-
1
-
-
0033580813
-
Systems properties of the Haemophilus influenzae Rd metabolic genotype
-
10.1074/jbc.274.25.17410, 10364169
-
Edwards JS, Palsson BO. Systems properties of the Haemophilus influenzae Rd metabolic genotype. J Biol Chem 1999, 274:17410-17416. 10.1074/jbc.274.25.17410, 10364169.
-
(1999)
J Biol Chem
, vol.274
, pp. 17410-17416
-
-
Edwards, J.S.1
Palsson, B.O.2
-
2
-
-
71149117622
-
Metabolic systems biology
-
10.1016/j.febslet.2009.09.031, 19769971
-
Palsson B. Metabolic systems biology. FEBS Lett 2009, 583:3900-3904. 10.1016/j.febslet.2009.09.031, 19769971.
-
(2009)
FEBS Lett
, vol.583
, pp. 3900-3904
-
-
Palsson, B.1
-
3
-
-
45149111660
-
The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli
-
10.1038/nbt1401, 18536691
-
Feist AM, Palsson B. The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli. Nat Biotechnol 2008, 26:659-667. 10.1038/nbt1401, 18536691.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 659-667
-
-
Feist, A.M.1
Palsson, B.2
-
4
-
-
75149129569
-
A protocol for generating a high-quality genome-scale metabolic reconstruction
-
10.1038/nprot.2009.203, 20057383
-
Thiele I, Palsson B. A protocol for generating a high-quality genome-scale metabolic reconstruction. Nat Protoc 2010, 5:93-121. 10.1038/nprot.2009.203, 20057383.
-
(2010)
Nat Protoc
, vol.5
, pp. 93-121
-
-
Thiele, I.1
Palsson, B.2
-
5
-
-
9544253891
-
Genome-scale models of microbial cells: evaluating the consequences of constraints
-
10.1038/nrmicro1023, 15494745
-
Price ND, Reed JL, Palsson B. Genome-scale models of microbial cells: evaluating the consequences of constraints. Nat Rev Microbiol 2004, 2:886-897. 10.1038/nrmicro1023, 15494745.
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 886-897
-
-
Price, N.D.1
Reed, J.L.2
Palsson, B.3
-
6
-
-
34347258175
-
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox
-
10.1038/nprot.2007.99, 17406635
-
Becker SA, Feist AM, Mo ML, Hannum G, Palsson B, Herrgard MJ. Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox. Nat Protoc 2007, 2:727-738. 10.1038/nprot.2007.99, 17406635.
-
(2007)
Nat Protoc
, vol.2
, pp. 727-738
-
-
Becker, S.A.1
Feist, A.M.2
Mo, M.L.3
Hannum, G.4
Palsson, B.5
Herrgard, M.J.6
-
7
-
-
33751226921
-
Systems approach to refining genome annotation
-
10.1073/pnas.0603364103, 1859954, 17088549
-
Reed JL, Patel TR, Chen KH, Joyce AR, Applebee MK, Herring CD, Bui OT, Knight EM, Fong SS, Palsson BO. Systems approach to refining genome annotation. Proc Natl Acad Sci USA 2006, 103:17480-17484. 10.1073/pnas.0603364103, 1859954, 17088549.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17480-17484
-
-
Reed, J.L.1
Patel, T.R.2
Chen, K.H.3
Joyce, A.R.4
Applebee, M.K.5
Herring, C.D.6
Bui, O.T.7
Knight, E.M.8
Fong, S.S.9
Palsson, B.O.10
-
8
-
-
54449092307
-
A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: iJN746 as a cell factory
-
10.1186/1752-0509-2-79, 2569920, 18793442
-
Nogales J, Palsson B, Thiele I. A genome-scale metabolic reconstruction of Pseudomonas putida KT2440: iJN746 as a cell factory. BMC Syst Biol 2008, 2:79. 10.1186/1752-0509-2-79, 2569920, 18793442.
-
(2008)
BMC Syst Biol
, vol.2
, pp. 79
-
-
Nogales, J.1
Palsson, B.2
Thiele, I.3
-
9
-
-
33645460106
-
Chance and necessity in the evolution of minimal metabolic networks
-
10.1038/nature04568, 16572170
-
Pál C, Papp B, Lercher MJ, Csermely P, Oliver SG, Hurst LD. Chance and necessity in the evolution of minimal metabolic networks. Nature 2006, 440:667-670. 10.1038/nature04568, 16572170.
-
(2006)
Nature
, vol.440
, pp. 667-670
-
-
Pál, C.1
Papp, B.2
Lercher, M.J.3
Csermely, P.4
Oliver, S.G.5
Hurst, L.D.6
-
10
-
-
70349345898
-
Three-dimensional structural view of the central metabolic network of Thermotoga maritima
-
Zhang Y, Thiele I, Weekes D, Li Z, Jaroszewski L, Ginalski K, Deacon AM, Wooley J, Lesley SA, Wilson IA, Palsson B, Osterman A, Godzik A. Three-dimensional structural view of the central metabolic network of Thermotoga maritima. Science (80-) 2009, 325:1544-1549.
