Enforced ATP futile cycling increases specific productivity and yield of anaerobic lactate production in Escherichia coli

Biotechnology and Bioengineering

Volumn 112, Issue 10, 2015, Pages 2195-2199

  Hädicke, Oliver ^a   Bettenbrock, Katja ^a   Klamt, Steffen ^a  

^a MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

Author keywords

ATP futile cycling; Cofactor engineering; Lactate; Metabolic engineering; Product yield; Productivity

Indexed keywords

ECONOMIC AND SOCIAL EFFECTS; ESCHERICHIA COLI; LACTIC ACID; METABOLISM; PRODUCT DESIGN; PRODUCTIVITY; SUBSTRATES;

ANAEROBIC CONDITIONS; BIOTECHNOLOGICAL PROCESS; COFACTOR ENGINEERING; LACTATE; PRODUCT YIELDS; SPECIFIC PRODUCTION RATE; SPECIFIC PRODUCTIVITY; VOLUMETRIC PRODUCTIVITY;

METABOLIC ENGINEERING;

ADENOSINE TRIPHOSPHATE; GLUCOSE; LACTIC ACID; PHOSPHOENOLPYRUVATE; PYRUVATE KINASE;

ADENOSINE TRIPHOSPHATE FUTILE CYCLING; ANAEROBIC FERMENTATION; ANAEROBIC GROWTH; ARTICLE; BACTERIAL GROWTH; CYANOBACTERIUM; ESCHERICHIA COLI; GLUCOSE INTAKE; METABOLIC ENGINEERING; MICROBIAL BIOMASS; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN EXPRESSION; CITRIC ACID CYCLE; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROCEDURES;

ESCHERICHIA COLI;

ADENOSINE TRIPHOSPHATE; ANAEROBIOSIS; ESCHERICHIA COLI; GENE DELETION; LACTIC ACID; METABOLIC ENGINEERING; MUTAGENESIS, INSERTIONAL; SUBSTRATE CYCLING;

EID: 84940467061     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25623     Document Type: Article

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