메뉴 건너뛰기




Volumn 348, Issue 6242, 2015, Pages

Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; HOMEODOMAIN PROTEIN; HOPX PROTEIN; SMAD4 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; HOP PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

EID: 84933564630     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa6071     Document Type: Article
Times cited : (128)

References (40)
  • 1
    • 77958612344 scopus 로고    scopus 로고
    • Epstein Lecture. Cardiac development and implications for heart disease
    • pmid: 20961247
    • J. A. Epstein, Franklin H. Epstein Lecture. Cardiac development and implications for heart disease. N. Engl. J. Med. 363, 1638-1647 (2010). doi: 10.1056/NEJMra1003941; pmid: 20961247
    • (2010) N. Engl. J. Med. , vol.363 , pp. 1638-1647
    • Epstein, J.A.1    Franklin, H.2
  • 2
    • 0035461911 scopus 로고    scopus 로고
    • The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm
    • pmid: 11702954
    • R. G. Kelly, N. A. Brown, M. E. Buckingham, The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dev. Cell 1, 435-440 (2001). doi: 10.1016/S1534-5807(01)00040-5; pmid: 11702954
    • (2001) Dev. Cell , vol.1 , pp. 435-440
    • Kelly, R.G.1    Brown, N.A.2    Buckingham, M.E.3
  • 3
    • 0034839927 scopus 로고    scopus 로고
    • Conotruncal myocardium arises from a secondary heart field
    • pmid: 11688566
    • K. L. Waldo et al., Conotruncal myocardium arises from a secondary heart field. Development 128, 3179-3188 (2001). pmid: 11688566
    • (2001) Development , vol.128 , pp. 3179-3188
    • Waldo, K.L.1
  • 4
    • 0346783332 scopus 로고    scopus 로고
    • Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart
    • pmid: 14667410
    • C. L. Cai et al., Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev. Cell 5, 877-889 (2003). doi: 10.1016/S1534-5807(03)00363-0; pmid: 14667410
    • (2003) Dev. Cell , vol.5 , pp. 877-889
    • Cai, C.L.1
  • 5
    • 33750456216 scopus 로고    scopus 로고
    • Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages
    • pmid:17084363
    • S. J. Kattman, T. L. Huber, G. M. Keller, Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev. Cell 11, 723-732 (2006). doi: 10.1016/j.devcel.2006.10.002; pmid:17084363
    • (2006) Dev. Cell , vol.11 , pp. 723-732
    • Kattman, S.J.1    Huber, T.L.2    Keller, G.M.3
  • 6
    • 33845457194 scopus 로고    scopus 로고
    • Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification
    • pmid: 17123592
    • A. Moretti et al., Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127, 1151-1165 (2006). doi: 10.1016/j.cell.2006.10.029; pmid: 17123592
    • (2006) Cell , vol.127 , pp. 1151-1165
    • Moretti, A.1
  • 7
    • 33845442108 scopus 로고    scopus 로고
    • Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart
    • pmid: 17123591
    • S. M. Wu et al., Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 127, 1137-1150 (2006). doi: 10.1016/j.cell.2006.10.028; pmid: 17123591
    • (2006) Cell , vol.127 , pp. 1137-1150
    • Wu, S.M.1
  • 8
    • 33750936779 scopus 로고    scopus 로고
    • Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells
    • pmid: 17077151
    • P. Gadue, T. L. Huber, P. J. Paddison, G. M. Keller, Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 103, 16806-16811 (2006). doi: 10.1073/pnas.0603916103; pmid: 17077151
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 16806-16811
    • Gadue, P.1    Huber, T.L.2    Paddison, P.J.3    Keller, G.M.4
  • 9
    • 33845928762 scopus 로고    scopus 로고
    • Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis
    • pmid: 17170140
    • A. T. Naito et al., Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc. Natl. Acad. Sci. U.S.A. 103,19812-19817 (2006). pmid: 17170140
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 19812-19817
    • Naito, A.T.1
  • 10
    • 77955290927 scopus 로고    scopus 로고
    • Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells
    • pmid: 20559569