-
(2009)
Science (80-)
, vol.325
, pp. 1544-1549
-
-
Zhang, Y.1
Thiele, I.2
Weekes, D.3
Li, Z.4
Jaroszewski, L.5
Ginalski, K.6
Deacon, A.M.7
Wooley, J.8
Lesley, S.A.9
Wilson, I.A.10
Palsson, B.11
Osterman, A.12
Godzik, A.13
-
11
-
-
34249934691
-
Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation
-
10.1073/pnas.0702609104, 1857225, 17463081
-
Park JH, Lee KH, Kim TY, Lee SY. Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation. Proc Natl Acad Sci USA 2007, 104:7797-7802. 10.1073/pnas.0702609104, 1857225, 17463081.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7797-7802
-
-
Park, J.H.1
Lee, K.H.2
Kim, T.Y.3
Lee, S.Y.4
-
12
-
-
73149122136
-
Applications of genome-scale metabolic reconstructions
-
10.1038/msb.2009.77, 2795471, 19888215
-
Oberhardt MA, Palsson B, Papin JA. Applications of genome-scale metabolic reconstructions. Mol Syst Biol 2009, 5:320. 10.1038/msb.2009.77, 2795471, 19888215.
-
(2009)
Mol Syst Biol
, vol.5
, pp. 320
-
-
Oberhardt, M.A.1
Palsson, B.2
Papin, J.A.3
-
13
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
10.1038/35057062, 11237011
-
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, Kann L, Lehoczky J, LeVine R, McEwan P, McKernan K, Meldrim J, Mesirov JP, Miranda C, Morris W, Naylor J, Raymond C, Rosetti M, Santos R, Sheridan A, Sougnez C. Initial sequencing and analysis of the human genome. Nature 2001, 409:860-921. 10.1038/35057062, 11237011.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
FitzHugh, W.10
Funke, R.11
Gage, D.12
Harris, K.13
Heaford, A.14
Howland, J.15
Kann, L.16
Lehoczky, J.17
LeVine, R.18
McEwan, P.19
McKernan, K.20
Meldrim, J.21
Mesirov, J.P.22
Miranda, C.23
Morris, W.24
Naylor, J.25
Raymond, C.26
Rosetti, M.27
Santos, R.28
Sheridan, A.29
Sougnez, C.30
more..
-
14
-
-
14844326483
-
Computational prediction of human metabolic pathways from the complete human genome
-
10.1186/gb-2004-6-1-r2, 549063, 15642094
-
Romero P, Wagg J, Green ML, Kaiser D, Krummenacker M, Karp PD. Computational prediction of human metabolic pathways from the complete human genome. Genome Biol 2005, 6:R2. 10.1186/gb-2004-6-1-r2, 549063, 15642094.
-
(2005)
Genome Biol
, vol.6
-
-
Romero, P.1
Wagg, J.2
Green, M.L.3
Kaiser, D.4
Krummenacker, M.5
Karp, P.D.6
-
15
-
-
77954791900
-
Compartmentalization of the Edinburgh Human Metabolic Network
-
10.1186/1471-2105-11-393, 2918583, 20649990
-
Hao T, Ma H, Zhao X, Goryanin I. Compartmentalization of the Edinburgh Human Metabolic Network. BMC Bioinformatics 2010, 11:393. 10.1186/1471-2105-11-393, 2918583, 20649990.
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 393
-
-
Hao, T.1
Ma, H.2
Zhao, X.3
Goryanin, I.4
-
16
-
-
34548860112
-
The Edinburgh human metabolic network reconstruction and its functional analysis
-
10.1038/msb4100177, 2013923, 17882155
-
Ma H, Sorokin A, Mazein A, Selkov A, Selkov E, Demin O, Goryanin I. The Edinburgh human metabolic network reconstruction and its functional analysis. Mol Syst Biol 2007, 3:135. 10.1038/msb4100177, 2013923, 17882155.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 135
-
-
Ma, H.1
Sorokin, A.2
Mazein, A.3
Selkov, A.4
Selkov, E.5
Demin, O.6
Goryanin, I.7
-
17
-
-
33846910173
-
Global reconstruction of the human metabolic network based on genomic and bibliomic data
-
10.1073/pnas.0610772104, 1794290, 17267599
-
Duarte NC, Becker SA, Jamshidi N, Thiele I, Mo ML, Vo TD, Srivas R, Palsson B. Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc Natl Acad Sci USA 2007, 104:1777-1782. 10.1073/pnas.0610772104, 1794290, 17267599.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1777-1782
-
-
Duarte, N.C.1
Becker, S.A.2
Jamshidi, N.3
Thiele, I.4
Mo, M.L.5
Vo, T.D.6
Srivas, R.7
Palsson, B.8
-
18
-
-
48249158278
-
The implications of human metabolic network topology for disease comorbidity
-
10.1073/pnas.0802208105, 2481357, 18599447
-
Lee D, Park J, Kay KA, Christakis NA, Oltvai ZN, Barabási A. The implications of human metabolic network topology for disease comorbidity. Proc Natl Acad Sci USA 2008, 105:9880-9885. 10.1073/pnas.0802208105, 2481357, 18599447.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9880-9885
-
-
Lee, D.1
Park, J.2
Kay, K.A.3
Christakis, N.A.4
Oltvai, Z.N.5
Barabási, A.6
-
19
-
-
51349092391
-
Network-based prediction of human tissue-specific metabolism
-
10.1038/nbt.1487, 18711341
-
Shlomi T, Cabili MN, Herrgård MJ, Palsson B, Ruppin E. Network-based prediction of human tissue-specific metabolism. Nat Biotechnol 2008, 26:1003-1010. 10.1038/nbt.1487, 18711341.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1003-1010
-
-
Shlomi, T.1
Cabili, M.N.2
Herrgård, M.J.3
Palsson, B.4
Ruppin, E.5
-
20
-
-
66349089524
-
Genome-scale network analysis of imprinted human metabolic genes
-
10.4161/epi.4.1.7603, 19218833
-
Sigurdsson MI, Jamshidi N, Jonsson JJ, Palsson BO. Genome-scale network analysis of imprinted human metabolic genes. Epigenetics 2009, 4:43-46. 10.4161/epi.4.1.7603, 19218833.
