-
1
-
-
0032578911
-
Specific interference by ingested dsRNA
-
L. Timmons and A. Fire, "Specific interference by ingested dsRNA," Nature, vol. 395, no. 6705, p. 854, 1998.
-
(1998)
Nature
, vol.395
, Issue.6705
, pp. 854
-
-
Timmons, L.1
Fire, A.2
-
2
-
-
0032417618
-
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
-
M. K. Montgomery, S. Xu, and A. Fire, "RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans," Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 26, pp. 15502-15507, 1998.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.26
, pp. 15502-15507
-
-
Montgomery, M.K.1
Xu, S.2
Fire, A.3
-
3
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
S. M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl, "Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells," Nature, vol. 411, no. 6836, pp. 494-498, 2001.
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
4
-
-
3142615372
-
The RNAi revolution
-
C. D. Novina and P. A. Sharp, "The RNAi revolution," Nature, vol. 430, no. 6996, pp. 161-164, 2004.
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 161-164
-
-
Novina, C.D.1
Sharp, P.A.2
-
5
-
-
34248682403
-
RNAi therapeutics: Principles, prospects and challenges
-
L. Aagaard and J. J. Rossi, "RNAi therapeutics: principles, prospects and challenges,"AdvancedDrugDelivery Reviews, vol. 59, no. 2-3, pp. 75-86, 2007.
-
(2007)
AdvancedDrugDelivery Reviews
, vol.59
, Issue.23
, pp. 75-86
-
-
Aagaard, L.1
Rossi, J.J.2
-
6
-
-
84979640338
-
Inhibition of influenza A virus matrix and nonstructural gene expression using RNA interference
-
C. M. McMillen, D. H. Beezhold, F. M. Blachere, S. Othumpangat, M. L. Kashon, and J. D. Noti, "Inhibition of influenza A virus matrix and nonstructural gene expression using RNA interference," Virology, vol. 497, pp. 171-184, 2016.
-
(2016)
Virology
, vol.497
, pp. 171-184
-
-
McMillen, C.M.1
Beezhold, D.H.2
Blachere, F.M.3
Othumpangat, S.4
Kashon, M.L.5
Noti, J.D.6
-
7
-
-
84962787550
-
Using small RNA deep sequencing data to detect human viruses
-
F. Wang, Y. Sun, J. Ruan et al. , "Using small RNA deep sequencing data to detect human viruses," BioMed Research International, vol. 2016, Article ID 2596782, 9 pages, 2016.
-
(2016)
BioMed Research International
, vol.2016
, pp. 9
-
-
Wang, F.1
Sun, Y.2
Ruan, J.3
-
8
-
-
84975502218
-
Challenges and opportunities for siRNA-based cancer treatment
-
T. Wang, S. Shigdar, H. A. Shamaileh et al. , "Challenges and opportunities for siRNA-based cancer treatment," Cancer Letters, vol. 387, no. 28, pp. 77-83, 2017.
-
(2017)
Cancer Letters
, vol.387
, Issue.28
, pp. 77-83
-
-
Wang, T.1
Shigdar, S.2
Shamaileh, H.A.3
-
9
-
-
34047177954
-
Specific residues at every third position of siRNA shape its efficient RNAi activity
-
T. Katoh and T. Suzuki, "Specific residues at every third position of siRNA shape its efficient RNAi activity," Nucleic Acids Research, vol. 35, no. 4, article no. e27, 2007.
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.4
-
-
Katoh, T.1
Suzuki, T.2
-
10
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
S. M. Elbashir, J. Harborth, K. Weber, and T. Tuschl, "Analysis of gene function in somatic mammalian cells using small interfering RNAs," Methods, vol. 26, no. 2, pp. 199-213, 2002.
-
(2002)
Methods
, vol.26
, Issue.2
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
11
-
-
1542336952
-
Rational siRNA design for RNA interference
-
A. Reynolds,D. Leake,Q. Boese, S. Scaringe,W. S. Marshall, and A. Khvorova, "Rational siRNA design for RNA interference," Nature Biotechnology, vol. 22, no. 3, pp. 326-330, 2004.
-
(2004)
Nature Biotechnology
, vol.22
, Issue.3
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
12
-
-
1642273831
-
An algorithm for selection of functional siRNA sequences
-
M. Amarzguioui and H. Prydz, "An algorithm for selection of functional siRNA sequences," Biochemical and Biophysical Research Communications, vol. 316, no. 4, pp. 1050-1058, 2004.
-
(2004)
Biochemical and Biophysical Research Communications
, vol.316
, Issue.4
, pp. 1050-1058
-
-
Amarzguioui, M.1
Prydz, H.2
-
13
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
A. Khvorova, A. Reynolds, and S. D. Jayasena, "Functional siRNAs and miRNAs exhibit strand bias," Cell, vol. 115, no. 2, pp. 209-216, 2003.
