Sudden Cardiac Death Among Hemodialysis Patients

American Journal of Kidney Diseases

Volumn 69, Issue 5, 2017, Pages 684-695

  Makar, Melissa S ^a,b   Pun, Patrick H ^a,b  

^a DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

arrhythmia; dialysis; end stage kidney disease; end stage renal disease (ESRD); hemodialysis; pathogenesis; pathophysiology; prevention; prevention strategies; review; risk factors; Sudden cardiac death (SCD); sudden death

Indexed keywords

CALCIUM; CARDIAC AGENT; POTASSIUM; HEMODIALYSIS FLUID;

ADULT; AFRICAN AMERICAN; AORTIC VALVE PROSTHESIS; AORTIC VALVE REPLACEMENT; ARTICLE; AUTOMATED EXTERNAL DEFIBRILLATOR; BACTERIAL ENDOCARDITIS; CASE REPORT; CORONARY ARTERY; DIALYSATE; DIASTOLIC DYSFUNCTION; GLOMERULOPATHY; HEART ARREST; HEART VENTRICLE FIBRILLATION; HEMODIALYSIS; HEMODIALYSIS PATIENT; HUMAN; HYPOTENSION; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; MALE; OBESITY; PAROXYSMAL ATRIAL FIBRILLATION; PATHOPHYSIOLOGY; PRESCRIPTION; PRIMARY PREVENTION; RESUSCITATION; RISK FACTOR; SUDDEN CARDIAC DEATH; SURVIVAL; SYSTOLIC DYSFUNCTION; TREATMENT DURATION; ULTRAFILTRATION; WEIGHT GAIN; ARRHYTHMIAS, CARDIAC; CHEMISTRY; DEATH, SUDDEN, CARDIAC; HEART LEFT VENTRICLE HYPERTROPHY; KIDNEY FAILURE, CHRONIC; METABOLISM; PROCEDURES; VASCULAR CALCIFICATION;

ADULT; ARRHYTHMIAS, CARDIAC; CALCIUM; DEATH, SUDDEN, CARDIAC; DEFIBRILLATORS, IMPLANTABLE; HEMODIALYSIS SOLUTIONS; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; KIDNEY FAILURE, CHRONIC; MALE; POTASSIUM; RENAL DIALYSIS; RISK FACTORS; VASCULAR CALCIFICATION;

EID: 85013029016     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2016.12.006     Document Type: Article

References (101)

