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Volumn 100, Issue 2, 2011, Pages 320-329

Behavioral and biochemical investigations to explore pharmacological potential of PPAR-gamma agonists in vascular dementia of diabetic rats

Author keywords

Alzheimer's disease; Donepezil; Morris water maze; Oxidative stress; Pioglitazone; Vascular endothelial dysfunction

Indexed keywords

ACETYLCHOLINESTERASE; DONEPEZIL; GLUCOSE; GLUTATHIONE; NITRATE; NITRITE; PIOGLITAZONE; ROSIGLITAZONE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 80054812684     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2011.08.020     Document Type: Article
Times cited : (47)

References (85)
  • 1
    • 77951249178 scopus 로고    scopus 로고
    • Dementia and insulin resistance in patients with diabetes mellitus
    • A. Araki Dementia and insulin resistance in patients with diabetes mellitus Nippon Rinsho 68 3 2010 569 574
    • (2010) Nippon Rinsho , vol.68 , Issue.3 , pp. 569-574
    • Araki, A.1
  • 2
    • 77955346280 scopus 로고    scopus 로고
    • Nuclear receptors of the peroxisome proliferator-activated (PPAR) family in gestational diabetes - From animal models to clinical trials
    • P. Arck, B. Toth, A. Pestka, and U. Jeschke Nuclear receptors of the peroxisome proliferator-activated (PPAR) family in gestational diabetes - from animal models to clinical trials Biol Reprod 83 2010 168 176
    • (2010) Biol Reprod , vol.83 , pp. 168-176
    • Arck, P.1    Toth, B.2    Pestka, A.3    Jeschke, U.4
  • 3
    • 77952543578 scopus 로고    scopus 로고
    • PPAR-gamma agonists and their role in type 2 diabetes mellitus management
    • V. Bermudez, F. Finol, N. Parra, M. Parra, A. Pérez, and L. Peñaranda PPAR-gamma agonists and their role in type 2 diabetes mellitus management Am J Ther 17 2010 274 283
    • (2010) Am J Ther , vol.17 , pp. 274-283
    • Bermudez, V.1    Finol, F.2    Parra, N.3    Parra, M.4    Pérez, A.5    Peñaranda, L.6
  • 7
    • 0014572551 scopus 로고
    • Streptozotocin diabetes in the mouse and guinea pig
    • G. Brosky, and J. Logothetopoulos Streptozotocin diabetes in the mouse and guinea pig Diabetes 18 9 1969 606 611
    • (1969) Diabetes , vol.18 , Issue.9 , pp. 606-611
    • Brosky, G.1    Logothetopoulos, J.2
  • 8
    • 77956894853 scopus 로고    scopus 로고
    • Memantine is a useful drug to prevent the spatial and non-spatial memory deficits induced by methamphetamine in rats
    • J. Camarasa, T. Rodrigo, D. Pubill, and E. Escubedo Memantine is a useful drug to prevent the spatial and non-spatial memory deficits induced by methamphetamine in rats Pharmacol Res 62 5 2010 450 456
    • (2010) Pharmacol Res , vol.62 , Issue.5 , pp. 450-456
    • Camarasa, J.1    Rodrigo, T.2    Pubill, D.3    Escubedo, E.4
  • 10
    • 77956544347 scopus 로고    scopus 로고
    • Sesamol suppresses neuro-inflammatory cascade in experimental model of diabetic neuropathy
    • K. Chopra, V. Tiwari, V. Arora, and A. Kuhad Sesamol suppresses neuro-inflammatory cascade in experimental model of diabetic neuropathy J Pain 11 10 2010 950 957
    • (2010) J Pain , vol.11 , Issue.10 , pp. 950-957
    • Chopra, K.1    Tiwari, V.2    Arora, V.3    Kuhad, A.4
  • 11
    • 77953172665 scopus 로고    scopus 로고
    • PPAR{gamma} activation prevents hypertensive remodeling of cerebral arteries and improves vascular function in female rats
    • M.J. Cipolla, N. Bishop, R.S. Vinke, and J.A. Godfrey PPAR{gamma} activation prevents hypertensive remodeling of cerebral arteries and improves vascular function in female rats Stroke 41 2010 1266 1270
    • (2010) Stroke , vol.41 , pp. 1266-1270
    • Cipolla, M.J.1    Bishop, N.2    Vinke, R.S.3    Godfrey, J.A.4
  • 12
    • 47849112648 scopus 로고    scopus 로고
    • Alzheimer's disease prevalence can be lowered with non-invasive testing
    • J.C. de la Torre Alzheimer's disease prevalence can be lowered with non-invasive testing J Alzheimers Dis 14 3 2008 353 359 (Pubitemid 352040048)
