Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance

Journal of Clinical Endocrinology and Metabolism

Volumn 96, Issue 12, 2011, Pages

  Spencer, Michael ^a   Unal, Resat ^a   Zhu, Beibei ^a   Rasouli, Neda ^c   McGehee Jr , Robert E ^d   Peterson, Charlotte A ^b   Kern, Philip A ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; CD31 ANTIGEN; COLLAGEN; COLLAGEN TYPE 5; ELASTIN; MESSENGER RNA;

ABDOMINAL SUBCUTANEOUS FAT; ADIPOCYTE; ADIPOSE TISSUE; ADULT; ANGIOGENESIS; ARTICLE; BIOPSY; BLOOD VESSEL; BODY MASS; CAPILLARY; COCULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; INSULIN SENSITIVITY; MACROPHAGE; MALE; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR DISEASE;

ADIPOSE TISSUE; ADULT; ANTIGENS, CD31; BODY COMPOSITION; BODY MASS INDEX; CAPILLARIES; COLLAGEN; ELASTIN; EXTRACELLULAR MATRIX; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INFLAMMATION; INSULIN RESISTANCE; MALE; OBESITY;

EID: 83155187250     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-1567     Document Type: Article

References (44)

1. de Luca C, Olefsky JM 2008 Inflammation and insulin resistance. FEBS Lett 582:97-105 (Pubitemid 50010731)
2. Kahn SE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP 1993 Quantification of the relationship between insulin sensitivity and β-cell function in human subjects. Evidence for a hyperbolic function. Diabetes 42:1663-1672 (Pubitemid 23318125)
3. Lee MJ, Wu Y, Fried SK 2010 Adipose tissue remodeling in pathophysiology of obesity. Curr Opin Clin Nutr Metab Care 13:371-376
4. Suganami T, Ogawa Y 2010 Adipose tissue macrophages: their role in adipose tissue remodeling. J Leukoc Biol 88:33-39
5. Varma V, Yao-Borengasser A, Bodles AM, Rasouli N, Phanavanh B, Nolen GT, Kern EM, Nagarajan R, Spencer HJ 3rd, Lee MJ, Fried SK, McGehee RE Jr, Peterson CA, Kern PA 2008 Thrombospondin- 1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance. Diabetes 57:432-439
6. Spencer M, Yao-Borengasser A, Unal R, Rasouli N, Gurley CM, Zhu B, Peterson CA, Kern PA 2010 Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation. Am J Physiol Endocrinol Metab 299:E1016-E1027
7. Pasarica M, Gowronska-Kozak B, Burk D, Remedios I, Hymel D, Gimble J, Ravussin E, Bray GA, Smith SR 2009 Adipose tissue collagen VI in obesity. J Clin Endocrinol Metab 94:5155-5162
8. Trayhurn P, Wood IS 2004 Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 92:347-355 (Pubitemid 40277057)
9. Pasarica M, Sereda OR, Redman LM, Albarado DC, Hymel DT, Roan LE, Rood JC, Burk DH, Smith SR 2009 Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response. Diabetes 58:718-725
10. Rutkowski JM, Davis KE, Scherer PE 2009 Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue. FEBS J 276:5738-5746
11. Hosogai N, Fukuhara A, Oshima K, Miyata Y, Tanaka S, Segawa K, Furukawa S, Tochino Y, Komuro R, Matsuda M, Shimomura I 2007 Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes 56:901-911 (Pubitemid 46525054)
12. Pang C, Gao Z, Yin J, Zhang J, Jia W, Ye J 2008 Macrophage infiltration into adipose tissue may promote angiogenesis for adipose tissue remodeling in obesity. Am J Physiol Endocrinol Metab 295:E313-E322
13. Kampf C, Bodin B, Källskog O, Carlsson C, Jansson L 2005 Marked increase in white adipose tissue blood perfusion in the type 2 diabetic GK rat. Diabetes 54:2620-2627 (Pubitemid 41233583)
14. Balwierz A, Polus A, Razny U, Wator L, Dyduch G, Tomaszewska R, Scherneck S, Joost H, Dembinska-Kiec A 2009 Angiogenesis in the New Zealand obese mouse model fed with high fat diet. Lipids Health Dis 8:13
15. Khan T, Muise ES, Iyengar P, Wang ZV, Chandalia M, Abate N, Zhang BB, Bonaldo P, Chua S, Scherer PE 2009 Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI. Mol Cell Biol 29:1575-1591
16. Virtue S, Vidal-Puig A 2010 Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome-an allostatic perspective. Biochim Biophys Acta 1801:338-349
17. Divoux A, Tordjman J, Lacasa D, Veyrie N, Hugol D, Aissat A, Basdevant A, Guerre-Millo M, Poitou C, Zucker JD, Bedossa P, Clément K 2010 Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss. Diabetes 59:2817-2825
18. Ucuzian AA, Gassman AA, East AT, Greisler HP 2010 Molecular mediators of angiogenesis. J Burn Care Res 31:158-175
19. Egeblad M, Werb Z 2002 New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2:161-174 (Pubitemid 37328786)
20. Boston RC, Stefanovski D, Moate PJ, Sumner AE, Watanabe RM, Bergman RN 2003 MINMOD Millennium: a computer program to calculate glucose effectiveness and insulin sensitivity from the frequently sampled intravenous glucose tolerance test. Diabetes Technol Ther 5:1003-1015 (Pubitemid 38009940)