1. 1 Saran, R., Li, Y., Robinson, B., et al. US Renal Data System 2014 Annual Data Report: epidemiology of kidney disease in the United States. Am J Kidney Dis, 66(1 suppl 1), 2015.
2. 2 Jadoul, M., Thumma, J., Fuller, D.S., et al. Modifiable practices associated with sudden death among hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study. Clin J Am Soc Nephrol 7:5 (2012), 765–774.
3. 3 Hinkle, L.E. Jr., Thaler, H.T., Clinical classification of cardiac deaths. Circulation 65:3 (1982), 457–464.
4. 4 Mann, D.L., Zipes, D.P., Libby, P., Bonow, R.O., Braunwald, E., Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed., 2015, Elsevier/Saunders, Philadelphia, PA http://getitatduke.library.duke.edu/?sid=sersol&SS_jc=TC0001535525&title=Braunwald%27s%20heart%20disease%20%3A%20a%20textbook%20of%20cardiovascular%20medicine Accessed December 5, 2016.
5. 5 Herzog, C.A., Asinger, R.W., Berger, A.K., et al. Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int 80:6 (2011), 572–586.
6. 6 Writing Group Members, Mozaffarian, D., Benjamin, E.J., Go, A.S., et al. Heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation 133:4 (2016), e38–e360.
7. 7 Takeda, K., Harada, A., Okuda, S., et al. Sudden death in chronic dialysis patients. Nephrol Dial Transplant 12:5 (1997), 952–955.
8. 8 Herzog, C.A., Cardiac arrest in dialysis patients: approaches to alter an abysmal outcome. Kidney Int Suppl 84 (2003), S197–S200.
9. 9 Bleyer, A.J., Hartman, J., Brannon, P.C., Reeves-Daniel, A., Satko, S.G., Russell, G., Characteristics of sudden death in hemodialysis patients. Kidney Int 69:12 (2006), 2268–2273.
10. 10 Ramesh, S., Zalucky, A., Hemmelgarn, B.R., et al. Incidence of sudden cardiac death in adults with end-stage renal disease: a systematic review and meta-analysis. BMC Nephrol, 17(1), 2016, 78.
11. 11 Pun, P.H., Herzog, C.A., Middleton, J.P., Improving ascertainment of sudden cardiac death in patients with end stage renal disease. Clin J Am Soc Nephrol 7:1 (2012), 116–122.
12. 12 Cheung, A.K., Sarnak, M.J., Yan, G., et al. Cardiac diseases in maintenance hemodialysis patients: results of the HEMO Study. Kidney Int 65:6 (2004), 2380–2389.
13. 13 Wanner, C., Krane, V., Marz, W., et al. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 353:3 (2005), 238–248.
14. 14 Wheeler, D.C., London, G.M., Parfrey, P.S., et al. Effects of cinacalcet on atherosclerotic and nonatherosclerotic cardiovascular events in patients receiving hemodialysis: the EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events (EVOLVE) trial. J Am Heart Assoc, 3(6), 2014, e001363.
15. 15 Rocco, M.V., Yan, G., Gassman, J., et al. Comparison of causes of death using HEMO Study and HCFA end-stage renal disease death notification classification systems. The National Institutes of Health-funded Hemodialysis. Health Care Financing Administration. Am J Kidney Dis 39:1 (2002), 146–153.
16. 16 Huikuri, H.V., Castellanos, A., Myerburg, R.J., Sudden death due to cardiac arrhythmias. N Engl J Med 345:20 (2001), 1473–1482.
17. 17 Bayes de Luna, A., Coumel, P., Leclercq, J.F., Ambulatory sudden cardiac death: mechanisms of production of fatal arrhythmia on the basis of data from 157 cases. Am Heart J 117:1 (1989), 151–159.
18. 18 Priori, S.G., Blomstrom-Lundqvist, C., Mazzanti, A., et al. 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: the Task Force for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC). Eur Heart J 36:41 (2015), 2793–2867.
19. 19 Ohtake, T., Kobayashi, S., Moriya, H., et al. High prevalence of occult coronary artery stenosis in patients with chronic kidney disease at the initiation of renal replacement therapy: an angiographic examination. J Am Soc Nephrol 16:4 (2005), 1141–1148.
20. 20 Lowrie, E.G., Lew, N.L., Death risk in hemodialysis patients: the predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis 15:5 (1990), 458–482.
21. 21 Kalantar-Zadeh, K., Block, G., Humphreys, M.H., Kopple, J.D., Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients. Kidney Int 63:3 (2003), 793–808.
