Reconciled rat and human metabolic networks for comparative toxicogenomics and biomarker predictions

Nature Communications

Volumn 8, Issue , 2017, Pages

  Blais, Edik M ^a   Rawls, Kristopher D ^a   Dougherty, Bonnie V ^a   Li, Zhuo I ^a   Kolling, Glynis L ^b   Ye, Ping ^c,d   Wallqvist, Anders ^c   Papin, Jason A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

^d Avera Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; BIOLOGICAL MARKER; CA 19-9 ANTIGEN; CAFFEINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE 3; PROSTAGLANDIN E2; THEOPHYLLINE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

BIOMARKER; GENE EXPRESSION; GENOTOXICITY; METABOLISM; METABOLITE; RECONSTRUCTION; RODENT;

ANIMAL CELL; ARTICLE; BILE ACID SYNTHESIS; CELL GROWTH; CONTROLLED STUDY; ENZYME REGULATION; GENE EXPRESSION; GENOMICS; GLYCOSYLATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; LIVER CELL; METABOLISM; NONHUMAN; RAT; SPECIES DIFFERENCE; TOXICOGENETICS; TRANSCRIPTOMICS; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; GENE EXPRESSION PROFILING; GENETICS; INFORMATION PROCESSING; METABOLOMICS; PROCEDURES; VALIDATION STUDY;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; BIOMARKERS; COMPUTATIONAL BIOLOGY; DATASETS AS TOPIC; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; METABOLIC NETWORKS AND PATHWAYS; METABOLOMICS; MODELS, BIOLOGICAL; RATS; SPECIES SPECIFICITY; TOXICOGENETICS;

EID: 85012009478     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14250     Document Type: Article

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