    • (2008) Journal of Alzheimer's Disease , vol.14 , Issue.3 , pp. 353-359
    • De La Torre, J.C.1
  • 13
    • 39449102532 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ-mediated effects in the vasculature
    • DOI 10.1161/CIRCRESAHA.107.164384, PII 0000301220080215000007
    • S.Z. Duan, M.G. Usher, and R.M. Mortensen Peroxisome proliferator- activated receptor-gammamediated effects in the vasculature Circ Res 102 2008 283 294 (Pubitemid 351271648)
    • (2008) Circulation Research , vol.102 , Issue.3 , pp. 283-294
    • Duan, S.Z.1    Usher, M.G.2    Mortensen, R.M.3
  • 14
    • 33644811612 scopus 로고
    • A new and rapid colorimeteric determination of acetylcholinesterase activity
    • G.L. Ellman, D.K. Courtney, V. Andres, and R.M. Feathstone A new and rapid colorimeteric determination of acetylcholinesterase activity Biochem Pharmacol 7 1961 88 95
    • (1961) Biochem Pharmacol , vol.7 , pp. 88-95
    • Ellman, G.L.1    Courtney, D.K.2    Andres, V.3    Feathstone, R.M.4
  • 15
    • 79951944520 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors-gamma PPAR-gamma) activation confers functional neuroprotection in global ischemia
    • Z. Fatehi-Hassanabad, and R.A. Tasker Peroxisome proliferator-activated receptors-gamma PPAR-gamma) activation confers functional neuroprotection in global ischemia Neurotox Res 19 3 2011 462 471
    • (2011) Neurotox Res , vol.19 , Issue.3 , pp. 462-471
    • Fatehi-Hassanabad, Z.1    Tasker, R.A.2
  • 17
    • 77954383974 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptors gamma and peroxisome-proliferator-activated receptors beta/delta and the regulation of interleukin 1 receptors antagonist expression by pioglitazone in ischemic brain
    • T. Glatz, I. Stock, M. Nguyen-Ngoc, P. Gohlke, T. Herdegen, and J. Culman Peroxisome-proliferator-activated receptors gamma and peroxisome-proliferator- activated receptors beta/delta and the regulation of interleukin 1 receptors antagonist expression by pioglitazone in ischemic brain J Hypertens 28 2010 1488 1497
    • (2010) J Hypertens , vol.28 , pp. 1488-1497
    • Glatz, T.1    Stock, I.2    Nguyen-Ngoc, M.3    Gohlke, P.4    Herdegen, T.5    Culman, J.6
  • 18
    • 75149116312 scopus 로고    scopus 로고
    • Treatment with the PPARgamma agonist rosiglitazone downregulates interleukin-1 receptors antagonist in individuals with metabolic syndrome
    • B. Halvorsen, E. Heggen, T. Ueland, C. Smith, W.J. Sandberg, and J.K. Damås Treatment with the PPARgamma agonist rosiglitazone downregulates interleukin-1 receptors antagonist in individuals with metabolic syndrome Eur J Endocrinol 162 2010 267 273
    • (2010) Eur J Endocrinol , vol.162 , pp. 267-273
    • Halvorsen, B.1    Heggen, E.2    Ueland, T.3    Smith, C.4    Sandberg, W.J.5    Damås, J.K.6
  • 19
    • 77949879781 scopus 로고    scopus 로고
    • Alzheimer's disease
    • H. Hanyu, and T. Sato Alzheimer's disease Nippon Rinsho 68 2010 330 334
    • (2010) Nippon Rinsho , vol.68 , pp. 330-334
    • Hanyu, H.1    Sato, T.2
  • 21
    • 77953202134 scopus 로고    scopus 로고
    • Cardiac-specific IGF-1 receptor transgenic expression protects against cardiac fibrosis and diastolic dysfunction in a mouse model of diabetic cardiomyopathy
    • K. Huynh, J.R. McMullen, T.L. Julius, J.W. Tan, J.E. Love, and N. Cemerlang Cardiac-specific IGF-1 receptor transgenic expression protects against cardiac fibrosis and diastolic dysfunction in a mouse model of diabetic cardiomyopathy Diabetes 59 6 2010 1512 1520
    • (2010) Diabetes , vol.59 , Issue.6 , pp. 1512-1520
    • Huynh, K.1    McMullen, J.R.2    Julius, T.L.3    Tan, J.W.4    Love, J.E.5    Cemerlang, N.6
  • 22
    • 58449107369 scopus 로고    scopus 로고
    • Endothelial dysfunction: A potential therapeutic target for geriatric depression and brain amyloid deposition in Alzheimer's disease?