22. 22 Zager, P.G., Nikolic, J., Brown, R.H., et al. “U” curve association of blood pressure and mortality in hemodialysis patients. Medical Directors of Dialysis Clinic, Inc. Kidney Int 54:2 (1998), 561–569.
23. 23 Pun, P.H., Smarz, T.R., Honeycutt, E.F., Shaw, L.K., Al-Khatib, S.M., Middleton, J.P., Chronic kidney disease is associated with increased risk of sudden cardiac death among patients with coronary artery disease. Kidney Int 76:6 (2009), 652–658.
24. 24 Genovesi, S., Valsecchi, M.G., Rossi, E., et al. Sudden death and associated factors in a historical cohort of chronic haemodialysis patients. Nephrol Dial Transplant 24:8 (2009), 2529–2536.
25. 25 Yamada, S., Ishii, H., Takahashi, H., et al. Prognostic value of reduced left ventricular ejection fraction at start of hemodialysis therapy on cardiovascular and all-cause mortality in end-stage renal disease patients. Clin J Am Soc Nephrol 5:10 (2010), 1793–1798.
26. 26 Mangrum, A.J., Liu, D., Dimarco, J.P., Bolton, K., Mangrum, M., Sudden cardiac death and left ventricular function in hemodialysis patients. Heart Rhythm, 2(5 suppl), 2005, S33.
27. 27 Paoletti, E., Specchia, C., Di Maio, G., et al. The worsening of left ventricular hypertrophy is the strongest predictor of sudden cardiac death in haemodialysis patients: a 10 year survey. Nephrol Dial Transplant 19:7 (2004), 1829–1834.
28. 28 Mark, P.B., Johnston, N., Groenning, B.A., et al. Redefinition of uremic cardiomyopathy by contrast-enhanced cardiac magnetic resonance imaging. Kidney Int 69:10 (2006), 1839–1845.
29. 29 Schietinger, B.J., Brammer, G.M., Wang, H., et al. Patterns of late gadolinium enhancement in chronic hemodialysis patients. JACC Cardiovasc Imaging 1:4 (2008), 450–456.
30. 30 Amann, K., Breitbach, M., Ritz, E., Mall, G., Myocyte/capillary mismatch in the heart of uremic patients. J Am Soc Nephrol 9:6 (1998), 1018–1022.
31. 31 Burton, J.O., Jefferies, H.J., Selby, N.M., McIntyre, C.W., Hemodialysis-induced cardiac injury: determinants and associated outcomes. Clin J Am Soc Nephrol 4:5 (2009), 914–920.
32. 32 Foley, R.N., Gilbertson, D.T., Murray, T., Collins, A.J., Long interdialytic interval and mortality among patients receiving hemodialysis. N Engl J Med 365:12 (2011), 1099–1107.
33. 33 Wong, M.C., Kalman, J.M., Pedagogos, E., et al. Temporal distribution of arrhythmic events in chronic kidney disease: highest incidence in the long interdialytic period. Heart Rhythm 12:10 (2015), 2047–2055.
34. 34 Krishnasamy, R., Badve, S.V., Hawley, C.M., et al. Daily variation in death in patients treated by long-term dialysis: comparison of in-center hemodialysis to peritoneal and home hemodialysis. Am J Kidney Dis 61:1 (2013), 96–103.
35. 35 Pun, P.H., Lehrich, R.W., Honeycutt, E.F., Herzog, C.A., Middleton, J.P., Modifiable risk factors associated with sudden cardiac arrest within hemodialysis clinics. Kidney Int 79:2 (2011), 218–227.
36. 36 Karnik, J.A., Young, B.S., Lew, N.L., et al. Cardiac arrest and sudden death in dialysis units. Kidney Int 60:1 (2001), 350–357.
37. 37 Movilli, E., Gaggia, P., Zubani, R., et al. Association between high ultrafiltration rates and mortality in uraemic patients on regular haemodialysis. A 5-year prospective observational multicentre study. Nephrol Dial Transplant 22:12 (2007), 3547–3552.
38. 38 Saran, R., Bragg-Gresham, J.L., Levin, N.W., et al. Longer treatment time and slower ultrafiltration in hemodialysis: associations with reduced mortality in the DOPPS. Kidney Int 69:7 (2006), 1222–1228.
39. 39 Flythe, J.E., Brunelli, S.M., The risks of high ultrafiltration rate in chronic hemodialysis: implications for patient care. Semin Dial 24:3 (2011), 259–265.
40. 40 Gabutti, L., Ferrari, N., Giudici, G., Mombelli, G., Marone, C., Unexpected haemodynamic instability associated with standard bicarbonate haemodialysis. Nephrol Dial Transplant 18:11 (2003), 2369–2376.
41. 41 Di Iorio, B., Torraca, S., Piscopo, C., et al. Dialysate bath and QTc interval in patients on chronic maintenance hemodialysis: pilot study of single dialysis effects. J Nephrol 25:5 (2012), 653–660.
