메뉴 건너뛰기




Volumn 44, Issue 22, 2016, Pages 10603-10618

A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; METHYLTRANSFERASE; MICRORNA; MICRORNA 24 2; MICRORNA 24 2 5P; MICRORNA 24 3P; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN ARGININE METHYLTRANSFERASE 7; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; KRUPPEL LIKE FACTOR; MIRN24 MICRORNA, MOUSE; MYC PROTEIN, MOUSE; NANOG PROTEIN, MOUSE; POU5F1 PROTEIN, MOUSE; PRMT7 PROTEIN, MOUSE; PROTEIN ARGININE METHYLTRANSFERASE;

EID: 85012196734     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw788     Document Type: Article
Times cited : (57)

References (54)
  • 1
    • 79958252915 scopus 로고    scopus 로고
    • Chromatin connections to pluripotency and cellular reprogramming
    • Orkin, S.H. and Hochedlinger, K. (2011) Chromatin connections to pluripotency and cellular reprogramming. Cell, 145, 835-850.
    • (2011) Cell , vol.145 , pp. 835-850
    • Orkin, S.H.1    Hochedlinger, K.2
  • 2
    • 77957970498 scopus 로고    scopus 로고
    • Epigenetic modifications in pluripotent and differentiated cells
    • Meissner, A. (2010) Epigenetic modifications in pluripotent and differentiated cells. Nat. Biotechnol., 28, 1079-1088.
    • (2010) Nat. Biotechnol , vol.28 , pp. 1079-1088
    • Meissner, A.1
  • 3
    • 33947301272 scopus 로고    scopus 로고
    • Epigenetic signatures of stem-cell identity
    • Spivakov, M. and Fisher, A.G. (2007) Epigenetic signatures of stem-cell identity. Nat. Rev. Genet., 8, 263-271.
    • (2007) Nat. Rev. Genet , vol.8 , pp. 263-271
    • Spivakov, M.1    Fisher, A.G.2
  • 4
    • 84885128137 scopus 로고    scopus 로고
    • Histone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells
    • Gu, B. and Lee, M.G. (2013) Histone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells. Cell Biosci., 3, 39-53.
    • (2013) Cell Biosci , vol.3 , pp. 39-53
    • Gu, B.1    Lee, M.G.2
  • 5
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein, T. and Allis, C.D. (2001) Translating the histone code. Science, 293, 1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 6
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl, B.D. and Allis, C.D. (2000) The language of covalent histone modifications. Nature, 403, 41-45.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 7
    • 0036532026 scopus 로고    scopus 로고
    • Histone modifications in transcriptional regulation
    • Berger, S.L. (2002) Histone modifications in transcriptional regulation. Curr. Opin. Genet. Dev., 12, 142-148.
    • (2002) Curr. Opin. Genet. Dev , vol.12 , pp. 142-148
    • Berger, S.L.1
  • 8
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • Li, B., Carey, M. and Workman, J.L. (2007) The role of chromatin during transcription. Cell, 128, 707-719.
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 9
    • 58149295717 scopus 로고    scopus 로고
    • Protein arginine methylation in mammals: Who, what, and why
    • Bedford, M.T. and Clarke, S.G. (2009) Protein arginine methylation in mammals: who, what, and why. Mol. Cell, 33, 1-13.
    • (2009) Mol. Cell , vol.33 , pp. 1-13
    • Bedford, M.T.1    Clarke, S.G.2
  • 10
    • 84904048466 scopus 로고    scopus 로고
    • Readers of histone methylarginine marks
    • Gayatri, S. and Bedford, M.T. (2014) Readers of histone methylarginine marks. Biochim. Biophys. Acta, 1839, 702-710.
    • (2014) Biochim. Biophys. Acta , vol.1839 , pp. 702-710
    • Gayatri, S.1    Bedford, M.T.2
  • 12
    • 70350686165 scopus 로고    scopus 로고
    • Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
    • Yuan, P., Han, J., Guo, G., Orlov, Y.L., Huss, M., Loh, Y.H., Yaw, L.P., Robson, P., Lim, B. and Ng, H.H. (2009) Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev., 23, 2507-2520.