-
(2003)
Cell
, vol.115
, Issue.2
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
14
-
-
1642346273
-
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference
-
K. Ui-Tei, Y. Naito, F. Takahashi et al. , "Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference," Nucleic Acids Research, vol. 32,no. 3, pp. 936-948, 2004.
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.3
, pp. 936-948
-
-
Ui-Tei, K.1
Naito, Y.2
Takahashi, F.3
-
15
-
-
17444412299
-
Local RNA target structure influences siRNA efficacy: Systematic analysis of intentionally designed binding regions
-
S. Schubert, A. Grünweller, V. A. Erdmann, and J. Kurreck, "Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions," Journal of Molecular Biology, vol. 348, no. 4, pp. 883-893, 2005.
-
(2005)
Journal of Molecular Biology
, vol.348
, Issue.4
, pp. 883-893
-
-
Schubert, S.1
Grünweller, A.2
Erdmann, V.A.3
Kurreck, J.4
-
16
-
-
1942488998
-
The gene-silencing efficiency of siRNA is strongly dependent on the local structure of mRNA at the targeted region
-
K. Q. Luo and D. C. Chang, "The gene-silencing efficiency of siRNA is strongly dependent on the local structure of mRNA at the targeted region," Biochemical and Biophysical Research Communications, vol. 318, no. 1, pp. 303-310, 2004.
-
(2004)
Biochemical and Biophysical Research Communications
, vol.318
, Issue.1
, pp. 303-310
-
-
Luo, K.Q.1
Chang, D.C.2
-
17
-
-
13444282536
-
Filtering of ineffective siRNAs and improved siRNA design tool
-
S. M. Yiu, P. W. H. Wong, T. W. Lam et al. , "Filtering of ineffective siRNAs and improved siRNA design tool," Bioinformatics, vol. 21, no. 2, pp. 144-151, 2005.
-
(2005)
Bioinformatics
, vol.21
, Issue.2
, pp. 144-151
-
-
Yiu, S.M.1
Wong, P.W.H.2
Lam, T.W.3
-
18
-
-
33645822531
-
SiRecords: An extensive database of mammalian siRNAs with efficacy ratings
-
Y. Ren,W. Gong, Q. Xu et al. , "siRecords: an extensive database of mammalian siRNAs with efficacy ratings," Bioinformatics, vol. 22, no. 8, pp. 1027-1028, 2006.
-
(2006)
Bioinformatics
, vol.22
, Issue.8
, pp. 1027-1028
-
-
Ren, Y.1
Gong, W.2
Xu, Q.3
-
19
-
-
3543019112
-
A comparison of siRNA efficacy predictors
-
P. Sætrom and O. Snøve Jr. , "A comparison of siRNA efficacy predictors," Biochemical and Biophysical Research Communications, vol. 321, no. 1, pp. 247-253, 2004.
-
(2004)
Biochemical and Biophysical Research Communications
, vol.321
, Issue.1
, pp. 247-253
-
-
Sætrom, P.1
Snøve, O.2
-
20
-
-
23444437819
-
Design of a genomewide siRNA library using an artificial neural network
-
D. Huesken, J. Lange, C. Mickanin et al. , "Design of a genomewide siRNA library using an artificial neural network," Nature Biotechnology, vol. 23, no. 8, pp. 995-1001, 2005.
-
(2005)
Nature Biotechnology
, vol.23
, Issue.8
, pp. 995-1001
-
-
Huesken, D.1
Lange, J.2
Mickanin, C.3
-
21
-
-
33748701701
-
Computational models with thermodynamic and composition features improve siRNA design
-
S. A. Shabalina, A. N. Spiridonov, and A. Y. Ogurtsov, "Computational models with thermodynamic and composition features improve siRNA design," BMC Bioinformatics, vol. 7, article no. 65, 2006.
-
(2006)
BMC Bioinformatics
, vol.7
-
-
Shabalina, S.A.1
Spiridonov, A.N.2
Ogurtsov, A.Y.3
-
22
-
-
33845663097
-
An accurate and interpretablemodel for siRNAefficacy prediction
-
J.-P. Vert, N. Foveau, C. Lajaunie, and Y. Vandenbrouck, "An accurate and interpretablemodel for siRNAefficacy prediction," BMC Bioinformatics, vol. 7, article no. 520, 2006.
-
(2006)
BMC Bioinformatics
, vol.7
-
-
Vert, J.-P.1
Foveau, N.2
Lajaunie, C.3
Vandenbrouck, Y.4
-
23
-
-
35548980865
-
Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities
-
M. Ichihara, Y. Murakumo, A. Masuda et al. , "Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities," Nucleic Acids Research, vol. 35, no. 18, article no. e123, 2007.