    • E. Isingrini, T. Desmidt, C. Belzung, and V. Camus Endothelial dysfunction: a potential therapeutic target for geriatric depression and brain amyloid deposition in Alzheimer's disease? Curr Opin Investig Drugs 10 1 2009 46 55
    • (2009) Curr Opin Investig Drugs , vol.10 , Issue.1 , pp. 46-55
    • Isingrini, E.1    Desmidt, T.2    Belzung, C.3    Camus, V.4
  • 24
    • 65249177213 scopus 로고    scopus 로고
    • Ameliorative potential of rosiglitazone in tibial and sural nerve transection-induced painful neuropathy in rats
    • V. Jain, A.S. Jaggi, and N. Singh Ameliorative potential of rosiglitazone in tibial and sural nerve transection-induced painful neuropathy in rats Pharmacol Res 59 2009 385 392
    • (2009) Pharmacol Res , vol.59 , pp. 385-392
    • Jain, V.1    Jaggi, A.S.2    Singh, N.3
  • 25
    • 70349765872 scopus 로고    scopus 로고
    • Potentiation of vascular oxidative stress and nitric oxide-mediated endothelial dysfunction by high-fat diet in a mouse model of estrogen deficiency and hyperandrogenemia
    • D. Javeshghani, E.L. Schiffrin, M.R. Sairam, and R.M. Touyz Potentiation of vascular oxidative stress and nitric oxide-mediated endothelial dysfunction by high-fat diet in a mouse model of estrogen deficiency and hyperandrogenemia J Am Soc Hypertens 3 5 2009 295 305
    • (2009) J Am Soc Hypertens , vol.3 , Issue.5 , pp. 295-305
    • Javeshghani, D.1    Schiffrin, E.L.2    Sairam, M.R.3    Touyz, R.M.4
  • 27
    • 77954589341 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists as neuroprotective agents
    • R.K. Kaundal, and S.S. Sharma Peroxisome proliferator-activated receptor gamma agonists as neuroprotective agents Drug News Perspect 23 4 2010 241 256
    • (2010) Drug News Perspect , vol.23 , Issue.4 , pp. 241-256
    • Kaundal, R.K.1    Sharma, S.S.2
  • 28
    • 70049089859 scopus 로고    scopus 로고
    • Exploring mechanism of pioglitazone-induced memory restorative effect in experimental dementia
    • B. Kaur, N. Singh, and A.S. Jaggi Exploring mechanism of pioglitazone-induced memory restorative effect in experimental dementia Fundam Clin Pharmacol 23 2009 557 566
    • (2009) Fundam Clin Pharmacol , vol.23 , pp. 557-566
    • Kaur, B.1    Singh, N.2    Jaggi, A.S.3
  • 29
    • 65249171384 scopus 로고    scopus 로고
    • Vascular structure and function is correlated to cognitive performance and white matter hyperintensities in older hypertensive patients with subjective memory complaints
    • A. Kearney-Schwartz, P. Rossignol, S. Bracard, J. Felblinger, R. Fay, and J.M. Boivin Vascular structure and function is correlated to cognitive performance and white matter hyperintensities in older hypertensive patients with subjective memory complaints Stroke 40 4 2009 1229 1236
    • (2009) Stroke , vol.40 , Issue.4 , pp. 1229-1236
    • Kearney-Schwartz, A.1    Rossignol, P.2    Bracard, S.3    Felblinger, J.4    Fay, R.5    Boivin, J.M.6
  • 30
    • 44049091481 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors-gamma in amyotrophic lateral sclerosis and Huntington's disease
    • M. Kiaei Peroxisome proliferator-activated receptors-gamma in amyotrophic lateral sclerosis and Huntington's disease PPAR Res 2008 2008 418765
    • (2008) PPAR Res , vol.2008 , pp. 418765
    • Kiaei, M.1
  • 32
    • 51349101107 scopus 로고    scopus 로고
    • Ameliorative role of atorvastatin and pitavastatin in L-methionine induced vascular dementia in rats
    • R.U. Koladiya, A.S. Jaggi, N. Singh, and B.K. Sharma Ameliorative role of atorvastatin and pitavastatin in L-methionine induced vascular dementia in rats BMC Pharmacol 8 2008 14
    • (2008) BMC Pharmacol , vol.8 , pp. 14
    • Koladiya, R.U.1    Jaggi, A.S.2    Singh, N.3    Sharma, B.K.4
  • 33
    • 66249119736 scopus 로고    scopus 로고
    • Beneficial effects of donepezil on vascular endothelial dysfunction-associated dementia induced by L-methionine in rats
    • R.U. Koladiya, A.S. Jaggi, N. Singh, and B. Sharma Beneficial effects of donepezil on vascular endothelial dysfunction-associated dementia induced by L-methionine in rats J Health Sci 55 2 2009 215 225
    • (2009) J Health Sci , vol.55 , Issue.2 , pp. 215-225
    • Koladiya, R.U.1    Jaggi, A.S.2    Singh, N.3    Sharma, B.4
  • 34
    • 77950555454 scopus 로고    scopus 로고
    • The effect of the PPAR-gamma agonist rosiglitazone on neuroblastoma SK-N-SH cells in a metastatic xenograft mouse model
    • N. Krieger-Hinck, U. Schumacher, A. Muller, and U. Valentiner The effect of the PPAR-gamma agonist rosiglitazone on neuroblastoma SK-N-SH cells in a metastatic xenograft mouse model Oncol Res 18 2010 387 393
