Enhancement of lomefloxacin Hcl ocular efficacy via niosomal encapsulation: in vitro characterization and in vivo evaluation

Journal of Liposome Research

Volumn 27, Issue 4, 2017, Pages 312-323

  Khalil, Rawia M ^a   Abdelbary, Ghada A ^b   Basha, Mona ^a   Awad, Ghada E A ^a   el Hashemy, Hadeer A ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Conjunctivitis; lomefloxacin Hcl; microbiological evaluation; niosomes; ocular delivery

Indexed keywords

CHOLESTEROL; LOMEFLOXACIN; NIOSOME; ORCHACIN; SURFACTANT; ANTIINFECTIVE AGENT; DRUG CARRIER; LIPOSOME; QUINOLONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BACTERIAL CONJUNCTIVITIS; CLINICAL OBSERVATION; CONJUNCTIVITIS; DEPENDENT VARIABLE; DISPERSION; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; ENCAPSULATION; HYDRATION; IN VITRO STUDY; IN VIVO STUDY; INDEPENDENT VARIABLE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; SUSTAINED DRUG RELEASE; TOPICAL TREATMENT; TREATMENT RESPONSE; ZETA POTENTIAL; ANIMAL; CHEMISTRY; DRUG EFFECT; DRUG RELEASE; DRUG STABILITY; EYE; HUMAN; LEPORIDAE; MALE; MEDICINAL CHEMISTRY; MICROBIOLOGY; PH; PROCEDURES; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; CHOLESTEROL; CONJUNCTIVITIS, BACTERIAL; DRUG CARRIERS; DRUG LIBERATION; DRUG STABILITY; EYE; FLUOROQUINOLONES; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; PARTICLE SIZE; RABBITS; STAPHYLOCOCCUS AUREUS; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS;

EID: 84976545295     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.1080/08982104.2016.1191022     Document Type: Article

References (72)

