Imaging leukocyte responses in the kidney

Transplantation

Volumn 101, Issue 3, 2017, Pages 506-516

  Finsterbusch, Michaela ^a   Kitching, A Richard ^a   Hickey, Michael J ^a  

^a MONASH MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE KIDNEY FAILURE; ANTIGEN PRESENTING CELL; APOPTOSIS; B LYMPHOCYTE; CELL DEATH; DENDRITIC CELL; ENDOTHELIUM CELL; GLOMERULONEPHRITIS; GLOMERULUS CAPILLARY; HUMAN; IMMUNOCOMPETENT CELL; INFLAMMATION; INTRAVITAL MICROSCOPY; KIDNEY; KIDNEY ALLOGRAFT; KIDNEY INTERSTITIUM; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; LEUKOCYTE FUNCTION; LEUKOCYTE RECRUITMENT; MACROPHAGE; MICROVASCULATURE; MONOCYTE; NEUTROPHIL; NONHUMAN; PODOCYTE; PYELONEPHRITIS; REPERFUSION INJURY; REVIEW; SEPSIS; STEADY STATE; T LYMPHOCYTE; THROMBOCYTE; URETER OBSTRUCTION; ANIMAL; CONFOCAL MICROSCOPY; IMMUNOLOGY; KIDNEY DISEASES; LEUKOCYTE; METABOLISM; MOLECULAR IMAGING; MULTIPHOTON MICROSCOPY; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PROCEDURES;

BIOLOGICAL MARKER;

ANIMALS; BIOMARKERS; CHEMOTAXIS, LEUKOCYTE; HUMANS; INTRAVITAL MICROSCOPY; KIDNEY; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; LEUKOCYTES; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MOLECULAR IMAGING;

EID: 85012877537     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000001557     Document Type: Review

References (67)