21. Di Gregorio GB, Yao-Borengasser A, Rasouli N, Varma V, Lu T, Miles LM, Ranganathan G, Peterson CA, McGehee RE, Kern PA 2005 Expression of CD68 and macrophage chemoattractant protein- 1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes 54:2305-2313 (Pubitemid 41134256)
22. Almendro N, Bellón T, Rius C, Lastres P, Langa C, Corbí A, Bernabéu C 1996 Cloning of the human platelet endothelial cell adhesion molecule-1 promoter and its tissue-specific expression. Structural and functional characterization. J Immunol 157:5411-5421 (Pubitemid 126448960)
23. Rasouli N, Yao-Borengasser A, Varma V, Spencer HJ, McGehee RE Jr, Peterson CA, Mehta JL, Kern PA 2009 Association of scavenger receptors in adipose tissue with insulin resistance in nondiabetic humans. Arterioscler Thromb Vasc Biol 29:1328-1335
24. Trayhurn P, Wang B, Wood IS 2008 Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br J Nutr 100:227-235
25. Fichard A, Kleman JP, Ruggiero F 1995 Another look at collagen V and XI molecules. Matrix Biol 14:515-531
26. Rasouli N, Kern PA 2008 Adipocytokines and the metabolic complications of obesity. J Clin Endocrinol Metab 93:S64-S73
27. Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS 1997 Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature 389:610-614 (Pubitemid 27446179)
28. Kanda H, Tateya S, Tamori Y, Kotani K, Hiasa K, Kitazawa R, Kitazawa S, Miyachi H, Maeda S, Egashira K, Kasuga M 2006 MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116: 1494-1505
29. Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante Jr AW 2005 CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 116: 115-124 (Pubitemid 43121796)
30. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante Jr AW 2003 Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796-1808 (Pubitemid 38063703)
31. Lumeng CN, Bodzin JL, Saltiel AR 2007 Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117:175-184 (Pubitemid 46048464)
32. Prieur X, Mok CY, Velagapudi VR, Núñez V, Fuentes L, Montaner D, Ishikawa K, Camacho A, Barbarroja N, O'Rahilly S, Sethi JK, Dopazo J, Orešič M, Ricote M, Vidal-Puig A 2011 Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and m2/m1 polarization in obese mice. Diabetes 60:797-809
33. Kawanishi N, Yano H, Yokogawa Y, Suzuki K 2010 Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice. Exerc Immunol Rev 16:105-118
34. Zeyda M, Farmer D, Todoric J, Aszmann O, Speiser M, Györi G, Zlabinger GJ, Stulnig TM 2007 Humanadipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Int J Obes (Lond) 31: 1420-1428 (Pubitemid 47339934)
35. Elbein SC, Kern PA, Rasouli N, Yao-Borengasser A, Sharma NK, Das SK 2011 Global gene expression profiles of subcutaneous adipose and muscle from glucose-tolerant, insulin-sensitive, and insulin- resistant individuals matched for BMI. Diabetes 60:1019-1029
36. Sun K, Kusminski CM, Scherer PE 2011 Adipose tissue remodeling and obesity. J Clin Invest 121:2094-2101
37. Chun TH, Hotary KB, Sabeh F, Saltiel AR, Allen ED, Weiss SJ 2006 A pericellular collagenase directs the 3-dimensional development of white adipose tissue. Cell 125:577-591
38. Unal R, Yao-Borengasser A, Varma V, Rasouli N, Labbate C, Kern PA, Ranganathan G 2010 Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone. J Clin Endocrinol Metab 95:2993-3001
39. Henegar C, Tordjman J, Achard V, Lacasa D, Cremer I, Guerre- Millo M, Poitou C, Basdevant A, Stich V, Viguerie N, Langin D, Bedossa P, Zucker JD, Clement K 2008 Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity. Genome Biol 9:R14
40. Davis GE, Senger DR 2005 Endothelial extracellular matrix: biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ Res 97:1093-1107
41. Yamamoto K, Yamamoto M, Noumura T 1992 Disassembly of F-actin filaments in human endothelial cells cultured on type V collagen. Exp Cell Res 201:55-63
42. Mumby SM, Raugi GJ, Bornstein P 1984 Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen. J Cell Biol 98:646-652 (Pubitemid 14193299)
43. Voskerician G, Anderson JM, Ziats NP 1997 Inhibition of migration of endothelial cells by type V collagen and high molecular weight kininogens. Biomed Sci Instrum 33:172-177 (Pubitemid 28181481)
44. Bezerra MC, Teodoro WR, de Oliveira CC, Velosa AP, Ogido LT, Gauditano G, Parra ER, Capelozzi VL, Yoshinari NH 2006 Scleroderma- like remodeling induced by type V collagen. Arch Dermatol Res 298:51-57 (Pubitemid 43780143)