Ulinastatin downregulates TLR4 and NF-kB expression and protects mouse brains against ischemia/reperfusion injury

Neurological Research

Volumn 39, Issue 4, 2017, Pages 367-373

  Li, Xiaofang ^a   Su, Likai ^a   Zhang, Xiangjian ^b   Zhang, Cong ^b   Wang, Lina ^b   Li, Yaoru ^b   Zhang, Ye ^b   He, Tingting ^b   Zhu, Xingyuan ^b   Cui, Lili ^b  

^a HEBEI UNIVERSITY   (China)

^b HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral ischemia reperfusion; inflammatory; nuclear factor kappa B; toll like receptor 4; ulinastatin

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 4; ULINASTATIN; GLYCOPROTEIN; MESSENGER RNA; NEUROPROTECTIVE AGENT; TLR4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN WATER; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NEUROLOGIC DISEASE ASSESSMENT; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BRAIN; DISEASE MODEL; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; PATHOLOGY; PRECLINICAL STUDY; RANDOMIZATION;

ANIMALS; BRAIN; BRAIN EDEMA; DISEASE MODELS, ANIMAL; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; GLYCOPROTEINS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; RANDOM ALLOCATION; REPERFUSION INJURY; RNA, MESSENGER; TOLL-LIKE RECEPTOR 4;

EID: 85012278878     PISSN: 01616412     EISSN: 17431328     Source Type: Journal    
DOI: 10.1080/01616412.2017.1286541     Document Type: Article

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