Genetic defects in β-spectrin and tau sensitize C. Elegans axons to movement-induced damage via torque-tension coupling

eLife

Volumn 6, Issue , 2017, Pages

  Krieg, Michael ^a,c   Stühmer, Jan ^b   Cueva, Juan G ^a   Fetter, Richard ^a   Spilker, Kerri ^a,d   Cremers, Daniel ^b   Shen, Kang ^a   Dunn, Alexander R ^a   Goodman, Miriam B ^a  

^a STANFORD UNIVERSITY   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c ICFO INSTITUT DE CIENCIES FOTONIQUES   (Spain)

^d BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACYLTRANSFERASE; BETA TUBULIN; GREEN FLUORESCENT PROTEIN; SPECTRIN; TAU PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; MEC-7 PROTEIN, C ELEGANS; MICROTUBULE ASSOCIATED PROTEIN; PTL-1 PROTEIN, C ELEGANS; TUBULIN; UNC-70 PROTEIN, C ELEGANS;

ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AXON; BIOPHYSICS; BLEACHING; CAENORHABDITIS ELEGANS; CELL CULTURE; CONFOCAL MICROSCOPY; DENDRITE; ELASTICITY; EMBRYO; FLUORESCENCE MICROSCOPY; GENETIC DISORDER; LOSS OF FUNCTION MUTATION; MECHANICAL STRESS; MICROTUBULE; MISSENSE MUTATION; NEUROPROTECTION; NONHUMAN; PARTICLE IMAGE VELOCIMETRY; PHENOTYPE; POLYMERASE CHAIN REACTION; RIGIDITY; RNA SEQUENCE; SHEAR STRESS; SIMULATION; TENSION; TORQUE; TRANSGENIC ANIMAL; TRANSGENICS; TRANSMISSION ELECTRON MICROSCOPY; YOUNG ADULT; ANIMAL; DEFICIENCY; GENETICS; MOVEMENT (PHYSIOLOGY); PHYSIOLOGY;

ANIMALS; AXONS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MOVEMENT; SPECTRIN; STRESS, MECHANICAL; TORQUE; TUBULIN;

EID: 85012170365     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.20172     Document Type: Article

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