    • (2010) Oncol Res , vol.18 , pp. 387-393
    • Krieger-Hinck, N.1    Schumacher, U.2    Muller, A.3    Valentiner, U.4
  • 35
    • 76349124070 scopus 로고    scopus 로고
    • The PPAR-gamma agonist darglitazone restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse
    • R. Kumari, L.B. Willing, S.D. Patel, J.K. Krady, W.J. Zavadoski, and E.M. Gibbs The PPAR-gamma agonist darglitazone restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse J Cereb Blood Flow Metab 30 2010 352 360
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 352-360
    • Kumari, R.1    Willing, L.B.2    Patel, S.D.3    Krady, J.K.4    Zavadoski, W.J.5    Gibbs, E.M.6
  • 36
    • 34147102288 scopus 로고    scopus 로고
    • Therapeutic use of agonists of the nuclear receptor PPARγ in Alzheimer's disease
    • DOI 10.2174/156720507780362092
    • G. Landreth Therapeutic use of agonists of the nuclear receptors PPARgamma in Alzheimer's disease Curr Alzheimer Res 4 2007 159 164 (Pubitemid 46557505)
    • (2007) Current Alzheimer Research , vol.4 , Issue.2 , pp. 159-164
    • Landreth, G.1
  • 37
    • 46749115113 scopus 로고    scopus 로고
    • PPARγ Agonists as Therapeutics for the Treatment of Alzheimer's Disease
    • DOI 10.1016/j.nurt.2008.05.003, PII S1933721308000925
    • G. Landreth, Q. Jiang, S. Mandrekar, and M. Heneka PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease Neurotherapeutics 5 2008 481 489 (Pubitemid 351952487)
    • (2008) Neurotherapeutics , vol.5 , Issue.3 , pp. 481-489
    • Landreth, G.1    Jiang, Q.2    Mandrekar, S.3    Heneka, M.4
  • 38
    • 77954624657 scopus 로고    scopus 로고
    • Attenuated alpha-adrenoceptor-mediated arterial and venous constrictions in rat models of diabetes
    • J.Y. Leung, E.W. Kwok, G.Y. Liu, and C.C. Pang Attenuated alpha-adrenoceptor-mediated arterial and venous constrictions in rat models of diabetes Eur J Pharmacol 642 1-3 2010 128 133
    • (2010) Eur J Pharmacol , vol.642 , Issue.13 , pp. 128-133
    • Leung, J.Y.1    Kwok, E.W.2    Liu, G.Y.3    Pang, C.C.4
  • 39
    • 80051687247 scopus 로고    scopus 로고
    • Protective effect of the peroxisome proliferator-activated receptors PPAR-gamma ligand rosiglitazone on tert-butyl hydroperoxide-induced QZG cell injury
    • W.L. Li, X. Liang, X. Wang, X.D. Zhang, R. Liu, and W. Zhang Protective effect of the peroxisome proliferator-activated receptors PPAR-gamma ligand rosiglitazone on tert-butyl hydroperoxide-induced QZG cell injury Exp Toxicol Pathol 63 6 2011 527 533
    • (2011) Exp Toxicol Pathol , vol.63 , Issue.6 , pp. 527-533
    • Li, W.L.1    Liang, X.2    Wang, X.3    Zhang, X.D.4    Liu, R.5    Zhang, W.6
  • 40
    • 77953284657 scopus 로고    scopus 로고
    • The MTHFR C677T polymorphism contributes to an increased risk for vascular dementia: A meta-analysis
    • H. Liu, M. Yang, G.M. Li, Y. Qiu, J. Zheng, and X. Du The MTHFR C677T polymorphism contributes to an increased risk for vascular dementia: a meta-analysis J Neurol Sci 294 2010 74 80
    • (2010) J Neurol Sci , vol.294 , pp. 74-80
    • Liu, H.1    Yang, M.2    Li, G.M.3    Qiu, Y.4    Zheng, J.5    Du, X.6
  • 42
    • 77954559472 scopus 로고    scopus 로고
    • Type 2 diabetes and related conditions in relation to dementia: An opportunity for prevention?
    • J.A. Luchsinger Type 2 diabetes and related conditions in relation to dementia: an opportunity for prevention? J Alzheimers Dis 20 3 2010 723 736
    • (2010) J Alzheimers Dis , vol.20 , Issue.3 , pp. 723-736
    • Luchsinger, J.A.1
  • 43
    • 77953704219 scopus 로고    scopus 로고
    • Chui DH protective effect of a poly-phytocompound on early stage nephropathy secondary to experimentally-induced diabetes
    • F. Marotta, M. Harada, E.D. Dallah, H. Yadav, U. Solimene, and S. Di Lembo Chui DH protective effect of a poly-phytocompound on early stage nephropathy secondary to experimentally-induced diabetes J Biol Regul Homeost Agents 24 1 2010 41 49
    • (2010) J Biol Regul Homeost Agents , vol.24 , Issue.1 , pp. 41-49
    • Marotta, F.1    Harada, M.2    Dallah, E.D.3    Yadav, H.4    Solimene, U.5    Di Lembo, S.6
  • 44
    • 0021173996 scopus 로고
    • Developments of a water maze producer for studying spatial learning in the rats
    • R.G.M. Morris Developments of a water maze producer for studying spatial learning in the rats J Neurosci Methods 11 1984 47 60
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.G.M.1
  • 45
    • 55249125525 scopus 로고    scopus 로고
    • Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone a peroxisome proliferator-activated receptors gamma agonist
