Blocking P-selectin protects from ischemia/reperfusion-induced acute renal failure

FASEB Journal

Volumn 14, Issue 1, 2000, Pages 48-54

  Singbartl, Kai ^a,c   Green, Samuel A ^b   Klaus, Ley ^a  

^a University of Virginia School of Medicine   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Adhesion molecules; Antibodies; Gene targeting; Neutrophils; Renal function

Indexed keywords

PADGEM PROTEIN;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ARTICLE; CELL INFILTRATION; KIDNEY BLOOD FLOW; KIDNEY ISCHEMIA; MOUSE; NEUTROPHIL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ANIMALIA;

EID: 0033963076     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.14.1.48     Document Type: Article

References (45)

1. Tetta, C., Montrucchio, G., Ronco C., and Capen, R. L. (1995) Mechanisms of tissue damage in acute renal failure. In Acute Renal Failure in the Critically Ill (Bellomo, R., and Ronco, C., eds) pp. 64-89, Springer-Verlag, Berlin-Heidelberg
2. Müller, J. M., Vollmar, B., and Menger, M. D. (1997) Pentoxifylline reduces venular leukocyte adherence ('reflow paradox') but not microvascular 'no reflow' in hepatic ischemia/reperfusion. J. Surg. Res. 71, 1-6
3. Rabb, H., and Postler, G. (1998) Leukocyte adhesion molecules in ischaemic renal injury: kidney specific paradigms? Clin. Exp. Pharm. Physiol. 25, 286-291
4. Mason, J., Joeris, B., Welsch, J., and Kriz, W. (1989) Vascular congestion in ischemic renal failure: the role of cell swelling. Miner. Electrolyte. Metab. 15, 114-124
5. Menger, M. D., and Vollmar, B. (1994) In vivo analysis of microvascular reperfusion injury in striated muscle and skin. Microsurgery 15, 383-389
6. Kelly, K. J., Williams, W. W. J., Colvin, R. B., Meehan, S. M., Springer, T. A., Gutierrez-Ramos, J. C., and Bonventre, J. V. (1996) Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J. Clin. Invest. 97, 1056-1063
7. Rabb, H., Mendiola, C. C., Saba, S. R., Dietz, J. R., Smith, C. W., Bonventre, J. V., and Ramirez, G. (1995) Antibodies to ICAM-1 protect kidneys in severe ischemic reperfusion injury. Biochem. Biophys. Res. Commun. 211, 67-73
8. Kelly, K. J., Williams, W. W. J., Colvin, R. B., Bonventre, J. V. (1994) Antibody to intercellular adhesion molecule 1 protects the kidney against ischemic injury. Proc. Natl. Acad. Sci. USA 91, 812-816
9. Rabb, H., Ramirez, G., Saba, S. R., Reynolds, D., Xu, J., Flavell, R., and Antonia, S. (1996) Renal ischemic-reperfusion injury in L-selectin-deficient mice. Am. J. Physiol. 271, F408-F413
10. Linas, S., Whittenburg, D., and Repine, J. E. (1997) Nitric oxide prevents neutrophil-mediated acute renal failure. Am. J. Physiol. 272, F48-F54
11. Linas, S. L., Whittenburg, D., Parsons, P. E., and Repine, J. E. (1995) Ischemia increases neutrophil retention and worsens acute renal failure: role of oxygen metabolites and ICAM 1. Kidney Int. 48, 1584-1591
12. Butcher, E. C. (1991) Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67, 1033-1036
13. Springer, T. A. (1995) Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu. Rev. Physiol. 57, 827-872
14. Kansas, G. S. (1996) Selectins and their ligands: current concepts and controversies. Blood 88, 3259-3287
15. Vestweber, D., and Blanks, J. E. (1999) Mechanisms that regulate the function of the selectins and their ligands. Physiol. Rev. 79, 181-213
16. Jung, U., Norman, K. E., Scharffetter-Kochanek, K., Beaudet, A. L., and Ley, K. (1998) Transit time of leukocytes rolling through venule controls cytokine-induced inflammatory cell recruitment in vivo. J. Clin. Invest. 102 (8), 1526-1533
17. Rabb, H., Mendiola, C. C., Dietz, J., Saba, S. R., Issekutz, T. B., Abanilla, F., Bonventre, J. V., and Ramirez, G. (1994) Role of CD11a and CD11b in ischemic acute renal failure in rats. Am. J. Physiol. 267, F1052-F1058
18. Thornton, M. A., Winn, R., Alpers, C. E., and Zager, R. A. (1989) An evaluation of the neutrophil as a mediator of in vivo renal ischemic-reperfusion injury. Am. J. Pathol. 135, 509-515
19. Haller, H., Dragun, D., Miethke, A., Park, J. K., Weis, A., Lippoldt, A., Gross, V., and Luft, F. C. (1996) Antisense oligonucleotides for ICAM-1 attenuate reperfusion injury and renal failure in the rat. Kidney Int. 50, 473-480
20. Zizzi, H. C., Zibari, G. B., Granger, D. N., Singh, I., Cruz, L. D., Abreo, F., Mcdonald, J. C., and Brown, M. F. (1997) Quantification of P-selectin expression after renal ischemia and reperfusion. J. Ped. Surg. 32, 1010-1013
21. Geng, J. G., Bevilacqua, M. P., Moore, K. L., McIntyre, T. M., Prescott, S. M., Kim, J. M., Bliss, G. A., Zimmerman, G. A., and McEver, R. P. (1990) Rapid neutrophil adhesion to activated endothelium mediated by GMP-140. Nature (London) 343, 757-760
