메뉴 건너뛰기




Volumn 99, Issue 2, 2004, Pages 241-258

Model of transient drug diffusion across cornea

Author keywords

Anterior chamber; Eye; Ophthalmic drug delivery; Topical; Transport

Indexed keywords

CORNEA; DRUG DELIVERY; LIPOPHILICITY; SOLUTE TRANSIENT DIFFUSION;

EID: 4544339611     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.07.001     Document Type: Article
Times cited : (151)

References (43)
  • 1
    • 82255171252 scopus 로고    scopus 로고
    • Ocular pharmacokinetics and pharmacodynamics
    • A.K. Mitra Marcel Dekker New York
    • R.D. Schoenwald Ocular pharmacokinetics and pharmacodynamics A.K. Mitra Ophthalmic Drug Delivery Systems 2003 Marcel Dekker New York 135 179
    • (2003) Ophthalmic Drug Delivery Systems , pp. 135-179
    • Schoenwald, R.D.1
  • 2
    • 0022852854 scopus 로고
    • Topical ocular drug delivery: Recent developments and future challenges
    • V.H. Lee, and J.R. Robinson Topical ocular drug delivery: recent developments and future challenges J. Ocul. Pharmacol. 2 1 1986 67 108
    • (1986) J. Ocul. Pharmacol. , vol.2 , Issue.1 , pp. 67-108
    • Lee, V.H.1    Robinson, J.R.2
  • 4
    • 0018140352 scopus 로고
    • Preliminary pharmacokinetic model of pilocarpine uptake and distribution in the eye
    • K.J. Himmelstein, I. Guvenir, and T.F. Patton Preliminary pharmacokinetic model of pilocarpine uptake and distribution in the eye J. Pharm. Sci. 67 5 1978 603 606
    • (1978) J. Pharm. Sci. , vol.67 , Issue.5 , pp. 603-606
    • Himmelstein, K.J.1    Guvenir, I.2    Patton, T.F.3
  • 5
    • 0019848890 scopus 로고
    • A physiologically based pharmacokinetic model for the intraocular distribution of pilocarpine in rabbits
    • S.C. Miller, K.J. Himmelstein, and T.F. Patton A physiologically based pharmacokinetic model for the intraocular distribution of pilocarpine in rabbits J. Pharmacokinet. Biopharm. 9 6 1981 653 677
    • (1981) J. Pharmacokinet. Biopharm. , vol.9 , Issue.6 , pp. 653-677
    • Miller, S.C.1    Himmelstein, K.J.2    Patton, T.F.3
  • 6
    • 0031696683 scopus 로고    scopus 로고
    • A fiber matrix model for the permeability of sclera and corneal stroma
    • A. Edwards, and M.R. Prausnitz A fiber matrix model for the permeability of sclera and corneal stroma AIChE J. 44 1998 214 225
    • (1998) AIChE J. , vol.44 , pp. 214-225
    • Edwards, A.1    Prausnitz, M.R.2
  • 7
    • 0034750070 scopus 로고    scopus 로고
    • Predicted permeability of the cornea to topical drugs
    • A. Edwards, and M.R. Prausnitz Predicted permeability of the cornea to topical drugs Pharm. Res. 18 11 2001 1497 1508
    • (2001) Pharm. Res. , vol.18 , Issue.11 , pp. 1497-1508
    • Edwards, A.1    Prausnitz, M.R.2
  • 8
    • 0027193707 scopus 로고
    • A model to predict aqueous humor and plasma pharmacokinetics of ocularly applied drugs
    • G.M. Grass, and V.H. Lee A model to predict aqueous humor and plasma pharmacokinetics of ocularly applied drugs Investig. Ophthalmol. Vis. Sci. 34 7 1993 2251 2259
    • (1993) Investig. Ophthalmol. Vis. Sci. , vol.34 , Issue.7 , pp. 2251-2259
    • Grass, G.M.1    Lee, V.H.2
  • 9
    • 0021842646 scopus 로고
    • Importance of the noncorneal absorption route in topical ophthalmic drug delivery
    • I. Ahmed, and T.F. Patton Importance of the noncorneal absorption route in topical ophthalmic drug delivery Investig. Ophthalmol. Vis. Sci. 26 4 1985 584 587
    • (1985) Investig. Ophthalmol. Vis. Sci. , vol.26 , Issue.4 , pp. 584-587
    • Ahmed, I.1    Patton, T.F.2
  • 11
    • 0015850330 scopus 로고
    • Lacrimal and instilled fluid dynamics in rabbit eyes