1. Abdallah M, Sammour O, El-Ghamry H, Abu-Selem M., (2013). Preparation and in-vitro evaluation of diclofenac sodium niosomal formulations. Int J Pharm Sci Res 4:1757–65
2. Abdelbary AA, Aboughaly MH., (2015). Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: application of Box–Behnken design, in-vitro evaluation and in-vivo skin deposition study. Int J Pharm 485:235–43
3. Abdelbary G., (2011). Ocular ciprofloxacin hydrochloride mucoadhesive chitosan-coated liposomes. Pharm Dev Technol 16:44–56
4. Abdelbary G, El-Gendy N., (2008). Niosome-encapsulated gentamicin for ophthalmic controlled delivery. AAPS PharmSciTech 9:740–7
5. Abdelbary GA, Aburahma MH., (2014). Oro-dental mucoadhesive proniosomal gel formulation loaded with lornoxicam for management of dental pain. J Liposome Res 24:1–15
6. Abdelkader H, Ismail S, Kamal A, Alany RG., (2011). Design and evaluation of controlled-release niosomes and discomes for naltrexone hydrochloride ocular delivery. J Pharm Sci 100:1833–46
7. Abdelkader H, Wu Z, Al-Kassas R, Alany RG., (2012). Niosomes and discomes for ocular delivery of naltrexone hydrochloride: morphological, rheological, spreading properties and photo-protective effects. Int J Pharm 433:142–8
8. Abu Hashim II, El-Dahan MS, Yusif RM, et al. (2014). Potential use of niosomal hydrogel as an ocular delivery system for atenolol. Biol Pharm Bull 37:541–51
9. Agarwal R, Katare OP, Vyas SP., (2001). Preparation and in vitro evaluation of liposomal/niosomal delivery systems for antipsoriatic drug dithranol. Int J Pharm 228:43–52
10. Aldred KJ, Kerns RJ, Osheroff N., (2014). Mechanism of quinolone action and resistance. Biochemistry 53:1565–74
11. Ambati J, Gragoudas ES, Miller JW, et al. (2000). Transscleral delivery of bioactive protein to the choroid and retina. Invest Ophthalmol Vis Sci 41:1186–91
12. Ammar HO, Salama HA, Ghorab M, Mahmoud AA., (2009). Nanoemulsion as a potential ophthalmic delivery system for dorzolamide hydrochloride. AAPS PharmSciTech 10:808–19
13. Araujo J, Gonzalez E, Egea MA, et al. (2009). Nanomedicines for ocular NSAIDs: safety on drug delivery. Nanomedicine 5:394–401
14. Attia SM., (2008). Abatement by naringin of lomefloxacin-induced genomic instability in mice. Mutagenesis 23:515–21
15. Basalious EB, Shawky N, Badr-Eldin SM., (2010). SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: development and optimization. Int J Pharm 391:203–11
16. Basha M, Abd El-Alim SH, Shamma RN, Awad GE., (2013). Design and optimization of surfactant-based nanovesicles for ocular delivery of Clotrimazole. J Liposome Res 23:203–10
17. Bayindir ZS, Yuksel N., (2010). Characterization of niosomes prepared with various nonionic surfactants for paclitaxel oral delivery. J Pharm Sci 99:2049–60
18. Beberok A, Otreba M, Wrzesniok D, Buszman E., (2013). Cytotoxic effect of lomefloxacin in culture of human epidermal melanocytes. Pharmacol Rep 65:689–99
19. Comstock TL, Karpecki PM, Morris TW, Zhang JZ., (2010). Besifloxacin: a novel anti-infective for the treatment of bacterial conjunctivitis. Clin Ophthalmol 4:215–25
20. Dharashivkar SS, Sahasrabuddhe SH, Saoji AN., (2014). Niosomally encapsulated silver sulfadiazine gel for burn treatment. J Microencapsul 32:1–6
21. Diebold Y, Calonge M., (2010). Applications of nanoparticles in ophthalmology. Prog Retin Eye Res 29:596–609
22. Dong Y, Dong P, Huang D, et al. (2015). Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery. Eur J Pharm Biopharm 91:82–90
23. Drlica K, Malik M., (2003). Fluoroquinolones: action and resistance. Curr Top Med Chem 3:249–82
24. Du Plessis J, Ramachandranb C, Weinerb N, Müllera DG., (1996). The influence of lipid composition and lamellarity of liposomes on the physical stability of liposomes upon storage. Int J Pharm 127:273–8
25. Fangueiro JF, Andreani T, Egea MA, et al. (2014). Design of cationic lipid nanoparticles for ocular delivery: development, characterization and cytotoxicity. Int J Pharm 461:64–73