    • N. Nicolakakis, T. Aboulkassim, B. Ongali, C. Lecrux, P. Fernandes, and P. Rosa-Neto Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone a peroxisome proliferator-activated receptors gamma agonist J Neurosci 28 2008 9287 9296
    • (2008) J Neurosci , vol.28 , pp. 9287-9296
    • Nicolakakis, N.1    Aboulkassim, T.2    Ongali, B.3    Lecrux, C.4    Fernandes, P.5    Rosa-Neto, P.6
  • 46
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • H. Ohokawa, N. Ohishi, and K. Yagi Assay for lipid peroxided in animal tissues by thiobarbituric acid reaction Anal Biochem 95 1979 351 358 (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 47
    • 77956547219 scopus 로고    scopus 로고
    • Apocynin restores endothelial dysfunction in streptozotocin diabetic rats through regulation of nitric oxide synthase and NADPH oxidase expressions
    • M. Olukman, C.E. Orhan, F.G. Celenk, and S. Ulker Apocynin restores endothelial dysfunction in streptozotocin diabetic rats through regulation of nitric oxide synthase and NADPH oxidase expressions J Diabetes Complications 24 6 2010 415 423
    • (2010) J Diabetes Complications , vol.24 , Issue.6 , pp. 415-423
    • Olukman, M.1    Orhan, C.E.2    Celenk, F.G.3    Ulker, S.4
  • 48
    • 77952404321 scopus 로고    scopus 로고
    • The role of oxidative stress and endothelial injury in diabetic neuropathy and neuropathic pain
    • A. Ozkul, M. Ayhan, C. Yenisey, A. Akyol, E. Guney, and F.A. Ergin The role of oxidative stress and endothelial injury in diabetic neuropathy and neuropathic pain Neuro Endocrinol Lett 31 2 2010 261 264
    • (2010) Neuro Endocrinol Lett , vol.31 , Issue.2 , pp. 261-264
    • Ozkul, A.1    Ayhan, M.2    Yenisey, C.3    Akyol, A.4    Guney, E.5    Ergin, F.A.6
  • 49
    • 0030238340 scopus 로고    scopus 로고
    • Effects of intrastriatal injections of platelet-activating factor and the PAF antagonist BA 52021 on memory
    • DOI 10.1006/nlme.1996.0058
    • M.G. Packard, L.A. Teather, and N.G. Bazan Effect of intra-striated injectins of platelet-activating factor and PAF antagonist BN 52021 on memory Neurol Learn Mem 66 1996 176 182 (Pubitemid 26423877)
    • (1996) Neurobiology of Learning and Memory , vol.66 , Issue.2 , pp. 176-182
    • Packard, M.G.1    Teather, L.A.2    Bazan, N.G.3
  • 50
    • 77956437923 scopus 로고    scopus 로고
    • Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats
    • L. Pari, and S. Srinivasan Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats Biomed Pharmacother 64 7 2010 477 481
    • (2010) Biomed Pharmacother , vol.64 , Issue.7 , pp. 477-481
    • Pari, L.1    Srinivasan, S.2
  • 51
    • 34447132931 scopus 로고    scopus 로고
    • Reversal of memory deficits by atorvastatin and simvastatin in rats
    • DOI 10.1248/yakushi.127.1125
    • M. Parle, and N. Singh Reversal of memory deficits by atorvastatin and simvastatin in rats Yakugaku Zasshi 127 2007 1125 1137 (Pubitemid 47035644)
    • (2007) Yakugaku Zasshi , vol.127 , Issue.7 , pp. 1125-1137
    • Parle, M.1    Singh, N.2
  • 52
    • 0034711678 scopus 로고    scopus 로고
    • Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators
    • V. Pasceri, H.D. Wu, J.T. Willerson, and E.T. Yeh Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptorgamma activators Circulation 101 2000 235 238 (Pubitemid 30054148)
    • (2000) Circulation , vol.101 , Issue.3 , pp. 235-238
    • Pasceri, V.1    Wu, H.D.2    Willerson, J.T.3    Yeh, E.T.H.4
  • 53
    • 33750454798 scopus 로고    scopus 로고
    • Chronic administration of pioglitazone attenuates intracerebroventricular streptozotocin induced-memory impairment in rats
    • DOI 10.1016/j.lfs.2006.07.018, PII S002432050600573X
    • A.R. Pathan, B. Viswanad, S.K. Sonkusare, and P. Ramarao Chronic administration of pioglitazone attenuates intracerebroventricular streptozotocin induced-memory impairment in rats Life Sci 79 2006 2209 2216 (Pubitemid 44646475)
    • (2006) Life Sciences , vol.79 , Issue.23 , pp. 2209-2216
    • Pathan, A.R.1    Viswanad, B.2    Sonkusare, S.K.3    Ramarao, P.4
  • 54
    • 0030900360 scopus 로고    scopus 로고
    • Diabetic-induced endothelial dysfunction in rat aorta: Role of hydroxyl radicals
    • DOI 10.1016/S0008-6363(96)00237-4, PII S0008636396002374
    • G.M. Pieper Diabetic induced endothelial dysfunction in rat aorta: role of hydroxyl radicals Cardiovasc Res 34 1997 145 156 (Pubitemid 27261923)
    • (1997) Cardiovascular Research , vol.34 , Issue.1 , pp. 145-156
    • Pieper, G.M.1    Langenstroer, P.2    Siebeneich, W.3
  • 55