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.18
-
-
Ichihara, M.1
Murakumo, Y.2
Masuda, A.3
-
24
-
-
34250309149
-
Comparison of approaches for rational siRNA design leading to a new efficient and transparent method
-
O. Matveeva, Y. Nechipurenko, L. Rossi et al. , "Comparison of approaches for rational siRNA design leading to a new efficient and transparent method," Nucleic Acids Research, vol. 35, no. 8, article no. e63, 2007.
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.8
-
-
Matveeva, O.1
Nechipurenko, Y.2
Rossi, L.3
-
25
-
-
84928159849
-
A semi-supervised tensor regression model for siRNA efficacy prediction
-
B. N. Thang, T. B. Ho, and T. Kanda, "A semi-supervised tensor regression model for siRNA efficacy prediction," BMC Bioinformatics, vol. 16, no. 1, article no. 80, 2015.
-
(2015)
BMC Bioinformatics
, vol.16
, Issue.1
-
-
Thang, B.N.1
Ho, T.B.2
Kanda, T.3
-
26
-
-
84899888621
-
Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells
-
T. Takahashi, S. Zenno, O. Ishibashi, T. Takizawa, K. Saigo, and K. Ui-Tei, "Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells," Nucleic Acids Research, vol. 42, no. 8, pp. 5256-5269, 2014.
-
(2014)
Nucleic Acids Research
, vol.42
, Issue.8
, pp. 5256-5269
-
-
Takahashi, T.1
Zenno, S.2
Ishibashi, O.3
Takizawa, T.4
Saigo, K.5
Ui-Tei, K.6
-
27
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
J. Harborth, S. M. Elbashir, K. Vandenburgh et al. , "Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing," Antisense and Nucleic Acid Drug Development, vol. 13, no. 2, pp. 83-105, 2003.
-
(2003)
Antisense and Nucleic Acid Drug Development
, vol.13
, Issue.2
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
-
28
-
-
0037470145
-
Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis
-
T. A. Vickers, S. Koo, C. F. Bennett, S. T. Crooke, N. M. Dean, and B. F. Baker, "Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis," Journal of Biological Chemistry, vol. 278, no. 9, pp. 7108-7118, 2003.
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.9
, pp. 7108-7118
-
-
Vickers, T.A.1
Koo, S.2
Bennett, C.F.3
Crooke, S.T.4
Dean, N.M.5
Baker, B.F.6
-
29
-
-
0032552882
-
Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs
-
T. Xia, J. SantaLucia Jr. , M. E. Burkard et al. , "Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson-Crick base pairs," Biochemistry, vol. 37, no. 42, pp. 14719-14735, 1998.
-
(1998)
Biochemistry
, vol.37
, Issue.42
, pp. 14719-14735
-
-
Xia, T.1
SantaLucia, J.2
Burkard, M.E.3
-
30
-
-
19444386649
-
Prediction of siRNA functionality using generalized string kernel and support vectormachine
-
R. Teramoto, M. Aoki,T. Kimura, and M. Kanaoka, "Prediction of siRNA functionality using generalized string kernel and support vectormachine," FEBS Letters, vol. 579, no. 13, pp. 2878-2882, 2005.
-
(2005)
FEBS Letters
, vol.579
, Issue.13
, pp. 2878-2882
-
-
Teramoto, R.1
Aoki, M.2
Kimura, T.3
Kanaoka, M.4
-
31
-
-
84874364730
-
Influence of mRNA features on siRNA interference efficacy
-
Y. Liu, Y. Chang, C. Zhang et al. , "Influence of mRNA features on siRNA interference efficacy," Journal of Bioinformatics and Computational Biology, vol. 11, no. 3, Article ID 1341004, 2013.
-
(2013)
Journal of Bioinformatics and Computational Biology
, vol.11
, Issue.3
-
-
Liu, Y.1
Chang, Y.2
Zhang, C.3
-
32
-
-
0035478854
-
Random forests
-
L. Breiman, "Random forests," Machine Learning, vol. 45, no. 1, pp. 5-32, 2001.
-
(2001)
Machine Learning
, vol.45
, Issue.1
, pp. 5-32
-
-
Breiman, L.1
-
33
-
-
2342564353
-
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens
-
A. C. Hsieh, R. Bo, J. Manola et al. , "A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens," Nucleic Acids Research, vol. 32, no. 3, pp. 893-901, 2004.
-
(2004)
Nucleic Acids Research
, vol.32
, Issue.3
, pp. 893-901
-
-
Hsieh, A.C.1
Bo, R.2
Manola, J.3
-
34
-
-
3542992506
-
An effective method for selecting siRNA target sequences in mammalian cells
-
S. Takasaki, S. Kotani, and A. Konagaya, "An effective method for selecting siRNA target sequences in mammalian cells," Cell Cycle, vol. 3, no. 6, pp. 790-795, 2004.
-
(2004)
Cell Cycle
, vol.3
, Issue.6
, pp. 790-795
-
-
Takasaki, S.1
Kotani, S.2
Konagaya, A.3
|