-
(2009)
Epigenetics
, vol.4
, pp. 43-46
-
-
Sigurdsson, M.I.1
Jamshidi, N.2
Jonsson, J.J.3
Palsson, B.O.4
-
21
-
-
65349131424
-
Reconstruction of metabolic pathways for the cattle genome
-
10.1186/1752-0509-3-33, 2669051, 19284618
-
Seo S, Lewin HA. Reconstruction of metabolic pathways for the cattle genome. BMC Syst Biol 2009, 3:33. 10.1186/1752-0509-3-33, 2669051, 19284618.
-
(2009)
BMC Syst Biol
, vol.3
, pp. 33
-
-
Seo, S.1
Lewin, H.A.2
-
22
-
-
70049109588
-
MouseCyc: a curated biochemical pathways database for the laboratory mouse
-
10.1186/gb-2009-10-8-r84, 2745765, 19682380
-
Evsikov AV, Dolan ME, Genrich MP, Patek E, Bult CJ. MouseCyc: a curated biochemical pathways database for the laboratory mouse. Genome Biol 2009, 10:R84. 10.1186/gb-2009-10-8-r84, 2745765, 19682380.
-
(2009)
Genome Biol
, vol.10
-
-
Evsikov, A.V.1
Dolan, M.E.2
Genrich, M.P.3
Patek, E.4
Bult, C.J.5
-
23
-
-
67651209209
-
On the reconstruction of the Mus musculus genome-scale metabolic network model
-
full_text, 19425150
-
Quek L, Nielsen LK. On the reconstruction of the Mus musculus genome-scale metabolic network model. Genome Inform 2008, 21:89-100. full_text, 19425150.
-
(2008)
Genome Inform
, vol.21
, pp. 89-100
-
-
Quek, L.1
Nielsen, L.K.2
-
24
-
-
72949118860
-
Genome-scale modeling and in silico analysis of mouse cell metabolic network
-
10.1039/b912865d, 20024077
-
Selvarasu S, Karimi IA, Ghim G, Lee D. Genome-scale modeling and in silico analysis of mouse cell metabolic network. Mol Biosyst 2010, 6:152-161. 10.1039/b912865d, 20024077.
-
(2010)
Mol Biosyst
, vol.6
, pp. 152-161
-
-
Selvarasu, S.1
Karimi, I.A.2
Ghim, G.3
Lee, D.4
-
25
-
-
13544265458
-
Modeling hybridoma cell metabolism using a generic genome-scale metabolic model of Mus musculus
-
10.1021/bp0498138, 15903248
-
Sheikh K, Förster J, Nielsen LK. Modeling hybridoma cell metabolism using a generic genome-scale metabolic model of Mus musculus. Biotechnol Prog 2005, 21:112-121. 10.1021/bp0498138, 15903248.
-
(2005)
Biotechnol Prog
, vol.21
, pp. 112-121
-
-
Sheikh, K.1
Förster, J.2
Nielsen, L.K.3
-
26
-
-
0026603416
-
Network analysis of intermediary metabolism using linear optimization. II. Interpretation of hybridoma cell metabolism
-
10.1016/S0022-5193(05)80162-6, 1593897
-
Savinell JM, Palsson BO. Network analysis of intermediary metabolism using linear optimization. II. Interpretation of hybridoma cell metabolism. J Theor Biol 1992, 154:455-473. 10.1016/S0022-5193(05)80162-6, 1593897.