42. 42 Pande, S., Raja, R., Bloom, E., Chewaproug, D., Dissanayake, I., Effect of dialysate baths on serum bicarbonate levels in hemodialysis patients. [abstract] Am J Kidney Dis, 57(4), 2011, A75.
43. 43 Chan, K.E., Newton-Cheh, C., Gusella, J.F., Maddux, F.W., Heritability of risk for sudden cardiac arrest in ESRD. J Am Soc Nephrol 26:11 (2015), 2815–2820.
44. 44 Spooner, P.M., Sudden cardiac death: the larger problem… The larger genome. J Cardiovasc Electrophysiol 20:5 (2009), 585–596.
45. 45 Keller, S.P., Halperin, H.R., Cardiac arrest: the changing incidence of ventricular fibrillation. Curr Treat Options Cardiovasc Med, 17(7), 2015, 392.
46. 46 Bonato, F.O., Lemos, M.M., Cassiolato, J.L., Canziani, M.E., Prevalence of ventricular arrhythmia and its associated factors in nondialyzed chronic kidney disease patients. PLoS One, 8(6), 2013, e66036.
47. 47 Hsueh, C.-H.C., Neal, X., Chen, P.-S., Lin, S.F., Moe, S.M., Increased inducibility of ventricular arrhythmia in a rat model of chronic kidney disease. [abstract] J Am Soc Nephrol, 24, 2013, 139A.
48. 48 Wan, C., Herzog, C.A., Zareba, W., Szymkiewicz, S.J., Sudden cardiac arrest in hemodialysis patients with wearable cardioverter defibrillator. Ann Noninvasive Electrocardiol 19:3 (2014), 247–257.
49. 49 Davis, T.R., Young, B.A., Eisenberg, M.S., Rea, T.D., Copass, M.K., Cobb, L.A., Outcome of cardiac arrests attended by emergency medical services staff at community outpatient dialysis centers. Kidney Int 73:8 (2008), 933–939.
50. 50 Lafrance, J.P., Nolin, L., Senecal, L., Leblanc, M., Predictors and outcome of cardiopulmonary resuscitation (CPR) calls in a large haemodialysis unit over a seven-year period. Nephrol Dial Transplant 21:4 (2006), 1006–1012.
51. 51 Verde, E., Perez de Prado, A., Lopez-Gomez, J.M., et al. Asymptomatic intradialytic supraventricular arrhythmias and adverse outcomes in patients on hemodialysis. Clin J Am Soc Nephrol 11:12 (2016), 2210–2217.
52. 52 Charytan, D.M., Foley, R., McCullough, P.A., et al. Arrhythmia and sudden death in hemodialysis patients: protocol and baseline characteristics of the Monitoring in Dialysis Study. Clin J Am Soc Nephrol 11:4 (2016), 721–734.
53. 53 Roy-Chaudhury P, Williamson DE, Tumlin JA, et al. Monitoring in Dialysis (MiD) Study: exploring the timeline and etiology of increased arrhythmias in hemodialysis (HD) patients. Society of Nephrology Kidney Week 2015. San Diego, November 3-8, 2015.
54. 54 Pun, P.H., Lehrich, R.W., Smith, S.R., Middleton, J.P., Predictors of survival after cardiac arrest in outpatient hemodialysis clinics. Clin J Am Soc Nephrol 2:3 (2007), 491–500.
55. 55 Kudenchuk, P.J., Stuart, R., Husain, S., Fahrenbruch, C., Eisenberg, M., Treatment and outcome of out-of-hospital cardiac arrest in outpatient health care facilities. Resuscitation 97 (2015), 97–102.
56. 56 Ganesh, S.K., Stack, A.G., Levin, N.W., Hulbert-Shearon, T., Port, F.K., Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients. J Am Soc Nephrol 12:10 (2001), 2131–2138.
57. 57 Parekh, R.S., Plantinga, L.C., Kao, W.H., et al. The association of sudden cardiac death with inflammation and other traditional risk factors. Kidney Int 74:10 (2008), 1335–1342.
58. 58 Drechsler, C., Krane, V., Winkler, K., Dekker, F.W., Wanner, C., Changes in adiponectin and the risk of sudden death, stroke, myocardial infarction, and mortality in hemodialysis patients. Kidney Int 76:5 (2009), 567–575.
59. 59 Shastri, S., Tangri, N., Tighiouart, H., et al. Predictors of sudden cardiac death: a competing risk approach in the Hemodialysis Study. Clin J Am Soc Nephrol 7:1 (2012), 123–130.
60. 60 Passman, R., Herzog, C.A., End-stage renal disease: sudden cardiac death: stratifying risk in dialysis patients. Nat Rev Nephrol 7:3 (2011), 133–135.
61. 61 Domanski, M.J., Zipes, D.P., Schron, E., Treatment of sudden cardiac death. Current understandings from randomized trials and future research directions. Circulation 95:12 (1997), 2694–2699.
62. 62 Cice, G., Ferrara, L., D'Andrea, A., et al. Carvedilol increases two-year survival in dialysis patients with dilated cardiomyopathy: a prospective, placebo-controlled trial. J Am Coll Cardiol 41:9 (2003), 1438–1444.
