STAT6 inhibitory peptide given during RSV infection of neonatal mice reduces exacerbated airway responses upon adult reinfection

Journal of Leukocyte Biology

Volumn 101, Issue 2, 2017, Pages 519-529

  Srinivasa, Bharat T ^a   Restori, Katherine H ^a   Shan, Jichuan ^b   Cyr, Louis ^a   Xing, Li ^a   Lee, Soojin ^b   Ward, Brian J ^a   Fixman, Elizabeth D ^b  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Alternatively activated macrophages; Asthma; Collagen deposition; Eosinophils; Hyperresponsiveness

Indexed keywords

CELL PENETRATING PEPTIDE; COLLAGEN; INTERLEUKIN 4; STAT6 INHIBITORY PEPTIDE; STAT6 PROTEIN; UNCLASSIFIED DRUG; CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 33; PEPTIDE; THYMIC STROMAL LYMPHOPOIETIN;

ADULT; AIRWAY; ALTERNATIVELY ACTIVATED MACROPHAGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; HUMAN; HUMAN CELL; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IN VITRO STUDY; IN VIVO STUDY; LOEFFLER PNEUMONIA; LUNG; MACROPHAGE ACTIVATION; MALE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REINFECTION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT ALLERGY; RISK REDUCTION; TH2 CELL; VIRUS PATHOGENESIS; VIRUS STRAIN; AGING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL COUNT; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; LYMPH NODE; METABOLISM; PATHOLOGY; TIME FACTOR; VIROLOGY;

AGING; ANIMALS; ANIMALS, NEWBORN; CELL COUNT; COLLAGEN; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INTERLEUKIN-17; INTERLEUKIN-33; LUNG; LYMPH NODES; MACROPHAGE ACTIVATION; MALE; MICE, INBRED BALB C; PEPTIDES; RESPIRATORY HYPERSENSITIVITY; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; STAT6 TRANSCRIPTION FACTOR; TIME FACTORS;

EID: 85011321033     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.4A0215-062RR     Document Type: Article

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