-
(1992)
J Theor Biol
, vol.154
, pp. 455-473
-
-
Savinell, J.M.1
Palsson, B.O.2
-
27
-
-
58149197592
-
The Mouse Genome Database genotypes::phenotypes
-
10.1093/nar/gkn886, 2686566, 18981050
-
Blake JA, Bult CJ, Eppig JT, Kadin JA, Richardson JE. The Mouse Genome Database genotypes::phenotypes. Nucleic Acids Res 2009, 37:D712-9. 10.1093/nar/gkn886, 2686566, 18981050.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Blake, J.A.1
Bult, C.J.2
Eppig, J.T.3
Kadin, J.A.4
Richardson, J.E.5
-
28
-
-
58149200954
-
Database resources of the National Center for Biotechnology Information
-
10.1093/nar/gkn741, 2686545, 18940862
-
Sayers EW, Barrett T, Benson DA, Bryant SH, Canese K, Chetvernin V, Church DM, DiCuccio M, Edgar R, Federhen S, Feolo M, Geer LY, Helmberg W, Kapustin Y, Landsman D, Lipman DJ, Madden TL, Maglott DR, Miller V, Mizrachi I, Ostell J, Pruitt KD, Schuler GD, Sequeira E, Sherry ST, Shumway M, Sirotkin K, Souvorov A, Starchenko G, Tatusova TA. Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 2009, 37:D5-15. 10.1093/nar/gkn741, 2686545, 18940862.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Sayers, E.W.1
Barrett, T.2
Benson, D.A.3
Bryant, S.H.4
Canese, K.5
Chetvernin, V.6
Church, D.M.7
DiCuccio, M.8
Edgar, R.9
Federhen, S.10
Feolo, M.11
Geer, L.Y.12
Helmberg, W.13
Kapustin, Y.14
Landsman, D.15
Lipman, D.J.16
Madden, T.L.17
Maglott, D.R.18
Miller, V.19
Mizrachi, I.20
Ostell, J.21
Pruitt, K.D.22
Schuler, G.D.23
Sequeira, E.24
Sherry, S.T.25
Shumway, M.26
Sirotkin, K.27
Souvorov, A.28
Starchenko, G.29
Tatusova, T.A.30
more..
-
29
-
-
20144387806
-
Comparison of fine-scale recombination rates in humans and chimpanzees
-
Winckler W, Myers SR, Richter DJ, Onofrio RC, McDonald GJ, Bontrop RE, McVean GAT, Gabriel SB, Reich D, Donnelly P, Altshuler D. Comparison of fine-scale recombination rates in humans and chimpanzees. Science (80-) 2005, 308:107-111.
-
(2005)
Science (80-)
, vol.308
, pp. 107-111
-
-
Winckler, W.1
Myers, S.R.2
Richter, D.J.3
Onofrio, R.C.4
McDonald, G.J.5
Bontrop, R.E.6
McVean, G.A.T.7
Gabriel, S.B.8
Reich, D.9
Donnelly, P.10
Altshuler, D.11
-
30
-
-
48449095981
-
Comparative Pathway Analyzer--a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms
-
10.1093/nar/gkn284, 2447754, 18539612
-
Oehm S, Gilbert D, Tauch A, Stoye J, Goesmann A. Comparative Pathway Analyzer--a web server for comparative analysis, clustering and visualization of metabolic networks in multiple organisms. Nucleic Acids Res 2008, 36:W433-7. 10.1093/nar/gkn284, 2447754, 18539612.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Oehm, S.1
Gilbert, D.2
Tauch, A.3
Stoye, J.4
Goesmann, A.5
-
31
-
-
0033982936
-
KEGG: kyoto encyclopedia of genes and genomes
-
10.1093/nar/28.1.27, 102409, 10592173
-
Kanehisa M, Goto S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 2000, 28:27-30. 10.1093/nar/28.1.27, 102409, 10592173.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 27-30
-
-
Kanehisa, M.1
Goto, S.2
-
32
-
-
0842312531
-
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
-
10.1097/00008571-200401000-00001, 15128046
-
Nelson DR, Zeldin DC, Hoffman SMG, Maltais LJ, Wain HM, Nebert DW. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics 2004, 14:1-18. 10.1097/00008571-200401000-00001, 15128046.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 1-18
-
-
Nelson, D.R.1
Zeldin, D.C.2
Hoffman, S.M.G.3
Maltais, L.J.4
Wain, H.M.5
Nebert, D.W.6
-
33
-
-
33846056843
-
Entrez Gene: gene-centered information at NCBI
-
10.1093/nar/gkl993, 1761442, 17148475
-
Maglott D, Ostell J, Pruitt KD, Tatusova T. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res 2007, 35:D26-31. 10.1093/nar/gkl993, 1761442, 17148475.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Maglott, D.1
Ostell, J.2
Pruitt, K.D.3
Tatusova, T.4
-
34
-
-
63549108441
-
GrowMatch: an automated method for reconciling in silico/in vivo growth predictions
-
10.1371/journal.pcbi.1000308, 2645679, 19282964
-
Kumar VS, Maranas CD. GrowMatch: an automated method for reconciling in silico/in vivo growth predictions. PLoS Comput Biol 2009, 5:e1000308. 10.1371/journal.pcbi.1000308, 2645679, 19282964.