    • 24144448954 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor γ-dependent mechanisms
    • DOI 10.1161/01.ATV.0000177805.65864.d4
    • J.A. Polikandriotis, L.J. Mazzella, H.L. Rupnow, and C.M. Hart Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms Arterioscler Thromb Vasc Biol 25 2005 1810 1816 (Pubitemid 41243447)
    • (2005) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.25 , Issue.9 , pp. 1810-1816
    • Polikandriotis, J.A.1    Mazzella, L.J.2    Rupnow, H.L.3    Hart, C.M.4
  • 56
    • 73649197648 scopus 로고
    • Studies on the diabetogenic action of streptozotocin NSC-37917
    • N. Rakieten, M.L. Rakieten, and M.V. Nandkarni Studies on the diabetogenic action of streptozotocin NSC-37917 Cancer Chemother Rep 29 1963 91 98
    • (1963) Cancer Chemother Rep , vol.29 , pp. 91-98
    • Rakieten, N.1    Rakieten, M.L.2    Nandkarni, M.V.3
  • 57
    • 77958137681 scopus 로고    scopus 로고
    • Delivery of SAR 1118 to retina via ophthalmic drops and its effectiveness in reduction of retinal leukostasis and vascular leakiness in rat streptozotocin STZ model of diabetic retinopathy DR
    • V.R. Rao, E. Prescott, N.B. Shelke, R. Trivedi, P. Thomas, and C. Struble Delivery of SAR 1118 to retina via ophthalmic drops and its effectiveness in reduction of retinal leukostasis and vascular leakiness in rat streptozotocin STZ model of diabetic retinopathy DR Invest Ophthalmol Vis Sci 51 10 2010 5198 5204
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.10 , pp. 5198-5204
    • Rao, V.R.1    Prescott, E.2    Shelke, N.B.3    Trivedi, R.4    Thomas, P.5    Struble, C.6
  • 58
    • 0032737858 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptorγ (PPARγ) as a regulator of monocyte/macrophage function
    • M. Ricote, J.T. Huang, J.S. Welch, and C.K. Glass The peroxisome proloferator receptor gamma as a regulator of monocyte/macrophage function J Leukoc Biol 66 1999 733 739 (Pubitemid 29532032)
    • (1999) Journal of Leukocyte Biology , vol.66 , Issue.5 , pp. 733-739
    • Ricote, M.1    Huang, J.T.2    Welch, J.S.3    Glass, C.K.4
  • 60
    • 59649109871 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptors-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis
    • D.A. Sarruf, F. Yu, H.T. Nguyen, D.L. Williams, R.L. Printz, and K.D. Niswender Expression of peroxisome proliferator-activated receptors-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis Endocrinology 150 2009 707 712
    • (2009) Endocrinology , vol.150 , pp. 707-712
    • Sarruf, D.A.1    Yu, F.2    Nguyen, H.T.3    Williams, D.L.4    Printz, R.L.5    Niswender, K.D.6
  • 61
    • 0036629201 scopus 로고    scopus 로고
    • Spectrophotometric determination of serum nitrite and nitrate by copper-cadmium alloy
    • DOI 10.1006/abio.2002.5676
    • K.V. Sastry, R.P. Moudgal, J. Mohan, J.S. Tyagi, and G.S. Rao Spectrophotometric determination of serum nitrite and nitrate by copper-cadmium alloy Anal Biochem 306 1 2002 79 82 (Pubitemid 34722019)
    • (2002) Analytical Biochemistry , vol.306 , Issue.1 , pp. 79-82
    • Sastry, K.V.H.1    Moudgal, R.P.2    Mohan, J.3    Tyagi, J.S.4    Rao, G.S.5
  • 63
    • 61449237400 scopus 로고    scopus 로고
    • PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease
    • N. Schintu, L. Frau, M. Ibba, P. Caboni, A. Garau, and E. Carboni PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease Eur J Neurosci 29 2009 954 963
    • (2009) Eur J Neurosci , vol.29 , pp. 954-963
    • Schintu, N.1    Frau, L.2    Ibba, M.3    Caboni, P.4    Garau, A.5    Carboni, E.6
  • 64
    • 77955345949 scopus 로고    scopus 로고
    • Lifestyle-related diseases as risk factors for dementia
    • A. Sekita, and Y. Kiyohara Lifestyle-related diseases as risk factors for dementia Brain Nerve 62 7 2010 709 717
    • (2010) Brain Nerve , vol.62 , Issue.7 , pp. 709-717
    • Sekita, A.1    Kiyohara, Y.2
  • 65
    • 77956546678 scopus 로고    scopus 로고
    • Pitavastatin and 4′-Hydroxy-3′-methoxyacetophenone HMAP reduce cognitive dysfunction in vascular dementia during experimental diabetes
    • B. Sharma, and N. Singh Pitavastatin and 4′-Hydroxy-3′- methoxyacetophenone HMAP reduce cognitive dysfunction in vascular dementia during experimental diabetes Curr Neurovasc Res 7 2010 180 191
    • (2010) Curr Neurovasc Res , vol.7 , pp. 180-191
    • Sharma, B.1    Singh, N.2
  • 66
    • 80052259171 scopus 로고    scopus 로고
    • Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats
    • B. Sharma, and N. Singh Attenuation of vascular dementia by sodium butyrate in streptozotocin diabetic rats Psychopharmacology (Berl) 215 4 2011 677 687