26. Girigoswami A, Das S, De S., (2006). Fluorescence and dynamic light scattering studies of niosomes-membrane mimetic systems. Spectrochim Acta A Mol Biomol Spectrosc 64:859–66
27. Guinedi AS, Mortada ND, Mansour S, Hathout RM., (2005). Preparation and evaluation of reverse-phase evaporation and multilamellar niosomes as ophthalmic carriers of acetazolamide. Int J Pharm 306:71–82
28. Heurtault B, Saulnier P, Pech B, et al. (2003). Physico-chemical stability of colloidal lipid particles. Biomaterials 24:4283–300
29. Jadon PS, Gajbhiye V, Jadon RS, et al. (2009). Enhanced oral bioavailability of griseofulvin via niosomes. AAPS PharmSciTech 10:1186–92
30. Jin Y, Wen J, Garg S, et al. (2013). Development of a novel niosomal system for oral delivery of Ginkgo biloba extract. Int J Nanomedicine 8:421–30
31. Junyaprasert VB, Teeranachaideekul V, Supaperm T., (2008). Effect of charged and non-ionic membrane additives on physicochemical properties and stability of niosomes. AAPS PharmSciTech 9:851–9
32. Kakkar S, Kaur IP., (2011). Spanlastics-a novel nanovesicular carrier system for ocular delivery. Int J Pharm 413:202–10
33. Kamboj S, Saini V, Bala S., (2014). Formulation and characterization of drug loaded nonionic surfactant vesicles (niosomes) for oral bioavailability enhancement. ScientificWorldJournal. 2014:959741
34. Kamel R, Basha M, Abd El-Alim SH., (2013). Development of a novel vesicular system using a binary mixture of sorbitan monostearate and polyethylene glycol fatty acid esters for rectal delivery of rutin. J Liposome Res 23:28–36
35. Kaur IP, Aggarwal D, Singh H, Kakkar S., (2010). Improved ocular absorption kinetics of timolol maleate loaded into a bioadhesive niosomal delivery system. Graefes Arch Clin Exp Ophthalmol 248:1467–72
36. Kaur IP, Garg A, Singla AK, Aggarwal D., (2004). Vesicular systems in ocular drug delivery: an overview. Int J Pharm 269:1–14
37. Kayser O, Lemke A, Hernandez-Trejo N., (2005). The impact of nanobiotechnology on the development of new drug delivery systems. Curr Pharm Biotechnol 6:3–5
38. Klajnert B, Janiszewska J, Urbanczyk-Lipkowska Z, et al. (2006). DSC studies on interactions between low molecular mass peptide dendrimers and model lipid membranes. Int J Pharm 327:145–52
39. Kompella UB, Amrite AC, Pacha Ravi R, Durazo SA., (2013). Nanomedicines for back of the eye drug delivery, gene delivery, and imaging. Prog Retin Eye Res 36:172–98
40. Krustev SZ, Rusenova NV, Haritova AM., (2013). Effect of diclofenac on ocular levels of ciprofloxacin and lomefloxacin in rabbits with endophthalmitis. Drug Dev Ind Pharm 40:1459–1462
41. Kumar R, Sinha VR., (2014). Preparation and optimization of voriconazole microemulsion for ocular delivery. Colloids Surf B Biointerfaces 117:82–8
42. Li X, Zhang Z, Li J, et al. (2012). Diclofenac/biodegradable polymer micelles for ocular applications. Nanoscale 4:4667–73
43. Maiti S, Paul S, Mondol R, et al. (2011). Nanovesicular formulation of brimonidine tartrate for the management of glaucoma: in vitro and in vivo evaluation. AAPS PharmSciTech 12:755–63
44. Manosroi A, Khanrin P, Lohcharoenkal W, et al. (2010). Transdermal absorption enhancement through rat skin of gallidermin loaded in niosomes. Int J Pharm 392:304–10
45. Manosroi A, Podjanasoonthon K, Manosroi J., (2002). Development of novel topical tranexamic acid liposome formulations. Int J Pharm 235:61–70
46. Manosroia A, Wongtrakul P, Manosroi J, et al. (2003). Characterization of vesicles prepared with various non-ionic surfactants mixed with cholesterol. Colloids Surf B Biointerfaces 30:129–138
47. Moghassemi S, Hadjizadeh A., (2014). Nano-niosomes as nanoscale drug delivery systems: an illustrated review. J Control Release 185:22–36
48. Moghassemi S, Parnian E, Hakamivala A, et al. (2015). Uptake and transport of insulin across intestinal membrane model using trimethyl chitosan coated insulin niosomes. Mater Sci Eng C Mater Biol Appl 46:333–40