-
(2009)
PLoS Comput Biol
, vol.5
-
-
Kumar, V.S.1
Maranas, C.D.2
-
35
-
-
0025239015
-
Missense mutation (Gly----Glu188) of human lipoprotein lipase imparting functional deficiency
-
Emi M, Wilson DE, Iverius PH, Wu L, Hata A, Hegele R, Williams RR, Lalouel JM. Missense mutation (Gly----Glu188) of human lipoprotein lipase imparting functional deficiency. J Biol Chem 1990, 265:5910-5916.
-
(1990)
J Biol Chem
, vol.265
, pp. 5910-5916
-
-
Emi, M.1
Wilson, D.E.2
Iverius, P.H.3
Wu, L.4
Hata, A.5
Hegele, R.6
Williams, R.R.7
Lalouel, J.M.8
-
36
-
-
0033021054
-
Mutations in the lipoprotein lipase gene associated with ischemic heart disease in men. The Copenhagen city heart study
-
Wittrup HH, Tybjaerg-Hansen A, Steffensen R, Deeb SS, Brunzell JD, Jensen G, Nordestgaard BG. Mutations in the lipoprotein lipase gene associated with ischemic heart disease in men. The Copenhagen city heart study. Arterioscler Thromb Vasc Biol 1999, 19:1535-1540.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 1535-1540
-
-
Wittrup, H.H.1
Tybjaerg-Hansen, A.2
Steffensen, R.3
Deeb, S.S.4
Brunzell, J.D.5
Jensen, G.6
Nordestgaard, B.G.7
-
37
-
-
0028819754
-
Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes
-
10.1172/JCI118319, 185959, 8675619
-
Weinstock PH, Bisgaier CL, Aalto-Setälä K, Radner H, Ramakrishnan R, Levak-Frank S, Essenburg AD, Zechner R, Breslow JL. Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest 1995, 96:2555-2568. 10.1172/JCI118319, 185959, 8675619.
-
(1995)
J Clin Invest
, vol.96
, pp. 2555-2568
-
-
Weinstock, P.H.1
Bisgaier, C.L.2
Aalto-Setälä, K.3
Radner, H.4
Ramakrishnan, R.5
Levak-Frank, S.6
Essenburg, A.D.7
Zechner, R.8
Breslow, J.L.9
-
38
-
-
70350618065
-
Developmental expression pattern of the cholesterogenic enzyme NSDHL and negative selection of NSDHL-deficient cells in the heterozygous Bpa(1H)/+ mouse
-
10.1016/j.ymgme.2009.06.016, 19631568
-
Cunningham D, Spychala K, McLarren KW, Garza LA, Boerkoel CF, Herman GE. Developmental expression pattern of the cholesterogenic enzyme NSDHL and negative selection of NSDHL-deficient cells in the heterozygous Bpa(1H)/+ mouse. Mol Genet Metab 2009, 98:356-366. 10.1016/j.ymgme.2009.06.016, 19631568.
-
(2009)
Mol Genet Metab
, vol.98
, pp. 356-366
-
-
Cunningham, D.1
Spychala, K.2
McLarren, K.W.3
Garza, L.A.4
Boerkoel, C.F.5
Herman, G.E.6
-
39
-
-
0036261663
-
Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development
-
10.1128/MCB.22.12.4158-4166.2002, 133862, 12024029
-
Di Pietro E, Sirois J, Tremblay ML, MacKenzie RE. Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development. Mol Cell Biol 2002, 22:4158-4166. 10.1128/MCB.22.12.4158-4166.2002, 133862, 12024029.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4158-4166
-
-
Di Pietro, E.1
Sirois, J.2
Tremblay, M.L.3
MacKenzie, R.E.4
-
40
-
-
27644537134
-
Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice
-
Hojjati MR, Li Z, Jiang X. Serine palmitoyl-CoA transferase (SPT) deficiency and sphingolipid levels in mice. Biochim Biophys Acta 2005, 1737:44-51.
-
(2005)
Biochim Biophys Acta
, vol.1737
, pp. 44-51
-
-
Hojjati, M.R.1
Li, Z.2
Jiang, X.3
-
41
-
-
0038036707
-
Surprising roles of electrostatic interactions in DNA-ligand complexes
-
10.1002/bip.10319, 12717724
-
Howerton SB, Nagpal A, Williams LD. Surprising roles of electrostatic interactions in DNA-ligand complexes. Biopolymers 2003, 69:87-99. 10.1002/bip.10319, 12717724.
-
(2003)
Biopolymers
, vol.69
, pp. 87-99
-
-
Howerton, S.B.1
Nagpal, A.2
Williams, L.D.3
-
42
-
-
33748594955
-
Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model
-
Huyghe S, Mannaerts GP, Baes M, Van Veldhoven PP. Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model. Biochim Biophys Acta 2006, 1761:973-994.