    • S.S. Chrai, T.F. Patton, A. Mehta, and J.R. Robinson Lacrimal and instilled fluid dynamics in rabbit eyes J. Pharm. Sci. 62 7 1973 1112 1121
    • (1973) J. Pharm. Sci. , vol.62 , Issue.7 , pp. 1112-1121
    • Chrai, S.S.1    Patton, T.F.2    Mehta, A.3    Robinson, J.R.4
  • 12
    • 0024584107 scopus 로고
    • Paracellular permeability of corneal and conjunctival epithelia
    • A.J. Huang, S.C. Tseng, and K.R. Kenyon Paracellular permeability of corneal and conjunctival epithelia Investig. Ophthalmol. Vis. Sci. 30 4 1989 684 689
    • (1989) Investig. Ophthalmol. Vis. Sci. , vol.30 , Issue.4 , pp. 684-689
    • Huang, A.J.1    Tseng, S.C.2    Kenyon, K.R.3
  • 13
    • 0021072511 scopus 로고
    • Corneal penetration behavior of beta-blocking agents: II. Assessment of barrier contributions
    • H.S. Huang, R.D. Schoenwald, and J.L. Lach Corneal penetration behavior of beta-blocking agents: II. Assessment of barrier contributions J. Pharm. Sci. 72 11 1983 1272 1279
    • (1983) J. Pharm. Sci. , vol.72 , Issue.11 , pp. 1272-1279
    • Huang, H.S.1    Schoenwald, R.D.2    Lach, J.L.3
  • 14
    • 85058108852 scopus 로고    scopus 로고
    • The noncorneal route in ocular drug delivery
    • A.K. Mitra Marcel Dekker New York
    • I. Ahmed The noncorneal route in ocular drug delivery A.K. Mitra Ophthalmic Drug Delivery Systems 2003 Marcel Dekker New York 235 363
    • (2003) Ophthalmic Drug Delivery Systems , pp. 235-363
    • Ahmed, I.1
  • 15
    • 0023745206 scopus 로고
    • Ultrastructure of the paralimbal and juxtacaruncular human conjunctiva
    • R. Breitbach, and M. Spitznas Ultrastructure of the paralimbal and juxtacaruncular human conjunctiva Graefe Arch. Clin. Exp. Ophthalmol. 226 6 1988 567 575
    • (1988) Graefe Arch. Clin. Exp. Ophthalmol. , vol.226 , Issue.6 , pp. 567-575
    • Breitbach, R.1    Spitznas, M.2
  • 16
    • 0842283719 scopus 로고    scopus 로고
    • Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera
    • K. Hamalainen, K. Kananen, S. Auriola, K. Kontturi, and A. Urtti Characterization of paracellular and aqueous penetration routes in cornea, conjunctiva, and sclera Investig. Ophthalmol. Vis. Sci. 38 3 1997 627 634
    • (1997) Investig. Ophthalmol. Vis. Sci. , vol.38 , Issue.3 , pp. 627-634
    • Hamalainen, K.1    Kananen, K.2    Auriola, S.3    Kontturi, K.4    Urtti, A.5
  • 17
    • 0031399120 scopus 로고    scopus 로고
    • Scanning electron microscopy study of the tarsal and orbital conjunctival surfaces compared to peripheral corneal epithelium in pigmented rabbits
    • M.J. Doughty Scanning electron microscopy study of the tarsal and orbital conjunctival surfaces compared to peripheral corneal epithelium in pigmented rabbits Doc. Ophthalmol. 93 4 1997 345 371
    • (1997) Doc. Ophthalmol. , vol.93 , Issue.4 , pp. 345-371
    • Doughty, M.J.1
  • 18
    • 0025775370 scopus 로고
    • Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: A comparison with corneal penetration
    • W. Wang, H. Sasaki, D.S. Chien, and V.H. Lee Lipophilicity influence on conjunctival drug penetration in the pigmented rabbit: a comparison with corneal penetration Curr. Eye Res. 10 6 1991 571 579
    • (1991) Curr. Eye Res. , vol.10 , Issue.6 , pp. 571-579
    • Wang, W.1    Sasaki, H.2    Chien, D.S.3    Lee, V.H.4
  • 21
    • 0036661490 scopus 로고    scopus 로고
    • General purpose antimicrobial ophthalmic solutions evaluated using new pharmacokinetic parameter of maximum drug concentration in aqueous