49. Moribe K, Maruyama K, Iwatsuru M., (1999). Encapsulation characteristics of nystatin in liposomes: effects of cholesterol and polyethylene glycol derivatives. Int J Pharm 188:193–202
50. Muzzalupo R, Trombino S, Iemma F, et al. (2005). Preparation and characterization of bolaform surfactant vesicles. Colloids Surf B Biointerfaces 46:78–83
51. Nagarwal RC, Kant S, Singh PN, et al. (2009). Polymeric nanoparticulate system: a potential approach for ocular drug delivery. J Control Release 136:2–13
52. Nanjwade VK, Manvi FV, Shamrez AM, et al. (2012). Development and characterization of novel pharmaceutical crystalline complex of lomefloxacin. Int J Drug Dev Res 4:227–33
53. Nounou MM, El-Khordagui LK, Khalafallah NA, Khalil SA., (2006). In vitro release of hydrophilic and hydrophobic drugs from liposomal dispersions and gels. Acta Pharm 56:311–24
54. Padamwar MN, Pokharkar VB., (2006). Development of vitamin loaded topical liposomal formulation using factorial design approach: drug deposition and stability. Int J Pharm 320:37–44
55. Patel A, Cholkar K, Agrahari V, Mitra AK., (2013). Ocular drug delivery systems: an overview. World J Pharmacol 2:47–64
56. Ramos-Cabrer P, Campos F., (2013). Liposomes and nanotechnology in drug development: focus on neurological targets. Int J Nanomedicine 8:951–60
57. Rogerson A, Cummings J, Florence AT., (1987). Adriamycin-loaded niosomes: drug entrapment, stability and release. J Microencapsul 4:321–8
58. Ruckmani K, Sankar V., (2010). Formulation and optimization of Zidovudine niosomes. AAPS PharmSciTech 11:1119–27
59. Ruponen, M, Urtti A., (2015). Undefined role of mucus as a barrier in ocular drug delivery. Eur J Pharm Biopharm 96:442–6
60. Sankhyan A, Pawar PK., (2013). Metformin loaded non-ionic surfactant vesicles: optimization of formulation, effect of process variables and characterization. DARU J Pharm Sci 21:7
61. Santucci V, Storme JJ, Soubrie P, Le Fur G., (1996). Arousal-enhancing properties of the CB1 cannabinoid receptor antagonist SR 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis. Life Sci 58:PL103–10
62. Sato H, Fukuda S, Inatomi M, et al. (1996). [Pharmacokinetics of norfloxacin and lomefloxacin in aqueous humour analysed by microdialysis]. Nippon Ganka Gakkai Zasshi 100:513–19
63. Sattar Z, Saberi MR, Chamani J., (2014). Determination of LMF binding site on a HSA-PPIX complex in the presence of human holo transferrin from the viewpoint of drug loading on proteins. PLoS One 9:e84045
64. Singh D, Pradhan M, Nag M, Singh MR., (2014). Vesicular system: versatile carrier for transdermal delivery of bioactives. Artif Cells Nanomed Biotechnol 43:282–90
65. Symonds WT, Nix DE., (1992). Lomefloxacin and temafloxacin: two new fluoroquinolone antimicrobials. Clin Pharm 11:753–66
66. Taha EI, El-Anazi MH, El-Bagory IM, Bayomi MA., (2014). Design of liposomal colloidal systems for ocular delivery of ciprofloxacin. Saudi Pharm J 22:231–9
67. Tamilvanan S, Benita S., (2004). The potential of lipid emulsion for ocular delivery of lipophilic drugs. Eur J Pharm Biopharm 58:357–68
68. Tavano L, De Cindio B, Picci N, et al. (2014). Drug compartmentalization as strategy to improve the physico-chemical properties of diclofenac sodium loaded niosomes for topical applications. Biomed Microdevices 16:851–858
69. Thakur R, Anwer MK, Shams MS, et al. (2009). Proniosomal transdermal therapeutic system of losartan potassium: development and pharmacokinetic evaluation. J Drug Target 17:442–9
70. Thompson AM., (2007). Ocular toxicity of fluoroquinolones. Clin Experiment Ophthalmol 35:566–77
71. Yasin MN, Hussain S, Malik F, et al. (2012). Preparation and characterization of chloramphenicol niosomes and comparison with chloramphenicol eye drops (0.5%w/v) in experimental conjunctivitis in albino rabbits. Pak J Pharm Sci 25:117–21
72. Ying L, Tahara K, Takeuchi H., (2013). Drug delivery to the ocular posterior segment using lipid emulsion via eye drop administration: effect of emulsion formulations and surface modification. Int J Pharm 453:329–35