-
(2006)
Biochim Biophys Acta
, vol.1761
, pp. 973-994
-
-
Huyghe, S.1
Mannaerts, G.P.2
Baes, M.3
Van Veldhoven, P.P.4
-
43
-
-
10744228153
-
Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency
-
10.1093/hmg/ddg172, 12812989
-
Krakowiak PA, Wassif CA, Kratz L, Cozma D, Kovárová M, Harris G, Grinberg A, Yang Y, Hunter AGW, Tsokos M, Kelley RI, Porter FD. Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency. Hum Mol Genet 2003, 12:1631-1641. 10.1093/hmg/ddg172, 12812989.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1631-1641
-
-
Krakowiak, P.A.1
Wassif, C.A.2
Kratz, L.3
Cozma, D.4
Kovárová, M.5
Harris, G.6
Grinberg, A.7
Yang, Y.8
Hunter, A.G.W.9
Tsokos, M.10
Kelley, R.I.11
Porter, F.D.12
-
44
-
-
0035081263
-
Transgenic rescue of the tattered phenotype by using a BAC encoding Ebp
-
10.1007/s003350010262, 11309666
-
Means GD, Boyd Y, Willis CR, Derry JM. Transgenic rescue of the tattered phenotype by using a BAC encoding Ebp. Mamm Genome 2001, 12:323-325. 10.1007/s003350010262, 11309666.
-
(2001)
Mamm Genome
, vol.12
, pp. 323-325
-
-
Means, G.D.1
Boyd, Y.2
Willis, C.R.3
Derry, J.M.4
-
45
-
-
32844454617
-
DHCR24 gene knockout mice demonstrate lethal dermopathy with differentiation and maturation defects in the epidermis
-
10.1038/sj.jid.5700111, 16410790
-
Mirza R, Hayasaka S, Takagishi Y, Kambe F, Ohmori S, Maki K, Yamamoto M, Murakami K, Kaji T, Zadworny D, Murata Y, Seo H. DHCR24 gene knockout mice demonstrate lethal dermopathy with differentiation and maturation defects in the epidermis. J Invest Dermatol 2006, 126:638-647. 10.1038/sj.jid.5700111, 16410790.
-
(2006)
J Invest Dermatol
, vol.126
, pp. 638-647
-
-
Mirza, R.1
Hayasaka, S.2
Takagishi, Y.3
Kambe, F.4
Ohmori, S.5
Maki, K.6
Yamamoto, M.7
Murakami, K.8
Kaji, T.9
Zadworny, D.10
Murata, Y.11
Seo, H.12
-
46
-
-
28844440297
-
Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects
-
10.1074/jbc.M506510200, 2888304, 16192276
-
Steenbergen R, Nanowski TS, Beigneux A, Kulinski A, Young SG, Vance JE. Disruption of the phosphatidylserine decarboxylase gene in mice causes embryonic lethality and mitochondrial defects. J Biol Chem 2005, 280:40032-40040. 10.1074/jbc.M506510200, 2888304, 16192276.
-
(2005)
J Biol Chem
, vol.280
, pp. 40032-40040
-
-
Steenbergen, R.1
Nanowski, T.S.2
Beigneux, A.3
Kulinski, A.4
Young, S.G.5
Vance, J.E.6
-
47
-
-
0026948594
-
Expression of tyrosinase gene in transgenic albino mice: the heritable patterned coat colors
-
10.1111/j.1600-0749.1992.tb00553.x, 1292013
-
Tanaka S, Takeuchi T. Expression of tyrosinase gene in transgenic albino mice: the heritable patterned coat colors. Pigment Cell Res 1992, 5:300-303. 10.1111/j.1600-0749.1992.tb00553.x, 1292013.
-
(1992)
Pigment Cell Res
, vol.5
, pp. 300-303
-
-
Tanaka, S.1
Takeuchi, T.2
-
48
-
-
0032748583
-
Embryonic lethality and defective neural tube closure in mice lacking squalene synthase
-
10.1074/jbc.274.43.30843, 10521476
-
Tozawa R, Ishibashi S, Osuga J, Yagyu H, Oka T, Chen Z, Ohashi K, Perrey S, Shionoiri F, Yahagi N, Harada K, Gotoda T, Yazaki Y, Yamada N. Embryonic lethality and defective neural tube closure in mice lacking squalene synthase. J Biol Chem 1999, 274:30843-30848. 10.1074/jbc.274.43.30843, 10521476.
-
(1999)
J Biol Chem
, vol.274
, pp. 30843-30848
-
-
Tozawa, R.1
Ishibashi, S.2
Osuga, J.3
Yagyu, H.4
Oka, T.5
Chen, Z.6
Ohashi, K.7
Perrey, S.8
Shionoiri, F.9
Yahagi, N.10
Harada, K.11
Gotoda, T.12
Yazaki, Y.13
Yamada, N.14
-
49
-
-
0028937163
-
Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia
-
10.1073/pnas.92.5.1585, 42564, 7878023
-
Watanabe M, Osada J, Aratani Y, Kluckman K, Reddick R, Malinow MR, Maeda N. Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia. Proc Natl Acad Sci USA 1995, 92:1585-1589. 10.1073/pnas.92.5.1585, 42564, 7878023.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1585-1589
-
-
Watanabe, M.1
Osada, J.2
Aratani, Y.3
Kluckman, K.4
Reddick, R.5
Malinow, M.R.6
Maeda, N.7
-
50
-
-
9144270452
-
Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality
-
10.1074/jbc.C300507200, 14645240
-
Yoshida K, Furuya S, Osuka S, Mitoma J, Shinoda Y, Watanabe M, Azuma N, Tanaka H, Hashikawa T, Itohara S, Hirabayashi Y. Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality. J Biol Chem 2004, 279:3573-3577. 10.1074/jbc.C300507200, 14645240.
