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Volumn 101, Issue 4, 2016, Pages 1422-1428

Adipose tissue hypoxia, inflammation, and fibrosis in obese insulin-sensitive and obese insulin-resistant subjects

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CD68 ANTIGEN; COLLAGEN TYPE 6; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LEPTIN; MATRILYSIN; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; SCAVENGER RECEPTOR A; TUMOR NECROSIS FACTOR; VASCULOTROPIN; ANTIDIABETIC AGENT; INSULIN;

EID: 85011278150     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2015-4125     Document Type: Article
Times cited : (135)

References (31)
  • 1
    • 84863586953 scopus 로고    scopus 로고
    • Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality
    • Hamer M, Stamatakis E. Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality. J Clin Endocrinol Metab. 2012;97(7):2482-2488.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.7 , pp. 2482-2488
    • Hamer, M.1    Stamatakis, E.2
  • 2
    • 77649171169 scopus 로고    scopus 로고
    • The distinction of metabolically 'healthy' from 'unhealthy' obese individuals
    • Bluher M. The distinction of metabolically 'healthy' from 'unhealthy' obese individuals. Curr Opin Lipidol. 2010;21(1):38-43.
    • (2010) Curr Opin Lipidol , vol.21 , Issue.1 , pp. 38-43
    • Bluher, M.1
  • 3
    • 84885647821 scopus 로고    scopus 로고
    • Metabolically healthy obesity: Definitions, determinants and clinical implications
    • Phillips C. Metabolically healthy obesity: Definitions, determinants and clinical implications. Rev Endocr Metab Disord. 2013;14(3):219-227.
    • (2013) Rev Endocr Metab Disord , vol.14 , Issue.3 , pp. 219-227
    • Phillips, C.1
  • 4
    • 79957916782 scopus 로고    scopus 로고
    • Adipose tissue remodeling and obesity
    • Sun K, Kusminski CM, Scherer PE. Adipose tissue remodeling and obesity. J Clin Invest. 2011;121(6):2094-2101.
    • (2011) J Clin Invest , vol.121 , Issue.6 , pp. 2094-2101
    • Sun, K.1    Kusminski, C.M.2    Scherer, P.E.3
  • 5
    • 55649105421 scopus 로고    scopus 로고
    • Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women
    • McLaughlin T, Deng A, Gonzales O, et al. Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women. Diabetologia. 2008;51(12):2303-2308.
    • (2008) Diabetologia , vol.51 , Issue.12 , pp. 2303-2308
    • McLaughlin, T.1    Deng, A.2    Gonzales, O.3
  • 6
    • 79953883054 scopus 로고    scopus 로고
    • Preadipocyte factor-1 is associated with metabolic profile in severe obesity
    • O'Connell J, Lynch L, Hogan A, Cawood TJ, O'Shea D. Preadipocyte factor-1 is associated with metabolic profile in severe obesity. J Clin Endocrinol Metab. 2011;96(4):E680-E684.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.4 , pp. E680-E684
    • O'Connell, J.1    Lynch, L.2    Hogan, A.3    Cawood, T.J.4    O'Shea, D.5
  • 7
    • 84859412650 scopus 로고    scopus 로고
    • Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue
    • Xu XJ, Gauthier MS, Hess DT, et al. Insulin sensitive and resistant obesity in humans: AMPK activity, oxidative stress, and depot-specific changes in gene expression in adipose tissue. J Lipid Res. 2012;53(4):792-801.
    • (2012) J Lipid Res , vol.53 , Issue.4 , pp. 792-801
    • Xu, X.J.1    Gauthier, M.S.2    Hess, D.T.3
  • 8
    • 62749167010 scopus 로고    scopus 로고
    • Reduced adipose tissue oxygenation in human obesity: Evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response
    • Pasarica M, Sereda OR, Redman LM, et al. Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response. Diabetes. 2009;58(3):718-725.
    • (2009) Diabetes , vol.58 , Issue.3 , pp. 718-725
    • Pasarica, M.1    Sereda, O.R.2    Redman, L.M.3
  • 10
    • 58149500277 scopus 로고    scopus 로고
    • Emerging role of adipose tissue hypoxia in obesity and insulin resistance
    • Ye J. Emerging role of adipose tissue hypoxia in obesity and insulin resistance. Int J Obes (Lond). 2009;33(1):54-66.