    • (2009) Genes Dev , vol.23 , pp. 2507-2520
    • Yuan, P.1    Han, J.2    Guo, G.3    Orlov, Y.L.4    Huss, M.5    Loh, Y.H.6    Yaw, L.P.7    Robson, P.8    Lim, B.9    Ng, H.H.10
  • 13
    • 78650212707 scopus 로고    scopus 로고
    • Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency
    • Tee, W.W., Pardo, M., Theunissen, T.W., Yu, L., Choudhary, J.S., Hajkova, P. and Surani, M.A. (2010) Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency. Genes Dev., 24, 2772-2777.
    • (2010) Genes Dev , vol.24 , pp. 2772-2777
    • Tee, W.W.1    Pardo, M.2    Theunissen, T.W.3    Yu, L.4    Choudhary, J.S.5    Hajkova, P.6    Surani, M.A.7
  • 14
    • 33846226977 scopus 로고    scopus 로고
    • Histone arginine methylation regulates pluripotency in the early mouse embryo
    • Torres-Padilla, M.E., Parfitt, D.E., Kouzarides, T. and Zernicka-Goetz, M. (2007) Histone arginine methylation regulates pluripotency in the early mouse embryo. Nature, 445, 214-218.
    • (2007) Nature , vol.445 , pp. 214-218
    • Torres-Padilla, M.E.1    Parfitt, D.E.2    Kouzarides, T.3    Zernicka-Goetz, M.4
  • 15
    • 84872495808 scopus 로고    scopus 로고
    • Pivots of pluripotency: The roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells
    • Huo, J.S. and Zambidis, E.T. (2013) Pivots of pluripotency: The roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells. Biochim. Biophys. Acta, 1830, 2385-2394.
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 2385-2394
    • Huo, J.S.1    Zambidis, E.T.2
  • 17
    • 84871568905 scopus 로고    scopus 로고
    • Trans-Tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4
    • Dhar, S.S., Lee, S.H., Kan, P.Y., Voigt, P., Ma, L., Shi, X., Reinberg, D. and Lee, M.G. (2012) Trans-Tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4. Genes Dev., 26, 2749-2762.
    • (2012) Genes Dev , vol.26 , pp. 2749-2762
    • Dhar, S.S.1    Lee, S.H.2    Kan, P.Y.3    Voigt, P.4    Ma, L.5    Shi, X.6    Reinberg, D.7    Lee, M.G.8
  • 18
    • 84900408448 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats
    • Hasegawa, M., Toma-Fukai, S., Kim, J.D., Fukamizu, A. and Shimizu, T. (2014) Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats. FEBS Lett., 588, 1942-1948.
    • (2014) FEBS Lett , vol.588 , pp. 1942-1948
    • Hasegawa, M.1    Toma-Fukai, S.2    Kim, J.D.3    Fukamizu, A.4    Shimizu, T.5
  • 19
    • 79955079071 scopus 로고    scopus 로고
    • Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1
    • Rust, H.L., Zurita-Lopez, C.I., Clarke, S. and Thompson, P.R. (2011) Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1. Biochemistry, 50, 3332-3345.
    • (2011) Biochemistry , vol.50 , pp. 3332-3345
    • Rust, H.L.1    Zurita-Lopez, C.I.2    Clarke, S.3    Thompson, P.R.4
  • 20
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • Bolstad, B.M., Irizarry, R.A., Astrand, M. and Speed, T.P. (2003) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics, 19, 185-193.
    • (2003) Bioinformatics , vol.19 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 21
    • 51649095946 scopus 로고    scopus 로고
    • Cardiac commitment of primate embryonic stem cells
    • Leschik, J., Stefanovic, S., Brinon, B. and Puceat, M. (2008) Cardiac commitment of primate embryonic stem cells. Nat. Protoc., 3, 1381-1387.