    • S. L. Paige et al., Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLOS ONE 5, e11134 (2010). doi: 10.1371/journal.pone.0011134; pmid: 20559569
    • (2010) PLOS ONE , vol.5
    • Paige, S.L.1
  • 11
    • 79551597211 scopus 로고    scopus 로고
    • Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
    • pmid: 21295278
    • S. J. Kattman et al., Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell 8, 228-240 (2011). doi: 10.1016/j.stem.2010.12.008; pmid: 21295278
    • (2011) Cell Stem Cell , vol.8 , pp. 228-240
    • Kattman, S.J.1
  • 12
    • 37549020639 scopus 로고    scopus 로고
    • Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood
    • M. C. Nostro, X. Cheng, G. M. Keller, P. Gadue, Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood. Cell Stem Cell 2, 60-71 (2008). doi: 10.1016/j.stem.2007.10.011;pmid:18371422
    • (2008) Cell Stem Cell , vol.2 , pp. 60-71
    • Nostro, M.C.1    Cheng, X.2    Keller, G.M.3    Gadue, P.4
  • 13
    • 84906899911 scopus 로고    scopus 로고
    • Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development
    • pmid: 25150979
    • F. Lescroart et al., Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development. Nat. Cell Biol. 16, 829-840 (2014). doi: 10.1038/ncb3024; pmid: 25150979
    • (2014) Nat. Cell Biol. , vol.16 , pp. 829-840
    • Lescroart, F.1
  • 14
    • 85016369664 scopus 로고    scopus 로고
    • Early patterning and specification of cardiac progenitors in gastrulating mesoderm
    • pmid:25296024
    • W. P. Devine, J. D. Wythe, M. George, K. Koshiba-Takeuchi, B. G. Bruneau, Early patterning and specification of cardiac progenitors in gastrulating mesoderm. eLife 3, e03848(2014).doi:10.7554/eLife.03848; pmid:25296024
    • (2014) eLife , vol.3
    • Devine, W.P.1    Wythe, J.D.2    George, M.3    Koshiba-Takeuchi, K.4    Bruneau, B.G.5
  • 15
    • 18644374460 scopus 로고    scopus 로고
    • Hop is an unusual homeobox gene that modulates cardiac development
    • pmid: 12297045
    • F. Chen et al., Hop is an unusual homeobox gene that modulates cardiac development. Cell 110, 713-723 (2002). doi: 10.1016/S0092-8674(02)00932-7; pmid: 12297045
    • (2002) Cell , vol.110 , pp. 713-723
    • Chen, F.1
  • 16
    • 44949262860 scopus 로고    scopus 로고
    • Regulation of survival in adult hippocampal and glioblastoma stem cell lineages by the homeodomain-only protein HOP
    • pmid: 18507846
    • A. De Toni et al., Regulation of survival in adult hippocampal and glioblastoma stem cell lineages by the homeodomain-only protein HOP. Neural Dev. 3, 13 (2008). doi: 10.1186/1749-8104-3-13; pmid: 18507846
    • (2008) Neural Dev. , vol.3 , pp. 13
    • De Toni, A.1
  • 17
    • 18644364557 scopus 로고    scopus 로고
    • Modulation of cardiac growth and development by HOP, an unusual homeodomain protein
    • pmid: 12297046
    • C. H. Shin et al., Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell 110, 725-735 (2002). doi: 10.1016/S0092-8674(02)00933-9; pmid: 12297046
    • (2002) Cell , vol.110 , pp. 725-735
    • Shin, C.H.1
  • 18
    • 84875475734 scopus 로고    scopus 로고
    • Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells
    • pmid: 23487314
    • N. Takeda et al., Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development 140, 1655-1664 (2013). doi: 10.1242/dev.093005; pmid: 23487314
    • (2013) Development , vol.140 , pp. 1655-1664
    • Takeda, N.1
  • 19
    • 83255193921 scopus 로고    scopus 로고
    • Interconversion between intestinal stem cell populations in distinct niches
    • pmid: 22075725
    • N. Takeda et al., Interconversion between intestinal stem cell populations in distinct niches. Science 334, 1420-1424 (2011). doi: 10.1126/science.1213214; pmid: 22075725
    • (2011) Science , vol.334 , pp. 1420-1424
    • Takeda, N.1
  • 20
    • 84855502585 scopus 로고    scopus 로고
    • Information on materials and methods is available on
    • Information on materials and methods is available on Science Online.
