Ulinastatin attenuates experimental autoimmune encephalomyelitis by enhancing anti-inflammatory responses

Neurochemistry International

Volumn 64, Issue 1, 2014, Pages 64-72

  Feng, Ming ^a,b   Shu, Yaqing ^a   Yang, Yu ^a   Zheng, Xueping ^c   Li, Rui ^a   Wang, Yuge ^a   Dai, Yongqiang ^a   Qiu, Wei ^a   Lu, Zhengqi ^a   Hu, Xueqiang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^c QINGDAO UNIVERSITY   (China)

Author keywords

Experimental autoimmune encephalomyelitis; Inflammatory responses; Ulinastatin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GAMMA INTERFERON; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN; UNCLASSIFIED DRUG; UTI;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; ATTENUATION; COGNITION; CONTROLLED STUDY; DEMYELINATION; DOWN REGULATION; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SPINAL CORD; UPREGULATION;

ANIMALIA; MUS;

BDNF; BRAIN-DERIVED NEUROTROPHIC FACTOR; CENTRAL NERVOUS SYSTEM; CNS; EAE; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; HE; HEMATOXYLIN AND EOSIN; IF; IFN-Γ; IMMUNOFLUORESCENCE; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLAMMATORY RESPONSES; INOS; INTERFERON-Γ; LFB; LUXOL FAST BLUE; MACROPHAGE INFLAMMATORY PROTEIN-2; MATRIX METALLOPROTEINASE-9; MCP-1; MIP-2; MMP-9; MONOCYTE CHEMOTACTIC PROTEIN-1; MS; MULTIPLE SCLEROSIS; NERVE GROWTH FACTOR; NF-ΚB; NGF; NUCLEAR FACTOR KAPPAB; RANTES; REGULATED UPON ACTIVATION NORMAL T CELL EXPRESSED AND PRESUMABLY SECRETED; SICAM-1; SOLUBLE INTERCELLULAR ADHESION MOLECULE-1; TNF-Α; TUMOR NECROSIS FACTOR-ALPHA; ULINASTATIN; UTI;

ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GLYCOPROTEINS; INFLAMMATION; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MYELIN BASIC PROTEIN; SPINAL CORD; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84888806408     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.11.007     Document Type: Article

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