    • (2008) Nat. Protoc , vol.3 , pp. 1381-1387
    • Leschik, J.1    Stefanovic, S.2    Brinon, B.3    Puceat, M.4
  • 22
    • 70450224857 scopus 로고    scopus 로고
    • Gata4 directs development of cardiac-inducing endoderm from ES cells
    • Holtzinger, A., Rosenfeld, G.E. and Evans, T. (2010) Gata4 directs development of cardiac-inducing endoderm from ES cells. Dev. Biol., 337, 63-73.
    • (2010) Dev. Biol , vol.337 , pp. 63-73
    • Holtzinger, A.1    Rosenfeld, G.E.2    Evans, T.3
  • 25
    • 76149087152 scopus 로고    scopus 로고
    • Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
    • Niakan, K.K., Ji, H., Maehr, R., Vokes, S.A., Rodolfa, K.T., Sherwood, R.I., Yamaki, M., Dimos, J.T., Chen, A.E., Melton, D.A. et al. (2010) Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes Dev., 24, 312-326.
    • (2010) Genes Dev , vol.24 , pp. 312-326
    • Niakan, K.K.1    Ji, H.2    Maehr, R.3    Vokes, S.A.4    Rodolfa, K.T.5    Sherwood, R.I.6    Yamaki, M.7    Dimos, J.T.8    Chen, A.E.9    Melton, D.A.10
  • 26
    • 48149098737 scopus 로고    scopus 로고
    • Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells
    • Seguin, C.A., Draper, J.S., Nagy, A. and Rossant, J. (2008) Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells. Cell Stem Cell, 3, 182-195.
    • (2008) Cell Stem Cell , vol.3 , pp. 182-195
    • Seguin, C.A.1    Draper, J.S.2    Nagy, A.3    Rossant, J.4
  • 28
    • 40749104852 scopus 로고    scopus 로고
    • An extended transcriptional network for pluripotency of embryonic stem cells
    • Kim, J., Chu, J., Shen, X., Wang, J. and Orkin, S.H. (2008) An extended transcriptional network for pluripotency of embryonic stem cells. Cell, 132, 1049-1061.
    • (2008) Cell , vol.132 , pp. 1049-1061
    • Kim, J.1    Chu, J.2    Shen, X.3    Wang, J.4    Orkin, S.H.5
  • 29
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K. and Yamanaka, S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126, 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 30
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 31
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel, D.P. (2009) MicroRNAs: Target recognition and regulatory functions. Cell, 136, 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 32
    • 34447639973 scopus 로고    scopus 로고
    • Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression
    • Otsuka, M., Jing, Q., Georgel, P., New, L., Chen, J., Mols, J., Kang, Y.J., Jiang, Z., Du, X., Cook, R. et al. (2007) Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity, 27, 123-134.
    • (2007) Immunity , vol.27 , pp. 123-134
    • Otsuka, M.1    Jing, Q.2    Georgel, P.3    New, L.4    Chen, J.5    Mols, J.6    Kang, Y.J.7    Jiang, Z.8    Du, X.9    Cook, R.10
  • 33
    • 69949098536 scopus 로고    scopus 로고
    • MiR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to 'seedless' 3'UTR microRNA recognition elements
    • Lal, A., Navarro, F., Maher, C.A., Maliszewski, L.E., Yan, N., O'Day, E., Chowdhury, D., Dykxhoorn, D.M., Tsai, P., Hofmann, O. et al. (2009) miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to 'seedless' 3'UTR microRNA recognition elements. Mol. Cell, 35, 610-625.
    • (2009) Mol. Cell , vol.35 , pp. 610-625
    • Lal, A.1    Navarro, F.2    Maher, C.A.3    Maliszewski, L.E.4    Yan, N.5    O'Day, E.6    Chowdhury, D.7    Dykxhoorn, D.M.8    Tsai, P.9    Hofmann, O.10
  • 34
    • 84860389231 scopus 로고    scopus 로고
    • MiR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: A potential for therapeutic intervention
    • Srivastava, N., Manvati, S., Srivastava, A., Pal, R., Kalaiarasan, P., Chattopadhyay, S., Gochhait, S., Dua, R. and Bamezai, R.N. (2011) miR-24-2 controls H2AFX expression regardless of gene copy number alteration and induces apoptosis by targeting antiapoptotic gene BCL-2: A potential for therapeutic intervention. Breast Cancer Res., 13, R39-R50.