    • (2009) Int J Obes (Lond) , vol.33 , Issue.1 , pp. 54-66
    • Ye, J.1
  • 11
    • 34047119110 scopus 로고    scopus 로고
    • Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
    • Hosogai N, Fukuhara A, Oshima K, et al. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes. 2007;56(4):901-911.
    • (2007) Diabetes , vol.56 , Issue.4 , pp. 901-911
    • Hosogai, N.1    Fukuhara, A.2    Oshima, K.3
  • 12
    • 63249093556 scopus 로고    scopus 로고
    • Hypoxia decreases insulin signaling pathways in adipocytes
    • Regazzetti C, Peraldi P, Gremeaux T, et al. Hypoxia decreases insulin signaling pathways in adipocytes. Diabetes. 2009;58(1):95-103.
    • (2009) Diabetes , vol.58 , Issue.1 , pp. 95-103
    • Regazzetti, C.1    Peraldi, P.2    Gremeaux, T.3
  • 14
    • 0347624611 scopus 로고    scopus 로고
    • MINMOD Millennium: A computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test
    • Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN. MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technol Ther. 2003;5(6):1003-1015.
    • (2003) Diabetes Technol Ther , vol.5 , Issue.6 , pp. 1003-1015
    • Boston, R.C.1    Stefanovski, D.2    Moate, P.J.3    Sumner, A.E.4    Watanabe, R.M.5    Bergman, R.N.6
  • 15
    • 23644446750 scopus 로고    scopus 로고
    • Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: Association with cytokine expression, insulin resistance, and reduction by pioglitazone
    • Di Gregorio GB, Yao-Borengasser A, Rasouli N, et al. Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes. 2005;54(8):2305-2313.
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2305-2313
    • Di Gregorio, G.B.1    Yao-Borengasser, A.2    Rasouli, N.3
  • 16
    • 69849113860 scopus 로고    scopus 로고
    • Association of scavenger receptors in adipose tissue with insulin resistance in nondiabetic humans
    • Rasouli N, Yao-Borengasser A, Varma V, et al. Association of scavenger receptors in adipose tissue with insulin resistance in nondiabetic humans. Arterioscler Thromb Vasc Biol. 2009;29(9):1328-1335.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.9 , pp. 1328-1335
    • Rasouli, N.1    Yao-Borengasser, A.2    Varma, V.3
  • 17
    • 57349136290 scopus 로고    scopus 로고
    • Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness
    • Yao-Borengasser A, Rassouli N, Varma V, et al. Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness. J Clin Endocrinol Metab. 2008;93(11):4431-4439.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.11 , pp. 4431-4439
    • Yao-Borengasser, A.1    Rassouli, N.2    Varma, V.3
  • 18
    • 83155187250 scopus 로고    scopus 로고
    • Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance
    • Spencer M, Unal R, Zhu B, et al. Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance. J Clin Endocrinol Metab. 2011;96(12):E1990-E1998.
    • (2011) J Clin Endocrinol Metab , vol.96 , Issue.12 , pp. E1990-E1998
    • Spencer, M.1    Unal, R.2    Zhu, B.3
  • 19
    • 79959367267 scopus 로고    scopus 로고
    • Adipose triglyceride lipase expression in human adipose tissue and muscle. Role in insulin resistance and response to training and pioglitazone
    • Yao-Borengasser A, Varma VF, Coker RH, et al. Adipose triglyceride lipase expression in human adipose tissue and muscle. Role in insulin resistance and response to training and pioglitazone. Metabolism. 2011;60(7):1012-1020.
    • (2011) Metabolism , vol.60 , Issue.7 , pp. 1012-1020
    • Yao-Borengasser, A.1    Varma, V.F.2    Coker, R.H.3
  • 20
    • 40749150741 scopus 로고    scopus 로고
    • Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance
    • Varma V, Yao-Borengasser A, Bodles AM, et al. Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance. Diabetes. 2008;57(2):432-439.
    • (2008) Diabetes , vol.57 , Issue.2 , pp. 432-439
    • Varma, V.1    Yao-Borengasser, A.2    Bodles, A.M.3
  • 21
    • 55849114349 scopus 로고    scopus 로고
    • Adipocytokines and the metabolic complications of obesity
    • Rasouli N, Kern PA. Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab. 2008;93(11 suppl 1):S64-S73.
    • (2008) J Clin Endocrinol Metab , vol.93 , Issue.11 , pp. S64-S73
    • Rasouli, N.1    Kern, P.A.2
  • 22
    • 84866133825 scopus 로고    scopus 로고
    • Adiponectin: Mechanistic insights and clinical implications
    • Turer AT, Scherer PE. Adiponectin: mechanistic insights and clinical implications. Diabetologia. 2012;55(9):2319-2326.