-
(2004)
J Biol Chem
, vol.279
, pp. 3573-3577
-
-
Yoshida, K.1
Furuya, S.2
Osuka, S.3
Mitoma, J.4
Shinoda, Y.5
Watanabe, M.6
Azuma, N.7
Tanaka, H.8
Hashikawa, T.9
Itohara, S.10
Hirabayashi, Y.11
-
51
-
-
18044377392
-
Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression
-
10.1016/j.devbrainres.2005.01.012, 15862627
-
Yu H, Wessels A, Tint GS, Patel SB. Partial rescue of neonatal lethality of Dhcr7 null mice by a nestin promoter-driven DHCR7 transgene expression. Brain Res Dev Brain Res 2005, 156:46-60. 10.1016/j.devbrainres.2005.01.012, 15862627.
-
(2005)
Brain Res Dev Brain Res
, vol.156
, pp. 46-60
-
-
Yu, H.1
Wessels, A.2
Tint, G.S.3
Patel, S.B.4
-
52
-
-
0027156355
-
Striking homology between mouse and human transcription enhancer factor-1 (TEF-1)
-
10.1093/nar/21.3.747, 309183, 8441689
-
Blatt C, DePamphilis ML. Striking homology between mouse and human transcription enhancer factor-1 (TEF-1). Nucleic Acids Res 1993, 21:747-748. 10.1093/nar/21.3.747, 309183, 8441689.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 747-748
-
-
Blatt, C.1
DePamphilis, M.L.2
-
53
-
-
0038609020
-
Examination of sequence homology between human chromosome 20 and the mouse genome: intense conservation of many genomic elements
-
Zhu L, Swergold GD, Seldin MF. Examination of sequence homology between human chromosome 20 and the mouse genome: intense conservation of many genomic elements. Hum Genet 2003, 113:60-70.
-
(2003)
Hum Genet
, vol.113
, pp. 60-70
-
-
Zhu, L.1
Swergold, G.D.2
Seldin, M.F.3
-
54
-
-
34447338048
-
Distribution of orphan metabolic activities
-
10.1016/j.tibtech.2007.06.001, 17580095
-
Chen L, Vitkup D. Distribution of orphan metabolic activities. Trends Biotechnol 2007, 25:343-348. 10.1016/j.tibtech.2007.06.001, 17580095.
-
(2007)
Trends Biotechnol
, vol.25
, pp. 343-348
-
-
Chen, L.1
Vitkup, D.2
-
55
-
-
33645895566
-
Orphan enzymes could be an unexplored reservoir of new drug targets
-
10.1016/j.drudis.2006.02.002, 16580971
-
Lespinet O, Labedan B. Orphan enzymes could be an unexplored reservoir of new drug targets. Drug Discov Today 2006, 11:300-305. 10.1016/j.drudis.2006.02.002, 16580971.
-
(2006)
Drug Discov Today
, vol.11
, pp. 300-305
-
-
Lespinet, O.1
Labedan, B.2
-
56
-
-
33846086384
-
Systems biology of SNPs
-
10.1038/msb4100077, 1681509, 16820779
-
Jamshidi N, Palsson B. Systems biology of SNPs. Mol Syst Biol 2006, 2:38. 10.1038/msb4100077, 1681509, 16820779.
-
(2006)
Mol Syst Biol
, vol.2
, pp. 38
-
-
Jamshidi, N.1
Palsson, B.2
-
57
-
-
66249132328
-
Predicting metabolic biomarkers of human inborn errors of metabolism
-
10.1038/msb.2009.22, 2683725, 19401675
-
Shlomi T, Cabili MN, Ruppin E. Predicting metabolic biomarkers of human inborn errors of metabolism. Mol Syst Biol 2009, 5:263. 10.1038/msb.2009.22, 2683725, 19401675.
-
(2009)
Mol Syst Biol
, vol.5
, pp. 263
-
-
Shlomi, T.1
Cabili, M.N.2
Ruppin, E.3
-
58
-
-
42349100173
-
The chemical genomic portrait of yeast: uncovering a phenotype for all genes
-
Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G. The chemical genomic portrait of yeast: uncovering a phenotype for all genes. Science (80-) 2008, 320:362-365.
-
(2008)
Science (80-)
, vol.320
, pp. 362-365
-
-
Hillenmeyer, M.E.1
Fung, E.2
Wildenhain, J.3
Pierce, S.E.4
Hoon, S.5
Lee, W.6
Proctor, M.7
St Onge, R.P.8
Tyers, M.9
Koller, D.10
Altman, R.B.11
Davis, R.W.12
Nislow, C.13
Giaever, G.14
-
59
-
-
0036215090
-
Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort
-
10.1007/s00335-001-4001-y, 11956758
-
Threadgill DW, Hunter KW, Williams RW. Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort. Mamm Genome 2002, 13:175-178. 10.1007/s00335-001-4001-y, 11956758.
