Upregulation of flotillin-1 promotes invasion and metastasis by activating TGF-β signaling in nasopharyngeal carcinoma

Oncotarget

Volumn 7, Issue 4, 2016, Pages 4252-4264

  Cao, Sumei ^a,b   Cui, Yanmei ^a   Xiao, Huiming ^c   Mai, Miaoqing ^b   Wang, Chanjuan ^d   Xie, Shanghang ^b   Yang, Jing ^b   Wu, Shu ^a   Li, Jun ^e   Song, Libing ^a   Guo, Xiang ^a,b   Lin, Chuyong ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^e SUN YAT SEN UNIVERSITY   (China)

Author keywords

Flotillin 1; Lymph node metastasis; Nasopharyngeal carcinoma; TGF signaling

Indexed keywords

FLOTILLIN 1; MESSENGER RNA; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; FLOTILLINS; MEMBRANE PROTEIN;

ARTICLE; CANCER CLASSIFICATION; CANCER GROWTH; CELL LINE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE FREE SURVIVAL; EPITHELIAL MESENCHYMAL TRANSITION; FLOT1 GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LIPID RAFT; LYMPH NODE METASTASIS; NASOPHARYNX CARCINOMA; NASOPHARYNX CARCINOMA CELL LINE; PROTEIN EXPRESSION; REGULATORY MECHANISM; TGFB1 GENE; TUMOR INVASION; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; CANCER STAGING; CELL MOTION; CELL PROLIFERATION; DRUG SCREENING; ENZYME IMMUNOASSAY; METABOLISM; MOUSE; NASOPHARYNX TUMOR; NUDE MOUSE; PATHOLOGY; PROGNOSIS; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHATIC METASTASIS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; NASOPHARYNGEAL NEOPLASMS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84958019490     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6483     Document Type: Article

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