Synthetic metabolic bypass for a metabolic toggle switch enhances acetyl-CoA supply for isopropanol production by Escherichia coli

Journal of Bioscience and Bioengineering

Volumn 123, Issue 5, 2017, Pages 625-633

  Soma, Yuki ^a,c   Yamaji, Taiki ^a   Matsuda, Fumio ^b   Hanai, Taizo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Acetyl CoA supply; Biosynthetic pathway; Metabolic toggle switch; Synthetic genetic circuit; Synthetic metabolic bypass

Indexed keywords

CELL GROWTH; ESCHERICHIA COLI; GLUCOSE; GROWTH KINETICS; METABOLITES;

ACETYL-COA; BIOSYNTHETIC PATHWAY; GENETIC CIRCUITS; SYNTHETIC METABOLIC BYPASS; TOGGLE SWITCH;

METABOLISM;

2 PROPANOL; ACETYL COENZYME A; PYRUVIC ACID DERIVATIVE; ESCHERICHIA COLI PROTEIN; GLUCOSE; PYRUVIC ACID;

ALCOHOL PRODUCTION; ARTICLE; BACTERIAL GROWTH; BIOSYNTHESIS; CITRIC ACID CYCLE; CONTROLLED STUDY; ESCHERICHIA COLI; NONHUMAN; GENETICS; GLYCOLYSIS; GROWTH, DEVELOPMENT AND AGING; METABOLIC ENGINEERING; METABOLIC FLUX ANALYSIS; METABOLISM; SUPPLY AND DISTRIBUTION;

2-PROPANOL; ACETYL COENZYME A; BIOSYNTHETIC PATHWAYS; CITRIC ACID CYCLE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLUCOSE; GLYCOLYSIS; METABOLIC ENGINEERING; METABOLIC FLUX ANALYSIS; PYRUVIC ACID;

EID: 85012874128     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2016.12.009     Document Type: Article

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