    • M. Fukuda, and K. Sasaki General purpose antimicrobial ophthalmic solutions evaluated using new pharmacokinetic parameter of maximum drug concentration in aqueous Jpn. J. Ophthalmol. 46 4 2002 384 390
    • (2002) Jpn. J. Ophthalmol. , vol.46 , Issue.4 , pp. 384-390
    • Fukuda, M.1    Sasaki, K.2
  • 22
    • 0021069377 scopus 로고
    • Corneal penetration behavior of beta-blocking agents: III. in vitroâ€"in vivo correlations
    • H.S. Huang, R.D. Schoenwald, and J.L. Lach Corneal penetration behavior of beta-blocking agents: III. In vitroâ€"in vivo correlations J. Pharm. Sci. 72 11 1983 1279 1281
    • (1983) J. Pharm. Sci. , vol.72 , Issue.11 , pp. 1279-1281
    • Huang, H.S.1    Schoenwald, R.D.2    Lach, J.L.3
  • 23
    • 0018778644 scopus 로고
    • Mechanistic and quantitative evaluation of precorneal pilocarpine disposition in albino rabbits
    • V.H. Lee, and J.R. Robinson Mechanistic and quantitative evaluation of precorneal pilocarpine disposition in albino rabbits J. Pharm. Sci. 68 6 1979 673 684
    • (1979) J. Pharm. Sci. , vol.68 , Issue.6 , pp. 673-684
    • Lee, V.H.1    Robinson, J.R.2
  • 24
    • 0017140815 scopus 로고
    • Quantitative precorneal disposition of topically applied pilocarpine nitrate in rabbit eyes
    • T.F. Patton, and J.R. Robinson Quantitative precorneal disposition of topically applied pilocarpine nitrate in rabbit eyes J. Pharm. Sci. 65 9 1976 1295 1301
    • (1976) J. Pharm. Sci. , vol.65 , Issue.9 , pp. 1295-1301
    • Patton, T.F.1    Robinson, J.R.2
  • 25
    • 0025606489 scopus 로고
    • The effect of reduced tear drainage on corneal and aqueous concentrations of topically applied fluorescein
    • C. Linden, and A. Alm The effect of reduced tear drainage on corneal and aqueous concentrations of topically applied fluorescein Acta Ophthalmol. 68 6 1990 633 638
    • (1990) Acta Ophthalmol. , vol.68 , Issue.6 , pp. 633-638
    • Linden, C.1    Alm, A.2
  • 26
    • 0031772606 scopus 로고    scopus 로고
    • Permeability of cornea, sclera, and conjunctiva: A literature analysis for drug delivery to the eye
    • M.R. Prausnitz, and J.S. Noonan Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye J. Pharm. Sci. 87 12 1998 1479 1488
    • (1998) J. Pharm. Sci. , vol.87 , Issue.12 , pp. 1479-1488
    • Prausnitz, M.R.1    Noonan, J.S.2
  • 27
    • 0022499648 scopus 로고
    • Ocular pharmacokinetic models of clonidine-3H hydrochloride
    • C.H. Chiang, and R.D. Schoenwald Ocular pharmacokinetic models of clonidine-3H hydrochloride J. Pharmacokinet. Biopharm. 14 2 1986 175 211
    • (1986) J. Pharmacokinet. Biopharm. , vol.14 , Issue.2 , pp. 175-211
    • Chiang, C.H.1    Schoenwald, R.D.2
  • 29
    • 0026563412 scopus 로고
    • Effect of nasolacrimal occlusion on timolol concentrations in the aqueous humor of the human eye
    • P.P. Ellis, P.Y. Wu, D.S. Pfoff, D.C. Bloedow, and M.R. Riegel Effect of nasolacrimal occlusion on timolol concentrations in the aqueous humor of the human eye J. Pharm. Sci. 81 3 1992 219 220
    • (1992) J. Pharm. Sci. , vol.81 , Issue.3 , pp. 219-220
    • Ellis, P.P.1    Wu, P.Y.2    Pfoff, D.S.3    Bloedow, D.C.4    Riegel, M.R.5
  • 31
    • 0023631404 scopus 로고
    • Disposition of levobunolol after an ophthalmic dose to rabbits
    • D.D. Tang-Liu, S. Liu, J. Neff, and R. Sandri Disposition of levobunolol after an ophthalmic dose to rabbits J. Pharm. Sci. 76 10 1987 780 783
    • (1987) J. Pharm. Sci. , vol.76 , Issue.10 , pp. 780-783
    • Tang-Liu, D.D.1    Liu, S.2    Neff, J.3    Sandri, R.4
  • 32
  • 33
    • 0034978842 scopus 로고    scopus 로고
