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Volumn 31, Issue 6, 2017, Pages 1053-1057

Effects of pioglitazone on the incidence of dementia in patients with diabetes

Author keywords

Dementia; Diabetes mellitus; National health insurance research database; Peroxisome proliferator activated receptor gamma; Pioglitazone

Indexed keywords

PIOGLITAZONE; 2,4 THIAZOLIDINEDIONE DERIVATIVE;

EID: 85013057058     PISSN: 10568727     EISSN: 1873460X     Source Type: Journal    
DOI: 10.1016/j.jdiacomp.2017.01.006     Document Type: Article
Times cited : (42)

References (32)
  • 1
    • 77957940731 scopus 로고    scopus 로고
    • Diabetes, Alzheimer disease, and vascular dementia: A population-based neuropathologic study
    • Ahtiluoto, S., Polvikoski, T., Peltonen, M., Solomon, A., Tuomilehto, J., Winblad, B., Kivipelto, M., Diabetes, Alzheimer disease, and vascular dementia: A population-based neuropathologic study. Neurology 75:13 (2010), 1195–1202, 10.1212/WNL.0b013e3181f4d7f8.
    • (2010) Neurology , vol.75 , Issue.13 , pp. 1195-1202
    • Ahtiluoto, S.1    Polvikoski, T.2    Peltonen, M.3    Solomon, A.4    Tuomilehto, J.5    Winblad, B.6    Kivipelto, M.7
  • 2
    • 42049101837 scopus 로고    scopus 로고
    • Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling
    • Beyer, A.M., Baumbach, G.L., Halabi, C.M., Modrick, M.L., Lynch, C.M., Gerhold, T.D., Faraci, F.M., Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension 51:4 (2008), 867–871, 10.1161/HYPERTENSIONAHA.107.103648.
    • (2008) Hypertension , vol.51 , Issue.4 , pp. 867-871
    • Beyer, A.M.1    Baumbach, G.L.2    Halabi, C.M.3    Modrick, M.L.4    Lynch, C.M.5    Gerhold, T.D.6    Faraci, F.M.7
  • 4
    • 77954546616 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, dyslipidemia, and Alzheimer's disease
    • Carlsson, C.M., Type 2 diabetes mellitus, dyslipidemia, and Alzheimer's disease. Journal of Alzheimer's Disease 20:3 (2010), 711–722, 10.3233/JAD-2010-100012.
    • (2010) Journal of Alzheimer's Disease , vol.20 , Issue.3 , pp. 711-722
    • Carlsson, C.M.1
  • 5
    • 84865861369 scopus 로고    scopus 로고
    • Newly diagnosed type 2 diabetes and risk of dementia: A population-based 7-year follow-up study in Taiwan
    • Cheng, P.Y., Sy, H.N., Wu, S.L., Wang, W.F., Chen, Y.Y., Newly diagnosed type 2 diabetes and risk of dementia: A population-based 7-year follow-up study in Taiwan. Journal of Diabetes and its Complications 26:5 (2012), 382–387, 10.1016/j.jdiacomp.2012.06.003.
    • (2012) Journal of Diabetes and its Complications , vol.26 , Issue.5 , pp. 382-387
    • Cheng, P.Y.1    Sy, H.N.2    Wu, S.L.3    Wang, W.F.4    Chen, Y.Y.5
  • 6
    • 0034651101 scopus 로고    scopus 로고
    • Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
    • Combs, C.K., Johnson, D.E., Karlo, J.C., Cannady, S.B., Landreth, G.E., Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. The Journal of Neuroscience 20:2 (2000), 558–567.
    • (2000) The Journal of Neuroscience , vol.20 , Issue.2 , pp. 558-567
    • Combs, C.K.1    Johnson, D.E.2    Karlo, J.C.3    Cannady, S.B.4    Landreth, G.E.5
  • 7
    • 34147173277 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment
    • Craft, S., Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment. Current Alzheimer Research 4:2 (2007), 147–152.
    • (2007) Current Alzheimer Research , vol.4 , Issue.2 , pp. 147-152
    • Craft, S.1
  • 8
    • 62449142597 scopus 로고    scopus 로고