22. McEver, R. P., Beckstead, J. H., Moore, K. L., Marshall-Carlson, L., and Bainton, D. F. (1989) GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J. Clin. Invest 84, 92-99
23. Berman, C. L., Yeo, E. L., Wencel-Drake, J. D., Furie, B. C., Ginsberg, M. H., and Furie, B. (1986) A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein. J. Clin. Invest. 78, 130-137
24. Foreman, K. E., Vaporciyan, A. A., Bonish, B. K., Jones, M. L., Johnson, K. J, Glovsky, M. M., Eddy, S. M., and Ward, P. A. (1994) C5a-induced expression of P-selectin in endothelial cells. J. Clin. Invest. 94, 1147-1155
25. Sanders, W. E., Wilson, R. W., Ballantyne, C. M., and Beaudet, A. L. (1992) Molecular cloning and analysis of in vivo expression of murine P-selectin. Blood 80, 795-800
26. Bullard, D. C., Kunkel, E. J., Kubo, H., Hicks, M. J., Lorenzo, I., Doyle, N. A., Doerschuk, C. M., Ley, K., and Beaudet, A. L. (1996) Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J. Exp. Med. 183, 2329-2336
27. Racusen, L. C., Trpkov, K., and Solez, K. (1995) Pathology of acute renal failure. In Acute Renal Failure in the Critically Ill (Bellomo, R., and Ronco, C., eds) pp. 1-27, Springer Verlag, Berlin
28. Bosse, R., and Vestweber, D. (1994) Only simultaneous blocking of the L-and P-selectin completely inhibits neutrophil migration into mouse peritoneum. Eur. J. Immunol. 24, 3019-3024
29. Grisham, M. B., Hernandez, L. A., and Granger, D. N. (1986) Xanthine oxidase and neutrophil infiltration in intestinal ischemia. Am. J. Physiol. 251, G567-G574
30. Hillegass, L. M., Griswold, D. E., Brickson, B., and Albrightson-Winslow, C. (1990) Assessment of myeloperoxidase activity in whole rat kidney. J. Pharmacol. Methods 24, 285-295
31. Green, S. A., Setiadi, H., McEver, R. P., and Kelly, R. B. (1994) The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes. J. Cell Biol. 124, 435-448
32. Hellberg, P. O., Kallskog, O. T., Ojteg, G., and Wolgast, M. (1990) Peritubular capillary permeability and intravascular RBC aggregation after ischemia: effects of neutrophils. Am. J. Physiol. 258, F1018-F1025
33. Hellberg, P. O., and Kallskog, T. O. (1989) Neutrophil-mediated post-ischemic tubular leakage in the rat kidney. Kidney Int. 36, 555-561
34. Klausner, J. M., Paterson, I. S., Goldman, G., Kobzik, L., Rodzen, C., Lawrence, R., Valeri, C. R., Shepro, D., and Hechtman, H. B. (1989) Postischemic renal injury is mediated by neutrophils and leukotrienes. Am. J. Physiol. 256, F794-F802
35. Paller, M. S. (1989) Effect of neutrophil depletion on ischemic renal injury in the rat. J. Lab. Clin. Med. 113, 379-386
36. Johnson, J. P., and Rokaw, M. D. (1995) Experimental acute renal failure. In Acute Renal Failure in the Critically Ill (Bellomo, R., and Ronco, C., eds) pp. 28-57, Springer Verlag, Berlin
37. Koo, D. D. H., Welsh, K. I., Roake, J. A., Morris, P. J., and Fuggle, S. V. (1998) Ischemia/reperfusion injury in human kidney transplantation - an immunhistochemical analysis of changes after reperfusion. Am. J. Pathol. 153, 557-566
38. 2-integrin CD11b/CD18. Blood 88, 146-157
39. Brezis, M., and Rosen, S. (1995) Hypoxia of the renal medulla -its implications for disease. N. Engl. J. Med. 332, 647-655
40. Lefer, D. J., Flynn, D. M., and Buda, A. J. (1996) Effects of a monoclonal antibody directed against P-selectin after myocardial ischemia and reperfusion. Am. J. Physiol. 39, H88-H98
41. Ohnishi, M., Yamada, K., Morooka, S., and Tojo, S. J. (1999) Inhibition of P-selectin attenuates neutrophil-mediated myocardial dysfunction in isolated rat heart. Eur. J. Pharmacol. 366, 271-279
42. Goussev, A. V., Zhang, Z. G., Anderson, D. C., and Chopp, M. (1998) P-selectin antibody reduces hemorrhage and infarct volume resulting from MCA occlusion in the rat. J. Neurol. Sci. 161, 16-22
43. Connolly, E. S., Winfree, C. J., Prestigiacomo, C. J., Kim, S. C., Choudhri, T. F., Hoh, B. L., Naka, Y., Solomon, R. A., and Pinsky, D. J. (1997) Exacerbation of cerebral injury in mice that express the P-selectin gene - identification of P-selectin blockade as a new target for the treatment of stroke. Circ. Res. 81, 304-310
44. Singh, I., Zibari, G. B., Zizzi, H., Granger, D. N., Cruz, L., Gonsales, E., McDonald, J. C., and Brown, M. F. (1998) Anti-P-selectin antibody protects against hepatic ischemia-reperfusion injury. Transpl. Proc. 30, 2324-2326
45. Takada, M., Nadeau, K. C., Shaw, G. D., Marquette, K. A., and Tilney, N. L. (1997) The cytokine-adhesion molecule cascade in ischemia/reperfusion injury of the rat kidney. Inhibition by a soluble P-selectin ligand. J. Clin. Invest. 99, 2682-2690