Direct force measurements reveal that protein Tau confers short-range attractions and isoform-dependent steric stabilization to microtubules

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 47, 2015, Pages E6416-E6425

  Chung, Peter J ^a,b   Choi, Myung Chul ^c   Miller, Herbert P ^b   Feinstein, H Eric ^b,e   Raviv, Uri ^d   Li, Youli ^b   Wilson, Leslie ^b   Feinstein, Stuart C ^b   Safinya, Cyrus R ^a,b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^e Quality and Compliance Department   (United States)

Author keywords

Force measurement; Intrinsically disordered proteins; Microtubule; SAXS; Tau

Indexed keywords

ISOPROTEIN; PACLITAXEL; POLYELECTROLYTE; TAU PROTEIN; PROTEIN BINDING;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; FLUORESCENCE MICROSCOPY; LIGHT SCATTERING; MICROTUBULE; MONTE CARLO METHOD; MUSHROOM; NERVE FIBER; NERVE FIBER DEGENERATION; NONHUMAN; OSMOTIC PRESSURE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN INTERACTION; X RAY CRYSTALLOGRAPHY; ANIMAL; BIOPHYSICS; BOVINE; HUMAN; METABOLISM; MOLECULAR MODEL;

ANIMALS; BIOPHYSICAL PHENOMENA; CATTLE; HUMANS; MICROTUBULES; MODELS, MOLECULAR; OSMOTIC PRESSURE; PROTEIN BINDING; PROTEIN ISOFORMS; TAU PROTEINS;

EID: 84948128616     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1513172112     Document Type: Article

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