HOPX hypermethylation promotes metastasis via activating SNAIL transcription in nasopharyngeal carcinoma

Nature Communications

Volumn 8, Issue , 2017, Pages

  Ren, Xianyue ^a,b   Yang, Xiaojing ^a   Cheng, Bin ^b   Chen, Xiaozhong ^c   Zhang, Tianpeng ^b   He, Qingmei ^a   Li, Bin ^c   Li, Yingqin ^a   Tang, Xinran ^a   Wen, Xin ^a   Zhong, Qian ^a   Kang, Tiebang ^a   Zeng, Musheng ^a   Liu, Na ^a   Ma, Jun ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c ZHEJIANG CANCER HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; CISPLATIN; FIBRONECTIN; HISTONE DEACETYLASE 2; HISTONE H3; HOP HOMEOBOX PROTEIN; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SNAIL; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; HISTONE; HOMEODOMAIN PROTEIN; HOP PROTEIN, HUMAN;

ABNORMALITY; BIOMARKER; CANCER; DISEASE TREATMENT; GENE EXPRESSION; GENETIC ANALYSIS; METHYLATION; PROTEIN; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER RESISTANCE; CANCER SURVIVAL; CANCER TISSUE; CHEMOSENSITIVITY; CLINICAL OUTCOME; COHORT ANALYSIS; CONTROLLED STUDY; DEACETYLATION; DISEASE FREE SURVIVAL; DISTANT METASTASIS FREE SURVIVAL; DNA METHYLATION; DOWN REGULATION; EPIGENETIC REPRESSION; EPIGENETICS; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; MOUSE; NASOPHARYNX CARCINOMA; NONHUMAN; OVERALL SURVIVAL; PROMOTER REGION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ACETYLATION; ANIMAL; BAGG ALBINO MOUSE; GENETICS; KAPLAN MEIER METHOD; METABOLISM; METASTASIS; NASOPHARYNX TUMOR; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; XENOGRAFT;

ACETYLATION; ANIMALS; CELL LINE, TUMOR; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; KAPLAN-MEIER ESTIMATE; MICE, INBRED BALB C; MICE, NUDE; NASOPHARYNGEAL NEOPLASMS; NEOPLASM METASTASIS; PROMOTER REGIONS, GENETIC; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSPLANTATION, HETEROLOGOUS; TUMOR SUPPRESSOR PROTEINS;

EID: 85011340647     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms14053     Document Type: Article

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