    • (2011) Psychopharmacology (Berl) , vol.215 , Issue.4 , pp. 677-687
    • Sharma, B.1    Singh, N.2
  • 67
    • 41949102996 scopus 로고    scopus 로고
    • Exploration of HIV protease inhibitor indinavir as a memory restorative agent in experimental induced dementia
    • B. Sharma, N. Singh, and A.S. Jaggi Exploration of HIV protease inhibitor indinavir as a memory restorative agent in experimental induced dementia Pharmacol Biochem Behav 89 2008 535 545
    • (2008) Pharmacol Biochem Behav , vol.89 , pp. 535-545
    • Sharma, B.1    Singh, N.2    Jaggi, A.S.3
  • 68
    • 40049096164 scopus 로고    scopus 로고
    • Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by pitavastatin and donepezil
    • DOI 10.1177/0269881107081553
    • B. Sharma, N. Singh, and M. Singh Modulation of celecoxib and streptozotocin-induced experimental dementia of Alzheimer's disease type by pitavastatin and donepezil J Psychopharmacol 22 2008 162 171 (Pubitemid 351322854)
    • (2008) Journal of Psychopharmacology , vol.22 , Issue.2 , pp. 162-171
    • Sharma, B.1    Singh, N.2    Singh, M.3
  • 69
    • 77954767650 scopus 로고    scopus 로고
    • Influence of metformin on GLUT1 gene and protein expression in rat streptozotocin diabetes mellitus model
    • J. Sokolovska, S. Isajevs, O. Sugoka, J. Sharipova, L. Lauberte, and D. Svirina Influence of metformin on GLUT1 gene and protein expression in rat streptozotocin diabetes mellitus model Arch Physiol Biochem 116 3 2010 137 145
    • (2010) Arch Physiol Biochem , vol.116 , Issue.3 , pp. 137-145
    • Sokolovska, J.1    Isajevs, S.2    Sugoka, O.3    Sharipova, J.4    Lauberte, L.5    Svirina, D.6
  • 70
    • 69249215302 scopus 로고    scopus 로고
    • Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes
    • K. Tsuchiya, I. Akaza, T. Yoshimoto, and Y. Hirata Pioglitazone improves endothelial function with increased adiponectin and high-density lipoprotein cholesterol levels in type 2 diabetes Endocr J 56 5 2009 691 698
    • (2009) Endocr J , vol.56 , Issue.5 , pp. 691-698
    • Tsuchiya, K.1    Akaza, I.2    Yoshimoto, T.3    Hirata, Y.4
  • 71
    • 77949394652 scopus 로고    scopus 로고
    • Pathophysiology of cognitive dysfunction in older people with type 2 diabetes: Vascular changes or neurodegeneration?
    • H. Umegaki Pathophysiology of cognitive dysfunction in older people with type 2 diabetes: vascular changes or neurodegeneration? Age Ageing 39 2010 8 10
    • (2010) Age Ageing , vol.39 , pp. 8-10
    • Umegaki, H.1
  • 72
    • 2942670612 scopus 로고    scopus 로고
    • PPARγ agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: Role of diacylglycerol kinase
    • DOI 10.1161/01.RES.0000130527.92537.06
    • E. Verrier, L. Wang, C. Wadham, N. Albanese, C. Hahn, and J.R. Gamble PPARgamma agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: role of diacylglycerol kinase Circ Res 94 2004 1515 1522 (Pubitemid 38780325)
    • (2004) Circulation Research , vol.94 , Issue.11 , pp. 1515-1522
    • Verrier, E.1    Wang, L.2    Wadham, C.3    Albanese, N.4    Hahn, C.5    Gamble, J.R.6    Chatterjee, V.K.K.7    Vadas, M.A.8    Xia, P.9
  • 73
    • 60549098398 scopus 로고    scopus 로고
    • Vascular risk factors and dementia how to move forward
    • A. Viswanathan, W.A. Rocca, and C. Tzourio Vascular risk factors and dementia how to move forward Neurology 72 2009 368 374
    • (2009) Neurology , vol.72 , pp. 368-374
    • Viswanathan, A.1    Rocca, W.A.2    Tzourio, C.3
  • 74
    • 0014791552 scopus 로고
    • Red cell and plasma cholinesterase activities in microsamples of human and animal blood determined simultaneously by a modified acetylthiocholine / DTNB Procedure
    • G. Voss, and K. Sachsse Red cell and plasma cholinesterase activities in microsamples of human and animal blood determined simultaneously by a modified acetylthiocholine / DTNB Procedure Toxicol Appl Pharmacol 16 1970 764 772
    • (1970) Toxicol Appl Pharmacol , vol.16 , pp. 764-772
    • Voss, G.1    Sachsse, K.2
  • 76
    • 79958027663 scopus 로고    scopus 로고
    • Statins: Multiple neuroprotective mechanisms in neurodegenerative diseases
    • Q. Wang, J. Yan, X. Chen, J. Li, Y. Yang, and J. Weng Statins: multiple neuroprotective mechanisms in neurodegenerative diseases Exp Neurol 230 1 2011 27 34
    • (2011) Exp Neurol , vol.230 , Issue.1 , pp. 27-34
    • Wang, Q.1    Yan, J.2    Chen, X.3    Li, J.4    Yang, Y.5    Weng, J.6
  • 77
    • 77956395196 scopus 로고    scopus 로고
    • Oxidative stress and vascular function: Implications for pharmacologic treatments