1. Ley K, Laudanna C, Cybulsky MI, et al. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol. 2007;7: 678-689.
2. Kolaczkowska E, Kubes P. Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol. 2013;13:159-175.
3. Sumen C,Mempel TR, Mazo IB, et al. Intravitalmicroscopy: visualizing immunity in context. Immunity. 2004;21:315-329.
4. Hickey MJ, Kubes P. Intravascular immunity: the host-pathogen encounter in blood vessels. Nat Rev Immunol. 2009;9:364-375.
5. Rossaint J, Zarbock A. Tissue-specific neutrophil recruitment into the lung, liver, and kidney. J Innate Immun. 2013;5:348-357.
6. Hickey MJ,Westhorpe CL. Imaging inflammatory leukocyte recruitment in kidney, lung and liver-challenges to the multi-step paradigm. Immunol Cell Biol. 2013;91:281-289.
7. Kitching AR, Holdsworth SR, Hickey MJ. Targeting leukocytes in immune glomerular diseases. Curr Med Chem. 2008;15:448-458.
8. Vielhauer V, Kulkarni O, Reichel CA, et al. Targeting the recruitment of monocytes and macrophages in renal disease. Semin Nephrol. 2010; 30:318-333.
9. Devi S, Li A,Westhorpe CLV, et al. Multiphoton imaging reveals a new leukocyte recruitment paradigm in the glomerulus. Nat Med. 2013;19: 107-112.
10. Block H, Herter JM, Rossaint J, et al. Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury. J Exp Med. 2012;209:407-421.
11. Finsterbusch M, Hall P, Li A, et al. Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely-inflamed glomerulus. Proc Natl Acad Sci U S A. 2016;113:E5172-E5181.
12. Soos TJ, Sims TN, Barisoni L, et al. CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney. Kidney Int. 2006;70:591-596.
13. Snelgrove SL, Kausman JY, Lo C, et al. Renal dendritic cells adopt a proinflammatory phenotype in obstructive uropathy to activate T cells but do not directly contribute to fibrosis. Am J Pathol. 2012;180:91-103.
14. Snelgrove SL, Lo C, Hall P, et al. Activated renal dendritic cells cross present intrarenal antigens after ischemia reperfusion injury. [published online August 5, 2016] Transplantation. DOI: 10. 1097/TP. 0000000000001427.
15. Yatim KM, Gosto M, Humar R, et al. Renal dendritic cells sample bloodborne antigen and guide T-cell migration to the kidney by means of intravascular processes. Kidney Int. 2016;90:818-827.
16. Zhuang Q, Liu Q, Divito SJ, et al. Graft-infiltrating host dendritic cells play a key role in organ transplant rejection. Nat Commun. 2016;7:12623.
17. Chousterman BG, Boissonnas A, Poupel L, et al. Ly6Chigh monocytes protect against kidney damage during sepsis via a CX3CR1-dependent adhesion mechanism. J Am Soc Nephrol. 2016;27:792-803.
18. Sutton TA, Mang HE, Campos SB, et al. Injury of the renal microvascular endothelium alters barrier function after ischemia. Am J Physiol Renal Physiol. 2003;285:F191-F198.
19. Hackl MJ, Burford JL, Villanueva K, et al. Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags. Nat Med. 2013;19:1661-1666.
20. Kuligowski MP, Kitching AR, Hickey MJ. Leukocyte recruitment to the inflamed glomerulus: a critical role for platelet-derived P-selectin in the absence of rolling. J Immunol. 2006;176:6991-6999.
21. Imamura R, Isaka Y, Sandoval RM, et al. Intravital two-photonmicroscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models. Cell Transplant. 2010;19:1659-1670.
22. Devi S, Kuligowski MP, Kwan RY, et al. Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway. Am J Pathol. 2010;177:1131-1142.
23. Sharfuddin AA, Sandoval RM, Berg DT, et al. Soluble thrombomodulin protects ischemic kidneys. J Am Soc Nephrol. 2009;20:524-534.
24. Camirand G, Li Q, Demetris AJ, et al. Multiphoton intravital microscopy of the transplanted mouse kidney. Am J Transplant. 2011;11:2067-2074.
25. Engel DR, Krause TA, Snelgrove SL, et al. CX3CR1 reduces kidney fibrosis by inhibiting local proliferation of profibrotic macrophages. J Immunol. 2015;194:1628-1638.
26. Walch JM, Zeng Q, Li Q, et al. Cognate antigen directs CD8+ Tcell migration to vascularized transplants. J Clin Invest. 2013;123:2663-2671.
27. Hato T, Winfree S, Kalakeche R, et al. The macrophage mediates the renoprotective effects of endotoxin preconditioning. J Am Soc Nephrol. 2015;26:1347-1362.
28. Gupta A, Rhodes GJ, Berg DT, et al. Activated protein C ameliorates LPSinduced acute kidney injury and downregulates renal INOS and angiotensin 2. Am J Physiol Renal Physiol. 2007;293:F245-F254.
29. Bedke J, Kiss E, Behnes CL, et al. Anti-inflammatory effects of alphav integrin antagonism in acute kidney allograft rejection. Am J Pathol. 2007;171:1127-1139.
30. Carlin LM, Stamatiades EG, Auffray C, et al. Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal. Cell. 2013;153:362-375.
31. Oberbarnscheidt MH, Zeng Q, Li Q, et al. Non-self recognition by monocytes initiates allograft rejection. J Clin Invest. 2014;124:3579-3589.
32. Herter JM, Rossaint J, Block H, et al. Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling. Blood. 2013;121:2301-2310.
33. Herter JM, Rossaint J, Spieker T, et al. Adhesion molecules involved in neutrophil recruitment during sepsis-induced acute kidney injury. J Innate Immun. 2014;6:597-606.