-
(2002)
Mamm Genome
, vol.13
, pp. 175-178
-
-
Threadgill, D.W.1
Hunter, K.W.2
Williams, R.W.3
-
60
-
-
53749085229
-
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
-
10.1038/nbt1492, 18846089
-
Herrgård MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Blüthgen N, Borger S, Costenoble R, Heinemann M, Hucka M, Le Novère N, Li P, Liebermeister W, Mo ML, Oliveira AP, Petranovic D, Pettifer S, Simeonidis E, Smallbone K, Spasić I, Weichart D, Brent R, Broomhead DS, Westerhoff HV, Kirdar B, Penttilä M, Klipp E, Palsson B, Sauer U. A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nat Biotechnol 2008, 26:1155-1160. 10.1038/nbt1492, 18846089.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1155-1160
-
-
Herrgård, M.J.1
Swainston, N.2
Dobson, P.3
Dunn, W.B.4
Arga, K.Y.5
Arvas, M.6
Blüthgen, N.7
Borger, S.8
Costenoble, R.9
Heinemann, M.10
Hucka, M.11
Le Novère, N.12
Li, P.13
Liebermeister, W.14
Mo, M.L.15
Oliveira, A.P.16
Petranovic, D.17
Pettifer, S.18
Simeonidis, E.19
Smallbone, K.20
Spasić, I.21
Weichart, D.22
Brent, R.23
Broomhead, D.S.24
Westerhoff, H.V.25
Kirdar, B.26
Penttilä, M.27
Klipp, E.28
Palsson, B.29
Sauer, U.30
more..
-
61
-
-
40949136507
-
Increased expression of aquaporin-3 in the epidermis of DHCR24 knockout mice
-
10.1111/j.1365-2133.2007.08424.x, 18241265
-
Mirza R, Hayasaka S, Kambe F, Maki K, Kaji T, Murata Y, Seo H. Increased expression of aquaporin-3 in the epidermis of DHCR24 knockout mice. Br J Dermatol 2008, 158:679-684. 10.1111/j.1365-2133.2007.08424.x, 18241265.
-
(2008)
Br J Dermatol
, vol.158
, pp. 679-684
-
-
Mirza, R.1
Hayasaka, S.2
Kambe, F.3
Maki, K.4
Kaji, T.5
Murata, Y.6
Seo, H.7
-
62
-
-
77749320898
-
What is flux balance analysis?
-
10.1038/nbt.1614, 20212490
-
Orth JD, Thiele I, Palsson B. What is flux balance analysis?. Nat Biotechnol 2010, 28:245-248. 10.1038/nbt.1614, 20212490.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 245-248
-
-
Orth, J.D.1
Thiele, I.2
Palsson, B.3
-
63
-
-
1642457253
-
The effects of alternate optimal solutions in constraint-based genome-scale metabolic models
-
10.1016/j.ymben.2003.09.002, 14642354
-
Mahadevan R, Schilling CH. The effects of alternate optimal solutions in constraint-based genome-scale metabolic models. Metab Eng 2003, 5:264-276. 10.1016/j.ymben.2003.09.002, 14642354.
-
(2003)
Metab Eng
, vol.5
, pp. 264-276
-
-
Mahadevan, R.1
Schilling, C.H.2
-
64
-
-
0035798406
-
Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure
-
10.1006/jmbi.2001.5080, 11697912
-
Gough J, Karplus K, Hughey R, Chothia C. Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure. J Mol Biol 2001, 313:903-919. 10.1006/jmbi.2001.5080, 11697912.
-
(2001)
J Mol Biol
, vol.313
, pp. 903-919
-
-
Gough, J.1
Karplus, K.2
Hughey, R.3
Chothia, C.4
-
65
-
-
65549092780
-
Use of randomized sampling for analysis of metabolic networks
-
10.1074/jbc.R800048200, 18940807
-
Schellenberger J, Palsson B. Use of randomized sampling for analysis of metabolic networks. J Biol Chem 2009, 284:5457-5461. 10.1074/jbc.R800048200, 18940807.
-
(2009)
J Biol Chem
, vol.284
, pp. 5457-5461
-
-
Schellenberger, J.1
Palsson, B.2
-
66
-
-
15844387127
-
Candidate metabolic network states in human mitochondria. Impact of diabetes, ischemia, and diet
-
10.1074/jbc.M409072200, 15572364
-
Thiele I, Price ND, Vo TD, Palsson B. Candidate metabolic network states in human mitochondria. Impact of diabetes, ischemia, and diet. J Biol Chem 2005, 280:11683-11695. 10.1074/jbc.M409072200, 15572364.
-
(2005)
J Biol Chem
, vol.280
, pp. 11683-11695
-
-
Thiele, I.1
Price, N.D.2
Vo, T.D.3
Palsson, B.4
|