    • A.R. Weseler, and A. Bast Oxidative stress and vascular function: implications for pharmacologic treatments Curr Hypertens Rep 12 3 2010 154 161
    • (2010) Curr Hypertens Rep , vol.12 , Issue.3 , pp. 154-161
    • Weseler, A.R.1    Bast, A.2
  • 78
    • 67349163186 scopus 로고    scopus 로고
    • 3′4′-Dihydroxyflavonol prevents diabetes-induced endothelial dysfunction in rat aorta
    • O.L. Woodman, and W. Malakul 3′4′-Dihydroxyflavonol prevents diabetes-induced endothelial dysfunction in rat aorta Life Sci 85 1-2 2009 54 59
    • (2009) Life Sci , vol.85 , Issue.12 , pp. 54-59
    • Woodman, O.L.1    Malakul, W.2
  • 79
    • 42649120119 scopus 로고    scopus 로고
    • Oral administration of grape seed proanthocyanidin extracts downregulate RAGE dependant nuclear factor- kappa BP65 expression in the hippocampus of streptozotocin induced diabetic rats
    • DOI 10.1055/s-2007-993188
    • L. Xu, B. Li, M. Cheng, J. Pan, C. Zhang, and H. Gao Oral administration of grape seed proanthocyanidin extracts downregulate RAGE dependant nuclear factor - kappa BP65 expression in the hippocampus of streptozotocin induced diabetic rats Exp Clin Endocrinol Diabetes 116 4 2008 215 224 (Pubitemid 351600583)
    • (2008) Experimental and Clinical Endocrinology and Diabetes , vol.116 , Issue.4 , pp. 215-224
    • Xu, L.1    Li, B.2    Cheng, M.3    Zhang, W.4    Pan, J.5    Zhang, C.6    Gao, H.7
  • 80
    • 77649123864 scopus 로고    scopus 로고
    • Molecular targets for diabetes mellitus-associated erectile dysfunction
    • E. Yohannes, J. Chang, M.T. Tar, K.P. Davies, and M.R. Chance Molecular targets for diabetes mellitus-associated erectile dysfunction Mol Cell Proteomics 9 3 2010 565 578
    • (2010) Mol Cell Proteomics , vol.9 , Issue.3 , pp. 565-578
    • Yohannes, E.1    Chang, J.2    Tar, M.T.3    Davies, K.P.4    Chance, M.R.5
  • 81
    • 77749301731 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors-gamma PPARgamma agonist improves coronary artery endothelial function in diabetic patients with coronary artery disease
    • J. Yu, Z. Zhang, Z. Li, X. Feng, L. He, and S. Liu Peroxisome proliferator-activated receptors-gamma PPARgamma agonist improves coronary artery endothelial function in diabetic patients with coronary artery disease J Int Med Res 38 2010 86 94
    • (2010) J Int Med Res , vol.38 , pp. 86-94
    • Yu, J.1    Zhang, Z.2    Li, Z.3    Feng, X.4    He, L.5    Liu, S.6
  • 82
    • 77956601141 scopus 로고    scopus 로고
    • PPARgamma agonist rosiglitazone is neuroprotective after traumatic spinal cord injury via anti-inflammatory in adult rats
    • PMID: 20350367 [Epub ahead of print]
    • Q. Zhang, W. Hu, B. Meng, and T. Tang PPARgamma agonist rosiglitazone is neuroprotective after traumatic spinal cord injury via anti-inflammatory in adult rats Neurol Res 2010 PMID: 20350367 [Epub ahead of print]
    • (2010) Neurol Res
    • Zhang, Q.1    Hu, W.2    Meng, B.3    Tang, T.4
  • 83
    • 77952880608 scopus 로고    scopus 로고
    • Diabetes synergistically exacerbates poststroke dementia and tau abnormality in brain
    • T. Zhang, B.S. Pan, G.C. Sun, X. Sun, and F.Y. Sun Diabetes synergistically exacerbates poststroke dementia and tau abnormality in brain Neurochem Int 56 8 2010 955 961
    • (2010) Neurochem Int , vol.56 , Issue.8 , pp. 955-961
    • Zhang, T.1    Pan, B.S.2    Sun, G.C.3    Sun, X.4    Sun, F.Y.5
  • 84
    • 66049135616 scopus 로고    scopus 로고
    • Neuronal PPARgamma deficiency increases susceptibility to brain damage after cerebral ischemia
    • X. Zhao, R. Strong, J. Zhang, G. Sun, J.Z. Tsien, and Z. Cui Neuronal PPARgamma deficiency increases susceptibility to brain damage after cerebral ischemia J Neurosci 29 2009 6186 6195
    • (2009) J Neurosci , vol.29 , pp. 6186-6195
    • Zhao, X.1    Strong, R.2    Zhang, J.3    Sun, G.4    Tsien, J.Z.5    Cui, Z.6
  • 85
    • 34447651352 scopus 로고    scopus 로고
    • Expression changes of growth-associated protein-43 (GAP-43) and mitogen-activated protein kinase phosphatase-1 (MKP-1) and in hippocampus of streptozotocin-induced diabetic cognitive impairment rats
    • DOI 10.1016/j.expneurol.2007.04.013, PII S0014488607001690
    • J. Zhou, L. Wang, S. Ling, and X. Zhang Expression changes of growth-associated protein-43 GAP-43 and mitogen-activated protein kinase phosphatase-1 MKP-1 and in hippocampus of streptozotocin-induced diabetic cognitive impairment rats Exp Neurol 206 2 2007 201 208 (Pubitemid 47094764)
    • (2007) Experimental Neurology , vol.206 , Issue.2 , pp. 201-208
    • Zhou, J.1    Wang, L.2    Ling, S.3    Zhang, X.4


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