Flurbiprofen-loaded niosomes-in-gel system improves the ocular bioavailability of flurbiprofen in the aqueous humor

Drug Development and Industrial Pharmacy

Volumn 43, Issue 6, 2017, Pages 902-910

  El Sayed, Marwa M ^a   Hussein, Amal K ^a   Sarhan, Hatem A ^a   Mansour, Heba F ^a  

^a Minia University   (Egypt)

Author keywords

anti inflammatory; carbopol; carrageenan; flurbiprofen; Niosomes; pharmacokinetic parameters

Indexed keywords

CARBOMER; FLURBIPROFEN; NIOSOME; SORBITAN STEARATE; GEL; LIPOSOME; NONSTEROID ANTIINFLAMMATORY AGENT;

ALBINO RABBIT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AQUEOUS HUMOR; AREA UNDER THE CURVE; ARTICLE; CARRAGEENAN-INDUCED INFLAMMATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG TISSUE LEVEL; EYE INFLAMMATION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY POWDER DIFFRACTION; ANIMAL; BIOAVAILABILITY; GEL; INTRAOCULAR DRUG ADMINISTRATION; METABOLISM; RABBITS AND HARES; X RAY DIFFRACTION;

ADMINISTRATION, OPHTHALMIC; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AQUEOUS HUMOR; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG COMPOUNDING; FLURBIPROFEN; GELS; INJECTIONS, INTRAOCULAR; LIPOSOMES; MALE; PARTICLE SIZE; RABBITS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY DIFFRACTION;

EID: 85011290592     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639045.2016.1272120     Document Type: Article

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