Simple rapid validated RP-LC method for the estimation of flurbiprofen in rabbit serum and aqueous humor

Analytical Letters

Volumn 41, Issue 8, 2008, Pages 1318-1334

  Chandran, Sajeev ^a   Saha, Ranendra N ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Flurbiprofen; Rabbit aqueous humor; Rabbit serum; RP LC method

Indexed keywords

ORYCTOLAGUS CUNICULUS;

EID: 47249113904     PISSN: 00032719     EISSN: 1532236X     Source Type: Journal    
DOI: 10.1080/00032710802119137     Document Type: Article

References (33)

1. Albert, K.S., Gillespie, W.R., Raabe, A., and Garry, M. 1984. Determination of flurbiprofen in human serum by reverse-phase high-performance liquid chromatography with fluorescence detection. J. Pharm. Sci., 73 (12): 1823-1825.
2. Appiotti, A., Gualdi, L., Alberti, M., and Gualdi, M. 1998. Comparative study of the analgesic efficacy of flurbiprofen and diclofenac in patients following excimer laser photorefractive keratectomy. Clin. Ther., 20 (5): 913-920.
3. Askholt, J. and Nielsen-Kudsk, F. 1986. Rapid HPLC-determination of ibuprofen and flurbiprofen in plasma for therapeutic drug control and pharmacokinetic applications. Acta. Pharmacol. Toxicol. (Copenh.), 59 (5): 382-386.
4. Beaulieu, N., Cyr, T.D., and Lovering, E.G. 1991. Validation of methods for the assay of flurbiprofen and flurbiprofen sodium, related compounds and volatile impurities in raw materials and tablets. Drug Dev. Ind. Pharm., 17 (13): 1843-1855.
5. Bolton, S. 1997. Pharmaceutical Statistics: Practical and Clinical Application, 3rd ed. New York: Marcel Dekker.
6. Brägger, U., Mühle, T., Fourmousis, I., Lang, N.P., and Mombelli, A. 1997. Effect of the NSAID flurbiprofen on remodelling after periodontal surgery. J. Periodontal Res., 32 (7): 575-582.
7. British Pharmacoepia (BP). 1998. London: British Pharmacoepia Commission, pp. 612-613.
8. Diestelhorst, M., Schmidl, B., Konen, W., Mester, U., and Raj, P.S. 1996. Efficacy and tolerance ofdiclofenac sodium 0.1%, flurbiprofen 0.03%, and indomethacin 1.0% in controlling postoperative inflammation. J. Cataract Refract. Surg., 22 (Suppl. 1): 788-793.
9. Geisslinger, G., Menzel-Soglowek, S., Schuster, O., and Brune, K. 1992. Stereo-selective high-performance liquid chromatographic determination of flurbiprofen inhuman plasma. J. Chromatogr., 573 (1): 163-167.
10. Giagoudakis, G. and Markantonis, S.L. 1998. An alternative high-performance liquid-chromatographic method for the determination of diclofenac and flurbiprofen in plasma. J. Pharm. Biomed. Anal., 17: 897-901.
11. Hirai, T., Matsumoto, S., and Kishi, I. 1997. Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction. J. Chromatogr. B: Biomed. Sci. Appl., 692 (2): 375-388.
12. Hofer, M., Pospfsil, M., and Pipalova, I. 1996. Radioprotective effects of flurbiprofen. Folia Biol. (Praha), 42: 267-269.
13. Hutzler, J.M., Fyre, R.F., and Tracy, T.S. 2000. Sensitive and specific high-performance liquid chromatographic assay for 4′-hydroxyflurbiprofen and flurbiprofen in human urine and plasma. J. Chromatogr. B: Biomed. Sci. Appl., 749 (1): 119-125.
14. Indian Pharmacoepia (IP). 1996. New Delhi: Indian Pharmacoepial Commission, pp. 328-329.
15. International Conference on Harmonisation (ICH). 1996. Technical Requirements for Registration of Pharmaceuticals for Human Use: Harmonised Tripartite Guideline on Validation of Analytical Procedures: Methodology. Switzerland: Recommended for adoption at Step 4 of the ICH Process, by the ICH Steering Committee. IFPMA.
