Rapid fluid removal during dialysis is associated with cardiovascular morbidity and mortality

Kidney International

Volumn 79, Issue 2, 2011, Pages 250-257

  Flythe, Jennifer E ^a   Kimmel, Stephen E ^b   Brunelli, Steven M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

cardiovascular death; hemodialysis; mortality; ultrafiltration

Indexed keywords

ADULT; ARTICLE; CARDIOVASCULAR RISK; CONGESTIVE HEART FAILURE; FEMALE; HAZARD RATIO; HEMODIALYSIS; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL; ULTRAFILTRATION;

EID: 78650852870     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2010.383     Document Type: Article

References (31)

1. USRDS. Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2008.
2. Foley RN, Parfrey PS, Sarnak MJ. Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis 1998; 32: S112-S119.
3. Weiner DE, Tighiouart H, Amin MG et al. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol 2004; 15: 1307-1315.
4. Shroff RC, McNair R, Figg N et al. Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis. Circulation 2008; 118: 1748-1757.
5. Pecoits-Filho R, Heimburger O, Barany P et al. Associations between circulating inflammatory markers and residual renal function in CRF patients. Am J Kidney Dis 2003; 41: 1212-1218.
6. Shoji T, Tsubakihara Y, Fujii M et al. Hemodialysis-associated hypotension as an independent risk factor for two-year mortality in hemodialysis patients. Kidney Int 2004; 66: 1212-1220.
7. John AS, Tuerff SD, Kerstein MD. Nonocclusive mesenteric infarction in hemodialysis patients. J Am Coll Surg 2000; 190: 84-88.
8. Burton JO, Jefferies HJ, Selby NM et al. Hemodialysis-induced cardiac injury: determinants and associated outcomes. Clin J Am Soc Nephrol 2009; 4: 914-920.
9. Cotter G, Felker GM, Adams KF et al. The pathophysiology of acute heart failure-is it all about fluid accumulation? Am Heart J 2008; 155: 9-18.
10. Sharpe N. Left ventricular remodeling: pathophysiology and treatment. Heart Fail Monit 2003; 4: 55-61.
11. Martin LC, Franco RJ, Gavras I et al. Association between hypervolemia and ventricular hypertrophy in hemodialysis patients. Am J Hypertens 2004; 17: 1163-1169.
12. Ritz E, Wanner C. The challenge of sudden death in dialysis patients. Clin J Am Soc Nephrol 2008; 3: 920-929.
13. Zoccali C, Benedetto FA, Tripepi G et al. Cardiac consequences of hypertension in hemodialysis patients. Semin Dial 2004; 17: 299-303.
14. Glassock RJ, Pecoits-Filho R, Barberato SH. Left ventricular mass in chronic kidney disease and ESRD. Clin J Am Soc Nephrol 2009; 4(Suppl 1): S79-S91.
15. Saran R, Bragg-Gresham JL, Levin NW et al. Longer treatment time and slower ultrafiltration in hemodialysis: associations with reduced mortality in the DOPPS. Kidney Int 2006; 69: 1222-1228.
16. Movilli E, Gaggia P, Zubani R et al. Association between high ultrafiltration rates and mortality in uraemic patients on regular haemodialysis. A 5-year prospective observational multicentre study. Nephrol Dial Transplant 2007; 22: 3547-3552.
17. Greene T, Beck GJ, Gassman JJ et al. Design and statistical issues of the Hemodialysis (HEMO) Study. Control Clin Trials 2000; 21: 502-525.
18. Lilley JJ, Golden J, Stone RA. Adrenergic regulation of blood pressure in chronic renal failure. J Clin Invest 1976; 57: 1190-1200.
19. Friess U, Rascher W, Ritz E et al. Failure of arginine-vasopressin and other pressor hormones to increase in severe recurrent dialysis hypotension. Nephrol Dial Transplant 1995; 10: 1421-1427.
20. Daul AE, Wang XL, Michel MC et al. Arterial hypotension in chronic hemodialyzed patients. Kidney Int 1987; 32: 728-735.
21. Converse RL Jr, Jacobsen TN, Jost CM et al. Paradoxical withdrawal of reflex vasoconstriction as a cause of hemodialysis-induced hypotension. J Clin Invest 1992; 90: 1657-1665.
22. Nette RW, van den Dorpel MA, Krepel HP et al. Hypotension during hemodialysis results from an impairment of arteriolar tone and left ventricular function. Clin Nephrol 2005; 63: 276-283.
23. Burton JO, Jefferies HJ, Selby NM et al. Hemodialysis-induced repetitive myocardial injury results in global and segmental reduction in systolic cardiac function. Clin J Am Soc Nephrol 2009; 4: 1925-1931.
24. Selby NM, Burton JO, Chesterton LJ et al. Dialysis-induced regional left ventricular dysfunction is ameliorated by cooling the dialysate. Clin J Am Soc Nephrol 2006; 1: 1216-1225.
25. Selby NM, Lambie SH, Camici PG et al. Occurrence of regional left ventricular dysfunction in patients undergoing standard and biofeedback dialysis. Am J Kidney Dis 2006; 47: 830-841.
26. Shivalkar B, Flameng W, Szilard M et al. Repeated stunning precedes myocardial hibernation in progressive multiple coronary artery obstruction. J Am Coll Cardiol 1999; 34: 2126-2136.
27. Sharp J, Wild MR, Gumley AI et al. A cognitive behavioral group approach to enhance adherence to hemodialysis fluid restrictions: a randomized controlled trial. Am J Kidney Dis 2005; 45: 1046-1057.
28. Bame SI, Petersen N, Wray NP. Variation in hemodialysis patient compliance according to demographic characteristics. Soc Sci Med 1993; 37: 1035-1043.
29. Suri RS, Garg AX, Chertow GM et al. Frequent Hemodialysis Network (FHN) randomized trials: study design. Kidney Int 2007; 71: 349-359.
30. Gura V, Macy AS, Beizai M et al. Technical breakthroughs in the wearable artificial kidney (WAK). Clin J Am Soc Nephrol 2009; 4: 1441-1448.
31. Eknoyan G, Beck GJ, Cheung AK et al. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med 2002; 347: 2010-2019.