    • (2012) Diabetologia , vol.55 , Issue.9 , pp. 2319-2326
    • Turer, A.T.1    Scherer, P.E.2
  • 23
    • 62849107819 scopus 로고    scopus 로고
    • Metabolic dysregulation and adipose tissue fibrosis: Role of collagen VI
    • Khan T, Muise ES, Iyengar P, et al. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Mol Cell Biol. 2009;29(6):1575-1591.
    • (2009) Mol Cell Biol , vol.29 , Issue.6 , pp. 1575-1591
    • Khan, T.1    Muise, E.S.2    Iyengar, P.3
  • 24
    • 78649652068 scopus 로고    scopus 로고
    • Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation
    • Spencer M, Yao-Borengasser A, Unal R, et al. Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation. Am J Physiol Endocrinol Metab. 2010;299(6):E1016-E1027.
    • (2010) Am J Physiol Endocrinol Metab , vol.299 , Issue.6 , pp. E1016-E1027
    • Spencer, M.1    Yao-Borengasser, A.2    Unal, R.3
  • 25
    • 0036227213 scopus 로고    scopus 로고
    • Modulation of adipose tissue expression of murine matrix metalloproteinases and their tissue inhibitors with obesity
    • Maquoi E, Munaut C, Colige A, Collen D, Lijnen HR. Modulation of adipose tissue expression of murine matrix metalloproteinases and their tissue inhibitors with obesity. Diabetes. 2002;51(4):1093-1101.
    • (2002) Diabetes , vol.51 , Issue.4 , pp. 1093-1101
    • Maquoi, E.1    Munaut, C.2    Colige, A.3    Collen, D.4    Lijnen, H.R.5
  • 26
    • 84930659522 scopus 로고    scopus 로고
    • Adipose tissue dysfunction and impaired metabolic health in human obesity: A matter of oxygen?
    • Goossens GH, Blaak EE. Adipose tissue dysfunction and impaired metabolic health in human obesity: a matter of oxygen? Front Endocrinol (Lausanne). 2015;6:55.
    • (2015) Front Endocrinol (Lausanne) , vol.6 , pp. 55
    • Goossens, G.H.1    Blaak, E.E.2
  • 27
    • 84893398146 scopus 로고    scopus 로고
    • Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity - Fibrosis and adipose tissue dysfunction
    • Lackey DE, Burk DH, Ali MR, et al. Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity - fibrosis and adipose tissue dysfunction. Am J Physiol Endocrinol Metab. 2014;306(3):E233-E246.
    • (2014) Am J Physiol Endocrinol Metab , vol.306 , Issue.3 , pp. E233-E246
    • Lackey, D.E.1    Burk, D.H.2    Ali, M.R.3
  • 28
    • 0035023128 scopus 로고    scopus 로고
    • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
    • Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab. 2001;280(5):E745-E751.
    • (2001) Am J Physiol Endocrinol Metab , vol.280 , Issue.5 , pp. E745-E751
    • Kern, P.A.1    Ranganathan, S.2    Li, C.3    Wood, L.4    Ranganathan, G.5
  • 29
    • 0034871316 scopus 로고    scopus 로고
    • Leptin concentrations in the United States: Relations with demographic and anthropometric measures
    • Ruhl CE, Everhart JE. Leptin concentrations in the United States: relations with demographic and anthropometric measures. Am J Clin Nutr. 2001;74(3):295-301.
    • (2001) Am J Clin Nutr , vol.74 , Issue.3 , pp. 295-301
    • Ruhl, C.E.1    Everhart, J.E.2
  • 30
    • 79951829343 scopus 로고    scopus 로고
    • Hypoxia and Inflammation
    • Eltzschig HK, Carmeliet P. Hypoxia and Inflammation. N Engl J Med. 2011;364(7):656-665.
    • (2011) N Engl J Med , vol.364 , Issue.7 , pp. 656-665
    • Eltzschig, H.K.1    Carmeliet, P.2
  • 31
    • 84872290190 scopus 로고    scopus 로고
    • Hypoxia and adipose tissue function and dysfunction in obesity
    • Trayhurn P. Hypoxia and adipose tissue function and dysfunction in obesity. Physiol Rev. 2013;93(1):1-21.
    • (2013) Physiol Rev , vol.93 , Issue.1 , pp. 1-21
    • Trayhurn, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.