63. 63 Agarwal, R., Sinha, A.D., Pappas, M.K., Abraham, T.N., Tegegne, G.G., Hypertension in hemodialysis patients treated with atenolol or lisinopril: a randomized controlled trial. Nephrol Dial Transplant 29:3 (2014), 672–681.
64. 64 Tangri, N., Shastri, S., Tighiouart, H., et al. beta-Blockers for prevention of sudden cardiac death in patients on hemodialysis: a propensity score analysis of the HEMO Study. Am J Kidney Dis 58:6 (2011), 939–945.
65. 65 Fellstrom, B., Zannad, F., Schmieder, R., et al. Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study. Curr Control Trials Cardiovasc Med, 6(1), 2005, 9.
66. 66 Baigent, C., Landray, M.J., Reith, C., et al. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet 377:9784 (2011), 2181–2192.
67. 67 Iseki, K., Arima, H., Kohagura, K., et al. Effects of angiotensin receptor blockade (ARB) on mortality and cardiovascular outcomes in patients with long-term haemodialysis: a randomized controlled trial. Nephrol Dial Transplant 28:6 (2013), 1579–1589.
68. 68 Zannad, F., Kessler, M., Lehert, P., et al. Prevention of cardiovascular events in end-stage renal disease: results of a randomized trial of fosinopril and implications for future studies. Kidney Int 70:7 (2006), 1318–1324.
69. 69 Tai, D.J., Lim, T.W., James, M.T., Manns, B.J., Tonelli, M., Hemmelgarn, B.R., Cardiovascular effects of angiotensin converting enzyme inhibition or angiotensin receptor blockade in hemodialysis: a meta-analysis. Clin J Am Soc Nephrol 5:4 (2010), 623–630.
70. 70 Matsumoto, Y., Mori, Y., Kageyama, S., et al. Spironolactone reduces cardiovascular and cerebrovascular morbidity and mortality in hemodialysis patients. J Am Coll Cardiol 63:6 (2014), 528–536.
71. 71 Santoro, A., Mancini, E., London, G., et al. Patients with complex arrhythmias during and after haemodialysis suffer from different regimens of potassium removal. Nephrol Dial Transplant 23:4 (2008), 1415–1421.
72. 72 Weir, M.R., Bakris, G.L., Bushinsky, D.A., et al. Patiromer in patients with kidney disease and hyperkalemia receiving RAAS inhibitors. N Engl J Med 372:3 (2015), 211–221.
73. 73 Kosiborod, M., Peacock, W.F., Packham, D.K., Sodium zirconium cyclosilicate for urgent therapy of severe hyperkalemia. N Engl J Med 372:16 (2015), 1577–1578.
74. 74 Beaubien, E.R., Pylypchuk, G.B., Akhtar, J., Biem, H.J., Value of corrected QT interval dispersion in identifying patients initiating dialysis at increased risk of total and cardiovascular mortality. Am J Kidney Dis 39:4 (2002), 834–842.
75. 75 Pun, P.H., Horton, J.R., Middleton, J.P., Dialysate calcium concentration and the risk of sudden cardiac arrest in hemodialysis patients. Clin J Am Soc Nephrol 8:5 (2013), 797–803.
76. 76 Brunelli, S.M., Sibbel, S., Do, T.P., Cooper, K., Bradbury, B.D., Facility dialysate calcium practices and clinical outcomes among patients receiving hemodialysis: a retrospective observational study. Am J Kidney Dis 66:4 (2015), 655–665.
77. 77 Kim, E.D., Parekh, R.S., Calcium and sudden cardiac death in end-stage renal disease. Semin Dial 28:6 (2015), 624–635.
78. 78 Di Lullo, L., Rivera, R., Barbera, V., et al. Sudden cardiac death and chronic kidney disease: from pathophysiology to treatment strategies. Int J Cardiol 217 (2016), 16–27.
79. 79 Flythe, J.E., Kimmel, S.E., Brunelli, S.M., Rapid fluid removal during dialysis is associated with cardiovascular morbidity and mortality. Kidney Int 79:2 (2011), 250–257.
80. 80 Mendoza, J.M., Bayes, L.Y., Sun, S., Doss, S., Schiller, B., Effect of lowering dialysate sodium concentration on interdialytic weight gain and blood pressure in patients undergoing thrice-weekly in-center nocturnal hemodialysis: a quality improvement study. Am J Kidney Dis 58:6 (2011), 956–963.
81. 81 Jefferies, H.J., Burton, J.O., McIntyre, C.W., Individualised dialysate temperature improves intradialytic haemodynamics and abrogates haemodialysis-induced myocardial stunning, without compromising tolerability. Blood Purif 32:1 (2011), 63–68.