    • (2011) Breast Cancer Res , vol.13 , pp. R39-R50
    • Srivastava, N.1    Manvati, S.2    Srivastava, A.3    Pal, R.4    Kalaiarasan, P.5    Chattopadhyay, S.6    Gochhait, S.7    Dua, R.8    Bamezai, R.N.9
  • 37
    • 84865526587 scopus 로고    scopus 로고
    • Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase delta catalytic subunit gene, POLD1
    • Karkhanis, V., Wang, L., Tae, S., Hu, Y.J., Imbalzano, A.N. and Sif, S. (2012) Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase delta catalytic subunit gene, POLD1. J. Biol. Chem., 287, 29801-29814.
    • (2012) J. Biol. Chem , vol.287 , pp. 29801-29814
    • Karkhanis, V.1    Wang, L.2    Tae, S.3    Hu, Y.J.4    Imbalzano, A.N.5    Sif, S.6
  • 38
    • 42049099046 scopus 로고    scopus 로고
    • Protein arginine (N)-methyl transferase 7 (PRMT7) as a potential target for the sensitization of tumor cells to camptothecins
    • Verbiest, V., Montaudon, D., Tautu, M.T., Moukarzel, J., Portail, J.P., Markovits, J., Robert, J., Ichas, F. and Pourquier, P. (2008) Protein arginine (N)-methyl transferase 7 (PRMT7) as a potential target for the sensitization of tumor cells to camptothecins. FEBS Lett., 582, 1483-1489.
    • (2008) FEBS Lett , vol.582 , pp. 1483-1489
    • Verbiest, V.1    Montaudon, D.2    Tautu, M.T.3    Moukarzel, J.4    Portail, J.P.5    Markovits, J.6    Robert, J.7    Ichas, F.8    Pourquier, P.9
  • 39
    • 33751029979 scopus 로고    scopus 로고
    • The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation
    • Jelinic, P., Stehle, J.C. and Shaw, P. (2006) The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation. PLoS Biol., 4, e355.
    • (2006) PLoS Biol , vol.4 , pp. e355
    • Jelinic, P.1    Stehle, J.C.2    Shaw, P.3
  • 40
    • 84866530722 scopus 로고    scopus 로고
    • UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity
    • Wang, C., Lee, J.E., Cho, Y.W., Xiao, Y., Jin, Q., Liu, C. and Ge, K. (2012) UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity. Proc. Natl. Acad. Sci. U.S.A., 109, 15324-15329.
    • (2012) Proc. Natl. Acad. Sci. U.S.A , vol.109 , pp. 15324-15329
    • Wang, C.1    Lee, J.E.2    Cho, Y.W.3    Xiao, Y.4    Jin, Q.5    Liu, C.6    Ge, K.7
  • 41
    • 84875537133 scopus 로고    scopus 로고
    • Epigenetic reprogramming in cancer
    • Suva, M.L., Riggi, N. and Bernstein, B.E. (2013) Epigenetic reprogramming in cancer. Science, 339, 1567-1570.
    • (2013) Science , vol.339 , pp. 1567-1570
    • Suva, M.L.1    Riggi, N.2    Bernstein, B.E.3
  • 42
    • 0344063368 scopus 로고    scopus 로고
    • Oct-3/4 is a dose-dependent oncogenic fate determinant
    • Gidekel, S., Pizov, G., Bergman, Y. and Pikarsky, E. (2003) Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell, 4, 361-370.
    • (2003) Cancer Cell , vol.4 , pp. 361-370
    • Gidekel, S.1    Pizov, G.2    Bergman, Y.3    Pikarsky, E.4
  • 43
    • 77957757417 scopus 로고    scopus 로고
    • A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs
    • Kim, J., Woo, A.J., Chu, J., Snow, J.W., Fujiwara, Y., Kim, C.G., Cantor, A.B. and Orkin, S.H. (2010) A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs. Cell, 143, 313-324.
