
Giuliano, K.A. et al. Systems cell biology knowledge created from high content screening. Assay Drug Dev. Technol. 3, 501-514 (2005).
-
(2005)
Assay Drug Dev. Technol
, vol.3
, pp. 501-514
-
-
Giuliano, K.A.1
-
14
-
-
0003922190
-
-
2nd edn, John Wiley & Sons, New York
-
Duda, R.O., Hart, P.E. & Stork, D.G. Pattern Classification 2nd edn. (John Wiley & Sons, New York, 2001).
-
(2001)
Pattern Classification
-
-
Duda, R.O.1
Hart, P.E.2
Stork, D.G.3
-
15
-
-
0036161259
-
Gene selection for cancer classification using support vector machines
-
Guyon, I., Weston, J., Barnhill, S. & Vapnik, V. Gene selection for cancer classification using support vector machines. Mach. Learn. 46, 389-422 (2002).
-
(2002)
Mach. Learn
, vol.46
, pp. 389-422
-
-
Guyon, I.1
Weston, J.2
Barnhill, S.3
Vapnik, V.4
-
16
-
-
0018466704
-
Statistical and structural approaches to texture
-
Haralick, R.M. Statistical and structural approaches to texture. Proc. IEEE 67, 786-804 (1979).
-
(1979)
Proc. IEEE
, vol.67
, pp. 786-804
-
-
Haralick, R.M.1
-
18
-
-
1542702936
-
A simple technique for reducing edge effect in cell-based Assays
-
Lundholt, B.K., Scudder, K.M. & Pagliaro, L. A simple technique for reducing edge effect in cell-based Assays. J. Biomol. Screen. 8 566-570 (2003).
-
(2003)
J. Biomol. Screen
, vol.8
, pp. 566-570
-
-
Lundholt, B.K.1
Scudder, K.M.2
Pagliaro, L.3
-
19
-
-
32344448950
-
Statistical practice in high-throughput screening data analysis
-
Malo, N., Hanley, J.A., Cerquozzi, S., Pelletier, J. & Nadon, R. Statistical practice in high-throughput screening data analysis. Nat. Biotechnol. 24, 167-175 (2006).
-
(2006)
Nat. Biotechnol
, vol.24
, pp. 167-175
-
-
Malo, N.1
Hanley, J.A.2
Cerquozzi, S.3
Pelletier, J.4
Nadon, R.5
-
20
-
-
0003684449
-
-
Springer-Verlag, New York
-
Hastie, T., Tibshirani, R. & Friedman, J. The Elements of Statistical Learning: Data Mining, Inference, and Prediction. (Springer-Verlag, New York, 2001).
-
(2001)
The Elements of Statistical Learning: Data Mining, Inference, and Prediction
-
-
Hastie, T.1
Tibshirani, R.2
Friedman, J.3
-
21
-
-
0033600733
-
The mode of action of taxol: Apoptosis at low concentration and necrosis at high concentration
-
Yeung, T.K., Germond, C., Chen, X. & Wang, Z. The mode of action of taxol: Apoptosis at low concentration and necrosis at high concentration. Biochem. Biophys. Res. Commun. 263, 398-404 (1999).
-
(1999)
Biochem. Biophys. Res. Commun
, vol.263
, pp. 398-404
-
-
Yeung, T.K.1
Germond, C.2
Chen, X.3
Wang, Z.4
-
22
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo, C.B. & Jones, P.A. Epigenetic therapy of cancer: Past, present and future. Nat. Rev. Drug Discov. 5, 37-50 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
23
-
-
12344253075
-
High-content screening and profiling of drug activity in an automated centrosome-duplication assay
-
Perlman, Z.E., Mitchison, T.J. & Mayer, T.U. High-content screening and profiling of drug activity in an automated centrosome-duplication assay. ChemBioChem 6, 145-151 (2005).
-
(2005)
ChemBioChem
, vol.6
, pp. 145-151
-
-
Perlman, Z.E.1
Mitchison, T.J.2
Mayer, T.U.3
-
24
-
-
0029049468
-
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action
-
Bollag, D.M. et al. Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action. Cancer Res. 55, 2325-2333 (1995).
-
(1995)
Cancer Res
, vol.55
, pp. 2325-2333
-
-
Bollag, D.M.1
-
25
-
-
22244469477
-
Kinetic suppression of microtubule dynamic instability by griseofulvin: Implications for its possible use in the treatment of cancer
-
Panda, D., Rathinasamy, K., Santra, M.K. & Wilson, L. Kinetic suppression of microtubule dynamic instability by griseofulvin: implications for its possible use in the treatment of cancer. Proc. Natl. Acad. Sci. USA 102, 9878-9883 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9878-9883
-
-
Panda, D.1
Rathinasamy, K.2
Santra, M.K.3
Wilson, L.4
-
26
-
-
2942616604
-
Complex phenotypic assays in high-throughput screening
-
Clemons, P.A. Complex phenotypic assays in high-throughput screening. Curr. Opin. Chem. Biol. 8, 334-338 (2004).
-
(2004)
Curr. Opin. Chem. Biol
, vol.8
, pp. 334-338
-
-
Clemons, P.A.1
-
27
-
-
0032832775
-
Drug screening-beyond the bottleneck
-
Dove, A. Drug screening-beyond the bottleneck. Nat. Biotechnol. 17, 859-863 (1999).
-
(1999)
Nat. Biotechnol
, vol.17
, pp. 859-863
-
-
Dove, A.1
-
28
-
-
33645832853
-
-
Maciag, K. et al. Systems-level analyses identify extensive coupling among gene expression machines. Mol. Syst. Biol. [online] 2, 0003 (2006) (doi:10.1038/msb4100045).
-
Maciag, K. et al. Systems-level analyses identify extensive coupling among gene expression machines. Mol. Syst. Biol. [online] 2, 0003 (2006) (doi:10.1038/msb4100045).
-
-
-
-
29
-
-
0020083498
-
The meaning and use of the area under a receiver operating characteristic (ROC) curve
-
Hanley, J.A. & McNeil, B.J. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 143 29-36 (1982).
-
(1982)
Radiology
, vol.143
, pp. 29-36
-
-
Hanley, J.A.1
McNeil, B.J.2
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