    • Science Online
  • 21
    • 40549132870 scopus 로고    scopus 로고
    • Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes
    • pmid: 18246200
    • N. Christoforou et al., Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes. J. Clin. Invest. 118, 894-903 (2008). pmid: 18246200
    • (2008) J. Clin. Invest. , vol.118 , pp. 894-903
    • Christoforou, N.1
  • 22
    • 33748369871 scopus 로고    scopus 로고
    • Analysis of the structure and function of the transcriptional coregulator HOP
    • pmid:16939210
    • H. Kook et al., Analysis of the structure and function of the transcriptional coregulator HOP. Biochemistry 45,10584-10590 (2006). doi: 10.1021/bi060641s; pmid:16939210
    • (2006) Biochemistry , vol.45 , pp. 10584-10590
    • Kook, H.1
  • 23
    • 34250888462 scopus 로고    scopus 로고
    • Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis
    • pmid:17519333
    • L. Lin et al., Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis. Proc. Natl. Acad. Sci. U.S.A. 104, 9313-9318 (2007). doi: 10.1073/pnas.0700923104;pmid:17519333
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 9313-9318
    • Lin, L.1
  • 24
    • 34447130140 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling
    • pmid: 17607356
    • E. D. Cohen et al., Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. J. Clin. Invest. 117, 1794-1804 (2007). doi: 10.1172/JCI31731; pmid: 17607356
    • (2007) J. Clin. Invest. , vol.117 , pp. 1794-1804
    • Cohen, E.D.1
  • 25
    • 84930661525 scopus 로고    scopus 로고
    • Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulation
    • pmid:25522363
    • E. Cagavi et al., Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulation. PLOS ONE 9, e110752 (2014). doi: 10.1371/journal.pone.0110752; pmid:25522363
    • (2014) PLOS ONE , vol.9
    • Cagavi, E.1
  • 26
    • 84926458172 scopus 로고    scopus 로고
    • Enhancing human cardiomyocyte differentiation from induced pluripotent stem cells with trichostatin A
    • pmid: 25520285
    • S. Y. Lim et al., Enhancing human cardiomyocyte differentiation from induced pluripotent stem cells with trichostatin A. Methods Mol. Biol. (2014). pmid: 25520285
    • (2014) Methods Mol. Biol.
    • Lim, S.Y.1
  • 27
    • 34250802982 scopus 로고    scopus 로고
    • Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells
    • pmid: 17522258
    • S. Ueno et al., Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 104, 9685-9690 (2007). doi: 10.1073/pnas.0702859104; pmid: 17522258
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 9685-9690
    • Ueno, S.1
  • 28
    • 6944224156 scopus 로고    scopus 로고
    • BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling
    • pmid: 15378062
    • X. C. He et al., BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat. Genet. 36, 1117-1121 (2004). doi: 10.1038/ng1430; pmid: 15378062
    • (2004) Nat. Genet. , vol.36 , pp. 1117-1121
    • He, X.C.1
  • 29
    • 84872832153 scopus 로고    scopus 로고
    • Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation
    • pmid: 23292934
    • E. Kandyba et al., Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. Proc. Natl. Acad. Sci. U.S.A. 110, 1351-1356 (2013). doi: 10.1073/pnas.1121312110; pmid: 23292934
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 1351-1356
    • Kandyba, E.1
  • 30
    • 38349098468 scopus 로고    scopus 로고
    • Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration
    • pmid: 18202659
    • M. V. Plikus et al., Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature 451, 340-344 (2008). doi: 10.1038/nature06457; pmid: 18202659
    • (2008) Nature , vol.451 , pp. 340-344
    • Plikus, M.V.1
  • 31
    • 84901020400 scopus 로고    scopus 로고
    • Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells
    • pmid:24808138