34. KuligowskiMP, Kwan RY, Lo C, et al. Antimyeloperoxidase antibodies rapidly induce alpha-4-integrin-dependent glomerular neutrophil adhesion. Blood. 2009;113:6485-6494.
35. Kaissling B, Le Hir M. Characterization and distribution of interstitial cell types in the renal cortex of rats. Kidney Int. 1994;45:709-720.
36. Kruger T, Benke D, Eitner F, et al. Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis. J Am Soc Nephrol. 2004;15:613-621.
37. Kawakami T, Lichtnekert J, Thompson LJ, et al. Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions. J Immunol. 2013;191:3358-3372.
38. Auffray C, Fogg D, Garfa M, et al. Monitoring of blood vessels and tissues by a population ofmonocytes with patrolling behavior. Science. 2007;317: 666-670.
39. Li W, Nava RG, Bribriesco AC, et al. Intravital 2-photon imaging of leukocyte trafficking in beating heart. J Clin Invest. 2012;122:2499-2508.
40. Sumagin R, Prizant H, Lomakina E, et al. LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ. J Immunol. 2010;185:7057-7066.
41. Steinert EM, Schenkel JM, Fraser KA, et al. Quantifying memory CD8 T cells reveals regionalization of immunosurveillance. Cell. 2015;161: 737-749.
42. Dunn KW, Sandoval RM, Kelly KJ, et al. Functional studies of the kidney of living animals using multicolor two-photon microscopy. Am J Physiol Cell Physiol. 2002;283:C905-C916.
43. Dunn KW, Sutton TA, Sandoval RM. Live-animal imaging of renal function by multiphoton microscopy. Curr Protoc Cytom. 2012;Chapter 14: Unit12 9.
44. Peti-Peterdi J, Kidokoro K, Riquier-Brison A. Novel in vivo techniques to visualize kidney anatomy and function. Kidney Int. 2015;88:44-51.
45. Steinhausen M, Snoei H, Parekh N, et al. Hydronephrosis: a new method to visualize vas afferens, efferens, and glomerular network. Kidney Int. 1983;23:794-806.
46. Bührle CP, Hackenthal E, Helmchen U, et al. The hydronephrotic kidney of the mouse as a tool for intravital microscopy and in vitro electrophysiological studies of renin-containing cells. Lab Invest. 1986;54:462-472.
47. Molitoris BA. Therapeutic translation in acute kidney injury: the epithelial/ endothelial axis. J Clin Invest. 2014;124:2355-2363.
48. Bonventre JV, Weinberg JM. Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol. 2003;14:2199-2210.
49. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med. 1996;334:1448-1460.
50. Rabb H, Mendiola CC, Dietz J, et al. Role of CD11a and CD11b in ischemic acute renal failure in rats. Am J Physiol. 1994;267:F1052-F1058.
51. Kelly KJ, Williams WW Jr, Colvin RB, et al. Antibody to intercellular adhesion molecule 1 protects the kidney against ischemic injury. Proc Natl Acad Sci U S A. 1994;91:812-816.
52. Kelly KJ,WilliamsWWJr, Colvin RB, et al. Intercellular adhesionmolecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest. 1996;97:1056-1063.
53. Singbartl K, Ley K. Protection from ischemia-reperfusion induced severe acute renal failure by blocking E-selectin. Crit Care Med. 2000;28: 2507-2514.
54. Singbartl K, Green SA, Ley K. Blocking P-selectin protects fromischemia/ reperfusion-induced acute renal failure. FASEB J. 2000;14:48-54.
55. Singbartl K, Forlow SB, Ley K. Platelet, but not endothelial, P-selectin is critical for neutrophil-mediated acute postischemic renal failure. FASEB J. 2001;15:2337-2344.
56. Basile DP, Friedrich JL, Spahic J, et al. Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury. Am J Physiol Renal Physiol. 2011;300:F721-F733.
57. Hall AM, Rhodes GJ, Sandoval RM, et al. In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury. Kidney Int. 2013;83:72-83.
58. LeMoine A, GoldmanM, Abramowicz D. Multiple pathways to allograft rejection. Transplantation. 2002;73:1373-1381.
59. Månsson LE, Melican K, Boekel J, et al. Real-time studies of the progression of bacterial infections and immediate tissue responses in live animals. Cell Microbiol. 2007;9:413-424.
60. Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315:801-810.
61. Sauter KA, Pridans C, Sehgal A, et al. The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration. PLoS One. 2014;9:e105429.
62. El-Achkar TM, Huang X, Plotkin Z, et al. Sepsis induces changes in the expression and distribution of Toll-like receptor 4 in the rat kidney. Am J Physiol Renal Physiol. 2006;290:F1034-F1043.
63. Kalakeche R, Hato T, Rhodes G, et al. Endotoxin uptake by S1 proximal tubular segment causes oxidative stress in the downstream S2 segment. J Am Soc Nephrol. 2011;22:1505-1516.
64. Ma FY, Liu J, Kitching AR, et al. Targeting renalmacrophage accumulation via c-fms kinase reduces tubular apoptosis but fails tomodify progressive fibrosis in the obstructed rat kidney. Am J Physiol Renal Physiol. 2009; 296:F177-F185.
65. Edgtton KL, Gow RM, Kelly DJ, et al. Plasmin is not protective in experimental renal interstitial fibrosis. Kidney Int. 2004;66:68-76.
66. Kitching AR, Hutton HL. The players: cells involved in glomerular disease. Clin J Am Soc Nephrol. 2016;11:1664-1674.
67. Jarrot PA, Kaplanski G. Pathogenesis of ANCA-associated vasculitis: an update. Autoimmun Rev. 2016;15:704-713.