82. 82 Odudu, A., Eldehni, M.T., McCann, G.P., McIntyre, C.W., Randomized controlled trial of individualized dialysate cooling for cardiac protection in hemodialysis patients. Clin J Am Soc Nephrol 10:8 (2015), 1408–1417.
83. 83 The FHN Trial Group. In-center hemodialysis six times per week versus three times per week. N Engl J Med 363:24 (2010), 2287–2300.
84. 84 Eckart, R.E., Gula, L.J., Reynolds, M.R., Shry, E.A., Maisel, W.H., Mortality following defibrillator implantation in patients with renal insufficiency. J Cardiovasc Electrophysiol 17:9 (2006), 940–943.
85. 85 Wase, A., Basit, A., Nazir, R., et al. Impact of chronic kidney disease upon survival among implantable cardioverter-defibrillator recipients. J Interv Card Electrophysiol 11:3 (2004), 199–204.
86. 86 Robin, J., Weinberg, K., Tiongson, J., et al. Renal dialysis as a risk factor for appropriate therapies and mortality in implantable cardioverter-defibrillator recipients. Heart Rhythm 3:10 (2006), 1196–1201.
87. 87 Sakhuja, R., Keebler, M., Lai, T.S., McLaughlin Gavin, C., Thakur, R., Bhatt, D.L., Meta-analysis of mortality in dialysis patients with an implantable cardioverter defibrillator. Am J Cardiol 103:5 (2009), 735–741.
88. 88 Dasgupta, A., Montalvo, J., Medendorp, S., et al. Increased complication rates of cardiac rhythm management devices in ESRD patients. Am J Kidney Dis 49:5 (2007), 656–663.
89. 89 Pun, P.H., Hellkamp, A.S., Sanders, G.D., et al. Primary prevention implantable cardioverter defibrillators in end-stage kidney disease patients on dialysis: a matched cohort study. Nephrol Dial Transplant 30:5 (2015), 829–835.
90. 90 Pun, P.H., Al-Khatib, S.M., Han, J.Y., et al. Implantable cardioverter-defibrillators for primary prevention of sudden cardiac death in CKD: a meta-analysis of patient-level data from 3 randomized trials. Am J Kidney Dis 64:1 (2014), 32–39.
91. 91 Drew, D.A., Meyer, K.B., Weiner, D.E., Transvenous cardiac device wires and vascular access in hemodialysis patients. Am J Kidney Dis 58:3 (2011), 494–496.
92. 92 Teruya, T.H., Abou-Zamzam, A.M. Jr., Limm, W., Wong, L., Wong, L., Symptomatic subclavian vein stenosis and occlusion in hemodialysis patients with transvenous pacemakers. Ann Vasc Surg 17:5 (2003), 526–529.
93. 93 Dhamija, R.K., Tan, H., Philbin, E., et al. Subcutaneous implantable cardioverter defibrillator for dialysis patients: a strategy to reduce central vein stenoses and infections. Am J Kidney Dis 66:1 (2015), 154–158.
94. 94 Charytan, D.M., Patrick, A.R., Liu, J., et al. Trends in the use and outcomes of implantable cardioverter-defibrillators in patients undergoing dialysis in the United States. Am J Kidney Dis 58:3 (2011), 409–417.
95. 95 Koman, E., Gupta, A., Subzposh, F., Saltzman, H., Kutalek, S.P., Outcomes of subcutaneous implantable cardioverter-defibrillator implantation in patients on hemodialysis. J Interv Card Electrophysiol 45:2 (2016), 219–223.
96. 96 El-Chami, M.F., Levy, M., Kelli, H.M., et al. Outcome of subcutaneous implantable cardioverter defibrillator implantation in patients with end-stage renal disease on dialysis. J Cardiovasc Electrophysiol 26:8 (2015), 900–904.
97. 97 National Kidney Foundation. Kidney Disease Outcomes Quality Initiative (KDOQI) Guideline 8: External Defibrillation. 2005; http://www2.kidney.org/professionals/KDOQI/guidelines_cvd/guide8.htm. Accessed August 15, 2016.
98. 98 Lehrich, R.W., Pun, P.H., Tanenbaum, N.D., Smith, S.R., Middleton, J.P., Automated external defibrillators and survival from cardiac arrest in the outpatient hemodialysis clinic. J Am Soc Nephrol 18:1 (2007), 312–320.
99. 99 Herzog, C.A., Li, S., Weinhandl, E.D., Strief, J.W., Collins, A.J., Gilbertson, D.T., Survival of dialysis patients after cardiac arrest and the impact of implantable cardioverter defibrillators. Kidney Int 68:2 (2005), 818–825.
100. 100 Hiremath, S., Punnam, S.R., Brar, S.S., et al. Implantable defibrillators improve survival in end-stage renal disease: results from a multi-center registry. Am J Nephrol 32:4 (2010), 305–310.
101. 101 Pun, P.H., The interplay between CKD, sudden cardiac death, and ventricular arrhythmias. Adv Chronic Kidney Dis 21:6 (2014), 480–488.