    • A compartment model to calculate time-dependent concentration profiles of topically applied chemical compounds in the anterior compartments of the rabbit eye
    • H. Pospisil, and H.G. Holzhutter A compartment model to calculate time-dependent concentration profiles of topically applied chemical compounds in the anterior compartments of the rabbit eye Altern. Lab. Anim. 29 3 2001 347 365
    • (2001) Altern. Lab. Anim. , vol.29 , Issue.3 , pp. 347-365
    • Pospisil, H.1    Holzhutter, H.G.2
  • 35
    • 0344629343 scopus 로고    scopus 로고
    • Ocular absorption of Pz-peptide and its effect on the ocular and systemic pharmacokinetics of topically applied drugs in the rabbit
    • Y.B. Chung, K. Han, A. Nishiura, and V.H. Lee Ocular absorption of Pz-peptide and its effect on the ocular and systemic pharmacokinetics of topically applied drugs in the rabbit Pharm. Res. 15 12 1998 1882 1887
    • (1998) Pharm. Res. , vol.15 , Issue.12 , pp. 1882-1887
    • Chung, Y.B.1    Han, K.2    Nishiura, A.3    Lee, V.H.4
  • 36
    • 0023553501 scopus 로고
    • Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea
    • I. Ahmed, R.D. Gokhale, M.V. Shah, and T.F. Patton Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea J. Pharm. Sci. 76 8 1987 583 586
    • (1987) J. Pharm. Sci. , vol.76 , Issue.8 , pp. 583-586
    • Ahmed, I.1    Gokhale, R.D.2    Shah, M.V.3    Patton, T.F.4
  • 37
    • 0024463731 scopus 로고
    • Transport mechanisms of the cornea: Characterization of barrier permselectivity
    • Y. Rojanasakul, and J.R. Robinson Transport mechanisms of the cornea: characterization of barrier permselectivity Int. J. Pharm. 55 2â€"3 1989 237 246
    • (1989) Int. J. Pharm. , vol.55 , Issue.23 , pp. 237-246
    • Rojanasakul, Y.1    Robinson, J.R.2
  • 38
    • 0023918338 scopus 로고
    • Comparison of conjunctival and corneal surface areas in rabbit and human
    • M.A. Watsky, M.M. Jablonski, and H.F. Edelhauser Comparison of conjunctival and corneal surface areas in rabbit and human Curr. Eye Res. 7 5 1988 483 486
    • (1988) Curr. Eye Res. , vol.7 , Issue.5 , pp. 483-486
    • Watsky, M.A.1    Jablonski, M.M.2    Edelhauser, H.F.3
  • 39
    • 0018966248 scopus 로고
    • Volume and depth of the anterior chamber in the normal aging human eye
    • S.T. Fontana, and R.F. Brubaker Volume and depth of the anterior chamber in the normal aging human eye Arch. Ophthalmol. 98 10 1980 1803 1808
    • (1980) Arch. Ophthalmol. , vol.98 , Issue.10 , pp. 1803-1808
    • Fontana, S.T.1    Brubaker, R.F.2
  • 40
    • 0000152455 scopus 로고
    • Pharmacokinetics in ocular drug delivery
    • P. Edman CRC Press Boca Raton, FL
    • R.D. Schoenwald Pharmacokinetics in ocular drug delivery P. Edman Biopharmaceutics of Ocular Drug Delivery 1993 CRC Press Boca Raton, FL 159 191
    • (1993) Biopharmaceutics of Ocular Drug Delivery , pp. 159-191
    • Schoenwald, R.D.1
  • 41
    • 0022448785 scopus 로고
    • Improving the ocular absorption of phenylephrine
    • D.S. Chien, and R.D. Schoenwald Improving the ocular absorption of phenylephrine Biopharm. Drug Dispos. 7 5 1986 453 462
    • (1986) Biopharm. Drug Dispos. , vol.7 , Issue.5 , pp. 453-462
    • Chien, D.S.1    Schoenwald, R.D.2
  • 42
    • 0021712459 scopus 로고
    • Ocular and systemic bioavailability of ophthalmic flurbiprofen
    • D.D. Tang-Liu, S.S. Liu, and R.J. Weinkam Ocular and systemic bioavailability of ophthalmic flurbiprofen J. Pharmacokinet. Biopharm. 12 6 1984 611 626
    • (1984) J. Pharmacokinet. Biopharm. , vol.12 , Issue.6 , pp. 611-626
    • Tang-Liu, D.D.1    Liu, S.S.2    Weinkam, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.