    • J. Song et al., Smad1 transcription factor integrates BMP2 and Wnt3a signals in migrating cardiac progenitor cells. Proc. Natl. Acad. Sci. U.S.A. 111, 7337-7342 (2014). doi: 10.1073/pnas.1321764111; pmid:24808138
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 7337-7342
    • Song, J.1
  • 32
    • 84881661799 scopus 로고    scopus 로고
    • HCN4 dynamically marks the first heart field and conduction system precursors
    • pmid: 23743334
    • X. Liang et al., HCN4 dynamically marks the first heart field and conduction system precursors. Circ. Res. 113, 399-407 (2013). doi: 10.1161/CIRCRESAHA.113.301588; pmid: 23743334
    • (2013) Circ. Res. , vol.113 , pp. 399-407
    • Liang, X.1
  • 33
    • 84883740296 scopus 로고    scopus 로고
    • A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells
    • pmid: 23974038
    • D. Später et al., A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells. Nat. Cell Biol. 15, 1098-1106 (2013). doi: 10.1038/ncb2824; pmid: 23974038
    • (2013) Nat. Cell Biol. , vol.15 , pp. 1098-1106
    • Später, D.1
  • 34
    • 84902312015 scopus 로고    scopus 로고
    • Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
    • pmid: 24776797
    • J. J. Chong et al., Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature 510, 273-277 (2014). doi: 10.1038/nature13233; pmid: 24776797
    • (2014) Nature , vol.510 , pp. 273-277
    • Chong, J.J.1
  • 35
    • 84922742836 scopus 로고    scopus 로고
    • BMP signaling and its pSMAD1/5 target genes differentially regulate hair follicle stem cell lineages
    • pmid: 25312496
    • M. Genander et al., BMP signaling and its pSMAD1/5 target genes differentially regulate hair follicle stem cell lineages. Cell Stem Cell 15, 619-633 (2014). doi: 10.1016/j.stem.2014.09.009; pmid: 25312496
    • (2014) Cell Stem Cell , vol.15 , pp. 619-633
    • Genander, M.1
  • 36
    • 84922542256 scopus 로고    scopus 로고
    • Single-cell analysis of proxy reporter allele-marked epithelial cells establishes intestinal stem cell hierarchy
    • pmid: 25418730
    • N. Li et al., Single-cell analysis of proxy reporter allele-marked epithelial cells establishes intestinal stem cell hierarchy. Stem Cell Rep. 3, 876-891 (2014). doi: 10.1016/j.stemcr.2014.09.011; pmid: 25418730
    • (2014) Stem Cell Rep. , vol.3 , pp. 876-891
    • Li, N.1
  • 37
    • 84878990582 scopus 로고    scopus 로고
    • Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis
    • pmid: 23707782
    • W. K. Cheung et al., Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis. Cancer Cell 23, 725-738 (2013). doi: 10.1016/j.ccr.2013.04.009; pmid: 23707782
    • (2013) Cancer Cell , vol.23 , pp. 725-738
    • Cheung, W.K.1
  • 38
    • 84888327294 scopus 로고    scopus 로고
    • The homeobox only protein homeobox (HOPX) and colorectal cancer
    • pmid: 24287901
    • K. Yamashita, H. Katoh, M. Watanabe, The homeobox only protein homeobox (HOPX) and colorectal cancer. Int. J. Mol. Sci. 14, 23231-23243 (2013). doi: 10.3390/ijms141223231; pmid: 24287901
    • (2013) Int. J. Mol. Sci. , vol.14 , pp. 23231-23243
    • Yamashita, K.1    Katoh, H.2    Watanabe, M.3
  • 39
    • 84872491549 scopus 로고    scopus 로고
    • Developmental signaling pathways in cancer stem cells of solid tumors
    • pmid: 23196196
    • C. Karamboulas, L. Ailles, Developmental signaling pathways in cancer stem cells of solid tumors. Biochim. Biophys. Acta 1830, 2481-2495 (2013). doi: 10.1016/j.bbagen.2012.11.008; pmid: 23196196
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 2481-2495
    • Karamboulas, C.1    Ailles, L.2
  • 40
    • 84855686613 scopus 로고    scopus 로고
    • A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis
    • pmid: 22234613
    • D. J. O'Connell et al., A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis. Sci. Signal. 5, ra4 (2012).pmid: 22234613
    • (2012) Sci. Signal. , vol.5 , pp. ra4
    • O'Connell, D.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.