16. Johnson, V.A. and Wilson, J.T. 1986. Flurbiprofen analysis in plasma and breast milk by high-performance liquid chromatography. J. Chromatogr. B: Biomed. Sci. Appl., 382: 372-376.
17. Jones, D.S., Irwin, C.R., Woolfson, A.D., Djokic, J., and Adams, V. 1999. Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis. J. Pharm. Sci., 88 (6): 592-598.
18. Juchelková, L., Hofer, M., Pospísil, M., and Pipalová, I. 1998. Radioprotective effects of flurbiprofen and its nitroderivative. Physiol. Res., 47 (1): 73-80.
19. Knadler, M.P. and Hall, S.D. 1989. High-performance liquid chromatographic analysis of the enantiomers of flurbiprofen and its metabolites in plasma and urine. J. Chromatogr. B: Biomed. Sci. Appl., 494: 173-182.
20. Mathew, M., Gupta, V.D., and Bethea, C. 1993. Quantitation of flurbiprofen in tablets using high performance liquid chromatography. Drug Dev. Ind. Pharm., 19 (4): 493-498.
21. McCracken, J.D., Wechter, W.J., Liu, Y., Chase, R.L., Kantoci, D., Murray, E.D., Jr., Quiggle, D.D., and Mineyama, Y. 1996. Antiproliferative effects of the enantiomers of flurbiprofen. J. Clin. Pharmacol., 36 (6): 540-545.
22. Pe'hourcq, F., Jarry, C., Bannwarth, B. 2001.Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase. Biomed. Chromatogr., 15: 217-222.
23. Riegel, M. and Ellis, P.P. 1994. High-performance liquid chromatographic assay for anti-inflammatory agents diclofenac and flurbiprofen in ocular fluids. J. Chromatogr. B: Biomed. Sci. Appl., 654 (1): 140-145.
24. Sajeev, C., Jadhav, P.R., Ravishankar, D., and Saha R.N. 2002. Determination of flurbiprofen in pharmaceutical dosage form by UV spectrophotometry and LC. Analytica Chimica Acta, 463 (2): 207-217.
25. Shah, V.P., Midha, K.K., Dighe, S., McGilveray, I.J., Skelly, J.P., Yacobi, A., Layoff, T., Vishwanathan, C.T., Cork, C.E., McDowall, R.D., Pitman, K.A., and Spector, S. 1992. Analytical methods validation: Bioavailability, bioequivalence and pharmacokinetic studies. Pharm. Res., 9: 588-592.
26. Snider, B.G., Beaubien, L.J., Sears, D.J., and Rahn, P.D. 1981. Determination of flurbiprofen and ibuprofen in dog serum with automated sample preparation. J. Pharm. Sci., 70 (12): 1347-1349.
27. Soulier, S.M., Page, J.C., Larsen, L.C., and Grose, B.C. 1997. The efficacy of ANSAID (flurbiprofen) as an analgesic in foot surgery. J. Foot Ankle Surg., 36 (6): 414-417.
28. Sud, R.N., Greval, R.S., and Bajwa, R.S. 1995. Topical flurbiprofen therapy in vernal keratoconjunctivitis. Indian J. Med. Sci., 49 (9): 205-209.
29. Tang-Liu, D.D-S., Liu, S.S., and Weinkam, R.J. 1984. Ocular and systemic bioavailability of ophthalmic flurbiprofen. J. Pharmacokinet. Biopharm., 12: 611-626.
30. Teng, X.W., Wang, S.W.J., and Davies, N.M. 2003. Stereospecific high-performance liquid chromatographic analysis of flurbiprofen: Application to pharmacokinetic studies. J. Pharm. Biomed. Anal., 33 (1): 95-100.
31. rd ed. Rockville, MD: United States Pharmacoepial Convention, pp. 748-750.
32. United States Pharmacoepia (USP), XXVI. 2003. Validation of Compendial Methods, 26th ed. Rockville, MD: United States Pharmacoepial Convention, pp. 2439-2442.
33. Vajpayee, R.B., Dhakal, B.P., Gupta, S.K., Sachdev, M.S., Satpathy, G., Honavar, S.G., and Panda, A. 1996. Evaluation of topical 0.03% flurbiprofen drops in the treatment of herpetic stromal keratitis. Aust. N. Z. J. Ophthalmol., 24 (2): 131-135.