    • The role of metabolic disorders in Alzheimer disease and vascular dementia: Two roads converged
    • Craft, S., The role of metabolic disorders in Alzheimer disease and vascular dementia: Two roads converged. Archives of Neurology 66:3 (2009), 300–305, 10.1001/archneurol.2009.27.
    • (2009) Archives of Neurology , vol.66 , Issue.3 , pp. 300-305
    • Craft, S.1
  • 9
    • 84856496197 scopus 로고    scopus 로고
    • Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease
    • de la Monte, S.M., Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. Current Alzheimer Research 9:1 (2012), 35–66.
    • (2012) Current Alzheimer Research , vol.9 , Issue.1 , pp. 35-66
    • de la Monte, S.M.1
  • 10
    • 84947046996 scopus 로고    scopus 로고
    • Vascular dysfunction in the pathogenesis of Alzheimer's disease—A review of endothelium-mediated mechanisms and ensuing vicious circles
    • Di Marco, L.Y., Venneri, A., Farkas, E., Evans, P.C., Marzo, A., Frangi, A.F., Vascular dysfunction in the pathogenesis of Alzheimer's disease—A review of endothelium-mediated mechanisms and ensuing vicious circles. Neurobiology of Disease 82 (2015), 593–606, 10.1016/j.nbd.2015.08.014.
    • (2015) Neurobiology of Disease , vol.82 , pp. 593-606
    • Di Marco, L.Y.1    Venneri, A.2    Farkas, E.3    Evans, P.C.4    Marzo, A.5    Frangi, A.F.6
  • 11
    • 84937733175 scopus 로고    scopus 로고
    • Effect of pioglitazone medication on the incidence of dementia
    • Heneka, M.T., Fink, A., Doblhammer, G., Effect of pioglitazone medication on the incidence of dementia. Annals of Neurology 78:2 (2015), 284–294, 10.1002/ana.24439.
    • (2015) Annals of Neurology , vol.78 , Issue.2 , pp. 284-294
    • Heneka, M.T.1    Fink, A.2    Doblhammer, G.3
  • 12
    • 0034666289 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo
    • Heneka, M.T., Klockgether, T., Feinstein, D.L., Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. The Journal of Neuroscience 20:18 (2000), 6862–6867.
    • (2000) The Journal of Neuroscience , vol.20 , Issue.18 , pp. 6862-6867
    • Heneka, M.T.1    Klockgether, T.2    Feinstein, D.L.3
  • 13
    • 20444499367 scopus 로고    scopus 로고
    • Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice
    • Heneka, M.T., Sastre, M., Dumitrescu-Ozimek, L., Hanke, A., Dewachter, I., Kuiperi, C., Landreth, G.E., Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain 128:Pt 6 (2005), 1442–1453, 10.1093/brain/awh452.
    • (2005) Brain , vol.128 , pp. 1442-1453
    • Heneka, M.T.1    Sastre, M.2    Dumitrescu-Ozimek, L.3    Hanke, A.4    Dewachter, I.5    Kuiperi, C.6    Landreth, G.E.7
  • 14
    • 79956277464 scopus 로고    scopus 로고
    • Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin
    • Hsu, C.C., Wahlqvist, M.L., Lee, M.S., Tsai, H.N., Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin. Journal of Alzheimer's Disease 24:3 (2011), 485–493, 10.3233/JAD-2011-101524.
    • (2011) Journal of Alzheimer's Disease , vol.24 , Issue.3 , pp. 485-493
    • Hsu, C.C.1    Wahlqvist, M.L.2    Lee, M.S.3    Tsai, H.N.4
  • 15
    • 84861233877 scopus 로고    scopus 로고
    • Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case–control study
    • Imfeld, P., Bodmer, M., Jick, S.S., Meier, C.R., Metformin, other antidiabetic drugs, and risk of Alzheimer's disease: a population-based case–control study. Journal of the American Geriatrics Society 60:5 (2012), 916–921, 10.1111/j.1532-5415.2012.03916.x.