    • (2010) Cell , vol.143 , pp. 313-324
    • Kim, J.1    Woo, A.J.2    Chu, J.3    Snow, J.W.4    Fujiwara, Y.5    Kim, C.G.6    Cantor, A.B.7    Orkin, S.H.8
  • 44
    • 84907516355 scopus 로고    scopus 로고
    • PRMT7 induces epithelial-To-mesenchymal transition and promotes metastasis in breast cancer
    • Yao, R., Jiang, H., Ma, Y., Wang, L., Wang, L., Du, J., Hou, P., Gao, Y., Zhao, L., Wang, G. et al. (2014) PRMT7 induces epithelial-To-mesenchymal transition and promotes metastasis in breast cancer. Cancer Res., 74, 5656-5667.
    • (2014) Cancer Res , vol.74 , pp. 5656-5667
    • Yao, R.1    Jiang, H.2    Ma, Y.3    Wang, L.4    Wang, L.5    Du, J.6    Hou, P.7    Gao, Y.8    Zhao, L.9    Wang, G.10
  • 45
    • 66149160608 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs promote induced pluripotency
    • Judson, R.L., Babiarz, J.E., Venere, M. and Blelloch, R. (2009) Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat. Biotechnol., 27, 459-461.
    • (2009) Nat. Biotechnol , vol.27 , pp. 459-461
    • Judson, R.L.1    Babiarz, J.E.2    Venere, M.3    Blelloch, R.4
  • 46
    • 56749091922 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation
    • Wang, Y., Baskerville, S., Shenoy, A., Babiarz, J.E., Baehner, L. and Blelloch, R. (2008) Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat. Genet., 40, 1478-1483.
    • (2008) Nat. Genet , vol.40 , pp. 1478-1483
    • Wang, Y.1    Baskerville, S.2    Shenoy, A.3    Babiarz, J.E.4    Baehner, L.5    Blelloch, R.6
  • 47
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
    • Xu, N., Papagiannakopoulos, T., Pan, G., Thomson, J.A. and Kosik, K.S. (2009) MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell, 137, 647-658.
    • (2009) Cell , vol.137 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 49
    • 48649103982 scopus 로고    scopus 로고
    • A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
    • Rybak, A., Fuchs, H., Smirnova, L., Brandt, C., Pohl, E.E., Nitsch, R. andWulczyn, F.G. (2008) A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat. Cell Biol., 10, 987-993.
    • (2008) Nat. Cell Biol , vol.10 , pp. 987-993
    • Rybak, A.1    Fuchs, H.2    Smirnova, L.3    Brandt, C.4    Pohl, E.E.5    Nitsch, R.6    Wulczyn, F.G.7
  • 50
    • 43449100341 scopus 로고    scopus 로고
    • REST maintains self-renewal and pluripotency of embryonic stem cells
    • Singh, S.K., Kagalwala, M.N., Parker-Thornburg, J., Adams, H. and Majumder, S. (2008) REST maintains self-renewal and pluripotency of embryonic stem cells. Nature, 453, 223-227.
    • (2008) Nature , vol.453 , pp. 223-227
    • Singh, S.K.1    Kagalwala, M.N.2    Parker-Thornburg, J.3    Adams, H.4    Majumder, S.5
  • 51
    • 84858446579 scopus 로고    scopus 로고
    • MicroRNAs and their targets: Recognition, regulation and an emerging reciprocal relationship
    • Pasquinelli, A.E. (2012) MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet., 13, 271-282.
    • (2012) Nat. Rev. Genet , vol.13 , pp. 271-282
    • Pasquinelli, A.E.1
  • 53
    • 36849048778 scopus 로고    scopus 로고
    • Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
    • Diederichs, S. and Haber, D.A. (2007) Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell, 131, 1097-1108.
    • (2007) Cell , vol.131 , pp. 1097-1108
    • Diederichs, S.1    Haber, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.