    • (2012) Journal of the American Geriatrics Society , vol.60 , Issue.5 , pp. 916-921
    • Imfeld, P.1    Bodmer, M.2    Jick, S.S.3    Meier, C.R.4
  • 16
    • 20444398490 scopus 로고    scopus 로고
    • Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation
    • Luna-Medina, R., Cortes-Canteli, M., Alonso, M., Santos, A., Martinez, A., Perez-Castillo, A., Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation. The Journal of Biological Chemistry 280:22 (2005), 21453–21462, 10.1074/jbc.M414390200.
    • (2005) The Journal of Biological Chemistry , vol.280 , Issue.22 , pp. 21453-21462
    • Luna-Medina, R.1    Cortes-Canteli, M.2    Alonso, M.3    Santos, A.4    Martinez, A.5    Perez-Castillo, A.6
  • 18
    • 84902239478 scopus 로고    scopus 로고
    • Long-term metformin usage and cognitive function among older adults with diabetes
    • Ng, T.P., Feng, L., Yap, K.B., Lee, T.S., Tan, C.H., Winblad, B., Long-term metformin usage and cognitive function among older adults with diabetes. Journal of Alzheimer's Disease 41:1 (2014), 61–68, 10.3233/JAD-131901.
    • (2014) Journal of Alzheimer's Disease , vol.41 , Issue.1 , pp. 61-68
    • Ng, T.P.1    Feng, L.2    Yap, K.B.3    Lee, T.S.4    Tan, C.H.5    Winblad, B.6
  • 19
    • 55249125525 scopus 로고    scopus 로고
    • Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist
    • Nicolakakis, N., Aboulkassim, T., Ongali, B., Lecrux, C., Fernandes, P., Rosa-Neto, P., Hamel, E., Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist. The Journal of Neuroscience 28:37 (2008), 9287–9296, 10.1523/JNEUROSCI.3348-08.2008.
    • (2008) The Journal of Neuroscience , vol.28 , Issue.37 , pp. 9287-9296
    • Nicolakakis, N.1    Aboulkassim, T.2    Ongali, B.3    Lecrux, C.4    Fernandes, P.5    Rosa-Neto, P.6    Hamel, E.7
  • 20
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators
    • Pasceri, V., Wu, H.D., Willerson, J.T., Yeh, E.T., Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation 101:3 (2000), 235–238.
    • (2000) Circulation , vol.101 , Issue.3 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3    Yeh, E.T.4
  • 21
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
    • Peila, R., Rodriguez, B.L., Launer, L.J., Honolulu-Asia Aging Study, Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes 51:4 (2002), 1256–1262.
    • (2002) Diabetes , vol.51 , Issue.4 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3    Honolulu-Asia Aging Study4
  • 22
    • 84947243229 scopus 로고    scopus 로고
    • Therapeutic actions of the thiazolidinediones in Alzheimer's disease
    • Perez, M.J., Quintanilla, R.A., Therapeutic actions of the thiazolidinediones in Alzheimer's disease. PPAR Research, 2015, 2015, 957248, 10.1155/2015/957248.
    • (2015) PPAR Research , vol.2015 , pp. 957248
    • Perez, M.J.1    Quintanilla, R.A.2
  • 23
    • 84872109456 scopus 로고    scopus 로고
    • The global prevalence of dementia: A systematic review and metaanalysis
    • Prince, M., Bryce, R., Albanese, E., Wimo, A., Ribeiro, W., Ferri, C.P., The global prevalence of dementia: A systematic review and metaanalysis. Alzheimers Dement 9:1 (2013), 63–75.e2, 10.1016/j.jalz.2012.11.007.
    • (2013) Alzheimers Dement , vol.9 , Issue.1 , pp. 63-75.e2
    • Prince, M.1    Bryce, R.2    Albanese, E.3    Wimo, A.4    Ribeiro, W.5    Ferri, C.P.6
  • 24
    • 0242609178 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase
    • Sastre, M., Dewachter, I., Landreth, G.E., Willson, T.M., Klockgether, T., van Leuven, F., Heneka, M.T., Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. The Journal of Neuroscience 23:30 (2003), 9796–9804.
    • (2003) The Journal of Neuroscience , vol.23 , Issue.30 , pp. 9796-9804
    • Sastre, M.1    Dewachter, I.2    Landreth, G.E.3    Willson, T.M.4    Klockgether, T.5    van Leuven, F.6    Heneka, M.T.7
  • 26
    • 80054812684 scopus 로고    scopus 로고
    • Behavioral and biochemical investigations to explore pharmacological potential of PPAR-gamma agonists in vascular dementia of diabetic rats
    • Sharma, B., Singh, N., Behavioral and biochemical investigations to explore pharmacological potential of PPAR-gamma agonists in vascular dementia of diabetic rats. Pharmacology, Biochemistry, and Behavior 100:2 (2011), 320–329, 10.1016/j.pbb.2011.08.020.
    • (2011) Pharmacology, Biochemistry, and Behavior , vol.100 , Issue.2 , pp. 320-329
    • Sharma, B.1    Singh, N.2
  • 27
    • 69249215302 scopus 로고    scopus 로고
    • Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes
    • Tsuchiya, K., Akaza, I., Yoshimoto, T., Hirata, Y., Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes. Endocrine Journal 56:5 (2009), 691–698.
    • (2009) Endocrine Journal , vol.56 , Issue.5 , pp. 691-698
    • Tsuchiya, K.1    Akaza, I.2    Yoshimoto, T.3    Hirata, Y.4
  • 28
    • 2942670612 scopus 로고    scopus 로고
    • PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: Role of diacylglycerol kinase
    • Verrier, E., Wang, L., Wadham, C., Albanese, N., Hahn, C., Gamble, J.R., Xia, P., PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: Role of diacylglycerol kinase. Circulation Research 94:11 (2004), 1515–1522, 10.1161/01.RES.0000130527.92537.06.
    • (2004) Circulation Research , vol.94 , Issue.11 , pp. 1515-1522
    • Verrier, E.1    Wang, L.2    Wadham, C.3    Albanese, N.4    Hahn, C.5    Gamble, J.R.6    Xia, P.7
  • 29
    • 0037221379 scopus 로고    scopus 로고
    • The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications for treatment
    • Watson, G.S., Craft, S., The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications for treatment. CNS Drugs 17:1 (2003), 27–45.
    • (2003) CNS Drugs , vol.17 , Issue.1 , pp. 27-45
    • Watson, G.S.1    Craft, S.2
  • 31
    • 5344237420 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study
    • Xu, W.L., Qiu, C.X., Wahlin, A., Winblad, B., Fratiglioni, L., Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study. Neurology 63:7 (2004), 1181–1186.
    • (2004) Neurology , vol.63 , Issue.7 , pp. 1181-1186
    • Xu, W.L.1    Qiu, C.X.2    Wahlin, A.3    Winblad, B.4    Fratiglioni, L.5
  • 32
    • 84870226700 scopus 로고    scopus 로고
    • PPARgamma/RXRalpha-induced and CD36-mediated microglial amyloid-beta phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice
    • Yamanaka, M., Ishikawa, T., Griep, A., Axt, D., Kummer, M.P., Heneka, M.T., PPARgamma/RXRalpha-induced and CD36-mediated microglial amyloid-beta phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. The Journal of Neuroscience 32:48 (2012), 17321–17331, 10.1523/JNEUROSCI.1569-12.2012.
    • (2012) The Journal of Neuroscience , vol.32 , Issue.48 , pp. 17321-17331
    • Yamanaka, M.1    Ishikawa, T.2    Griep, A.3    Axt, D.4    Kummer, M.P.5    Heneka, M.T.6


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